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Experimental Lung Research Volume 2, 1981 - Issue 3
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Original Article

Epithelial-Mesenchymal Associations of Cells in Human Pulmonary Fibrosis and in BHT-Oxygen-Induced Fibrosis in Mice

Arnold R. Brody Laboratory of Pulmonary Function and Toxicology, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, North Carolina, 27709; The INSERM Group U82. Hospital Bichat, 170 Boulevard Ney, 75877, Paris, Cedex, 18, France; The Biology Division Oak Ridge National Laboratory, Oak Ridge, Tennessee, 3 7830
,
Paul Soler Laboratory of Pulmonary Function and Toxicology, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, North Carolina, 27709; The INSERM Group U82. Hospital Bichat, 170 Boulevard Ney, 75877, Paris, Cedex, 18, France; The Biology Division Oak Ridge National Laboratory, Oak Ridge, Tennessee, 3 7830
,
Francoise Basset Laboratory of Pulmonary Function and Toxicology, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, North Carolina, 27709; The INSERM Group U82. Hospital Bichat, 170 Boulevard Ney, 75877, Paris, Cedex, 18, France; The Biology Division Oak Ridge National Laboratory, Oak Ridge, Tennessee, 3 7830
,
Wanda M. Haschek Laboratory of Pulmonary Function and Toxicology, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, North Carolina, 27709; The INSERM Group U82. Hospital Bichat, 170 Boulevard Ney, 75877, Paris, Cedex, 18, France; The Biology Division Oak Ridge National Laboratory, Oak Ridge, Tennessee, 3 7830
&
Hanspeter Witschi Laboratory of Pulmonary Function and Toxicology, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, North Carolina, 27709; The INSERM Group U82. Hospital Bichat, 170 Boulevard Ney, 75877, Paris, Cedex, 18, France; The Biology Division Oak Ridge National Laboratory, Oak Ridge, Tennessee, 3 7830
Pages 207-220 | Received 26 Nov 1980, Accepted 02 Mar 1981, Published online: 02 Jul 2009

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Rakesh K. Kumar & Athol W.J. Lykke. (1995) Messages and handshakes: Cellular interactions in pulmonary fibrosis. Pathology 27:1, pages 18-26.
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Gary M. Velan, Rakesh K. Kumar & David D. Cohen. (1993) Pulmonary Inflammation and Fibrosis Following Subacute Inhalational Exposure to Silica: Determinants of Progression. Pathology 25:3, pages 282-290.
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I. Y. R. Adamson, L. Young & G. M. King. (1991) Reciprocal Epithelial: Fibroblast Interactions in the Control of Fetal and Adult Rat Lung Cells in Culture. Experimental Lung Research 17:4, pages 821-835.
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Ian Y. R. Adamson & Gillian M. King. (1985) Epithelial-Mesenchymal Interactions in Postnatal Rat Lung Growth. Experimental Lung Research 8:4, pages 261-274.
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Christina C. Leslie, Kathleen McCormick-Shannon, Peter C. Robinson & Robert J. Mason. (1985) Stimulation of DNA Synthesis in Cultured Rat Alveolar Type II Cells. Experimental Lung Research 8:1, pages 53-66.
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Ru Wang & Yan-Mei Yang. (2023) Identification of potential biomarkers for idiopathic pulmonary fibrosis and validation of TDO2 as a potential therapeutic target . World Journal of Cardiology 15:6, pages 293-308.
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Tatsuya Tsukui, Satoshi Ueha, Shigeyuki Shichino, Yutaka Inagaki & Kouji Matsushima. (2015) Intratracheal Cell Transfer Demonstrates the Profibrotic Potential of Resident Fibroblasts in Pulmonary Fibrosis. The American Journal of Pathology 185:11, pages 2939-2948.
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Ivor S. Douglas, Fernando Diaz del Valle, Robert A. Winn & Norbert F. Voelkel. (2006) β-Catenin in the Fibroproliferative Response to Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology 34:3, pages 274-285.
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Faye E. Sirianni, Fanny S. F. Chu & David C. Walker. (2003) Human Alveolar Wall Fibroblasts Directly Link Epithelial Type 2 Cells to Capillary Endothelium. American Journal of Respiratory and Critical Care Medicine 168:12, pages 1532-1537.
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Vibha Lama, Bethany B. Moore, Paul Christensen, Galen B. Toews & Marc Peters-Golden. (2002) Prostaglandin E 2 Synthesis and Suppression of Fibroblast Proliferation by Alveolar Epithelial Cells Is Cyclooxygenase-2–Dependent . American Journal of Respiratory Cell and Molecular Biology 27:6, pages 752-758.
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Frank Werner, Mukesh K. Jain, Mark W. Feinberg, Nicholas E.S. Sibinga, Andrea Pellacani, Philippe Wiesel, Michael T. Chin, James N. Topper, Mark A. Perrella & Mu-En Lee. (2000) Transforming Growth Factor-β1 Inhibition of Macrophage Activation Is Mediated via Smad3. Journal of Biological Chemistry 275:47, pages 36653-36658.
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Russell Ross. (1999) Atherosclerosis — An Inflammatory Disease. New England Journal of Medicine 340:2, pages 115-126.
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Bruce D. UhalIravati JoshiW. Frank HughesCarlos Ramos, Annie Pardo & Moises Selman. (1998) Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. American Journal of Physiology-Lung Cellular and Molecular Physiology 275:6, pages L1192-L1199.
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Cairns. (2001) Mast cell tryptase and its role in tissue remodelling. Clinical & Experimental Allergy 28:12, pages 1460-1463.
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PETER A. WARD & GARY W. HUNNINGHAKE. (1998) Lung Inflammation and Fibrosis. American Journal of Respiratory and Critical Care Medicine 157:4, pages S123-S129.
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Annie Pardo, Karen Ridge, Bruce Uhal, J. Iasha Sznajder & Mois?s Selman. (1997) Lung alveolar epithelial cells synthesize interstitial collagenase and gelatinases A and B in vitro. The International Journal of Biochemistry & Cell Biology 29:6, pages 901-910.
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Bryan Corrin. 1996. ARDS Acute Respiratory Distress in Adults. ARDS Acute Respiratory Distress in Adults 37 46 .
M. Kasper, D. Schuh & M. Müller. (1994) Bauhinia purpurea lectin (BPA) binding of rat type I pneumocytes: Alveolar epithelial alterations after radiation-induced lung injury. Experimental and Toxicologic Pathology 46:4-5, pages 361-367.
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M. Kasper, Th. Rudolf, M. Haase, D. Schuh & M. Müller. (1993) Changes in cytokeratin, vimentin and desmoplakin distribution during the repair of irradiation-induced lung injury in adult rats. Virchows Archiv B Cell Pathology Including Molecular Pathology 64:1, pages 271-279.
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J. R. G. NASH, P. J. MCLAUGHLIN, D. BUTCHER & B. CORRIN. (2007) Expression of tumour necrosis factor‐α in cryptogenic fibrosing alveolitis. Histopathology 22:4, pages 343-347.
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HANSPETER WITSCHI, ALVIN M. MALKINSON & JOHN A. THOMPSON. 1993. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells 185 212 .
A Francine Tryka & Hanspeter Witschi. (1991) Modulation of Cellular Repair Response Patterns. Chest 99:3, pages 28S-30S.
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Teruyo Sakakura. 1991. 165 202 .
James B. Mangum, Jeffrey I. Everitt, James C. Bonner, Lynne R. Moore & Arnold R. Brody. (1990) Co-culture of primary pulmonary cells to model alveolar injury and translocation of proteins. In Vitro Cellular & Developmental Biology 26:12, pages 1135-1143.
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H Witschi. (1990) Responses of the lung to toxic injury.. Environmental Health Perspectives 85, pages 5-13.
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Gregory C. Rhodes, Athol W. J. Lykke, John W. Tapsall & Lance W. Smith. (2005) Abnormal alveolar epithelial repair associated with failure of resolution in experimental streptococcal pneumonia. The Journal of Pathology 159:3, pages 245-253.
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Gregory C. Rhodes, John W. Tapsall & Athol W. J. Lykke. (1989) Alveolar epithelial responses in experimental streptococcal pneumonia. The Journal of Pathology 157:4, pages 347-357.
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Hanspeter Witschi, Alvin M. Malkinson & John A. Thompson. (1989) Metabolism and pulmonary toxicity of butylated hydroxytoluene (BHT). Pharmacology & Therapeutics 42:1, pages 89-113.
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David P. Penney. 1988. 231 269 .
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M.E. Pecquet Goad, A. Francine Tryka & H.P. Witschi. (1987) Acute respiratory failure induced by bleomycin and hyperoxia: Pulmonary edema, cell kinetics, and morphology. Toxicology and Applied Pharmacology 90:1, pages 10-22.
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A.W.J. Lykke, G.C. Rhodes, R.K. Kumar & G.J. Smith. (1987) Pulmonary responses to atmospheric pollutants. Experimental pathology 31:4, pages 243-248.
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