102
Views
97
CrossRef citations to date
0
Altmetric
Original Article

Microvasculature in Brain Biopsy Specimens from Patients with Alzheimer's Disease: An Immunohistochemical and Ultrastructural Study

, , , , , , & show all
Pages 333-348 | Accepted 06 Aug 1993, Published online: 10 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

JOHANNES A. RHODIN & TOM THOMAS. (2001) A Vascular Connection to Alzheimer's Disease. Microcirculation 8:4, pages 207-220.
Read now
Eun Young Lee, Sook Young Lee, Tae Soo Lee, Je Geun Chi, Woong Choi, Yoo-Hun Suh. (2000) Ultrastructural Changes in Microvessel With Age in the Hippocampus of Senescence-Accelerated Mouse (SAM)-P/10. Experimental Aging Research 26:1, pages 3-14.
Read now
Brian Eyden. (1999) Readers' Forum. Ultrastructural Pathology 23:5, pages 355-357.
Read now
George S. Zubenko. (1997) Molecular Neurobiology of Alzheimer's Disease (Syndrome?). Harvard Review of Psychiatry 5:4, pages 177-213.
Read now
John M. Wells, Anil Amaratunga, Daniel C. McKenna, Carmela R. Abraham & Richard E. Fine. (1995) Amyloid β-protein precursor and apolipoprotein E production in cultured cerebral endothelial cells isolated from brains of patients with neurodegenerative disorders at autopsy. Amyloid 2:4, pages 229-233.
Read now

Articles from other publishers (92)

Elisa Canepa, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Begona Gamallo‐Lana, Roberto Guzman‐Hernandez, Nicole L. Lemon, Federica Angiulli, Ludovic Debure, Marc A. Ilies, Leif Østergaard, Thomas Wisniewski, Eugenio Gutiérrez‐Jiménez, Adam C. Mar & Silvia Fossati. (2023) FDA‐approved carbonic anhydrase inhibitors reduce amyloid β pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness. Alzheimer's & Dementia 19:11, pages 5048-5073.
Crossref
Shino D Magaki & Harry V Vinters. (2023) Evaluating when (and how) hypertension may be ‘good for your brain’. Brain Communications 5:2.
Crossref
Anna M. De Kort, H. Bea Kuiperij, Tainá M. Marques, Lieke Jäkel, Emma van den Berg, Iris Kersten, Hugo E. P. van Berckel‐Smit, Marco Duering, Erik Stoops, Wilson F. Abdo, Ingeborg Rasing, Sabine Voigt, Emma A. Koemans, Kanishk Kaushik, Andrew Davock Warren, Steven M. Greenberg, Gunnar Brinkmalm, Gisela M. Terwindt, Marieke J. H. Wermer, Floris H. B. M. Schreuder, Catharina J. M. Klijn & Marcel M. Verbeek. (2023) Decreased Cerebrospinal Fluid Amyloid β 38, 40, 42, and 43 Levels in Sporadic and Hereditary Cerebral Amyloid Angiopathy. Annals of Neurology.
Crossref
Monica Gireud-Goss, Alexis F. Mack, Louise D. McCullough & Akihiko Urayama. (2020) Cerebral Amyloid Angiopathy and Blood-Brain Barrier Dysfunction. The Neuroscientist 27:6, pages 668-684.
Crossref
Shino Magaki, Zesheng Chen, Mohammad Haeri, Christopher K. Williams, Negar Khanlou, William H. Yong & Harry V. Vinters. (2021) Charcot–Bouchard aneurysms revisited: clinicopathologic correlations. Modern Pathology 34:12, pages 2109-2121.
Crossref
Julie Ouellette & Baptiste Lacoste. (2021) From Neurodevelopmental to Neurodegenerative Disorders: The Vascular Continuum. Frontiers in Aging Neuroscience 13.
Crossref
Haoshen Shi, Yosef Koronyo, Altan Rentsendorj, Dieu-Trang Fuchs, Julia Sheyn, Keith L. Black, Nazanin Mirzaei & Maya Koronyo-Hamaoui. (2021) Retinal Vasculopathy in Alzheimer’s Disease. Frontiers in Neuroscience 15.
Crossref
Joseph O. Ojo, Jon M. Reed, Gogce Crynen, Prashanthi Vallabhaneni, James Evans, Benjamin Shackleton, Maximillian Eisenbaum, Charis Ringland, Anastasia Edsell, Michael Mullan, Fiona Crawford & Corbin Bachmeier. (2021) Molecular Pathobiology of the Cerebrovasculature in Aging and in Alzheimers Disease Cases With Cerebral Amyloid Angiopathy. Frontiers in Aging Neuroscience 13.
Crossref
Haoshen Shi, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Kolja Wawrowsky, Shouri Lahiri, Keith L. Black & Maya Koronyo-Hamaoui. (2020) Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer’s disease. Acta Neuropathologica Communications 8:1.
Crossref
Francisco Fernandez‐Klett, Lasse Brandt, Camila Fernández‐Zapata, Basim Abuelnor, Jinte Middeldorp, Jacqueline A. Sluijs, Maurice Curtis, Richard Faull, Laura W. Harris, Sabine Bahn, Elly M. Hol & Josef Priller. (2020) Denser brain capillary network with preserved pericytes in Alzheimer's disease. Brain Pathology 30:6, pages 1071-1086.
Crossref
Karan Govindpani, Laura G McNamara, Nicholas R Smith, Chitra Vinnakota, Henry J Waldvogel, Richard LM Faull & Andrea Kwakowsky. (2019) Vascular Dysfunction in Alzheimer’s Disease: A Prelude to the Pathological Process or a Consequence of It?. Journal of Clinical Medicine 8:5, pages 651.
Crossref
Shino Magaki, Zhaoyi Tang, Spencer Tung, Christopher K. Williams, Darrick Lo, William H. Yong, Negar Khanlou & Harry V. Vinters. (2018) The effects of cerebral amyloid angiopathy on integrity of the blood-brain barrier. Neurobiology of Aging 70, pages 70-77.
Crossref
H. V. Vinters, C. Zarow, E. Borys, J. D. Whitman, S. Tung, W. G. Ellis, L. Zheng & H. C. Chui. (2018) Review: Vascular dementia: clinicopathologic and genetic considerations. Neuropathology and Applied Neurobiology 44:3, pages 247-266.
Crossref
Ellis S. van EttenMarcel M. VerbeekJeroen van der GrondRonald ZielmanSanneke van RoodenErik W. van ZwetAnna M. van OpstalJoost HaanSteven M. GreenbergMark A. van BuchemMarieke J.H. WermerGisela M. Terwindt. (2017) β-Amyloid in CSF. Neurology 88:2, pages 169-176.
Crossref
Eric S. Hald, Connor D. Timm & Patrick W. Alford. (2016) Amyloid Beta Influences Vascular Smooth Muscle Contractility and Mechanoadaptation. Journal of Biomechanical Engineering 138:11.
Crossref
Yun Zhai, Toru Yamashita, Yumiko Nakano, Zhuoran Sun, Jingwei Shang, Tian Feng, Ryuta Morihara, Yusuke Fukui, Yasuyuki Ohta, Nozomi Hishikawa & Koji Abe. (2016) Chronic Cerebral Hypoperfusion Accelerates Alzheimer’s Disease Pathology with Cerebrovascular Remodeling in a Novel Mouse Model. Journal of Alzheimer's Disease 53:3, pages 893-905.
Crossref
Kakulavarapu V. Rama Rao & Tammy Kielian. (2015) Neuron–astrocyte interactions in neurodegenerative diseases: Role of neuroinflammation. Clinical and Experimental Neuroimmunology 6:3, pages 245-263.
Crossref
S. Briyal, C. Nguyen, M. Leonard & A. Gulati. (2015) Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer’s disease. Neuroscience 301, pages 1-11.
Crossref
Dharmini C. Mehta, Jennifer L. Short, Sarah N. Hilmer & Joseph A. Nicolazzo. (2014) Drug Access to the Central Nervous System in Alzheimer’s Disease: Preclinical and Clinical Insights. Pharmaceutical Research 32:3, pages 819-839.
Crossref
Harry V. Vinters. (2015) Emerging Concepts in Alzheimer's Disease. Annual Review of Pathology: Mechanisms of Disease 10:1, pages 291-319.
Crossref
Ethan A. Winkler, Abhay P. Sagare & Berislav V. Zlokovic. (2014) The Pericyte: A Forgotten Cell Type with Important Implications for Alzheimer's Disease?. Brain Pathology 24:4, pages 371-386.
Crossref
Cory Toth. 2014. Diabetes and the Nervous System. Diabetes and the Nervous System 489 511 .
Piotr Religa, Renhai Cao, Dorota Religa, Yuan Xue, Nenad Bogdanovic, David Westaway, Hugo H. Marti, Bengt Winblad & Yihai Cao. (2013) VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival. Scientific Reports 3:1.
Crossref
Cheryl A. Hawkes, Maureen Gatherer, Matthew M. Sharp, Adrienne Dorr, Ho Ming Yuen, Rajesh Kalaria, Roy O. Weller & Roxana O. Carare. (2013) Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid‐β from the mouse brain. Aging Cell 12:2, pages 224-236.
Crossref
Paul M. Thompson & Harry V. Vinters. 2012. Molecular Biology of Neurodegenerative Diseases. Molecular Biology of Neurodegenerative Diseases 1 40 .
Harry V. Vinters, Spencer Tung & Orestes E. Solis. 2012. Non-fibrillar Amyloidogenic Protein Assemblies - Common Cytotoxins Underlying Degenerative Diseases. Non-fibrillar Amyloidogenic Protein Assemblies - Common Cytotoxins Underlying Degenerative Diseases 37 60 .
Anand Viswanathan & Steven M. Greenberg. (2011) Cerebral amyloid angiopathy in the elderly. Annals of Neurology 70:6, pages 871-880.
Crossref
Ethan A Winkler, Robert D Bell & Berislav V Zlokovic. (2011) Central nervous system pericytes in health and disease. Nature Neuroscience 14:11, pages 1398-1405.
Crossref
Nektaria Nicolakakis & Edith Hamel. (2011) Neurovascular function in Alzheimer's disease patients and experimental models. Journal of Cerebral Blood Flow & Metabolism 31:6, pages 1354-1370.
Crossref
James Scott Miners, Patrick Kehoe & Seth Love. (2011) Neprilysin Protects against Cerebral Amyloid Angiopathy and Aβ-Induced Degeneration of Cerebrovascular Smooth Muscle Cells. Brain Pathology, pages no-no.
Crossref
Robin AltmanJohn C. Rutledge. (2010) The vascular contribution to Alzheimer's disease. Clinical Science 119:10, pages 407-421.
Crossref
Joseph A Nicolazzo & Dharmini C Mehta. (2010) Transport of drugs across the blood–brain barrier in Alzheimer’s disease. Therapeutic Delivery 1:4, pages 595-611.
Crossref
Ryan Clare, Victoria G. King, Martin Wirenfeldt & Harry V. Vinters. (2010) Synapse loss in dementias. Journal of Neuroscience Research 88:10, pages 2083-2090.
Crossref
Susan K. Lemieux, Carrie A. Smith-Bell, Jered R Wells, Nnadozie M. Ezerioha, Jeffrey S. Carpenter, D. Larry Sparks & Bernard G. Schreurs. (2010) Neurovascular changes measured by time-of-flight MR angiography in cholesterol-fed rabbits with cortical amyloid β-peptide accumulation. Journal of Magnetic Resonance Imaging 32:2, pages 306-314.
Crossref
Swarupa Chakraborty, Deepak Kumar Kaushik, Malvika Gupta & Anirban Basu. (2010) Inflammasome signaling at the heart of central nervous system pathology. Journal of Neuroscience Research 88:8, pages 1615-1631.
Crossref
Xin-Kang Tong, Nektaria Nicolakakis, Priscilla Fernandes, Brice Ongali, Jonathan Brouillette, Rémi Quirion & Edith Hamel. (2009) Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice. Neurobiology of Disease 35:3, pages 406-414.
Crossref
Eric E. SmithSteven M. Greenberg. (2009) β-Amyloid, Blood Vessels, and Brain Function. Stroke 40:7, pages 2601-2606.
Crossref
Robert D. Bell & Berislav V. Zlokovic. (2009) Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease. Acta Neuropathologica 118:1, pages 103-113.
Crossref
Janusz Frackowiak, Anna Potempska & Bozena Mazur-Kolecka. (2009) Formation of amyloid-β oligomers in brain vascular smooth muscle cells transiently exposed to iron-induced oxidative stress. Acta Neuropathologica 117:5, pages 557-567.
Crossref
Charlotte Cordonnier & Didier Leys. 2010. Uncommon Causes of Stroke. Uncommon Causes of Stroke 455 464 .
. 2010. Uncommon Causes of Stroke. Uncommon Causes of Stroke 433 496 .
Peter M. Clifford, Gilbert Siu, Mary Kosciuk, Eli C. Levin, Venkateswar Venkataraman, Michael R. D'Andrea & Robert G. Nagele. (2008) α7 nicotinic acetylcholine receptor expression by vascular smooth muscle cells facilitates the deposition of Aβ peptides and promotes cerebrovascular amyloid angiopathy. Brain Research 1234, pages 158-171.
Crossref
Harry V. Vinters & S. Thomas Carmichael. 2015. Cognitive Neurorehabilitation. Cognitive Neurorehabilitation 360 375 .
E. Hamel, N. Nicolakakis, T. Aboulkassim, B. Ongali & X-K. Tong. (2008) Oxidative stress and cerebrovascular dysfunction in mouse models of Alzheimer's disease. Experimental Physiology 93:1, pages 116-120.
Crossref
Harry V. Vinters. (2007) Imaging cerebral microvascular amyloid. Annals of Neurology 62:3, pages 209-212.
Crossref
Sandra E. Black. (2014) Therapeutic Issues in Vascular Dementia: Studies, Designs and Approaches. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 34:S1, pages S125-S130.
Crossref
Y. I. Arshavsky. (2006) Alzheimer’s disease, brain immune privilege and memory: a hypothesis. Journal of Neural Transmission 113:11, pages 1697-1707.
Crossref
Ilene D. Auerbach & Harry V. Vinters. (2006) Effects of Anoxia and Hypoxia on Amyloid Precursor Protein Processing in Cerebral Microvascular Smooth Muscle Cells. Journal of Neuropathology & Experimental Neurology 65:6, pages 610-620.
Crossref
Bozena Mazur-Kolecka, Dennis Dickson & Janusz Frackowiak. (2006) Induction of vascular amyloidosis-β by oxidative stress depends on APOE genotype. Neurobiology of Aging 27:6, pages 804-814.
Crossref
Jordi Magrane, Rial A. Christensen, Kenneth M. Rosen, Vimal Veereshwarayya & Henry W. Querfurth. (2006) Dissociation of ERK and Akt signaling in endothelial cell angiogenic responses to β-amyloid. Experimental Cell Research 312:7, pages 996-1010.
Crossref
Xin-Kang Tong, Nektaria Nicolakakis, Ara Kocharyan & Edith Hamel. (2005) Vascular Remodeling versus Amyloid β-Induced Oxidative Stress in the Cerebrovascular Dysfunctions Associated with Alzheimer's Disease. The Journal of Neuroscience 25:48, pages 11165-11174.
Crossref
Johannes Attems. (2005) Sporadic cerebral amyloid angiopathy: pathology, clinical implications, and possible pathomechanisms. Acta Neuropathologica 110:4, pages 345-359.
Crossref
Jianting Miao, Feng Xu, Judianne Davis, Irene Otte-Höller, Marcel M. Verbeek & William E. Van Nostrand. (2005) Cerebral Microvascular Amyloid β Protein Deposition Induces Vascular Degeneration and Neuroinflammation in Transgenic Mice Expressing Human Vasculotropic Mutant Amyloid β Precursor Protein. The American Journal of Pathology 167:2, pages 505-515.
Crossref
Taro Yamashita, Yukio Ando, Shoichi Katsuragi, Masaaki Nakamura, Konen Obayashi, Katsuki Haraoka, Mitsuharu Ueda, Sun Xuguo, Sadahisa Okamoto & Makoto Uchino. (2005) Muscular amyloid angiopathy with amyloidgenic transthyretin Ser50Ile and Tyr114Cys. Muscle & Nerve 31:1, pages 41-45.
Crossref
Janusz Frackowiak, Thirasak Sukontasup, Anna Potempska & Bozena Mazur-Kolecka. (2004) Lysosomal deposition of Aβ in cultures of brain vascular smooth muscle cells is enhanced by iron. Brain Research 1002:1-2, pages 67-75.
Crossref
Edith Hamel. 2004. Acetylcholine in the Cerebral Cortex. Acetylcholine in the Cerebral Cortex 171 178 .
Annemieke A.M. Rensink, Robert M.W. de Waal, Berry Kremer & Marcel M. Verbeek. (2003) Pathogenesis of cerebral amyloid angiopathy. Brain Research Reviews 43:2, pages 207-223.
Crossref
Craig S. Atwood, Richard L. Bowen, Mark A. Smith & George Perry. (2003) Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply. Brain Research Reviews 43:1, pages 164-178.
Crossref
Ilene D Auerbach, Stanley H Sung, Zhenzhen Wang & Harry V Vinters. (2003) Smooth muscle cells and the pathogenesis of cerebral microvascular disease (“angiomyopathies”). Experimental and Molecular Pathology 74:2, pages 148-159.
Crossref
WILLIAM E. NOSTRAND, JERRY P. MELCHOR, GALINA ROMANOV, KELLY ZEIGLER & JUDIANNE DAVIS. (2002) Pathogenic Effects of Cerebral Amyloid Angiopathy Mutations in the Amyloid β-Protein Precursor. Annals of the New York Academy of Sciences 977:1, pages 258-265.
Crossref
MARION BUCKWALTER, JON-PAUL PEPPER, ROGER F. GAERTNER, DOMINIQUE VON EUW, PIERRE LACOMBE & TONY WYSS-CORAYA. (2002) Molecular and Functional Dissection of TGF-β1-Induced Cerebrovascular Abnormalities in Transgenic Mice. Annals of the New York Academy of Sciences 977:1, pages 87-95.
Crossref
K. Kobayashi, M. Hayashi, H. Nakano, Y. Fukutani, K. Sasaki, M. Shimazaki & Y. Koshino. (2002) Apoptosis of astrocytes with enhanced lysosomal activity and oligodendrocytes in white matter lesions in Alzheimer's disease. Neuropathology and Applied Neurobiology 28:3, pages 238-251.
Crossref
Zhenzhen Wang, Dafang Wu & Harry V. Vinters. (2002) Hypoxia and reoxygenation of brain microvascular smooth muscle cells in vitro: cellular responses and expression of cerebral amyloid angiopathy‐associated proteins. APMIS 110:5, pages 423-434.
Crossref
J.C. de la Torre. (2002) Alzheimer Disease as a Vascular Disorder. Stroke 33:4, pages 1152-1162.
Crossref
Johannes Rhodin & Tom Thomas. (2001) A Vascular Connection to Alzheimer's Disease. Microcirculation 8:4, pages 207-220.
Crossref
Harry V. Vinters. (2001) Cerebral amyloid angiopathy: A microvascular link between parenchymal and vascular dementia?. Annals of Neurology 49:6, pages 691-693.
Crossref
Richard Christie, Masaru Yamada, Michael Moskowitz & Bradley Hyman. (2001) Structural and Functional Disruption of Vascular Smooth Muscle Cells in a Transgenic Mouse Model of Amyloid Angiopathy. The American Journal of Pathology 158:3, pages 1065-1071.
Crossref
Panteleimon Giannakopoulos, Enikö Kövari, Gabriel Gold, Patrick R. Hof & Constantin Bouras. 2001. Functional Neurobiology of Aging. Functional Neurobiology of Aging 65 76 .
H. V. Vinters. 2001. Neuropathology. Neuropathology 51 99 .
Patricia B. Eisenhauer, Robin J. Johnson, John M. Wells, Theresa A. Davies & Richard E. Fine. (2000) Toxicity of various amyloid ? peptide species in cultured human blood-brain barrier endothelial cells: Increased toxicity of Dutch-type mutant. Journal of Neuroscience Research 60:6, pages 804-810.
Crossref
ALEX E. ROHER, YU-MIN KUO, PAMELA E. POTTER, MARK R. EMMERLING, ROBERT A. DURHAM, DOUGLAS G. WALKER, LUCIA I. SUE, WILLIAM G. HONER & THOMAS G. BEACH. (2000) Cortical Cholinergic Denervation Elicits Vascular Abeta Deposition. Annals of the New York Academy of Sciences 903:1 VASCULAR FACT, pages 366-373.
Crossref
T. WYSS-CORAY, C. LIN, D. VON EUW, E. MASLIAH, L. MUCKE & P. LACOMBE. (2000) Alzheimer's Disease-like Cerebrovascular Pathology in Transforming Growth Factor-beta1 Transgenic Mice and Functional Metabolic Correlates. Annals of the New York Academy of Sciences 903:1 VASCULAR FACT, pages 317-323.
Crossref
WILLIAM E. VAN NOSTRAND, JERRY MELCHOR, MATTHEW WAGNER & JUDIANNE DAVIS. (2000) Cerebrovascular Smooth Muscle Cell Surface Fibrillar Abeta: Alteration of the Proteolytic Environment in the Cerebral Vessel Wall. Annals of the New York Academy of Sciences 903:1 VASCULAR FACT, pages 89-96.
Crossref
Zhenzhen WangRemco NattéJudith A. BerlinerSjoerd G. van DuinenHarry V. Vinters. (2000) Toxicity of Dutch (E22Q) and Flemish (A21G) Mutant Amyloid β Proteins to Human Cerebral Microvessel and Aortic Smooth Muscle Cells. Stroke 31:2, pages 534-538.
Crossref
Nathalie Strazielle, Jean-Francois Ghersi-Egea, Jorge Ghiso, Marie-Pierre Dehouck, Blas Frangione, Clifford Patlak, Joseph Fenstermacher & Peter Gorevic. (2000) In Vitro Evidence That β-Amyloid Peptide 1–40 Diffuses Across the Blood–Brain Barrier and Affects Its Permeability. Journal of Neuropathology & Experimental Neurology 59:1, pages 29-38.
Crossref
Tony Wyss-Coray, Carol Lin, David A. Sanan, Lennart Mucke & Eliezer Masliah. (2000) Chronic Overproduction of Transforming Growth Factor-β1 by Astrocytes Promotes Alzheimer's Disease-Like Microvascular Degeneration in Transgenic Mice. The American Journal of Pathology 156:1, pages 139-150.
Crossref
Harry V. Vinters & Jean-Paul G. Vonsattel. 2000. Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders. Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders 137 155 .
Berislav V. Zlokovic, Jorge Ghiso & Blas Frangione. 2000. Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders. Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders 325 346 .
X.K. Tong & E. Hamel. (1999) Regional cholinergic denervation of cortical microvessels and nitric oxide synthase-containing neurons in Alzheimer's disease. Neuroscience 92:1, pages 163-175.
Crossref
D. Larry Sparks. 1999. Cerebral Cortex. Cerebral Cortex 733 772 .
Seiitsu Ono, Takashi Imai, Shigeru Munakata, Keiichi Takahashi, Fumio Kanda, Kazuki Hashimoto, Takahiko Yamano, Natsue Shimizu, Koichi Nagao & Mitsuo Yamauchi. (1998) Collagen abnormalities in the spinal cord from patients with amyotrophic lateral sclerosis. Journal of the Neurological Sciences 160:2, pages 140-147.
Crossref
RAJESH N. KALARIA. (1997) Cerebrovascular Degeneration Is Related to Amyloid-? Protein Deposition in Alzheimer's Disease. Annals of the New York Academy of Sciences 826:1 Cerebrovascul, pages 263-271.
Crossref
J. C. TORRE. (2006) Hemodynamic Consequences of Deformed Microvessels in the Brain in Alzheimer's Disease. Annals of the New York Academy of Sciences 826:1, pages 75-91.
Crossref
G. I. JONG, R. A. I. VOS, E. N. H. JANSEN STEUR & P. G. M. LUITEN. (1997) Cerebrovascular Hypoperfusion: A Risk Factor for Alzheimer's Disease?.. Annals of the New York Academy of Sciences 826:1 Cerebrovascul, pages 56-74.
Crossref
Leonardo PantoniJulio H. Garcia. (1997) Pathogenesis of Leukoaraiosis. Stroke 28:3, pages 652-659.
Crossref
ZHEN ZHEN WANG, OLAFUR JENSSON, LEIFUR THORSTEINSSON & HARRY V. VINTERS. (1997) Microvascular degeneration in hereditary cystatin C amyloid angiopathy of the brain. APMIS 105:1-6, pages 41-47.
Crossref
F Morin, C Crevier, G Bouvier, J.-C Lacaille & C Beaulieu. (1997) A Fixation Procedure for Ultrastructural Investigation of Synaptic Connections in Resected Human Cortex. Brain Research Bulletin 44:2, pages 205-210.
Crossref
Harry V. Vinters, Zhen Zhen Wang & Diana Lenard Secor. (2008) Brain Parenchymal and Microvascular Amyloid in Alzheimer's Disease. Brain Pathology 6:2, pages 179-195.
Crossref
Rajesh N. Kalaria. (1996) Cerebral vessels in ageing and Alzheimer's disease. Pharmacology & Therapeutics 72:3, pages 193-214.
Crossref
Rajesh N. Kalaria & Andrea B. Pax. (1995) Increased collagen content of cerebral microvessels in Alzheimer's disease. Brain Research 705:1-2, pages 349-352.
Crossref
Steven M. Greenberg, G. William Rebeck, Jean Paul G. Vonsattel, Teresa Gomez‐Isla & Bradley T. Hyman. (2004) Apolipoprotein E ϵ4 and cerebral hemorrhage associated with amyloid angiopathy. Annals of Neurology 38:2, pages 254-259.
Crossref
. 1995. Metabolic and Degenerative Diseases of the Central Nervous System. Metabolic and Degenerative Diseases of the Central Nervous System 707 850 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.