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Research Article

Solid self-nanoemulsifying drug delivery system (SNEDDS) for enhanced oral bioavailability of poorly water-soluble tacrolimus: physicochemical characterisation and pharmacokinetics

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Pages 503-510 | Received 11 Nov 2014, Accepted 04 May 2015, Published online: 16 Jun 2015

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Ahmed Alaa Kassem, Sameh Hosam Abd El-Alim, Asmaa Mohamed Salman, Mona Arafa Mohammed, Nabila Salah Hassan & Souad Eisawy El-Gengaihi. (2020) Improved hepatoprotective activity of Beta vulgaris L. leaf extract loaded self-nanoemulsifying drug delivery system (SNEDDS): in vitro and in vivo evaluation. Drug Development and Industrial Pharmacy 46:10, pages 1589-1603.
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Kyeong Soo Kim, Eun Su Yang, Dong Shik Kim, Dong Wuk Kim, Hye Hyun Yoo, Chul Soon Yong, Yu Seok Youn, Kyung Taek Oh, Jun-Pil Jee, Jong Oh Kim, Sung Giu Jin & Han Gon Choi. (2017) A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol. Drug Delivery 24:1, pages 1018-1025.
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Anuj Garg & Rajat Garg. (2022) Current advances in colloidal based delivery systems for Tacrolimus. Journal of Drug Delivery Science and Technology 68, pages 103108.
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Khaled M. Hosny, Nabil A. Alhakamy, Maeen A. Almodhwahi, Mallesh Kurakula, Alshaimaa M. Almehmady & Samar S. Elgebaly. (2020) Self-Nanoemulsifying System Loaded with Sildenafil Citrate and Incorporated within Oral Lyophilized Flash Tablets: Preparation, Optimization, and In Vivo Evaluation. Pharmaceutics 12:11, pages 1124.
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Qiuyang Dai, Peiyan Zhang, Yilan Jin, Mi Tang, Mengling Shen, Shujun Xu, Susu Huang & Yong Chen. (2020) Using Self-Nanoemulsifying System to Improve Oral Bioavailability of a Pediatric Antiepileptic Agent Stiripentol: Formulation and Pharmacokinetics Studies. AAPS PharmSciTech 21:5.
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Yasir A. Al-Amodi, Khaled M Hosny, Waleed S. Alharbi, Martin K. Safo & Khalid M El-Say. (2020) Investigating the Potential of Transmucosal Delivery of Febuxostat from Oral Lyophilized Tablets Loaded with a Self-Nanoemulsifying Delivery System. Pharmaceutics 12:6, pages 534.
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Eun-Sol Ha, Seon-Kwang Lee, Du Hyung Choi, Seong Hoon Jeong, Sung-Joo Hwang & Min-Soo Kim. (2019) Application of diethylene glycol monoethyl ether in solubilization of poorly water-soluble drugs. Journal of Pharmaceutical Investigation 50:3, pages 231-250.
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Jung Hyun Cho & Han-Gon Choi. (2020) Development of novel tenofovir disoproxil phosphate salt with stability enhancement and bioequivalence to the commercial tenofovir disoproxil fumarate salt in rats and beagle dogs. International Journal of Pharmaceutics 576, pages 118957.
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Kim, Kim, Lim, Kim, Yong, Choi & Jin. (2019) Comparison of 1-Palmitoyl-2-Linoleoyl-3-Acetyl-Rac-Glycerol-Loaded Self-Emulsifying Granule and Solid Self-Nanoemulsifying Drug Delivery System: Powder Property, Dissolution and Oral Bioavailability. Pharmaceutics 11:8, pages 415.
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Abid Mehmood Yousaf, Usman Rashid Malik, Yasser Shahzad, Tariq Mahmood & Talib Hussain. (2019) Silymarin-laden PVP-PEG polymeric composite for enhanced aqueous solubility and dissolution rate: Preparation and in vitro characterization. Journal of Pharmaceutical Analysis 9:1, pages 34-39.
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Li Li, Chun Hui Zhou & Zhi Ping Xu. 2019. Nanocarriers for Drug Delivery. Nanocarriers for Drug Delivery 421 449 .
Barnabás Palcsó & Romána Zelkó. (2018) Different types, applications and limits of enabling excipients of pharmaceutical dosage forms. Drug Discovery Today: Technologies 27, pages 21-39.
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Divya Dheer, Jyoti, Prem N. Gupta & Ravi Shankar. (2018) Tacrolimus: An updated review on delivering strategies for multifarious diseases. European Journal of Pharmaceutical Sciences 114, pages 217-227.
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Taotao Huo, Chun Tao, Minxin Zhang, Qinghong Liu, Bing Lin, Zhihong Liu, Jialiang Zhang, Meijing Zhang, Haiyue Yang, Jue Wu, Xinrong Sun, Qian Zhang & Hongtao Song. (2018) Preparation and comparison of tacrolimus-loaded solid dispersion and self-microemulsifying drug delivery system by in vitro/in vivo evaluation. European Journal of Pharmaceutical Sciences 114, pages 74-83.
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Jong Hyuck Park, Dong Shik Kim, Omer Mustapha, Abid Mehmood Yousaf, Jung Suk Kim, Dong Wuk Kim, Chul Soon Yong, Yu Seok Youn, Kyung Taek Oh, Soo-Jeong Lim, Jong Oh Kim & Han-Gon Choi. (2018) Comparison of a revaprazan-loaded solid dispersion, solid SNEDDS and inclusion compound: Physicochemical characterisation and pharmacokinetics. Colloids and Surfaces B: Biointerfaces 162, pages 420-426.
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Kunal Patel, Carl Atkinson, Danh Tran & Satish N. Nadig. (2017) Nanotechnological Approaches to Immunosuppression and Tolerance Induction. Current Transplantation Reports 4:2, pages 159-168.
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