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Journal of Microencapsulation
Micro and Nano Carriers
Volume 30, 2013 - Issue 7
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Research Article

Solubilization of flurbiprofen into aptamer-modified PEG–PLA micelles for targeted delivery to brain-derived endothelial cells in vitro

Chaofeng MuDivision of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati Cincinnati, OHUSA
,
Nimita DaveDivision of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati Cincinnati, OHUSA
,
Jing HuDivision of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati Cincinnati, OHUSA
,
Pankaj DesaiDivision of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati Cincinnati, OHUSA
,
Giovanni PaulettiDivision of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati Cincinnati, OHUSA
,
Shuhua BaiDepartment of Basic Pharmaceutical Sciences, School of Pharmacy, Husson University Bangor, MEUSA
&
Jiukuan HaoDivision of Pharmaceutical Sciences, James L. Winkle College of Pharmacy, University of Cincinnati Cincinnati, OHUSACorrespondence[email protected]
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Pages 701-708 | Received 15 Aug 2012, Accepted 11 Feb 2013, Published online: 21 Mar 2013

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Jie Li, Jiaqian Zhao, Tiantian Tan, Mengmeng Liu, Zhaowu Zeng, Yiying Zeng, Lele Zhang, Chaomei Fu, Dajing Chen & Tian Xie. (2020) Nanoparticle Drug Delivery System for Glioma and Its Efficacy Improvement Strategies: A Comprehensive Review. International Journal of Nanomedicine 15, pages 2563-2582.
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Narayanan Kasinathan, Hitesh V. Jagani, Angel Treasa Alex, Subrahmanyam M. Volety & J. Venkata Rao. (2015) Strategies for drug delivery to the central nervous system by systemic route. Drug Delivery 22:3, pages 243-257.
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Tianzhi Yang, Tracy Bantegui, Kaitlynn Pike, Raymond Bloom, Roger Phipps & Shuhua Bai. (2014) In vitro evaluation of optimized liposomes for delivery of small interfering RNA. Journal of Liposome Research 24:4, pages 270-279.
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Laís Ribovski, Naomi M. Hamelmann & Jos M. J. Paulusse. (2021) Polymeric Nanoparticles Properties and Brain Delivery. Pharmaceutics 13:12, pages 2045.
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Aditi Singh. (2021) Nanomedicines: Recent Progress, Impact and Challenges in Applications. Asian Journal of Chemistry 33:11, pages 2561-2578.
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Salah M. Tawfik, Shavkatjon Azizov, Mohamed R. Elmasry, Mirkomil Sharipov & Yong-Ill Lee. (2020) Recent Advances in Nanomicelles Delivery Systems. Nanomaterials 11:1, pages 70.
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Muhammad Bilal, Mahmood Barani, Fakhara Sabir, Abbas Rahdar & George Z. Kyzas. (2020) Nanomaterials for the treatment and diagnosis of Alzheimer's disease: An overview. NanoImpact 20, pages 100251.
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Shafq Al-azzawi, Dhafir Masheta, Anna Guildford, Gary Phillips & Matteo Santin. (2020) A Peptide-Based Nanocarrier for an Enhanced Delivery and Targeting of Flurbiprofen into the Brain for the Treatment of Alzheimer’s Disease: An In Vitro Study. Nanomaterials 10:8, pages 1590.
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Alina Eilers, Sandra Witt & Johanna Walter. 2020. Aptamers in Biotechnology. Aptamers in Biotechnology 161 193 .
Kasper Bendix Johnsen, Annette Burkhart, Louiza Bohn Thomsen, Thomas Lars Andresen & Torben Moos. (2019) Targeting the transferrin receptor for brain drug delivery. Progress in Neurobiology 181, pages 101665.
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Xiaoqian Niu, Jiejian Chen & Jianqing Gao. (2019) Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances. Asian Journal of Pharmaceutical Sciences 14:5, pages 480-496.
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Somayeh Vandghanooni, Morteza Eskandani, Jaleh Barar & Yadollah Omidi. (2018) Bispecific therapeutic aptamers for targeted therapy of cancer: a review on cellular perspective. Journal of Molecular Medicine 96:9, pages 885-902.
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Hassan A. Almoustafa, Mohammed A. Alshawsh & Zamri Chik. (2017) Technical aspects of preparing PEG-PLGA nanoparticles as carrier for chemotherapeutic ‎agents by nanoprecipitation method. International Journal of Pharmaceutics 533:1, pages 275-284.
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Reham S. Elezaby, Heba A. Gad, Abdelkader A. Metwally, Ahmed S. Geneidi & Gehanne A. Awad. (2017) Self-assembled amphiphilic core-shell nanocarriers in line with the modern strategies for brain delivery. Journal of Controlled Release 261, pages 43-61.
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Mary Joseph, Hoang M. Trinh & Ashim K. Mitra. 2017. Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices. Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices 145 167 .
Hoang M. Trinh, Mary Joseph, Kishore Cholkar, Ranjana Mitra & Ashim K. Mitra. 2017. Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices. Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices 45 58 .
Silvia Catuogno, Carla Esposito & Vittorio de Franciscis. (2016) Aptamer-Mediated Targeted Delivery of Therapeutics: An Update. Pharmaceuticals 9:4, pages 69.
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Iolanda Fotticchia, Daniela Guarnieri, Teresa Fotticchia, Andrea Patrizia Falanga, Raffaele Vecchione, Concetta Giancola & Paolo Antonio Netti. (2016) Energetics of ligand-receptor binding affinity on endothelial cells: An in vitro model. Colloids and Surfaces B: Biointerfaces 144, pages 250-256.
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Hunho Jo & Changill Ban. (2016) Aptamer–nanoparticle complexes as powerful diagnostic and therapeutic tools. Experimental & Molecular Medicine 48:5, pages e230-e230.
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Yuyang Kuang, Xutao Jiang, Yu Zhang, Yifei Lu, Haojun Ma, Yubo Guo, Yujie Zhang, Sai An, Jianfeng Li, Lisha Liu, Yinhao Wu, Jianying Liang & Chen Jiang. (2016) Dual Functional Peptide-Driven Nanoparticles for Highly Efficient Glioma-Targeting and Drug Codelivery. Molecular Pharmaceutics 13:5, pages 1599-1607.
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Francesca Maestrelli, Marco Bragagni & Paola Mura. (2016) Advanced formulations for improving therapies with anti-inflammatory or anaesthetic drugs: A review. Journal of Drug Delivery Science and Technology 32, pages 192-205.
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Feng Jiang, Biao Liu, Jun Lu, Fangfei Li, Defang Li, Chao Liang, Lei Dang, Jin Liu, Bing He, Shaikh Badshah, Cheng Lu, Xiaojuan He, Baosheng Guo, Xiao-Bing Zhang, Weihong Tan, Aiping Lu & Ge Zhang. (2015) Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems. International Journal of Molecular Sciences 16:10, pages 23784-23822.
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Erin M. McConnellMatthew R. HolahanMaria C. DeRosa. (2014) Aptamers as Promising Molecular Recognition Elements for Diagnostics and Therapeutics in the Central Nervous System. Nucleic Acid Therapeutics 24:6, pages 388-404.
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Jiehua Zhou & John J. Rossi. (2014) Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy. Molecular Therapy - Nucleic Acids 3, pages e169.
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