Advanced search
Publication Cover
Journal of Microencapsulation
Micro and Nano Carriers
Volume 30, 2013 - Issue 1
Submit an article Journal homepage
305
Views
23
CrossRef citations to date
0
Altmetric
Research Article

Formulation of meningococcal capsular polysaccharide vaccine-loaded microparticles with robust innate immune recognition

Ruhi V. UbaleDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Mercer University, Atlanta, GA 30341, USA
,
Martin J. D'souzaDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Mercer University, Atlanta, GA 30341, USA
,
Daniel T. InfieldDepartment of Pediatrics, Division of Pulmonology, Allergy/Immunology, Cystic Fibrosis and Sleep, Emory+Children's Center for Cystic Fibrosis Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA 30322, USA
,
Nael A. McCartyDepartment of Pediatrics, Division of Pulmonology, Allergy/Immunology, Cystic Fibrosis and Sleep, Emory+Children's Center for Cystic Fibrosis Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA 30322, USA
&
Susu M. ZughaierDepartment of Pediatrics, Division of Pulmonology, Allergy/Immunology, Cystic Fibrosis and Sleep, Emory+Children's Center for Cystic Fibrosis Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA 30322, USACorrespondence[email protected]
Pages 28-41 | Received 31 Jan 2012, Accepted 23 Apr 2012, Published online: 01 Jun 2012

Citations (23)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Yizhi Qi & Christopher B. Fox. (2021) Development of thermostable vaccine adjuvants. Expert Review of Vaccines 20:5, pages 497-517.
Read now
Gaurav Kanojia, Rimko ten Have, Peter C. Soema, Henderik Frijlink, Jean-Pierre Amorij & Gideon Kersten. (2017) Developments in the formulation and delivery of spray dried vaccines. Human Vaccines & Immunotherapeutics 13:10, pages 2364-2378.
Read now
Susu M. Zughaier. (2017) Analysis of novel meningococcal vaccine formulations. Human Vaccines & Immunotherapeutics 13:7, pages 1728-1732.
Read now

Articles from other publishers (20)

Priyal Bagwe, Lotika Bajaj, Ipshita Menon, Keegan Braz Gomes, Akanksha Kale, Smital Patil, Sharon Vijayanand, Rikhav Gala, Martin J. D'Souza & Susu M. Zughaier. (2023) Gonococcal microparticle vaccine in dissolving microneedles induced immunity and enhanced bacterial clearance in infected mice. International Journal of Pharmaceutics 642, pages 123182.
Crossref
Nihal Mulla, Lipika Chablani, Ashwin C. Parenky & Martin J. D’Souza. (2023) Boosting In-Vivo Anti-Tumor Immunity with an Oral Microparticulate Breast Cancer Vaccine and Low-Dose Cyclophosphamide. Vaccines 11:3, pages 543.
Crossref
Ipshita Menon, Sang Moo Kang, Keegan Braz Gomes, Mohammad N. Uddin & Martin D'Souza. (2023) Laser-assisted intradermal delivery of a microparticle vaccine for respiratory syncytial virus induces a robust immune response. Vaccine 41:6, pages 1209-1222.
Crossref
Cordin ArpagausCordin Arpagaus. 2023. Spray Drying of Vaccines. Spray Drying of Vaccines 531 589 .
Cordin ArpagausCordin Arpagaus. 2023. Spray Drying of Vaccines. Spray Drying of Vaccines 325 530 .
Keegan Braz Gomes, Ipshita Menon, Priyal Bagwe, Lotika Bajaj, Sang-Moo Kang & Martin J. D’Souza. (2022) Enhanced Immunogenicity of an Influenza Ectodomain Matrix-2 Protein Virus-like Particle (M2e VLP) Using Polymeric Microparticles for Vaccine Delivery. Viruses 14:9, pages 1920.
Crossref
Ipshita Menon, Sang Moo Kang & Martin D'Souza. (2022) Nanoparticle formulation of the fusion protein virus like particles of respiratory syncytial virus stimulates enhanced in vitro antigen presentation and autophagy. International Journal of Pharmaceutics 623, pages 121919.
Crossref
Priyal Bagwe, Lotika Bajaj, Rikhav P. Gala, Martin J. D‘Souza & Susu M. Zughaier. (2022) Assessment of In Vitro Immunostimulatory Activity of an Adjuvanted Whole-Cell Inactivated Neisseria gonorrhoeae Microparticle Vaccine Formulation. Vaccines 10:7, pages 983.
Crossref
Valeria Trincado, Rikhav P. Gala & Javier O. Morales. (2021) Buccal and Sublingual Vaccines: A Review on Oral Mucosal Immunization and Delivery Systems. Vaccines 9:10, pages 1177.
Crossref
Laura Morelli, Laura Polito, Barbara Richichi & Federica Compostella. (2021) Glyconanoparticles as tools to prevent antimicrobial resistance. Glycoconjugate Journal 38:4, pages 475-490.
Crossref
Kendall B. Preston & Theodore W. Randolph. (2021) Stability of lyophilized and spray dried vaccine formulations. Advanced Drug Delivery Reviews 171, pages 50-61.
Crossref
Rikhav Gala, Rokon Zaman, Martin D’Souza & Susu Zughaier. (2018) Novel Whole-Cell Inactivated Neisseria Gonorrhoeae Microparticles as Vaccine Formulation in Microneedle-Based Transdermal Immunization. Vaccines 6:3, pages 60.
Crossref
Ruhi V. Ubale, Prathap Nagaraja Shastri, Carl Oettinger & Martin J. D’Souza. (2018) Pulmonary Administration of Microparticulate Antisense Oligonucleotide (ASO) for the Treatment of Lung Inflammation. AAPS PharmSciTech 19:4, pages 1908-1919.
Crossref
Rikhav P. Gala, Carmen Popescu, Gregory T. Knipp, Robyn R. McCain, Ruhi V. Ubale, Richard Addo, Tuhin Bhowmik, Christopher D. Kulczar & Martin J. D’Souza. (2016) Physicochemical and Preclinical Evaluation of a Novel Buccal Measles Vaccine. AAPS PharmSciTech 18:2, pages 283-292.
Crossref
Xiaorui Zhang, Chunhui Qi, Yan Guo, Wenxia Zhou & Yongxiang Zhang. (2016) Toll-like receptor 4-related immunostimulatory polysaccharides: Primary structure, activity relationships, and possible interaction models. Carbohydrate Polymers 149, pages 186-206.
Crossref
Rikhav P. Gala, Martin D'Souza & Susu M. Zughaier. (2016) Evaluation of various adjuvant nanoparticulate formulations for meningococcal capsular polysaccharide-based vaccine. Vaccine 34:28, pages 3260-3267.
Crossref
Susu M. Zughaier, Justin L. Kandler, Jacqueline T. Balthazar & William M. Shafer. (2015) Phosphoethanolamine Modification of Neisseria gonorrhoeae Lipid A Reduces Autophagy Flux in Macrophages. PLOS ONE 10:12, pages e0144347.
Crossref
Martin J. D’Souza, Rikhav P. Gala, Ruhi V. Ubale, Bernadette D’Souza, Trinh Phuong Vo, Ashwin C. Parenky, Nihal S. Mulla, Sucheta D’Sa, Marissa D’Souza, Kim Braz-Gomes, Nigel D’Souza, Maurizio Chiriva-Internati & Susu Zughaier. 2015. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies 89 122 .
Ruhi V. Ubale, Rikhav P. Gala, Susu M. Zughaier & Martin J. D’Souza. (2014) Induction of Death Receptor CD95 and Co-stimulatory Molecules CD80 and CD86 by Meningococcal Capsular Polysaccharide-Loaded Vaccine Nanoparticles. The AAPS Journal 16:5, pages 986-993.
Crossref
Jesus Colino, Leah Duke & Clifford M. Snapper. (2013) Noncovalent Association of Protein and Capsular Polysaccharide on Bacteria-Sized Latex Beads as a Model for Polysaccharide-Specific Humoral Immunity to Intact Gram-Positive Extracellular Bacteria. The Journal of Immunology 191:6, pages 3254-3263.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.