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Journal of Microencapsulation
Micro and Nano Carriers
Volume 30, 2013 - Issue 7
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Research Article

Wheat germ agglutinin-functionalised crosslinked polyelectrolyte microparticles for local colon delivery of 5-FU: in vitro efficacy and in vivo gastrointestinal distribution

Marija Glavas-DodovInstitute of Pharmaceutical Technology, Faculty of Pharmacy, University “Ss Cyril and Methodius”, Vodnjanska 17, P.O. Box 36, 1000 Skopje, MacedoniaCorrespondence[email protected]
,
Bente SteffansenDepartment of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen 2100, Denmark
,
Maja S. CrcarevskaInstitute of Pharmaceutical Technology, Faculty of Pharmacy, University “Ss Cyril and Methodius”, Vodnjanska 17, P.O. Box 36, 1000 Skopje, Macedonia
,
Nikola GeskovskiInstitute of Pharmaceutical Technology, Faculty of Pharmacy, University “Ss Cyril and Methodius”, Vodnjanska 17, P.O. Box 36, 1000 Skopje, Macedonia
,
Simona DimchevskaInstitute of Pharmaceutical Technology, Faculty of Pharmacy, University “Ss Cyril and Methodius”, Vodnjanska 17, P.O. Box 36, 1000 Skopje, Macedonia
,
Sonja KuzmanovskaInstitute of Pathophysiology and Nuclear Medicine, Medical Faculty, University “Ss Cyril and Methodius”, Vodnjanska 17, 1000 Skopje, Macedonia
&
Katerina GoracinovaInstitute of Pharmaceutical Technology, Faculty of Pharmacy, University “Ss Cyril and Methodius”, Vodnjanska 17, P.O. Box 36, 1000 Skopje, Macedonia
 show all
Pages 643-656 | Received 03 Sep 2012, Accepted 07 Jan 2013, Published online: 02 Apr 2013

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Shangyong Li, Hui Zhang, Kaiwei Chen, Mengfei Jin, Son Hai Vu, Samil Jung, Ningning He, Zhou Zheng & Myeong-Sok Lee. (2022) Application of chitosan/alginate nanoparticle in oral drug delivery systems: prospects and challenges. Drug Delivery 29:1, pages 1142-1149.
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Hock Ing Chiu & Vuanghao Lim. (2021) Wheat Germ Agglutinin-Conjugated Disulfide Cross-Linked Alginate Nanoparticles as a Docetaxel Carrier for Colon Cancer Therapy. International Journal of Nanomedicine 16, pages 2995-3020.
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Aisha Sethi, Mahmood Ahmad, Tayyaba Huma & Waqas Ahmad. (2021) Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity. Drug Delivery 28:1, pages 1569-1584.
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Umme Hani, Yogish Kumar Honnavalli, M. Yasmin Begum, Sabina Yasmin, Riyaz Ali M. Osmani & Mohammad Yousuf Ansari. (2021) Colorectal cancer: A comprehensive review based on the novel drug delivery systems approach and its management. Journal of Drug Delivery Science and Technology 63, pages 102532.
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Aline Martins dos Santos, Suzana Gonçalves Carvalho, Andréia Bagliotti Meneguin, Rafael Miguel Sábio, Maria Palmira Daflon Gremião & Marlus Chorilli. (2021) Oral delivery of micro/nanoparticulate systems based on natural polysaccharides for intestinal diseases therapy: Challenges, advances and future perspectives. Journal of Controlled Release 334, pages 353-366.
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Xiaoying Duan, Yuanfang Cheng, Feng Sang, Lina Liu, Zhen Liu, Lin Cui & Haixia Li. (2020) Enhanced Targeting Function and Anti-colon Cancer Efficacy by Wheat Germ Agglutinin-modified Nanoparticles for Matrine Delivery. International Journal of Pharmacology 16:6, pages 470-478.
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Sundeep Chaurasia, Ravi R Patel, Prasad Vure & Brahmeshwar Mishra. (2017) Oral naringenin nanocarriers: Fabrication, optimization, pharmacokinetic and chemotherapeutic efficacy assessments. Nanomedicine 12:11, pages 1243-1260.
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Yansha Meng, Xucheng Hou, Jiongxi Lei, Mengmeng Chen, Shuangchen Cong, Yuanyuan Zhang, Weiming Ding, Guiling Li & Xinru Li. (2015) Multi-functional Liposomes Enhancing Target and Antibacterial Immunity for Antimicrobial and Anti-Biofilm Against Methicillin-Resistant Staphylococcus aureus. Pharmaceutical Research 33:3, pages 763-775.
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Arvind Gulbake. (2016) Insight to drug delivery aspects for colorectal cancer. World Journal of Gastroenterology 22:2, pages 582.
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Vesna Petrovska-Jovanovska, Nikola Geskovski, Maja Simonoska Crcarevska, Oya Memed, Gjorgji Petruševski, Marina Chachorovska, Marija Petrusevska, Ana Poceva-Panovska, Kristina Mladenovska, Sonja Ugarkovic & Marija Glavas-Dodov. (2015) Formulation and characterization of ORMOSIL particles loaded with budesonide for local colonic delivery. International Journal of Pharmaceutics 484:1-2, pages 75-84.
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