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Research Article

Chitosan-associated SLN: in vitro and ex vivo characterization of cyclosporine A loaded ophthalmic systems

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Pages 735-746 | Received 24 May 2010, Accepted 18 Aug 2010, Published online: 01 Nov 2010

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N.G.N Swamy & Z Abbas. (2014) SOLID LIPID NANOPARTICLES: EMERGING COLLOIDAL CARRIERS AS OCULAR DRUG DELIVERY SYSTEMS. INDIAN DRUGS 50:04, pages 5-25.
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Ketan HippalgaonkarGoutham R. AdelliKanchan HippalgaonkarMichael A. RepkaSoumyajit Majumdar. (2013) Indomethacin-Loaded Solid Lipid Nanoparticles for Ocular Delivery: Development, Characterization, and In Vitro Evaluation . Journal of Ocular Pharmacology and Therapeutics 29:2, pages 216-228.
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Eliana B. Souto, Joana F. Fangueiro & Rainer H. Müller. 2013. Fundamentals of Pharmaceutical Nanoscience. Fundamentals of Pharmaceutical Nanoscience 91 116 .
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Kleber L. Guimarães & Maria Inês Ré. 2011. Nanocosmetics and Nanomedicines. Nanocosmetics and Nanomedicines 101 122 .

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