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Experimental Lung Research Volume 16, 1990 - Issue 6
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Original Article

The Effects of Different Silicas on Arachidonic Acid Metabolism in Alveolar Macrophages

Mark D. Englen From the Laboratory of Molecular and Cellular Inflammation, Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington; Ligand Pharmaceuticals, 9393 Towne Center Drive, San Diego, California; and Plum Island Animal Disease Center, NAA/ARS/USDA, Greenport, New York
,
Stephen M. Taylor From the Laboratory of Molecular and Cellular Inflammation, Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington; Ligand Pharmaceuticals, 9393 Towne Center Drive, San Diego, California; and Plum Island Animal Disease Center, NAA/ARS/USDA, Greenport, New York
,
William W. Laegreid From the Laboratory of Molecular and Cellular Inflammation, Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington; Ligand Pharmaceuticals, 9393 Towne Center Drive, San Diego, California; and Plum Island Animal Disease Center, NAA/ARS/USDA, Greenport, New York
,
Ronald M. Silflow From the Laboratory of Molecular and Cellular Inflammation, Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington; Ligand Pharmaceuticals, 9393 Towne Center Drive, San Diego, California; and Plum Island Animal Disease Center, NAA/ARS/USDA, Greenport, New York
&
R. Wes Leid From the Laboratory of Molecular and Cellular Inflammation, Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington; Ligand Pharmaceuticals, 9393 Towne Center Drive, San Diego, California; and Plum Island Animal Disease Center, NAA/ARS/USDA, Greenport, New York
Pages 691-709 | Received 19 Nov 1989, Published online: 02 Jul 2009

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DouglasC. Kuhn & LaurenceM. Demers. (1996) Interactions of the Alveolar Macrophage and the Fibroblast: Regulation of Basal and Silica-Activated Eicosanoid Production. Applied Occupational and Environmental Hygiene 11:7, pages 919-922.
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RichardD. Dey, Charles Stanley, JohnA. Blackford$suffix/text()$suffix/text(), Jerry Harness, John Durham, Vincent Castranova & Ann Hubbs. (1996) Inhaled Silica Dust Increases Nitric Oxide and Cytokine Production Associated with Collagen Synthesis and Fibrosis in Rats. Applied Occupational and Environmental Hygiene 11:7, pages 914-918.
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LaurenceM. Demers, LesleyJ. Gaydos, JohnL. Stauffer & DouglasC. Kuhn. (1996) Bacterial Endotoxin Primes the Human Alveolar Macrophage for Subsequent Stimulation by Silica but Silica Does Not Prime for Stimulation by Bacterial Endotoxin. Applied Occupational and Environmental Hygiene 11:7, pages 909-913.
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Dana Savici, Bei He, Lois J. Geist, Martha M. Monick & Gary W. Hunninghake. (1994) Silica Increases Tumor Necrosis Factor (TNF) Production, in Part, by Upregulating the TNF Promoter. Experimental Lung Research 20:6, pages 613-625.
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Julie Muller, Ilse Decordier, Peter H. Hoet, Noömi Lombaert, Leen Thomassen, François Huaux, Dominique Lison & Micheline Kirsch-Volders. (2008) Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells. Carcinogenesis 29:2, pages 427-433.
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Mary Cunningham. 2007. Nanotoxicology. Nanotoxicology 173 196 .
Scott P. Levick, David C. Loch, Stephen M. Taylor & Joseph S. Janicki. (2007) Arachidonic Acid Metabolism as a Potential Mediator of Cardiac Fibrosis Associated with Inflammation. The Journal of Immunology 178:2, pages 641-646.
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Julie Muller, François Huaux & Dominique Lison. (2006) Respiratory toxicity of carbon nanotubes: How worried should we be?. Carbon 44:6, pages 1048-1056.
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François Huaux. 2005. Inhalation Toxicology, Second Edition. Inhalation Toxicology, Second Edition 307 333 .
I Beck-Speier, N Dayal, E Karg, K L Maier, C Roth, A Ziesenis & J Heyder. (2001) Agglomerates of ultrafine particles of elemental carbon and TiO2 induce generation of lipid mediators in alveolar macrophages.. Environmental Health Perspectives 109:suppl 4, pages 613-618.
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Jianbo Hu, Gheorghe T Braileanu & Mark A Mirando. (2001) Oxytocin stimulates prostaglandin F2α secretion from porcine endometrial cells through activation of calcium-dependent protein kinase C☆. Prostaglandins & Other Lipid Mediators 65:2-3, pages 85-101.
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BROOKE T. MOSSMAN & ANDREW CHURG. (1998) Mechanisms in the Pathogenesis of Asbestosis and Silicosis. American Journal of Respiratory and Critical Care Medicine 157:5, pages 1666-1680.
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LING LIU, JUDITH A. LEECH, R. BRUCE URCH & FRANCES S. SILVERMAN. (1997) In Vivo Salicylate Hydroxylation: A Potential Biomarker for Assessing Acute Ozone Exposure and Effects in Humans . American Journal of Respiratory and Critical Care Medicine 156:5, pages 1405-1412.
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K.A. Tysseling, M. Uzumcu, T.A. Hoagland, R.C. Crain & M.A. Mirandot. (1996) The role of phosphoinositide-derived second messengers in oxytocin-stimulated prostaglandin F2α release from endometrium of pigs. Domestic Animal Endocrinology 13:5, pages 411-420.
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Pierre F. Piguet. 1994. Xenobiotics and Inflammation. Xenobiotics and Inflammation 283 300 .
D.C. Kuhn, J.W. Griffith, J.L. Stauffer, S. Riling & L.M. Demers. (1993) Characterization of alveolar macrophage eicosanoid production in a non-human primate model of mineral dust exposure. Prostaglandins 46:3, pages 207-220.
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Yongyut Rojanasakul, LiYing Wang, Andre H. Hoffman, Xianglin Shi, Nar S. Dalal, Daniel E. Banks & Joseph K. H. Ma. (1993) Mechanisms of Hydroxyl Free Radical-induced Cellular Injury and Calcium Overloading in Alveolar Macrophages. American Journal of Respiratory Cell and Molecular Biology 8:4, pages 377-383.
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Mark D. Englen, Stephen M. Taylor, William W. Laegreid, Ronald M. Silflow & R. Wes Leid. (1992) Diminished Arachidonic Acid Metabolite Release by Bovine Alveolar Macrophages Exposed to Surface-modified Silica. American Journal of Respiratory Cell and Molecular Biology 6:5, pages 527-534.
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