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Research Article

Formulation of BCNU-loaded microspheres: Influence of drug stability and solubility on the design of the microencapsulation procedure

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Pages 41-51 | Received 03 May 1994, Accepted 10 Oct 1994, Published online: 27 Sep 2008

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Vandana Kharb, Vikas Anand Saharan, Kapil Dev, Hemant Jadhav & Suresh Purohit. (2014) Formulation, evaluation and 32 full factorial design-based optimization of ondansetron hydrochloride incorporated taste masked microspheres. Pharmaceutical Development and Technology 19:7, pages 839-852.
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María Esther Gil-Alegre, Isabel González-Álvarez, Laura Gutiérrez-Paúls & Ana Isabel Torres-Suárez. (2008) Three weeks release BCNU loaded hydrophilic-PLGA microspheres for interstitial chemotherapy: Development and activity against human glioblastoma cells. Journal of Microencapsulation 25:8, pages 561-568.
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Philippe Menei, Claudia Montero-Menei, Marie-Claire Venier & Jean-Pierre Benoit. (2005) Drug delivery into the brain using poly(lactide-co-glycolide) microspheres. Expert Opinion on Drug Delivery 2:2, pages 363-376.
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Tony L. Whateley. (1996) Literature Alerts. Drug Delivery 3:4, pages 309-320.
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Ruchi M. Shah & Anil P. D’mello. (2008) Strategies to maximize the encapsulation efficiency of phenylalanine ammonia lyase in microcapsules. International Journal of Pharmaceutics 356:1-2, pages 61-68.
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Brian C. Anderson, Aurelia Amanda & Surya K. Mallapragada. 2002. Methods of Tissue Engineering. Methods of Tissue Engineering 835 839 .
Rocio Herrero-Vanrell & Miguel F Refojo. (2001) Biodegradable microspheres for vitreoretinal drug delivery. Advanced Drug Delivery Reviews 52:1, pages 5-16.
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Jean-Pierre Benoit, Nathalie Faisant, Marie-Claire Venier-Julienne & Philippe Menei. (2000) Development of microspheres for neurological disorders: From basics to clinical applications. Journal of Controlled Release 65:1-2, pages 285-296.
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Philippe Menei, Marie-Claire Venier, Erik Gamelin, Jean-Paul Saint-Andr�, Ghassan Hayek, Eric Jadaud, Dominique Fournier, Philippe Mercier, Gilles Guy & Jean-Pierre Benoit. (1999) Local and sustained delivery of 5-fluorouracil from biodegradable microspheres for the radiosensitization of glioblastoma. Cancer 86:2, pages 325-330.
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Wen-Jen Lin, Douglas R. Flanagan & Robert J. Linhardt. (1999) A novel fabrication of poly(ε-caprolactone) microspheres from blends of poly(ε-caprolactone) and poly(ethylene glycol)s. Polymer 40:7, pages 1731-1735.
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T Painbeni, M.C Venier-Julienne & J.P Benoit. (1998) Internal morphology of poly(d,l-lactide-co-glycolide) BCNU-loaded microspheres. Influence on drug stability. European Journal of Pharmaceutics and Biopharmaceutics 45:1, pages 31-39.
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