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Ultrastructural Pathology Volume 39, 2015 - Issue 2
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Review Article

On the Maturation of Megakaryocytes: A Review with Original Observations on Human In Vivo Cells Emphasizing Morphology and Ultrastructure

Yong-Xin RuState Key Laboratory of Experimental Hematology, Peking Union Medical College, Institute of Hematology & Blood Diseases Hospital, Beijing, China and Correspondence[email protected]
, MD,
Shi-Xuan ZhaoState Key Laboratory of Experimental Hematology, Peking Union Medical College, Institute of Hematology & Blood Diseases Hospital, Beijing, China and
, BSc,
Shu-Xu DongState Key Laboratory of Experimental Hematology, Peking Union Medical College, Institute of Hematology & Blood Diseases Hospital, Beijing, China and
, BSc,
Yi-Qing YangState Key Laboratory of Experimental Hematology, Peking Union Medical College, Institute of Hematology & Blood Diseases Hospital, Beijing, China and
, MD &
Brian EydenDepartment of Histopathology, Christie Hospital NHS Trust, Manchester, UK
, PhD
Pages 79-87 | Received 12 Sep 2014, Accepted 17 Oct 2014, Published online: 08 Jan 2015

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Yong-Xin Ru, Shi-Xuan Zhao, Shu-Xu Dong, Hao-yue Liang & Ying Wang. (2018) Systematic alteration of apoptosis: a review with ultrastructural observations on leukemia cells in vivo. Ultrastructural Pathology 42:1, pages 1-9.
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Yong-Xin Ru, Shu-Xu Dong, Hao-yue Liang & Shi-Xuan Zhao. (2016) Platelet production of megakaryocyte: A review with original observations on human in vivo cells and bone marrow. Ultrastructural Pathology 40:4, pages 163-170.
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Articles from other publishers (9)

Sergei I. Obydennyi, Sofya A. Kuznetsova, Olga S. Fedyanina, Anna Khoreva, Kirill Voronin, Alexey V. Mazurov, Anna A. Glukhova, Elena O. Artemenko, Fazoil I. Ataullakhanov, Alexey A. Maschan, Galina A. Novichkova, Anna Shcherbina & Mikhail A. Panteleev. (2023) Accelerated death of megakaryocytes from Wiskott–Aldrich syndrome patients . British Journal of Haematology 202:3, pages 645-656.
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Kathrin Olschok, Lijuan Han, Marcelo A.S. de Toledo, Janik Böhnke, Martin Graßhoff, Ivan G. Costa, Alexandre Theocharides, Angela Maurer, Herdit M. Schüler, Eva Miriam Buhl, Kristina Pannen, Julian Baumeister, Milena Kalmer, Siddharth Gupta, Peter Boor, Deniz Gezer, Tim H. Brümmendorf, Martin Zenke, Nicolas Chatain & Steffen Koschmieder. (2021) CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes. Stem Cell Reports 16:11, pages 2768-2783.
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Fizzah A. Choudry, Frederik O. Bagger, Iain C. Macaulay, Samantha Farrow, Frances Burden, Carly Kempster, Harriet McKinney, Lars R. Olsen, Ni Huang, Kate Downes, Thierry Voet, Rakesh Uppal, John F. Martin, Anthony Mathur, Willem H. Ouwehand, Elisa Laurenti, Sarah A. Teichmann & Mattia Frontini. (2021) Transcriptional characterization of human megakaryocyte polyploidization and lineage commitment. Journal of Thrombosis and Haemostasis 19:5, pages 1236-1249.
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Yong-Xin Ru, Shu-Xu Dong, Chun-Hui Xu, Shi-Xuan Zhao, Hua-Mei Zhang, Hao-Yue Liang, Min Fen, Feng-Kui Zhang, Ying-Dai Gao, Shu-Lin Qi & Hong-Cai Shang. (2021) Bone marrow mesenchymal cells: polymorphism associated with transformation of rough endoplasmic reticulum. Blood Science 3:1, pages 6-13.
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Cleopatra Kozlowski, Aaron Fullerton, Gary Cain, Paula Katavolos, Joseph Bravo & Jacqueline M. Tarrant. (2018) Proof of Concept for an Automated Image Analysis Method to Quantify Rat Bone Marrow Hematopoietic Lineages on H&E Sections. Toxicologic Pathology 46:3, pages 336-347.
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Christian Di Buduo, Alessandra Balduini & Francesco Moccia. (2016) Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis. International Journal of Molecular Sciences 17:12, pages 2055.
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Alicia Aguilar, Fabien Pertuy, Anita Eckly, Catherine Strassel, Dominique Collin, Christian Gachet, François Lanza & Catherine Léon. (2016) Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation. Blood 128:16, pages 2022-2032.
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Nikola Ivetic, Ishac Nazi, Nadia Karim, Rumi Clare, James W. Smith, Jane C. Moore, Kristin J. Hope, John G. Kelton & Donald M. Arnold. (2016) Producing megakaryocytes from a human peripheral blood source. Transfusion 56:5, pages 1066-1074.
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J.N. Thon, D.A. Medvetz, S.M. Karlsson & J.E. ItalianoJrJr. (2015) Road blocks in making platelets for transfusion. Journal of Thrombosis and Haemostasis 13, pages S55-S62.
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