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Research Article

Effect of antioxidants on the stability of ONO-1301, a novel long-acting prostacyclin agonist, loaded in PLGA microspheres

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Pages 245-256 | Received 12 Mar 2012, Accepted 06 Aug 2012, Published online: 25 Oct 2012

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Mai Hazekawa, Kana Morihata, Miyako Yoshida, Yoshiki Sakai & Takahiro Uchida. (2014) The angiogenic effect of ONO-1301, a novel long-acting prostacyclin agonist loaded in PLGA microspheres prepared using different molecular weights of PLGA, in a murine sponge model. Drug Development and Industrial Pharmacy 40:11, pages 1435-1442.
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Articles from other publishers (7)

Wenping Wang, Honami Kojima, Ming Gao, Xingbin Yin, Takahiro Uchida & Jian Ni. (2023) Optimization of O/W Emulsion Solvent Evaporation Method for Itraconazole Sustained Release Microspheres. Chemical and Pharmaceutical Bulletin 71:7, pages 520-527.
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Shin Yajima, Shigeru Miyagawa, Satsuki Fukushima, Yoshiki Sakai, Kayako Isohashi, Tadashi Watabe, Hayato Ikeda, Genki Horitsugi, Akima Harada, Ryoto Sakaniwa, Jun Hatazawa & Yoshiki Sawa. (2018) A prostacyclin agonist and an omental flap increased myocardial blood flow in a porcine chronic ischemia model. The Journal of Thoracic and Cardiovascular Surgery 156:1, pages 229-241.e14.
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Sadaaki Kanayama, Takashi Kaito, Kazuma Kitaguchi, Hiroyuki Ishiguro, Kunihiko Hashimoto, Ryota Chijimatsu, Satoru Otsuru, Shota Takenaka, Takahiro Makino, Yusuke Sakai, Akira Myoui & Hideki Yoshikawa. (2018) ONO-1301 Enhances in vitro Osteoblast Differentiation and in vivo Bone Formation Induced by Bone Morphogenetic Protein. Spine 43:11, pages E616-E624.
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Hélène Pluchart, Charles Khouri, Sophie Blaise, Matthieu Roustit & Jean-Luc Cracowski. (2017) Targeting the Prostacyclin Pathway: Beyond Pulmonary Arterial Hypertension. Trends in Pharmacological Sciences 38:6, pages 512-523.
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Satsuki Fukushima, Shigeru Miyagawa, Yoshiki Sakai & Yoshiki Sawa. (2015) A sustained-release drug-delivery system of synthetic prostacyclin agonist, ONO-1301SR: a new reagent to enhance cardiac tissue salvage and/or regeneration in the damaged heart. Heart Failure Reviews 20:4, pages 401-413.
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Rachit Ohri, Jeffrey Chi-Fei Wang, Phillip D. Blaskovich, Lan N. Pham, Daniel S. Costa, Gary A. Nichols, William P. Hildebrand, Nelson L. Scarborough, Clifford J. Herman & Gary R. Strichartz. (2013) Inhibition by Local Bupivacaine-Releasing Microspheres of Acute Postoperative Pain from Hairy Skin Incision. Anesthesia & Analgesia 117:3, pages 717-730.
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Takahiro Uchida, Mai Hazekawa, Miyako Yoshida, Kunio Matsumoto & Yoshiki Sakai. (2013) A Novel Long-Acting Prostacyclin Agonist (ONO-1301) With an Angiogenic Effect: Promoting Synthesis of Hepatocyte Growth Factor and Increasing Cyclic AMP Concentration via IP-Receptor Signaling. Journal of Pharmacological Sciences 123:4, pages 392-401.
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