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Ultrastructural Pathology Volume 38, 2014 - Issue 5
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Research Article

The Protective Effect of Curcumin on Hepatotoxicity and Ultrastructural Damage Induced by Cisplatin

Ying WangZhongnan Hospital of Wuhan University, The Second College of Clinical Medicine of Wuhan University Wuhan, HubeiPeople’s Republic of China;Department of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease School of Medicine, Wuhan University, Wuhan, HubeiPeople’s Republic of China
, BS,
Peng-Chao HuDepartment of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease School of Medicine, Wuhan University, Wuhan, HubeiPeople’s Republic of China
, MS,
Fang-Fang GaoDepartment of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease School of Medicine, Wuhan University, Wuhan, HubeiPeople’s Republic of China
, BS,
Jia-Wei LvDepartment of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease School of Medicine, Wuhan University, Wuhan, HubeiPeople’s Republic of China
, MB,
Shuai XuDepartment of Pathology, Hanyang Hospital of Wuhan University of Science and Technology Subsidiary Wuhan, HubeiPeople’s Republic of China
, BS,
Chang-Chun KuangDepartment of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease School of Medicine, Wuhan University, Wuhan, HubeiPeople’s Republic of China
, MS,
Lei WeiDepartment of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease School of Medicine, Wuhan University, Wuhan, HubeiPeople’s Republic of China
, MD, PhD &
Jing-Wei ZhangZhongnan Hospital of Wuhan University, The Second College of Clinical Medicine of Wuhan University Wuhan, HubeiPeople’s Republic of ChinaCorrespondence[email protected]
, MD show all
Pages 358-362 | Received 29 Apr 2014, Accepted 06 Jun 2014, Published online: 31 Jul 2014

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Asieh Hosseini, Danyal Rasaie, Sara Soleymani Asl, Amir Nili Ahmadabadi & Akram Ranjbar. (2021) Evaluation of the protective effects of curcumin and nanocurcumin against lung injury induced by sub-acute exposure to paraquat in rats. Toxin Reviews 40:4, pages 1233-1241.
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Ying Wang, Xuejuan Wang, Yanwu Wang, Rong Fan, Chao Qiu, Shan Zhong, Lei Wei & Daji Luo. (2015) Effect of Cadmium on Cellular Ultrastructure in Mouse Ovary. Ultrastructural Pathology 39:5, pages 324-328.
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Ngoc The Nguyen, Quynh Anh Bui, Hoang Huong Nhu Nguyen, Tien Thanh Nguyen, Khanh Linh Ly, Ha Le Bao Tran, Vu Nguyen Doan, Tran Thi Yen Nhi, Ngoc Hoa Nguyen, Ngoc Hao Nguyen, Ngoc Quyen Tran & Dinh Trung Nguyen. (2022) Curcuminoid Co-Loading Platinum Heparin-Poloxamer P403 Nanogel Increasing Effectiveness in Antitumor Activity. Gels 8:1, pages 59.
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Asal Jalal Abadi, Sepideh Mirzaei, Mahmood Khaksary Mahabady, Farid Hashemi, Amirhossein Zabolian, Fardin Hashemi, Pourya Raee, Shahin Aghamiri, Milad Ashrafizadeh, Amir Reza Aref, Michael R. Hamblin, Kiavash Hushmandi, Ali Zarrabi & Gautam Sethi. (2021) Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects. Phytotherapy Research 36:1, pages 189-213.
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Nejat Kheiripour, Alireza Plarak, Ali Heshmati, Sara Soleimani Asl, Fereshteh Mehri, Alireza Ebadollahi‐Natanzi, Akram Ranjbar & Asieh Hosseini. (2021) Evaluation of the hepatoprotective effects of curcumin and nanocurcumin against paraquat‐induced liver injury in rats: Modulation of oxidative stress and Nrf2 pathway. Journal of Biochemical and Molecular Toxicology 35:5.
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Xianlei Jiang, Xupeng Xing, Yingbing Zhang, Chengtu Zhang, Ying Wu, Yongzhong Chen, Ru Meng, Huiqun Jia, Yuyao Cheng, Yong Zhang & Jianmin Su. (2021) Lead exposure activates the Nrf2/Keap1 pathway, aggravates oxidative stress, and induces reproductive damage in female mice. Ecotoxicology and Environmental Safety 207, pages 111231.
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Sadaf Akbari, Elnaz Kariznavi, Mahdi Jannati, Sepideh Elyasi & Zahra Tayarani-Najaran. (2020) Curcumin as a preventive or therapeutic measure for chemotherapy and radiotherapy induced adverse reaction: A comprehensive review. Food and Chemical Toxicology 145, pages 111699.
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Alessandra Scagliarini, Aline Mathey, Virginie Aires & Dominique Delmas. (2020) Xanthohumol, a Prenylated Flavonoid from Hops, Induces DNA Damages in Colorectal Cancer Cells and Sensitizes SW480 Cells to the SN38 Chemotherapeutic Agent. Cells 9:4, pages 932.
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Fairouz Sioud, Souheila Amor, Imène ben Toumia, Aida Lahmar, Virginie Aires, Leila Chekir-Ghedira & Dominique Delmas. (2020) A New Highlight of Ephedra alata Decne Properties as Potential Adjuvant in Combination with Cisplatin to Induce Cell Death of 4T1 Breast Cancer Cells In Vitro and In Vivo. Cells 9:2, pages 362.
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Harshul Batra, Shrikant Pawar & Dherya Bahl. (2019) Curcumin in combination with anti-cancer drugs: A nanomedicine review. Pharmacological Research 139, pages 91-105.
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Zhijun Liu, Pengyun Huang, Siukan Law, Haiyan Tian, Wingnang Leung & Chuanshan Xu. (2018) Preventive Effect of Curcumin Against Chemotherapy-Induced Side-Effects. Frontiers in Pharmacology 9.
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Changming Li, Xiangcheng Ge & Liguo Wang. (2017) Construction and comparison of different nanocarriers for co-delivery of cisplatin and curcumin: A synergistic combination nanotherapy for cervical cancer. Biomedicine & Pharmacotherapy 86, pages 628-636.
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Fang Zhang, Fei Yang, Hongmei Zhao & Yunxia An. (2015) Curcumin alleviates lung injury in diabetic rats by inhibiting nuclear factor- κ B pathway . Clinical and Experimental Pharmacology and Physiology 42:9, pages 956-963.
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