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Original Article

A Congenital Heart Defect in Drosophila Caused by an Action-Potential Mutation

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Pages 153-168 | Received 13 Oct 1994, Published online: 11 Jul 2009

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Erik Johnson, John Ringo, Nancy Bray & Harold Dowse. (1998) Genetic and Pharmacological Identification of Ion Channels Central to the Drosophila Cardiac Pacemaker. Journal of Neurogenetics 12:1, pages 1-24.
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Candace Kerr, John Ringo, Harold Dowse & Erik Johnson. (1997) Icebox, a Recessive X-Linked Mutation in Drosophila Causing Low Sexual Receptivity. Journal of Neurogenetics 11:3-4, pages 213-229.
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Articles from other publishers (45)

Nicole Hensley, Elizabeth R. Elliott, Maya O. Abul-Khoudoud & Robin L. Cooper. (2023) Effect of 2-Aminoethoxydiphenyl Borate (2-APB) on Heart Rate and Relation with Suppressed Calcium-Activated Potassium Channels: Larval Drosophila Model. Applied Biosciences 2:2, pages 236-248.
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Clara de Castro, Josh Titlow, Zana R. Majeed, Cole Malloy, Kayla E. King & Robin L. Cooper. (2019) Mechanical and Chemical Factors Required for Maintaining Cardiac Rhythm in Drosophila melanogaster Larva. Journal of Entomology 16:2, pages 62-73.
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Worawan B. Limpitikul, Meera C. Viswanathan, Brian O'Rourke, David T. Yue & Anthony Cammarato. (2018) Conservation of cardiac L-type Ca2+ channels and their regulation in Drosophila: A novel genetically-pliable channelopathic model. Journal of Molecular and Cellular Cardiology 119, pages 64-74.
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Cole Malloy, Jacob Sifers, Angela Mikos, Aya Samadi, Aya Omar, Christina Hermanns & Robin L. Cooper. (2017) Using optogenetics to assess neuroendocrine modulation of heart rate in Drosophila melanogaster larvae. Journal of Comparative Physiology A 203:10, pages 791-806.
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Karen Ocorr, Alexander Zambon, Yoav Nudell, Santiago Pineda, Soda Diop, Min Tang, Takeshi Akasaka & Erika Taylor. (2017) Age-dependent electrical and morphological remodeling of the Drosophila heart caused by hERG/seizure mutations. PLOS Genetics 13:5, pages e1006786.
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Silja Burkhard, Vincent van Eif, Laurence Garric, Vincent Christoffels & Jeroen Bakkers. (2017) On the Evolution of the Cardiac Pacemaker. Journal of Cardiovascular Development and Disease 4:2, pages 4.
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R. Bodmer, R.J. Wessells, A. Sujkowski, E. Johnson, V. Beasley & H. Dowse. 2017. Reference Module in Life Sciences. Reference Module in Life Sciences.
Tricia VanKirk, Evelyn Powers & Harold B. Dowse. (2016) Melatonin increases the regularity of cardiac rhythmicity in the Drosophila heart in both wild-type and strains bearing pathogenic mutations. Journal of Comparative Physiology B 187:1, pages 63-78.
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Vernon Beasley & Harold Dowse. (2016) Suppression of Tryptophan 2,3-Dioxygenase Produces a Slow Heartbeat Phenotype in Drosophila melanogaster . Journal of Experimental Zoology Part A: Ecological Genetics and Physiology 325:10, pages 651-664.
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Yue Chen Zhu, Emily Yocom, Jacob Sifers, Henry Uradu & Robin L. Cooper. (2016) Modulatory effects on Drosophila larva hearts: room temperature, acute and chronic cold stress. Journal of Comparative Physiology B 186:7, pages 829-841.
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Ouarda Taghli-Lamallem, Emilie Plantié & Krzysztof Jagla. (2016) Drosophila in the Heart of Understanding Cardiac Diseases: Modeling Channelopathies and Cardiomyopathies in the Fruitfly. Journal of Cardiovascular Development and Disease 3:1, pages 7.
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Dao-Fu Dai, Ying-Ann Chiao, Robert J. Wessells, Rolf Bodmer, Hazel H. Szeto & Peter S. Rabinovitch. 2016. Handbook of the Biology of Aging. Handbook of the Biology of Aging 459 494 .
Cole A. Malloy, Kyle Ritter, Jonathan Robinson, Connor English & Robin L. Cooper. (2015) Pharmacological identification of cholinergic receptor subtypes on Drosophila melanogaster larval heart. Journal of Comparative Physiology B 186:1, pages 45-57.
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Simina Bogatan, Duygu Cevik, Valentin Demidov, Jessica Vanderploeg, Abdullah Panchbhaya, Alex Vitkin & J. Roger Jacobs. (2015) Talin Is Required Continuously for Cardiomyocyte Remodeling during Heart Growth in Drosophila. PLOS ONE 10:6, pages e0131238.
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Jonas Lembcke Andersen, Heath Andrew MacMillan & Johannes Overgaard. (2015) Temperate Drosophila preserve cardiac function at low temperature. Journal of Insect Physiology 77, pages 26-32.
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Karen Ocorr, Georg Vogler & Rolf Bodmer. (2014) Methods to assess Drosophila heart development, function and aging. Methods 68:1, pages 265-272.
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Harold B Dowse. (2013) Maximum entropy spectral analysis for circadian rhythms: theory, history and practice. Journal of Circadian Rhythms 11:0, pages 6.
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Nicole Piazza & R.J. Wessells. 2011. Animal Models of Human Disease. Animal Models of Human Disease 155 210 .
Rolf Bodmer & Manfred Frasch. 2010. Heart Development and Regeneration. Heart Development and Regeneration 47 86 .
Dao-Fu Dai, Robert J. Wessells, Rolf Bodmer & Peter S. Rabinovitch. 2010. The Comparative Biology of Aging. The Comparative Biology of Aging 259 286 .
Tricia Jennings, John Ringo & Harold Dowse. (2009) The relationship of heart function to temperature in Drosophila melanogaster and its heritability . Journal of Experimental Zoology Part A: Ecological Genetics and Physiology 311A:9, pages 689-696.
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L. Qian & R. Bodmer. (2009) Partial loss of GATA factor Pannier impairs adult heart function in Drosophila. Human Molecular Genetics 18:17, pages 3153-3163.
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Martin Fink, Carles Callol-Massot, Angela Chu, Pilar Ruiz-Lozano, Juan Carlos Izpisua Belmonte, Wayne Giles, Rolf Bodmer & Karen Ocorr. (2009) A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. BioTechniques 46:2, pages 101-113.
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Harold B. Dowse. 2009. Computer Methods, Part A. Computer Methods, Part A 141 174 .
Ouarda Taghli-Lamallem, Rolf Bodmer, Jeffrey S. Chamberlain & Anthony Cammarato. (2008) Genetics and pathogenic mechanisms of cardiomyopathies in the Drosophila model. Drug Discovery Today: Disease Models 5:3, pages 125-134.
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Marc J. Klowden. 2008. Physiological Systems in Insects. Physiological Systems in Insects 357 401 .
Li Qian, Jiandong Liu & Rolf Bodmer. 2007. Cardiovascular Development. Cardiovascular Development 1 29 .
Harold B. Dowse. 2007. Circadian Rhythms. Circadian Rhythms 29 45 .
Sameera Dasari & Robin L. Cooper. (2005) Direct influence of serotonin on the larval heart of Drosophila melanogaster. Journal of Comparative Physiology B 176:4, pages 349-357.
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Andrew F.M. Johnstone & Robin L. Cooper. (2006) Direct innervation of the Drosophila melanogaster larval aorta. Brain Research 1083:1, pages 159-163.
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Subhabrata Sanyal, Tricia Jennings, Harold Dowse & Mani Ramaswami. (2005) Conditional mutations in SERCA, the Sarco-endoplasmic reticulum Ca2+-ATPase, alter heart rate and rhythmicity in Drosophila. Journal of Comparative Physiology B 176:3, pages 253-263.
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Davide Dulcis, Richard B. Levine & John Ewer. (2005) Role of the neuropeptide CCAP inDrosophila cardiac function. Journal of Neurobiology 64:3, pages 259-274.
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Karel Sláma & Robert Farkaš. (2005) Heartbeat patterns during the postembryonic development of Drosophila melanogaster. Journal of Insect Physiology 51:5, pages 489-503.
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Davide Dulcis & Richard B. Levine. (2005) Glutamatergic Innervation of the Heart Initiates Retrograde Contractions in Adult Drosophila melanogaster . The Journal of Neuroscience 25:2, pages 271-280.
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R. Bodmer, R.J. Wessells, E.C. Johnson & H. Dowse. 2005. Comprehensive Molecular Insect Science. Comprehensive Molecular Insect Science 199 250 .
Robert J Wessells, Erin Fitzgerald, James R Cypser, Marc Tatar & Rolf Bodmer. (2004) Insulin regulation of heart function in aging fruit flies. Nature Genetics 36:12, pages 1275-1281.
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Robert J. Wessells & Rolf Bodmer. (2004) Screening assays for heart function mutants in Drosophila . BioTechniques 37:1, pages 58-66.
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Davide Dulcis & Richard B. Levine. (2003) Innervation of the heart of the adult fruit fly,Drosophila melanogaster. The Journal of Comparative Neurology 465:4, pages 560-578.
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Balaji Krishnan, Joel D. Levine, M. Kathlea S. Lynch, Harold B. Dowse, Pablo Funes, Jeffrey C. Hall, Paul E. Hardin & Stuart E. Dryer. (2001) A new role for cryptochrome in a Drosophila circadian oscillator. Nature 411:6835, pages 313-317.
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Erik Johnson, John Ringo & Harold Dowse. (2001) Dynamin, encoded byshibire, is central to cardiac function. Journal of Experimental Zoology 289:2, pages 81-89.
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CHRISOVALANTIS PAPAEFTHIMIOU & GEORGE THEOPHILIDIS. (2001) AN IN VITRO METHOD FOR RECORDING THE ELECTRICAL ACTIVITY OF THE ISOLATED HEART OF THE ADULT DROSOPHILA MELANOGASTER. In Vitro Cellular & Developmental Biology - Animal 37:7, pages 445.
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Erik Johnson, John Ringo & Harold Dowse. (2000) Native and heterologous neuropeptides are cardioactive in Drosophila melanogaster. Journal of Insect Physiology 46:8, pages 1229-1236.
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N.J. Curtis, J.M. Ringo & H.B. Dowse. (1999) Morphology of the pupal heart, adult heart, and associated tissues in the fruit fly,Drosophila melanogaster. Journal of Morphology 240:3, pages 225-235.
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