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Journal of Microencapsulation
Micro and Nano Carriers
Volume 13, 1996 - Issue 1
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Research Article

Preparation, characterization and in vitro drug release of poly-∈-caprolactone and hydroxypropyl methylcellulose phthalate ketoprofen loaded microspheres

M. Guzmán Dpto. Farmacia y Tecnología Farmacéutica, Universidad de Alcalá de Henares Ctra, Madrid-Barcelona km. 33.600.28871 Alcalá de Henare, (Madrid), Spain
,
J. Molpeceres Dpto. Farmacia y Tecnología Farmacéutica, Universidad de Alcalá de Henares Ctra, Madrid-Barcelona km. 33.600.28871 Alcalá de Henare, (Madrid), Spain
,
F. García Dpto. Farmacia y Tecnología Farmacéutica, Universidad de Alcalá de Henares Ctra, Madrid-Barcelona km. 33.600.28871 Alcalá de Henare, (Madrid), Spain
&
M. R. Aberturas Dpto. Farmacia y Tecnología Farmacéutica, Universidad de Alcalá de Henares Ctra, Madrid-Barcelona km. 33.600.28871 Alcalá de Henare, (Madrid), Spain
Pages 25-39 | Received 05 Apr 1994, Accepted 20 Jan 1995, Published online: 27 Sep 2008

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Sergio Miguel Espinoza, Harshal Indrabhan Patil, Eduardo San Martin Martinez, Rocio Casañas Pimentel & Pradum Pundlikrao Ige. (2020) Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer. International Journal of Polymeric Materials and Polymeric Biomaterials 69:2, pages 85-126.
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Abhalaxmi Singh, Ranjita Misra, Chandana Mohanty & SanjeebK. Sahoo. (2010) Applications of Nanotechnology in Vaccine Delivery. International Journal of Green Nanotechnology: Biomedicine 2:1, pages B25-B45.
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Raghavendra V. Kulkarni & Biswanath Sa. (2008) Enteric delivery of ketoprofen through functionally modified poly(acrylamide-grafted-xanthan)-based pH-sensitive hydrogel beads: Preparation, in vitro and in vivo evaluation. Journal of Drug Targeting 16:2, pages 167-177.
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Colin J. Thompson, Denise Hansford, Sean Higgins, Gillian A. Hutcheon, Chris Rostron & Dale L. Munday. (2006) Enzymatic synthesis and evaluation of new novel ω-pentadecalactone polymers for the production of biodegradable microspheres. Journal of Microencapsulation 23:2, pages 213-226.
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J. Molpeceres, M. R. Aberturas, M. Chacón, L. Berges & M. Guzmán. (1997) Stability of cyclosporine-loaded poly-X-caprolactone nanoparticles. Journal of Microencapsulation 14:6, pages 777-787.
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A. Esquisabelr, M. Hernáandez, M. Igartuaa, R. Gascóan, B. Calvo & J. L. Pedraz. (1997) Production of BCG alginate-PLL microcapsules by emulsification/internal gelation. Journal of Microencapsulation 14:5, pages 627-638.
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Tony L. Whateley. (1996) Literature Alerts. Drug Delivery 3:4, pages 309-320.
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Articles from other publishers (17)

Ka Yee Wan, Jingwen Weng, Si Nga Wong, Philip Chi Lip Kwok, Shing Fung Chow & Albert Hee Lum Chow. (2020) Converting nanosuspension into inhalable and redispersible nanoparticles by combined in-situ thermal gelation and spray drying. European Journal of Pharmaceutics and Biopharmaceutics 149, pages 238-247.
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Leticia Goimil, Mara E.M. Braga, Ana M.A. Dias, José L. Gómez-Amoza, Angel Concheiro, Carmen Alvarez-Lorenzo, Hermínio C. de Sousa & Carlos A. García-González. (2017) Supercritical processing of starch aerogels and aerogel-loaded poly(ε-caprolactone) scaffolds for sustained release of ketoprofen for bone regeneration. Journal of CO2 Utilization 18, pages 237-249.
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S.A. Chew, V.A. Hinojosa & M.A. Arriaga. 2017. Bioresorbable Polymers for Biomedical Applications. Bioresorbable Polymers for Biomedical Applications 229 264 .
Hernán E. Romeo, Mónica Cameo, María V. Choren & María A. Fanovich. (2011) Functionalized bridged silsesquioxane-based nanostructured microspheres: ultrasound-assisted synthesis and in vitro cytotoxicity characterization. Journal of Materials Science: Materials in Medicine 22:4, pages 935-943.
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Seitaro Kamiya, Takurou Kurita, Atsuo Miyagishima, Shigeru Itai & Masayuki Arakawa. (2010) Physical properties of griseofulvin-lipid nanoparticles in suspension and their novel interaction mechanism with saccharide during freeze-drying. European Journal of Pharmaceutics and Biopharmaceutics 74:3, pages 461-466.
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E.T. BARAN & R.L. REIS. 2008. Natural-Based Polymers for Biomedical Applications. Natural-Based Polymers for Biomedical Applications 597 623 .
Sean M. Hartig, Rachel R. Greene, Mikhail M. Dikov, Ales Prokop & Jeffrey M. Davidson. (2007) Multifunctional Nanoparticulate Polyelectrolyte Complexes. Pharmaceutical Research 24:12, pages 2353-2369.
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Sean M. Hartig, Gianluca Carlesso, Jeffrey M. Davidson & Ales Prokop. (2006) Development of Improved Nanoparticulate Polyelectrolyte Complex Physicochemistry by Nonstoichiometric Mixing of Polyions with Similar Molecular Weights. Biomacromolecules 8:1, pages 265-272.
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Karen Chou & Robert O. Wright. (2006) Phthalates in food and medical devices. Journal of Medical Toxicology 2:3, pages 126-135.
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Anne-Marie Le Ray, Hélène Gautier, Marie-Katel Laty, Guy Daculsi, Christian Merle, Cédric Jacqueline, Antoine Hamel & Jocelyne Caillon. (2005) In Vitro and In Vivo Bactericidal Activities of Vancomycin Dispersed in Porous Biodegradable Poly(ε-Caprolactone) Microparticles. Antimicrobial Agents and Chemotherapy 49:7, pages 3025-3027.
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Da-Qing Wu, Xiang-Zheng Zhang & Chih-Chang Chu. (2005) Functionalized Three-Arm Poly(??-Caprolactone) Maleic Acid Microspheres for Controlled Protein Release. American Journal of Drug Delivery 3:4, pages 253-267.
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V.R. Sinha, K. Bansal, R. Kaushik, R. Kumria & A. Trehan. (2004) Poly-ϵ-caprolactone microspheres and nanospheres: an overview. International Journal of Pharmaceutics 278:1, pages 1-23.
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Samaresh Ghosh. (2019) Recent research and development in synthetic polymer-based drug delivery systems. Journal of Chemical Research 2004:4, pages 241-246.
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A.-M Le Ray, S Chiffoleau, P Iooss, G Grimandi, A Gouyette, G Daculsi & C Merle. (2003) Vancomycin encapsulation in biodegradable poly(ε-caprolactone) microparticles for bone implantation. Influence of the formulation process on size, drug loading, in vitro release and cytocompatibility. Biomaterials 24:3, pages 443-449.
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Tommy Tarvainen, Teija Karjalainen, Minna Malin, Kristiina Peräkorpi, Jukka Tuominen, Jukka Seppälä & Kristiina Järvinen. (2002) Drug release profiles from and degradation of a novel biodegradable polymer, 2,2-bis(2-oxazoline) linked poly(ε-caprolactone). European Journal of Pharmaceutical Sciences 16:4-5, pages 323-331.
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P Iooss, A.-M Le Ray, G Grimandi, G Daculsi & C Merle. (2001) A new injectable bone substitute combining poly(ε-caprolactone) microparticles with biphasic calcium phosphate granules. Biomaterials 22:20, pages 2785-2794.
Crossref
Wen-Jen Lin, Douglas R. Flanagan & Robert J. Linhardt. (1999) A novel fabrication of poly(ε-caprolactone) microspheres from blends of poly(ε-caprolactone) and poly(ethylene glycol)s. Polymer 40:7, pages 1731-1735.
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