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Research Article

Evaluation of Acetaminophen-Induced Developmental Toxicity Using Fetax

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Pages 329-350 | Published online: 27 Sep 2008

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Read on this site (6)

Min Ok Song, Douglas J. Fort, Daniel L. McLaughlin, Robert L. Rogers, John H. Thomas, Brody O. Buzzard, Andra M. Noll & Natalie K. Myers. (2003) Evaluation of Xenopus tropicalis as an Alternative Test Organism for Frog Embryo Teratogenesis Assay—Xenopus (FETAX). Drug and Chemical Toxicology 26:3, pages 177-189.
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Douglas J. Fort, Daniel W. McLaughlin, Robert L. Rogers & Brody O. Buzzard. (2003) Evaluation of the Developmental Toxicities of Ethanol, Acetaldehyde, and Thioacetamide Using FETAX. Drug and Chemical Toxicology 26:1, pages 23-34.
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Douglas J. Fort, Robert L. Rogers, Robbin R. Paul, Enos L. Stover & Robert A. Finch. (2001) OPTIMIZATION OF AN EXOGENOUS METABOLIC ACTIVATION SYSTEM FOR FETAX. II. PRELIMINARY EVALUATION. Drug and Chemical Toxicology 24:2, pages 117-127.
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Douglas J. Fort, Enos L. Stover, Timothy Propst, Mendi A. Hull & John A. Bantle. (1998) Evaluation of the Developmental Toxicities of Coumarin, 4-Hydroxycoumarin, and 7-Hydroxycoumarin Using Fetax. Drug and Chemical Toxicology 21:1, pages 15-26.
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Douglas J. Fort, Enos L. Stover, John A. Bantle, James R. Rayburn, Mendi A. Hull, Robert A. Finch, Dennis T. Burton, Steven D. Turley, Douglas A. Dawson, Greg Linder, David Buchwalter, James N. Dumont, Marie Kumsher-King & Angela M. Gaudet-Hull. (1998) Phase III Interlaboratory Study of Fetax, Part 2: Interlaboratory Validation of an Exogenous Metabolic Activation System for Frog Embryo Teratogenesis Assay-Xenopus (Fetax). Drug and Chemical Toxicology 21:1, pages 1-14.
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JamesG. Burkhart & HenryS. Gardner. (1997) Non‐mammalian and environmental sentinels in human health: “Back to the future?”;. Human and Ecological Risk Assessment: An International Journal 3:3, pages 309-328.
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Articles from other publishers (26)

Verónica Margarita Gutiérrez-Noya, Leobardo Manuel Gómez-Oliván, María del Carmen Ramírez-Montero, Hariz Islas-Flores, Marcela Galar-Martínez & Sandra García-Medina. (2021) Survival and malformations rates, oxidative status in early life stages of Cyprinus carpio due to exposure to environmentally realistic concentrations of paracetamol. Science of The Total Environment 768, pages 144585.
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Itzayana Pérez-Alvarez, Hariz Islas-Flores, Leobardo Manuel Gómez-Oliván & Octavio Dublán García. 2020. Non-Steroidal Anti-Inflammatory Drugs in Water. Non-Steroidal Anti-Inflammatory Drugs in Water 115 129 .
Hariz Islas-Flores, Itzayana Pérez-Alvarez, Leobardo Manuel Gómez-Oliván & Nely San Juan-Reyes. 2019. Pollution of Water Bodies in Latin America. Pollution of Water Bodies in Latin America 55 66 .
Jesús Daniel Cardoso-Vera, Hariz Islas-Flores, Nely SanJuan-Reyes, Elena Irabella Montero-Castro, Marcela Galar-Martínez, Sandra García-Medina, Armando Elizalde-Velázquez, Octavio Dublán-García & Leobardo Manuel Gómez-Oliván. (2017) Comparative study of diclofenac-induced embryotoxicity and teratogenesis in Xenopus laevis and Lithobates catesbeianus, using the frog embryo teratogenesis assay: Xenopus (FETAX). Science of The Total Environment 574, pages 467-475.
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Kelly G. Sullivan & Michael Levin. (2016) Neurotransmitter signaling pathways required for normal development in Xenopus laevis embryos: a pharmacological survey screen . Journal of Anatomy 229:4, pages 483-502.
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Isabelle Leconte & Isabelle Mouche. 2013. Teratogenicity Testing. Teratogenicity Testing 403 421 .
Hsi-Chu Peng, Yun-Hsin Wang, Chi-Chung Wen, Wei-Hua Wang, Chien-Chung Cheng & Yau-Hung Chen. (2010) Nephrotoxicity assessments of acetaminophen during zebrafish embryogenesis. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 151:4, pages 480-486.
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Geoffrey R Smith & Amber A Burgett. (2005) Effects of Three Organic Wastewater Contaminants on American Toad, Bufo americanus, Tadpoles. Ecotoxicology 14:4, pages 477-482.
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Douglas Fort & Robert Rogers. 2005. Techniques in Aquatic Toxicology, Volume 2. Techniques in Aquatic Toxicology, Volume 2.
Douglas J. Fort, Robert L. Rogers, John H. Thomas, Brody O. Buzzard, Andra M. Noll & Clinton D. Spaulding. (2004) Comparative sensitivity of Xenopus tropicalis and Xenopus laevis as test species for the FETAX model . Journal of Applied Toxicology 24:6, pages 443-457.
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Douglas J. Fort & Robbin R. Paul. (2002) Enhancing the predictive validity of Frog Embryo Teratogenesis Assay— Xenopus (FETAX) . Journal of Applied Toxicology 22:3, pages 185-191.
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Mariangela Prati, Elia Biganzoli, Patrizia Boracchi, Marina Tesauro, Claudio Monetti & Giovanni Bernardini. (2000) Ecotoxicological soil evaluation by FETAX. Chemosphere 41:10, pages 1621-1628.
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Douglas J. Fort, Robert L. Rogers, Lisa A. Morgan, Mark F. Miller, Patrick A. Clark, Julia A. White, Robbin R. Paul & Enos L. Stover. (2000) preliminary validation of a short-term morphological assay to evaluate adverse effects on amphibian metamorphosis and thyroid function usingxenopus laevis. Journal of Applied Toxicology 20:5, pages 419-425.
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Douglas J. Fort, Enos L. Stover, Donna R. Farmer & Joan K. Lemen. (2000) Assessing the predictive validity of frog embryo teratogenesis assay?Xenopus (FETAX). Teratogenesis, Carcinogenesis, and Mutagenesis 20:2, pages 87-98.
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Douglas J. Fort, Enos L. Stover, John A. Bantle & Robert A. Finch. (2000) Evaluation of the developmental toxicity of thalidomide using frog embryo teratogenesis assay?Xenopus (FETAX): biotransformation and detoxification. Teratogenesis, Carcinogenesis, and Mutagenesis 20:1, pages 35-47.
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Douglas J. Fort, Robert Rogers, Holly Copley, Lizbeth Bruning, Enos L. Stover & Dave Rapaport. (1999) Effect of sulfometuron methyl and nicosulfuron on development and metamorphosis in Xenopus laevis : Impact of purity . Environmental Toxicology and Chemistry 18:12, pages 2934-2940.
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Douglas J. Fort, Enos L. Stover, Philip L. Strong, F.Jay Murray & Carl L. Keen. (1999) Chronic Feeding of a Low Boron Diet Adversely Affects Reproduction and Development in Xenopus laevis. The Journal of Nutrition 129:11, pages 2055-2060.
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John A. Bantle, Robert A. Finch, Douglas J. Fort, Enos L. Stover, Mendi Hull, Marie Kumsher-King & Angela M. Gaudet-Hull. (1999) Phase III interlaboratory study of FETAX part 3. FETAX validation using 12 compounds with and without an exogenous metabolic activation system. Journal of Applied Toxicology 19:6, pages 447-472.
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Douglas J. Fort, Timothy L. Propst, Enos L. Stover, Judy C. Helgen, Rick B. Levey, Kathryn Gallagher & James G. Burkhart. (1999) Effects of pond water, sediment, and sediment extracts from minnesota and vermont, USA, on early development and metamorphosis of xenopus. Environmental Toxicology and Chemistry 18:10, pages 2305-2315.
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Douglas J. Fort, Enos L. Stover, Philip L. Strong & F. Jay Murray. (1999) Effect of boron deprivation on reproductive parameters inXenopus laevis. The Journal of Trace Elements in Experimental Medicine 12:3, pages 187-204.
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Douglas J. Fort, Timothy L. Propst, Enos L. Stover, F. Jay Murray & Philip L. Strong. (1999) Adverse effects from low dietary and environmental boron exposure on reproduction, development, and maturation inXenopus laevis. The Journal of Trace Elements in Experimental Medicine 12:3, pages 175-185.
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Douglas J. Fort, Timothy L. Propst, Enos L. Stover, Philip L. Strong & F. Jay Murray. (2013) Adverse reproductive and developmental effects inXenopus from insufficient boron. Biological Trace Element Research 66:1-3, pages 237-259.
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D.J. Fort, E.L. Stover, T.L. Propst, B.C. Faulkner, T.A. Vollmuth & F.J. Murray. (1998) Evaluation of the Developmental Toxicity of Caffeine and Caffeine Metabolites using the Frog Embryo Teratogenesis Assay—Xenopus (FETAX). Food and Chemical Toxicology 36:7, pages 591-600.
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James J. La Clair, John A. Bantle & James Dumont. (1998) Photoproducts and Metabolites of a Common Insect Growth Regulator Produce Developmental Deformities in Xenopus . Environmental Science & Technology 32:10, pages 1453-1461.
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John A. Bantle, James R. Rayburn, Dennis T. Burton, Steven D. Turley, Douglas A. Dawson, James N. Dumont, Robert A. Finch, Margaret A. Maurice, Douglas J. Fort, Greg Linder & David Buchwalter. (2006) Initial interlaboratory validation study of FETAX: Phase I testing. Journal of Applied Toxicology 14:3, pages 213-223.
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Douglas J. Fort, Enos L. Stover, James R. Rayburn, Mendi Hull & John A. Bantle. (2005) Evaluation of the developmental toxicity of trichloroethylene and detoxification metabolites using Xenopus . Teratogenesis, Carcinogenesis, and Mutagenesis 13:1, pages 35-45.
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