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Research Article

Ameliorative potential of alpha-ketoglutaric acid (AKG) on acute lung injuries induced by ammonia inhalation in rats

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Pages 435-444 | Received 14 Feb 2012, Accepted 14 Aug 2012, Published online: 14 Sep 2012

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Shang-Ling Xiong, Gyu Tae Lim, Shang-Jun Yin, Jinhyuk Lee, Jae-Rin Lee, Myong-Joon Hahn, Jun-Mo Yang, Yong-Doo Park & Guo-Ying Qian. (2020) Inhibitory effect of α-ketoglutaric acid on α-glucosidase: integrating molecular dynamics simulation and inhibition kinetics. Journal of Biomolecular Structure and Dynamics 38:12, pages 3496-3503.
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Mahtab Tapak, Somaye Sadeghi, Tooba Ghazanfari & Nariman Mosaffa. (2023) Chemical exposure and alveolar macrophages responses: ‘the role of pulmonary defense mechanism in inhalation injuries’. BMJ Open Respiratory Research 10:1, pages e001589.
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Qiaohua Luo, Rendong Qian, Zongsheng Qiu, Fernando Y. Yamamoto, Yingying Du, Xiaowen Lin, Jianhua Zhao & Qiyou Xu. (2023) Dietary α-ketoglutarate alleviates glycinin and β-conglycinin induced damage in the intestine of mirror carp (Cyprinus carpio). Frontiers in Immunology 14.
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Vaishali Gupta, Chris Major Ncho, Akshat Goel, Chae-Mi Jeong & Yang-Ho Choi. (2022) Effects of In Ovo Injection of α-Ketoglutaric Acid on Hatchability, Growth, Plasma Metabolites, and Antioxidant Status of Broilers. Antioxidants 11:11, pages 2102.
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Balakyntiewshisha Lyngdoh Kynshi, Meguovilie Sachu & Mayashree B. Syiem. (2022) Unrestricted availability of α-ketoglutarate influences biomass production in the cyanobacterium Nostoc muscorum Meg 1 by impacting rates of photosynthesis, nitrogen fixation and lipid synthesis. Journal of Applied Phycology 34:3, pages 1363-1375.
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Chiranjiv Pradhan, Uzma Soharwardi, Namitha Dileep, Nikhila Peter, Rachel Fernandez, Sweta Das, Amitha Kurian & Preetham Elumalai. (2021) Suitable ratio of dietary L-carnitine and α-ketoglutarate improves growth and health performance in Nile tilapia, Oreochromis niloticus. Fish Physiology and Biochemistry 47:6, pages 1933-1950.
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Xin-Yu Li, Hai-Jia Hou, Bing Dai, Wei Tan & Hong-Wen Zhao. (2021) Adult with mass burnt lime aspiration: A case report and literature review. World Journal of Clinical Cases 9:32, pages 9935-9941.
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Qingzi Lei, Weizhu Zeng, Jingwen Zhou & Guocheng Du. (2019) Efficient separation of α-ketoglutarate from Yarrowia lipolytica WSH-Z06 culture broth by converting pyruvate to l-tyrosine. Bioresource Technology 292, pages 121897.
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Muhammad Haroon, Haojie Yu, Li Wang, Raja Summe Ullah, Fazal Haq & Lisong Teng. (2019) Synthesis and characterization of carboxymethyl starch-g-polyacrylic acids and their properties as adsorbents for ammonia and phenol. International Journal of Biological Macromolecules 138, pages 349-358.
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Renyi Li, Xianqi Dai, Zhen Feng, Yi Li, Mingyu Zhao, Jing Liu, Huiting Li, Yang Chen, Yaqiang Ma & Yanan Tang. (2019) Effect of toxic ligands on O 2 binding to heme and their toxicity mechanism . Physical Chemistry Chemical Physics 21:27, pages 14957-14963.
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Fazal Haq, Haojie Yu, Li Wang, Lisong Teng, Muhammad Haroon, Rizwan Ullah Khan, Sahid Mehmood, Bilal-Ul-Amin, Raja Summe Ullah, Amin Khan & Ahsan Nazir. (2019) Advances in chemical modifications of starches and their applications. Carbohydrate Research 476, pages 12-35.
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Justin N. Vigil, Philip L. Sabatini, Laura C. Hill, David P. Swain & J. David Branch. (2018) Ammonia Inhalation Does Not Increase Deadlift 1-Repetition Maximum in College-Aged Male and Female Weight Lifters. Journal of Strength and Conditioning Research 32:12, pages 3383-3388.
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Shaojuan Liu, Liuqin He & Kang Yao. (2018) The Antioxidative Function of Alpha-Ketoglutarate and Its Applications. BioMed Research International 2018, pages 1-6.
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Lin Gou, Jinhyuk Lee, Jun-Mo Yang, Yong-Doo Park, Hai-Meng Zhou, Yi Zhan & Zhi-Rong Lü. (2017) The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. International Journal of Biological Macromolecules 105, pages 1654-1662.
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R AliA ShahidN AliSK HasanF MajedS Sultana. (2016) Amelioration of Benzo[a]pyrene-induced oxidative stress and pulmonary toxicity by Naringenin in Wistar rats: A plausible role of COX-2 and NF-κB. Human & Experimental Toxicology 36:4, pages 349-364.
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Srinivasan Dasarathy, Rajeshwar P. Mookerjee, Veronika Rackayova, Vinita Rangroo Thrane, Balasubramaniyan Vairappan, Peter Ott & Christopher F. Rose. (2016) Ammonia toxicity: from head to toe?. Metabolic Brain Disease 32:2, pages 529-538.
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Weizhu Zeng, Fang Fang, Song Liu, Guocheng Du, Jian Chen & Jingwen Zhou. (2016) Comparative genomics analysis of a series of Yarrowia lipolytica WSH-Z06 mutants with varied capacity for α-ketoglutarate production. Journal of Biotechnology 239, pages 76-82.
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Guocheng Du, Long Liu & Jian Chen. 2015. Industrial Biorefineries & White Biotechnology. Industrial Biorefineries & White Biotechnology 409 444 .
Igor G. Morgunov, Svetlana V. Kamzolova & Vladimir A. Samoilenko. (2013) Enhanced α-ketoglutaric acid production and recovery in Yarrowia lipolytica yeast by effective pH controlling. Applied Microbiology and Biotechnology 97:19, pages 8711-8718.
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