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Research Article

Dose dependent cytotoxicity of pranoprofen in cultured human corneal endothelial cells by inducing apoptosis

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Pages 16-21 | Received 16 Mar 2013, Accepted 18 Feb 2014, Published online: 18 Mar 2014

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Read on this site (3)

Guo-Jian Jiang & Ting-Jun Fan. (2020) Novel techniques to prevent apoptosis and improve regeneration in corneal endothelial cells. Expert Review of Ophthalmology 15:5, pages 267-274.
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Zhan Song & Ting-Jun Fan. (2018) Tetracaine induces apoptosis through a mitochondrion-dependent pathway in human corneal stromal cells in vitro. Cutaneous and Ocular Toxicology 37:4, pages 350-358.
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Jun-Wei Shen, Ming Shan, Yuan-Yuan Peng & Ting-Jun Fan. (2017) Cytotoxic Effect of Latanoprost on Human Corneal Stromal Cells in vitro and its Possible Mechanisms. Current Eye Research 42:4, pages 534-541.
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Articles from other publishers (14)

Yang Luo, Lu Yang, Peipei Feng, Haofeng Qiu, Xujin Wu, Shuwei Lu, Mi Zhou, Long Xu & Yabin Zhu. (2020) Pranoprofen Nanoparticles With Poly(L-Lactide)-b-Poly(Ethylene Glycol)-b-Poly(L-Lactide) as the Matrix Toward Improving Ocular Anti-inflammation. Frontiers in Bioengineering and Biotechnology 8.
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Ting Yang, Ting-Jun Fan & Bin Xu. (2020) Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells. Toxicology in Vitro 66, pages 104868.
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Yani Lin, Miaomiao Yu & Tingjun Fan. (2020) Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells. Toxicology Letters 320, pages 9-18.
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Ting-Jun Fan, Shu-Xian Wu & Guo-Jian Jiang. (2019) Apoptotic effects of norfloxacin on corneal endothelial cells. Naunyn-Schmiedeberg's Archives of Pharmacology 393:1, pages 77-88.
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Xin-Guo You, Ting-Jun Fan & Guo-Jian Jiang. (2019) Phenylephrine induces necroptosis and apoptosis in corneal epithelial cells dose- and time-dependently. Toxicology 428, pages 152305.
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Guojian Jiang & Tingjun Fan. (2018) Sodium Ferulate Attenuates Lidocaine-Induced Corneal Endothelial Impairment. Oxidative Medicine and Cellular Longevity 2018, pages 1-8.
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Su-Ran Bai & Ting-Jun Fan. (2017) Cytotoxic effect of proparacaine on human corneal epithelial cells and its possible mechanisms. Molecular & Cellular Toxicology 13:1, pages 29-36.
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Eun Young Choi, Hyun Goo Kang, Tae-im Kim, Eung Kwoen Kim & Hyung Keun Lee. (2016) Effect of postoperative administration of nonsteroidal antiinflammatory drugs and steroids on the conformational changes in wound healing after cataract surgery. Journal of Cataract and Refractive Surgery 42:12, pages 1804-1813.
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Ming Shan & Ting-Jun Fan. (2016) Cytotoxicity of carteolol to human corneal epithelial cells by inducing apoptosis via triggering the Bcl-2 family protein-mediated mitochondrial pro-apoptotic pathway. Toxicology in Vitro 35, pages 36-42.
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Cristina Cañadas, Helen Alvarado, Ana C. Calpena, Amélia M. Silva, Eliana B. Souto, Maria L. García & Guadalupe Abrego. (2016) In vitro , ex vivo and in vivo characterization of PLGA nanoparticles loading pranoprofen for ocular administration. International Journal of Pharmaceutics 511:2, pages 719-727.
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Jun Zhao, Yue Qiu, Cheng-Lei Tian & Ting-Jun Fan. (2016) The cytotoxic and pro-apoptotic effects of phenylephrine on corneal stromal cells via a mitochondrion-dependent pathway both in vitro and in vivo. Experimental and Toxicologic Pathology 68:7, pages 409-417.
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Qian Wen, Ting-Jun Fan & Cheng-Lei Tian. (2016) Cytotoxicity of atropine to human corneal endothelial cells by inducing mitochondrion-dependent apoptosis. Experimental Biology and Medicine 241:13, pages 1457-1465.
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Cheng-Lei Tian, Qian Wen & Ting-Jun Fan. (2015) Cytotoxicity of atropine to human corneal epithelial cells by inducing cell cycle arrest and mitochondrion-dependent apoptosis. Experimental and Toxicologic Pathology 67:10, pages 517-524.
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Qian Wen, Tingjun Fan, Suran Bai & Yunlong Sui. (2015) Cytotoxicity of proparacaine to human corneal endothelial cells <i>in vitro </i>. The Journal of Toxicological Sciences 40:4, pages 427-436.
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