1,293
Views
43
CrossRef citations to date
0
Altmetric
Review Article

2C-I-NBOMe, an “N-bomb” that kills with “Smiles”. Toxicological and legislative aspects

, , , &
Pages 113-119 | Received 05 Nov 2013, Accepted 01 Apr 2014, Published online: 01 May 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

CS Johnson, Z Shadfar, JR Allison, KAJ Walsh & HK Partington. (2023) Controlling new psychoactive substances in New Zealand. Australian Journal of Forensic Sciences 55:5, pages 670-688.
Read now
Monika Herian & Paweł Świt. (2023) 25X-NBOMe compounds – chemistry, pharmacology and toxicology. A comprehensive review. Critical Reviews in Toxicology 53:1, pages 15-33.
Read now
Kyung Sik Yoon, Sun Mi Gu, Hye Jin Cha, Young-Hoon Kim, Jaesuk Yun & Jin-Moo Lee. (2022) 25I-NBOMe, a phenethylamine derivative, induces adverse cardiovascular effects in rodents: possible involvement of p21 (CDC42/RAC)-activated kinase 1. Drug and Chemical Toxicology 45:2, pages 898-906.
Read now
Justin L. Poklis, Carl E. Wolf, Carrol R. Nanco & Alphonse Poklis. (2016) Recommendations for specimen collection for NBOMe analysis in clinical toxicology. Clinical Toxicology 54:2, pages 161-162.
Read now
Paul Gee, Leo J. Schep, Berit P. Jensen, Grant Moore & Stuart Barrington. (2016) Case series: toxicity from 25B-NBOMe – a cluster of N-bomb cases. Clinical Toxicology 54:2, pages 141-146.
Read now

Articles from other publishers (38)

Kateřina Syrová, Klára Šíchová, Hynek Danda, Eva Lhotková, Pascal Jorratt, Nikola Pinterová-Leca, Čestmír Vejmola, Lucie Olejníková-Ladislavová, Kateřina Hájková, Martin Kuchař, Jiří Horáček & Tomáš Páleníček. (2023) Acute pharmacological profile of 2C-B-Fly-NBOMe in male Wistar rats—pharmacokinetics, effects on behaviour and thermoregulation. Frontiers in Pharmacology 14.
Crossref
Konstantin A. Demin, Olga V. Kupriyanova, Vadim A. Shevyrin, Ksenia A. Derzhavina, Nataliya A. Krotova, Nikita P. Ilyin, Tatiana O. Kolesnikova, David S. Galstyan, Yurii M. Kositsyn, Abubakar-Askhab S. Khaybaev, Maria V. Seredinskaya, Yaroslav Dubrovskii, Raziya G. Sadykova, Maria O. Nerush, Mikael S. Mor, Elena V. Petersen, Tatyana Strekalova, Evgeniya V. Efimova, Savelii R. Kuvarzin, Konstantin B. Yenkoyan, Dmitrii V. Bozhko, Vladislav O. Myrov, Sofia M. Kolchanova, Aleksander I. Polovian, Georgii K. Galumov & Allan V. Kalueff. (2022) Acute behavioral and Neurochemical Effects of Novel N -Benzyl-2-Phenylethylamine Derivatives in Adult Zebrafish . ACS Chemical Neuroscience 13:13, pages 1902-1922.
Crossref
Younis Abiedalla, Ahmad J. Almalki, Jack DeRuiter & C. Randall Clark. (2021) GC–MS and GC–IR analysis of substituted N-benzyl 4-bromo-2,5-dimethoxyphenylisopropylamines. Forensic Chemistry 24, pages 100326.
Crossref
Eswaran Prabakaran & Kriveshini Pillay. (2021) Nanomaterials for latent fingerprint detection: a review. Journal of Materials Research and Technology 12, pages 1856-1885.
Crossref
Katarzyna Kamińska, Paweł Świt & Kamilla Malek. (2020) 2-(4-Iodo-2,5-dimethoxyphenyl)- N -[(2-methoxyphenyl)methyl]ethanamine (25I-NBOME): A Harmful Hallucinogen Review . Journal of Analytical Toxicology 44:9, pages 947-956.
Crossref
Veronica Cocchi, Sofia Gasperini, Patrizia Hrelia, Micaela Tirri, Matteo Marti & Monia Lenzi. (2020) Novel Psychoactive Phenethylamines: Impact on Genetic Material. International Journal of Molecular Sciences 21:24, pages 9616.
Crossref
Ahmad J. Almalki, C. Randall Clark, Younis Abiedalla & Jack DeRuiter. (2020) GC–MS analysis of methylenedioxybenzyl analogues of the serotonin receptor agonists 25X-NBOMe drugs. Forensic Chemistry 21, pages 100284.
Crossref
Ahmad J. Almalki, C. Randall Clark, Younis Abiedalla & Jack DeRuiter. (2020) GC–MS analysis of N-(bromodimethoxybenzyl)-2-, 3-, and 4-methoxyphenethylamines: Inverse analogues of the psychoactive 25B-NBOMe drug. Forensic Chemistry 21, pages 100277.
Crossref
Ahmad J. Almalki, Lewis Smith, Younis Abiedalla, C. Randall Clark & Jack DeRuiter. (2020) Vapor phase infrared identification of regioisomeric N-(dimethoxybenzyl)-4-iodo- and 4-bromo-2,5-dimethoxyphenethylamines. Forensic Chemistry 19, pages 100239.
Crossref
Hadil M. Elbardisy, Eduardo M. Richter, Robert D. Crapnell, Michael P. Down, Peter G. Gough, Tarek S. Belal, Wael Talaat, Hoda G. Daabees & Craig E. Banks. (2020) Versatile additively manufactured (3D printed) wall-jet flow cell for high performance liquid chromatography-amperometric analysis: application to the detection and quantification of new psychoactive substances (NBOMes). Analytical Methods 12:16, pages 2152-2165.
Crossref
Elias Lützen, Michael Holtkamp, Imke Stamme, Robin Schmid, Michael Sperling, Michael Pütz & Uwe Karst. (2020) Multimodal imaging of hallucinogens 25C‐ and 25I‐NBOMe on blotter papers. Drug Testing and Analysis 12:4, pages 465-471.
Crossref
Jolanta B. Zawilska, Monika Kacela & Piotr Adamowicz. (2020) NBOMes–Highly Potent and Toxic Alternatives of LSD. Frontiers in Neuroscience 14.
Crossref
Hadil M. Elbardisy, Christopher W. Foster, Jack Marron, Ryan E. Mewis, Oliver B. Sutcliffe, Tarek S. Belal, Wael Talaat, Hoda G. Daabees & Craig E. Banks. (2019) Quick Test for Determination of N-Bombs (Phenethylamine Derivatives, NBOMe) Using High-Performance Liquid Chromatography: A Comparison between Photodiode Array and Amperometric Detection. ACS Omega 4:11, pages 14439-14450.
Crossref
Camila M. de Almeida, Fernanda E. Pinto, Nayara A. dos Santos, Lindamara M. de Souza, Bianca B. Merlo, Christopher J. Thompson & Wanderson Romão. (2019) Designer drugs analysis by LDI(+), MALDI(+) and MALDI(+) imaging coupled to FT-ICR MS. Microchemical Journal 149, pages 104002.
Crossref
Monika Herian, Adam Wojtas, Katarzyna Kamińska, Paweł Świt, Anna Wach & Krystyna Gołembiowska. (2019) Hallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats. Neurotoxicity Research 36:1, pages 91-100.
Crossref
Jun Sang Yu, Hyewon Seo, Gi Beom Kim, Jin Hong & Hye Hyun Yoo. (2019) MS-Based Molecular Networking of Designer Drugs as an Approach for the Detection of Unknown Derivatives for Forensic and Doping Applications: A Case of NBOMe Derivatives. Analytical Chemistry 91:9, pages 5483-5488.
Crossref
Ana Maria dos Santos Moreira, Hanna Leijoto de Oliveira, João Francisco Allochio Filho, Diego Hernando Ângulo Florez, Marcela Matos Cordeiro Borges, Valdemar LacerdaJr.Jr., Wanderson Romão & Keyller Bastos Borges. (2019) NBOMe compounds: An overview about analytical methodologies aiming their determination in biological matrices. TrAC Trends in Analytical Chemistry 114, pages 260-277.
Crossref
George Sam Wang & Christopher Hoyte. (2019) Novel Drugs of Abuse. Pediatrics In Review 40:2, pages 71-78.
Crossref
S. S. Barsegyan, A. N. Kiryushin, N. N. Eroshchenko, N. O. Tuaeva, A. E. Nosyrev & A. A. Kirilyuk. (2019) The detection of the 25B-NBOMe derivative of phenylethylamine in the biological material. Sudebno-meditsinskaya ekspertiza 62:2, pages 34.
Crossref
Ryan Graddy, Megan E. Buresh & Darius A. Rastegar. (2018) New and Emerging Illicit Psychoactive Substances. Medical Clinics of North America 102:4, pages 697-714.
Crossref
Dino Luethi, Daniel Trachsel, Marius C. Hoener & Matthias E. Liechti. (2018) Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs). Neuropharmacology 134, pages 141-148.
Crossref
María Luisa Soria. (2018) New psychoactive substances: Popular and dangerous. Spanish Journal of Legal Medicine 44:2, pages 64-72.
Crossref
María Luisa Soria. (2018) Las nuevas drogas psicoactivas: populares y peligrosas. Revista Española de Medicina Legal 44:2, pages 64-72.
Crossref
David E. Nichols & Charles S. Grob. (2018) Is LSD toxic?. Forensic Science International 284, pages 141-145.
Crossref
Ahmed Al-Imam. (2018) 25b-NBOMe: A Case Report of Sudden Death and Insightful View of Google Trends Data. Iranian Journal of Psychiatry and Behavioral Sciences 12:1.
Crossref
Lorna A. Nisbet, Rafael Venson, Fiona M. Wylie & Karen S. Scott. (2017) Application of a Urine and Hair Validated LC–MS-MS Method to Determine the Effect of Hair Color on the Incorporation of 25B-NBOMe, 25C-NBOMe and 25I-NBOMe into Hair in the Rat. Journal of Analytical Toxicology 41:6, pages 559-565.
Crossref
Daniel Martins, Monica J. Barratt, Cristiana Vale Pires, Helena Carvalho, Mireia Ventura Vilamala, Iván Fornís Espinosa & Helena Valente. (2017) The detection and prevention of unintentional consumption of DOx and 25x-NBOMe at Portugal's Boom Festival. Human Psychopharmacology: Clinical and Experimental 32:3, pages e2608.
Crossref
Ariane Wohlfarth, Markus Roman, Mikael Andersson, Fredrik C. Kugelberg, Xingxing Diao, Jeremy Carlier, Caroline Eriksson, Xiongyu Wu, Peter Konradsson, Martin Josefsson, Marilyn A. Huestis & Robert Kronstrand. (2017) 25C-NBOMe and 25I-NBOMe metabolite studies in human hepatocytes, in vivo mouse and human urine with high-resolution mass spectrometry . Drug Testing and Analysis 9:5, pages 680-698.
Crossref
David E. Nichols. 2018. Behavioral Neurobiology of Psychedelic Drugs. Behavioral Neurobiology of Psychedelic Drugs 1 43 .
Sabra Botch-Jones, Jamie Foss, David Barajas, Frank Kero, Craig Young & Jason Weisenseel. (2016) The detection of NBOMe designer drugs on blotter paper by high resolution time-of-flight mass spectrometry (TOFMS) with and without chromatography. Forensic Science International 267, pages 89-95.
Crossref
Toshiaki Murai & Natsumi Mutoh. (2016) Sequential Addition Reaction of Sulfanylmethyllithiums and Grignard Reagents to Thioformamides Leading to the Formation of 2-Phenyl-2-sulfanylethyl Tertiary Amines. The Journal of Organic Chemistry 81:18, pages 8131-8134.
Crossref
David E. Nichols. (2016) Psychedelics. Pharmacological Reviews 68:2, pages 264-355.
Crossref
Jolanta B. Zawilska & Dariusz Andrzejczak. (2015) Next generation of novel psychoactive substances on the horizon – A complex problem to face. Drug and Alcohol Dependence 157, pages 1-17.
Crossref
Justin L. Poklis, Stephen A. Raso, Kylie N. Alford, Alphonse Poklis & Michelle R. Peace. (2015) Analysis of 25I-NBOMe, 25B-NBOMe, 25C-NBOMe and Other Dimethoxyphenyl- N -[(2-Methoxyphenyl) Methyl]Ethanamine Derivatives on Blotter Paper . Journal of Analytical Toxicology 39:8, pages 617-623.
Crossref
David E. Nichols, M. Flori Sassano, Adam L. Halberstadt, Landon M. Klein, Simon D. BrandtSimon P. ElliottWolfgang J. Fiedler. (2015) N -Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT 2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues . ACS Chemical Neuroscience 6:7, pages 1165-1175.
Crossref
Mette Findal Andreasen, Rasmus Telving, Ingrid Rosendal, Marlene Beyer Eg, Jørgen Bo Hasselstrøm & Ljubica Vukelic Andersen. (2015) A fatal poisoning involving 25C-NBOMe. Forensic Science International 251, pages e1-e8.
Crossref
Yoshie Umemura, Thomas A. Andrew, Valerie L. Jacobs, Andrew J. Giustini, Lionel D. Lewis & James J. Filiano. (2015) Fatal 25I-NBOMe Intoxication: A New Recreational Risk. Academic Forensic Pathology 5:1, pages 91-97.
Crossref
William E. Fantegrossi, Bradley W. Gray, Jessica M. Bailey, Douglas A. Smith, Martin Hansen & Jesper L. Kristensen. (2014) Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH), a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT2A receptors, in mice. Psychopharmacology 232:6, pages 1039-1047.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.