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Journal of Microencapsulation
Micro and Nano Carriers
Volume 29, 2012 - Issue 7
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Research Article

Towards an inhalative in vivo application of immunomodulating gelatin nanoparticles in horse-related preformulation studies

Sebastian FuchsDepartment of Pharmacy, Pharmaceutical Technology and Biopharmacy, Ludwig Maximilians University, 81377 Munich, Germany
,
John KlierDepartment of Veterinary Medicine, Equine Clinic, Ludwig Maximilians University, 80539 Munich, Germany
,
Anna MayDepartment of Veterinary Medicine, Equine Clinic, Ludwig Maximilians University, 80539 Munich, Germany
,
Gerhard WinterDepartment of Pharmacy, Pharmaceutical Technology and Biopharmacy, Ludwig Maximilians University, 81377 Munich, Germany
,
Conrad CoesterDepartment of Pharmacy, Pharmaceutical Technology and Biopharmacy, Ludwig Maximilians University, 81377 Munich, Germany
&
Heidrun GehlenDepartment of Veterinary Medicine, Equine Clinic, Ludwig Maximilians University, 80539 Munich, Germany;Department of Veterinary Medicine, Equine Clinic, Surgery and Radiology, Freie Universität Berlin, 14163 Berlin, GermanyCorrespondence[email protected]
Pages 615-625 | Received 08 Dec 2011, Accepted 06 Feb 2012, Published online: 20 Mar 2012

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Katharina J. Geh, Madlen Hubert & Gerhard Winter. (2016) Optimisation of one-step desolvation and scale-up of gelatine nanoparticle production. Journal of Microencapsulation 33:7, pages 595-604.
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Rania M. Hathout & Mohamed K. Omran. (2016) Gelatin-based particulate systems in ocular drug delivery. Pharmaceutical Development and Technology 21:3, pages 379-386.
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Shubham Thakur, Navid Reza Shahtaghi, Manjot Kaur, Riya Shivgotra & Subheet Kumar Jain. 2023. Natural Polymeric Materials based Drug Delivery Systems in Lung Diseases. Natural Polymeric Materials based Drug Delivery Systems in Lung Diseases 235 244 .
John Klier, Sebastian Fuchs, Gerhard Winter & Heidrun Gehlen. (2022) Inhalative Nanoparticulate CpG Immunotherapy in Severe Equine Asthma: An Innovative Therapeutic Concept and Potential Animal Model for Human Asthma Treatment. Animals 12:16, pages 2087.
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Satinder Pal Kaur Malhotra & Mousa A. Alghuthaymi. 2022. Agri-Waste and Microbes for Production of Sustainable Nanomaterials. Agri-Waste and Microbes for Production of Sustainable Nanomaterials 139 163 .
Imran Moin, Largee Biswas, Md Zafaryab, Namrata Kumari, Ankita Leekha, Disha Mittal & Anita Kamra Verma. (2021) In vitro Toxico-genomics of Etoposide Loaded Gelatin Nanoparticles and Its in-vivo Therapeutic Potential: Pharmacokinetics, Biodistribution and Tumor Regression in Ehrlich Ascites Carcinoma (EAC) Mice Model. Frontiers in Nanotechnology 3.
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P. Ravi Kanth Reddy, Duvvuru Yasaswini, P. Pandu Ranga Reddy, Mohamed Zeineldin, M. J. Adegbeye & Iqbal Hyder. (2020) Applications, challenges, and strategies in the use of nanoparticles as feed additives in equine nutrition. Veterinary World 13:8, pages 1685-1696.
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Ann Kristin Barton, Tarek Shety, John Klier, Sabine Geis, Ralf Einspanier & Heidrun Gehlen. (2019) Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma. Mediators of Inflammation 2019, pages 1-7.
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Pamela Krug, Marta Bartel, Paulina Głowala, Barbara Wysocka, Ilona Mojzych, Marta Kwiatkowska, Aleksandra Skiba, Agata Wójtowicz & Maciej Mazur. 2019. Materials for Biomedical Engineering. Materials for Biomedical Engineering 59 111 .
Kelsey DeFrates, Theodore Markiewicz, Pamela Gallo, Aaron Rack, Aubrie Weyhmiller, Brandon Jarmusik & Xiao Hu. (2018) Protein Polymer-Based Nanoparticles: Fabrication and Medical Applications. International Journal of Molecular Sciences 19:6, pages 1717.
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John Klier, Sabine Geis, Jeanette Steuer, Katharina Geh, Sven Reese, Sebastian Fuchs, Ralf S. Mueller, Gerhard Winter & Heidrun Gehlen. (2017) A comparison of nanoparticulate CpG immunotherapy with and without allergens in spontaneously equine asthma‐affected horses, an animal model. Immunity, Inflammation and Disease 6:1, pages 81-96.
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Liming Yin, Carlo Yuvienco & Jin Kim Montclare. (2017) Protein based therapeutic delivery agents: Contemporary developments and challenges. Biomaterials 134, pages 91-116.
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Reena V. Saini & Reena Kumari. 2017. Metabolic Engineering for Bioactive Compounds. Metabolic Engineering for Bioactive Compounds 319 329 .
Thiago C Carvalho & Jason T McConville. (2016) The function and performance of aqueous aerosol devices for inhalation therapy. Journal of Pharmacy and Pharmacology 68:5, pages 556-578.
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Prem Prakash Sharma, Anshu Sharma & Pratima R. Solanki. 2016. Advances in Nanomaterials. Advances in Nanomaterials 365 381 .
Nityananda Sahoo, Ranjan Ku. Sahoo, Nikhil Biswas, Arijit Guha & Ketousetuo Kuotsu. (2015) Recent advancement of gelatin nanoparticles in drug and vaccine delivery. International Journal of Biological Macromolecules 81, pages 317-331.
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J. Klier, B. Lehmann, S. Fuchs, S. Reese, A. Hirschmann, C. Coester, G. Winter & H. Gehlen. (2015) Nanoparticulate CpG Immunotherapy in RAO-Affected Horses: Phase I and IIa Study. Journal of Veterinary Internal Medicine 29:1, pages 286-293.
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Wei Li, Huafeng Wei, Huafei Li, Jie Gao, Si-Shen Feng & Yajun Guo. (2014) Cancer nanoimmunotherapy using advanced pharmaceutical nanotechnology. Nanomedicine 9:16, pages 2587-2605.
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Eun Mi Lee, Deepti Singh, Dolly Singh, Soon Mo Choi, Sun Mi Zo, Seon Joo Park & Sung Soo Han. (2014) Novel Alginate-Gelatin Hybrid Nanoparticle for Drug Delivery and Tissue Engineering Applications. Journal of Nanomaterials 2014, pages 1-7.
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Ahmed O. Elzoghby. (2013) Gelatin-based nanoparticles as drug and gene delivery systems: Reviewing three decades of research. Journal of Controlled Release 172:3, pages 1075-1091.
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Matthias Wacker. (2013) Nanocarriers for intravenous injection—The long hard road to the market. International Journal of Pharmaceutics 457:1, pages 50-62.
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