351
Views
50
CrossRef citations to date
0
Altmetric
Research Article

Apocynin reduces reactive oxygen species concentrations in exhaled breath condensate in asthmatics

, , , , , , & show all
Pages 90-99 | Received 26 Mar 2011, Accepted 12 Dec 2011, Published online: 01 Feb 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Yaru Ju, Yan Feng, Xiaolin Hou, Lixia Wu, Huixia Yang, Hongjuan Zhang & Yan’Na Ma. (2022) Combined apocyanin and aspirin treatment activates the PI3K/Nrf2/HO-1 signaling pathway and ameliorates preeclampsia symptoms in rats. Hypertension in Pregnancy 41:1, pages 39-50.
Read now
Maryam Boshtam, Shirin Kouhpayeh, Farahnaz Amini, Yadollah Azizi, Malihe Najaflu, Laleh Shariati & Hossein Khanahmad. (2021) Anti-inflammatory effects of apocynin: a narrative review of the evidence. All Life 14:1, pages 997-1010.
Read now
Claire Brockwell, Sundari Ampikaipakan, Darren W Sexton, David Price, Daryl Freeman, Mike Thomas, Muzammil Ali & Andrew M Wilson. (2014) Adjunctive treatment with oral AKL1, a botanical nutraceutical, in chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 9, pages 715-721.
Read now
Wolfgang Domej, Karl Oettl & Wilfried Renner. (2014) Oxidative stress and free radicals in COPD – implications and relevance for treatment. International Journal of Chronic Obstructive Pulmonary Disease 9, pages 1207-1224.
Read now

Articles from other publishers (46)

Yea‐Jin Park, Tae‐Young Gil, Bo‐Ram Jin, Yun‐Yeop Cha & Hyo‐Jin An. (2023) Apocynin alleviates weight gain and obesity‐induced adipose tissue inflammation in high‐fat diet‐fed C57BL /6 mice . Phytotherapy Research 37:8, pages 3481-3494.
Crossref
Wenxing Hu, Serene M. L. Lee, Alexandr V. Bazhin, Markus Guba, Jens Werner & Hanno Nieß. (2022) Neutrophil extracellular traps facilitate cancer metastasis: cellular mechanisms and therapeutic strategies. Journal of Cancer Research and Clinical Oncology 149:5, pages 2191-2210.
Crossref
Paulina Kleniewska & Rafał Pawliczak. (2022) Does Oxidative Stress Along with Dysbiosis Participate in the Pathogenesis of Asthma in the Obese?. Cell Biochemistry and Biophysics 81:1, pages 117-126.
Crossref
Frank Silva Bezerra, Manuella Lanzetti, Renata Tiscoski Nesi, Akinori Cardozo Nagato, Cyntia Pecli e Silva, Emanuel Kennedy-Feitosa, Adriana Correa Melo, Isabella Cattani-Cavalieri, Luís Cristóvão Porto & Samuel Santos Valenca. (2023) Oxidative Stress and Inflammation in Acute and Chronic Lung Injuries. Antioxidants 12:3, pages 548.
Crossref
Dania Kattan, Chloe Barsa, Sarin Mekhijian, Zaynab Shakkour, Maya Jammoul, Mark Doumit, Maria Camila Pareja Zabala, Nadine Darwiche, Ali H. Eid, Yehia Mechref, Kevin K. Wang, Juan Pablo de Rivero Vaccari, Jennifer C. Munoz Pareja & Firas Kobeissy. (2023) Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview. Neuroscience & Biobehavioral Reviews 144, pages 104969.
Crossref
Vichuda Charoensaensuk, Yen-Chou Chen, Yun-Ho Lin, Keng-Liang Ou, Liang-Yo Yang & Dah-Yuu Lu. (2022) 2,3,5,4′-Tetrahydroxystilbene-2-O-β-glucoside Attenuates Reactive Oxygen Species-Dependent Inflammation and Apoptosis in Porphyromonas gingivalis-Infected Brain Endothelial Cells. Antioxidants 11:4, pages 740.
Crossref
Ramazan Ozdemir, Ismail Kursat Gokce, Suat Tekin, Asli Cetin Taslidere, Hatice Turgut, Kevser Tanbek, Cemile Ceren Gul, Mehmet Fatih Deveci & Mehmet Aslan. (2021) The protective effects of apocynin in hyperoxic lung injury in neonatal rats. Pediatric Pulmonology 57:1, pages 109-121.
Crossref
Maximillian Taro William Lee, William Mahy & Mark David Rackham. (2021) The medicinal chemistry of mitochondrial dysfunction: a critical overview of efforts to modulate mitochondrial health. RSC Medicinal Chemistry 12:8, pages 1281-1311.
Crossref
Alexander A. Tokmakov & Ken-Ichi Sato. (2021) Modulation of Intracellular ROS and Senescence-Associated Phenotypes of Xenopus Oocytes and Eggs by Selective Antioxidants. Antioxidants 10:7, pages 1068.
Crossref
Meghan C. Gage & Thimmasettappa Thippeswamy. (2021) Inhibitors of Src Family Kinases, Inducible Nitric Oxide Synthase, and NADPH Oxidase as Potential CNS Drug Targets for Neurological Diseases. CNS Drugs 35:1, pages 1-20.
Crossref
Han Sha, Yanchao Ma, Yuli Tong, Jie Zhao & Fengzhi Qin. (2020) Apocynin inhibits placental TLR4/NF-κB signaling pathway and ameliorates preeclampsia-like symptoms in rats. Pregnancy Hypertension 22, pages 210-215.
Crossref
Yannick Mathieu, Juan D. Vidal, Lourdes Arribas Martínez, Nerea Abad Fernández, Sara Iborra & Avelino Corma. (2020) Molecular Oxygen Lignin Depolymerization: An Insight into the Stability of Phenolic Monomers. ChemSusChem 13:17, pages 4743-4758.
Crossref
Joanna Wieczfinska, Przemyslaw Sitarek, Tomasz Kowalczyk, Ewa Skała & Rafal Pawliczak. (2020) The Anti-inflammatory Potential of Selected Plant-derived Compounds in Respiratory Diseases. Current Pharmaceutical Design 26:24, pages 2876-2884.
Crossref
Kosuke Kato & Louise Hecker. (2020) NADPH oxidases: Pathophysiology and therapeutic potential in age-associated pulmonary fibrosis. Redox Biology 33, pages 101541.
Crossref
Joanna Wieczfinska, Przemyslaw Sitarek, Ewa Skała, Tomasz Kowalczyk & Rafal Pawliczak. (2019) Inhibition of NADPH Oxidase-Derived Reactive Oxygen Species Decreases Expression of Inflammatory Cytokines in A549 Cells. Inflammation 42:6, pages 2205-2214.
Crossref
Milena Sokolowska, Valerie F. J. Quesniaux, Cezmi A. Akdis, Kian Fan Chung, Bernhard Ryffel & Dieudonnée Togbe. (2019) Acute Respiratory Barrier Disruption by Ozone Exposure in Mice. Frontiers in Immunology 10.
Crossref
Filipa M. Casimiro, Carina A. E. Costa, Cidália M. Botelho, Maria F. Barreiro & Alírio E. Rodrigues. (2019) Kinetics of Oxidative Degradation of Lignin-Based Phenolic Compounds in Batch Reactor. Industrial & Engineering Chemistry Research 58:36, pages 16442-16449.
Crossref
Fiona Augsburger, Aleksandra Filippova, Delphine Rasti, Tamara Seredenina, Magdalena Lam, Ghassan Maghzal, Zahia Mahiout, Pidder Jansen-Dürr, Ulla G. Knaus, James Doroshow, Roland Stocker, Karl-Heinz Krause & Vincent Jaquet. (2019) Pharmacological characterization of the seven human NOX isoforms and their inhibitors. Redox Biology 26, pages 101272.
Crossref
Young-Jae Hwang, Seung-Joo Nam, Wanjoo Chun, Song In Kim, Sung Chul Park, Chang Don Kang & Sung Joon Lee. (2019) Anti-inflammatory effects of apocynin on dextran sulfate sodium-induced mouse colitis model. PLOS ONE 14:5, pages e0217642.
Crossref
Ibon Eguiluz-Gracia, Tunn Ren Tay, Mark Hew, Maria M. Escribese, Domingo Barber, Robyn E. O'Hehir & Maria J. Torres. (2018) Recent developments and highlights in biomarkers in allergic diseases and asthma. Allergy 73:12, pages 2290-2305.
Crossref
Ahmed Ismaeel, Robert Brumberg, Jeffrey Kirk, Evlampia Papoutsi, Patrick Farmer, William Bohannon, Robert Smith, Jack Eidson, Ian Sawicki & Panagiotis Koutakis. (2018) Oxidative Stress and Arterial Dysfunction in Peripheral Artery Disease. Antioxidants 7:10, pages 145.
Crossref
Raghavendar Chandran, TaeHee Kim, Suresh L Mehta, Eshwar Udho, Vishal Chanana, Pelin Cengiz, HwuiWon Kim, Chanul Kim & Raghu Vemuganti. (2017) A combination antioxidant therapy to inhibit NOX2 and activate Nrf2 decreases secondary brain damage and improves functional recovery after traumatic brain injury. Journal of Cerebral Blood Flow & Metabolism 38:10, pages 1818-1827.
Crossref
Elaheh Rahimpour, Maryam Khoubnasabjafari, Vahid Jouyban-Gharamaleki & Abolghasem Jouyban. (2018) Non-volatile compounds in exhaled breath condensate: review of methodological aspects. Analytical and Bioanalytical Chemistry 410:25, pages 6411-6440.
Crossref
Merry W. Ma, Jing Wang, Krishnan M. Dhandapani, Ruimin Wang & Darrell W. Brann. (2018) NADPH oxidases in traumatic brain injury – Promising therapeutic targets?. Redox Biology 16, pages 285-293.
Crossref
Neil C Thomson. (2018) Targeting oxidant-dependent mechanisms for the treatment of respiratory diseases and their comorbidities. Current Opinion in Pharmacology 40, pages 1-8.
Crossref
Merry W. Ma, Jing Wang, Quanguang Zhang, Ruimin Wang, Krishnan M. Dhandapani, Ratna K. Vadlamudi & Darrell W. Brann. (2017) NADPH oxidase in brain injury and neurodegenerative disorders. Molecular Neurodegeneration 12:1.
Crossref
Francesco VioliLorenzo LoffredoRoberto CarnevalePasquale PignatelliDaniele Pastori. (2017) Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly. Antioxidants & Redox Signaling 27:14, pages 1083-1124.
Crossref
Jong Youl Kim, Joohyun Park, Jong Eun Lee & Midori A. Yenari. (2017) NOX Inhibitors - A Promising Avenue for Ischemic Stroke. Experimental Neurobiology 26:4, pages 195-205.
Crossref
Joanna Wieczfinska & Rafal Pawliczak. (2017) Thymic stromal lymphopoietin and apocynin alter the expression of airway remodeling factors in human rhinovirus-infected cells. Immunobiology 222:8-9, pages 892-899.
Crossref
Bo Hu, Yuhong Wu, Fei Tong, Jie Liu, Xiaohua Shen, Ruilin Shen & Guangtao Xu. (2016) Apocynin Alleviates Renal Ischemia/Reperfusion Injury Through Regulating the Level of Zinc and Metallothionen. Biological Trace Element Research 178:1, pages 71-78.
Crossref
Merry W. Ma, Jing Wang, Krishnan M. Dhandapani & Darrell W. Brann. (2017) NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury. Oxidative Medicine and Cellular Longevity 2017, pages 1-18.
Crossref
Tessa Horemans, Gaëlle Boulet, Marian van Kerckhoven, Johannes Bogers, Sofie Thys, Chris Vervaet, Anouck Vervaeck, Peter Delputte, Louis Maes & Paul Cos. (2017) In-vivo evaluation of apocynin for prevention of Helicobacter pylori-induced gastric carcinogenesis. European Journal of Cancer Prevention 26:1, pages 10-16.
Crossref
Samantha L. Passey, Michelle J. Hansen, Steven Bozinovski, Christine F. McDonald, Anne E. Holland & Ross Vlahos. (2016) Emerging therapies for the treatment of skeletal muscle wasting in chronic obstructive pulmonary disease. Pharmacology & Therapeutics 166, pages 56-70.
Crossref
Keer Sun, Vijaya Kumar Yajjala, Christopher Bauer, Geoffrey A. Talmon, Karl J. Fischer, Tammy Kielian & Dennis W. Metzger. (2016) Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia . Journal of Experimental Medicine 213:9, pages 1851-1864.
Crossref
Ahmed Nadeem, Ahmed El-Sherbeeny, Mohammed Al-Harbi & Sheikh Ahmad. 2016. Reactive Oxygen Species in Biology and Human Health. Reactive Oxygen Species in Biology and Human Health 189 203 .
Sheena Francis, Nicola Laurieri, Chukwuemeka Nwokocha & Rupika Delgoda. (2016) Treatment of Rats with Apocynin Has Considerable Inhibitory Effects on Arylamine N-Acetyltransferase Activity in the Liver. Scientific Reports 6:1.
Crossref
L. C. Oostwoud, P. Gunasinghe, H. J. Seow, J. M. Ye, S. Selemidis, S. Bozinovski & R. Vlahos. (2016) Apocynin and ebselen reduce influenza A virus-induced lung inflammation in cigarette smoke-exposed mice. Scientific Reports 6:1.
Crossref
Becky A. DieboldSusan M.E. SmithYang LiJ. David Lambeth. (2015) NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress. Antioxidants & Redox Signaling 23:5, pages 375-405.
Crossref
Joanna WieczfinskaMilena SokolowskaRafal Pawliczak. (2015) NOX Modifiers—Just a Step Away from Application in the Therapy of Airway Inflammation?. Antioxidants & Redox Signaling 23:5, pages 428-445.
Crossref
Talat Kilic, Hakan Parlakpinar, Elif Taslidere, Sedat Yildiz, Alaadin Polat, Nigar Vardi, Cemil Colak & Hilal Ermis. (2014) Protective and Therapeutic Effect of Apocynin on Bleomycin-Induced Lung Fibrosis in Rats. Inflammation 38:3, pages 1166-1180.
Crossref
Grant R. Drummond & Christopher G. Sobey. (2014) Endothelial NADPH oxidases: which NOX to target in vascular disease?. Trends in Endocrinology & Metabolism 25:9, pages 452-463.
Crossref
Ahmed Nadeem, Nahid Siddiqui, Naif O. Alharbi, Mohammad M. Alharbi, Faisal Imam & Mohamed M. Sayed-Ahmed. (2014) Glutathione modulation during sensitization as well as challenge phase regulates airway reactivity and inflammation in mouse model of allergic asthma. Biochimie 103, pages 61-70.
Crossref
Seung-Joo Nam, In Soo Oh, Young Ha Yoon, Bo In Kwon, Wonseok Kang, Hee Ja Kim, Seung Hoon Nahm, Youn-Hee Choi, Seung-Hyo Lee, Vito Racanelli & Eui-Cheol Shin. (2013) Apocynin regulates cytokine production of CD8+ T cells. Clinical and Experimental Medicine 14:3, pages 261-268.
Crossref
Ronaldo P. PanganibanBecky M. VonakisFaoud T. IshmaelCristiana Stellato. (2014) Coordinated Post-Transcriptional Regulation of the Chemokine System: Messages from CCL2. Journal of Interferon & Cytokine Research 34:4, pages 255-266.
Crossref
Kaiyu Wang, Linlin Li, Yan Song, Xiaocui Ye, Shaolian Fu, Jie Jiang & Sha Li. (2013) Improvement of Pharmacokinetics Behavior of Apocynin by Nitrone Derivatization: Comparative Pharmacokinetics of Nitrone-Apocynin and its Parent Apocynin in Rats. PLoS ONE 8:7, pages e70189.
Crossref
Saurabh Aggarwal, Christine M. Gross, Shruti Sharma, Jeffrey R. Fineman & Stephen M. Black. 2011. Comprehensive Physiology. Comprehensive Physiology 1011 1034 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.