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Journal of Microencapsulation
Micro and Nano Carriers
Volume 9, 1992 - Issue 3
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Research Article

In vivo distribution and antitumour activity of liposomal 3′,5′-O-dipalmitoyl-5-fluoro-2′-deoxyuridine

M. Van Borssum Waalkes Laboratory of Physiological Chemistry, University of Groningen, Bloemsingel 10, 9712 KZ, Groningen, The Netherlands
,
I. Fichtner Zentralinstitut für Krebsforschung, Robert Rössle Institut, Lindenbergerweg 80, 1115, Berlin-Buch, Germany
,
B. Dontje Laboratory of Physiological Chemistry, University of Groningen, Bloemsingel 10, 9712 KZ, Groningen, The Netherlands
,
M. Lemm Zentralinstitut für Krebsforschung, Robert Rössle Institut, Lindenbergerweg 80, 1115, Berlin-Buch, Germany
,
M. Becker Zentralinstitut für Krebsforschung, Robert Rössle Institut, Lindenbergerweg 80, 1115, Berlin-Buch, Germany
,
D. Arndt Zentralinstitut für Krebsforschung, Robert Rössle Institut, Lindenbergerweg 80, 1115, Berlin-Buch, Germany
&
G. L. Scherphof Laboratory of Physiological Chemistry, University of Groningen, Bloemsingel 10, 9712 KZ, Groningen, The Netherlands
 show all
Pages 335-346 | Received 23 Jul 1991, Accepted 29 Sep 1991, Published online: 27 Sep 2008

Citations (11)

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Read on this site (2)

Gerrit L. Scherphof, A.A.M. Kamps & Gerben A. Koning. (1997) In vivo targeting of surface-modified liposomes to metastatically growing colon carcinoma cells and sinusoidal endothelial cells in the rat liver. Journal of Liposome Research 7:4, pages 419-432.
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Gerrit L. Scherphof & Marjan Van Borssum Waalkes. (1994) Release of Active Drug from Intracellular Liposomal Prodrug Depots in Macrophages Controlled by Liposome Composition. Journal of Liposome Research 4:1, pages 427-437.
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Articles from other publishers (9)

Rea D. Signorell, Paola Luciani, Davide Brambilla & Jean-Christophe Leroux. (2018) Pharmacokinetics of lipid-drug conjugates loaded into liposomes. European Journal of Pharmaceutics and Biopharmaceutics 128, pages 188-199.
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Enrico Mastrobattista, Gerben A Koning & Gert Storm. (1999) Immunoliposomes for the targeted delivery of antitumor drugs. Advanced Drug Delivery Reviews 40:1-2, pages 103-127.
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G A Koning, A Gorter, G L Scherphof & J A A M Kamps. (1999) Antiproliferative effect of immunoliposomes containing 5-fluorodeoxyuridine-dipalmitate on colon cancer cells. British Journal of Cancer 80:11, pages 1718-1725.
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Monica Gulati, Manish Grover, Saranjit Singh & Mandip Singh. (1998) Lipophilic drug derivatives in liposomes. International Journal of Pharmaceutics 165:2, pages 129-168.
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Paola Crosasso, Paola Brusa, Franco Dosio, Silvia Arpicco, Donatella Pacchioni, Francis Schuberî & Luigi Cattel. (1997) Antitumoral Activity of Liposomes and Immunoliposomes Containing 5-Fluorouridine Prodrugs. Journal of Pharmaceutical Sciences 86:7, pages 832-839.
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Jan A.A.M Kamps, Pieter J Swart, Henriëtte W.M Morselt, Rudi Pauwels, Marie-Pierre De Béthune, Erik De Clercq, Dirk K.F Meijer & Gerrit L Scherphof. (1996) Preparation and characterization of conjugates of (modified) human serum albumin and liposomes: drug carriers with an intrinsic anti-HIV activity. Biochimica et Biophysica Acta (BBA) - Biomembranes 1278:2, pages 183-190.
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Atsuhide Mori, Stephen J. Kennel, Marjan van Borssum Waalkes, Gerrit L. Scherphof & Leaf Huang. (1995) Characterization of organ-specific immunoliposomes for delivery of 3′,5′-O-dipalmitoyl-5-fluoro-2′-deoxyuridine in a mouse lung-metastasis model. Cancer Chemotherapy and Pharmacology 35:6, pages 447-456.
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Marjan van Borssum Waalkes, Mieke van Galen, Henriëtte Morselt, Brigitte Sternberg & Gerrit L. Scherphof. (1993) In-vitro stability and cytostatic activity of liposomal formulations of 5-fluoro-2′-deoxyuridine and its diacylated derivatives. Biochimica et Biophysica Acta (BBA) - Biomembranes 1148:1, pages 161-172.
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Marjan van Borssum Waalkes, Folkert Kuipers, Rick Havinga & Gerrit L. Scherphof. (1993) Conversion of liposomal 5-fluoro-2′-deoxyuridine and its dipalmitoyl derivative to bile acid conjugates of α-fluoro-β-alanine and their excretion into rat bile. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1176:1-2, pages 43-50.
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