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Drug and Chemical Toxicology Volume 38, 2015 - Issue 4
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Research Article

Exposure to 2,5-hexanedione is accompanied by ovarian and uterine oxidative stress and disruption of endocrine balance in rats

Amos O. AbolajiDrug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
,
Isaac A. AdedaraDrug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
,
Adedamola SoladogunDrug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
,
Veronica SalauDrug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
,
Maureen OguakaDrug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria
&
Ebenezer O. FarombiDrug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, NigeriaCorrespondence[email protected] [email protected]
Pages 400-407 | Received 01 May 2014, Accepted 05 Oct 2014, Published online: 12 Nov 2014

Citations (9)

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Isaac A. Adedara, Amos O. Abolaji, Blessing E. Odion, Abiola A. Omoloja, Isioma J. Okwudi & Ebenezer O. Farombi. (2016) Redox status of the testes and sperm of rats following exposure to 2,5-hexanedione. Redox Report 21:6, pages 239-247.
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Articles from other publishers (8)

Xueming Xu, Yimei Pan, Liqin Zhan, Yi Sun, Sichuan Chen, Jianlin Zhu, Lingfeng Luo, Wenchang Zhang & Yuchen Li. (2023) The Wnt/β-catenin pathway is involved in 2,5-hexanedione-induced ovarian granulosa cell cycle arrest. Ecotoxicology and Environmental Safety 268, pages 115720.
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Yi Sun, Huiting Chen, Sichuan Chen, Xueming Xu, Wenchang Zhang & Yuchen Li. (2023) The Hippo signaling pathway contributes to the 2,5-Hexadion-induced apoptosis of ovarian granulosa cells. Journal of Ovarian Research 16:1.
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Ombéline Claux, Vincent Rapinel, Maryline Abert-Vian & Farid Chemat. 2023. Sustainable Food Science - A Comprehensive Approach. Sustainable Food Science - A Comprehensive Approach 271 283 .
Rosaria Cozzolino, Beatrice De Giulio, A Martignetti, G Forte, M Dallio, M Romeo, F Scognamiglio, L Ventriglia, M Stocchero & A Federico. (2022) Urinary volatile Organic compounds in non-alcoholic fatty liver disease (NAFLD), type two diabetes mellitus (T2DM) and NAFLD-T2DM coexistence. Metabolomics 18:12.
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Christian Cravotto, Anne-Sylvie Fabiano-Tixier, Ombéline Claux, Maryline Abert-Vian, Silvia Tabasso, Giancarlo Cravotto & Farid Chemat. (2022) Towards Substitution of Hexane as Extraction Solvent of Food Products and Ingredients with No Regrets. Foods 11:21, pages 3412.
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Ombéline Claux, Vincent Rapinel, Pascale Goupy, Norbert Patouillard, Maryline Abert Vian, Laurence Jacques & Farid Chemat. (2021) Dry and Aqueous 2-Methyloxolane as Green Solvents for Simultaneous Production of Soybean Oil and Defatted Meal. ACS Sustainable Chemistry & Engineering 9:21, pages 7211-7223.
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Jingwen Zeng, Yan Sun, Xiaoqin Li, Jianlin Zhu, Wenchang Zhang, Wenmin Lu, Yuyao Weng & Jin Liu. (2020) 2,5-Hexanedione influences primordial follicular development in cultured neonatal mouse ovaries by interfering with the PI3K signaling pathway via miR-214-3p. Toxicology and Applied Pharmacology 409, pages 115335.
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Amos O. Abolaji, Isaac A. Adedara, Ayodeji O. Abajingin, Ore J. Fatunmibi, Emmanuel O. Ladipo & Ebenezer O. Farombi. (2016) Evidence of oxidative damage and reproductive dysfunction accompanying 4-vinylcyclohexene diepoxide exposure in female Wistar rats. Reproductive Toxicology 66, pages 10-19.
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