167
Views
54
CrossRef citations to date
0
Altmetric
Research Article

New strategies for the microencapsulation of tetanus vaccine

, , , &
Pages 299-318 | Received 10 Dec 1996, Accepted 14 Mar 1997, Published online: 27 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Dylan A. Hendy, Alex Haven, Eric M. Bachelder & Kristy M. Ainslie. (2023) Preclinical developments in the delivery of protein antigens for vaccination. Expert Opinion on Drug Delivery 20:3, pages 367-384.
Read now
Ching Mien Oh, Qiyun Guo, Paul Wan Sia Heng & Lai Wah Chan. (2014) Spray-congealed microparticles for drug delivery – an overview of factors influencing their production and characteristics. Expert Opinion on Drug Delivery 11:7, pages 1047-1060.
Read now
Deborah McK Ciombor, Ana Jaklenec, Alex Z. Liu, Christopher Thanos, Nausheen Rahman, Paula Weston, Roy Aaron & Edith Mathiowitz. (2006) Encapsulation of BSA using a modified W/O/O emulsion solvent removal method. Journal of Microencapsulation 23:2, pages 183-194.
Read now
Maite Estevan, Carlos Gamazo, Gustavo González-Gaitano & Juan M. Irache. (2006) Optimization of the entrapment of bacterial cell envelope extracts into microparticles for vaccine delivery. Journal of Microencapsulation 23:2, pages 169-181.
Read now
Jianbiao Ma, Haihui Cao, Yanhong Li & Youxin Li. (2002) Synthesis and characterization of poly(DL-lactide)-grafted gelatins as bioabsorbable amphiphilic polymers . Journal of Biomaterials Science, Polymer Edition 13:1, pages 67-80.
Read now
Rajeev S. Raghuvanshi, Om Singh, Amulya K. Panda. (2001) Formulation and Characterization of Immunoreactive Tetanus Toxoid Biodegradable Polymer Particles. Drug Delivery 8:2, pages 99-106.
Read now

Articles from other publishers (48)

Elizabeth G. Graham-Gurysh, Brandon W. Carpenter, Wolfgang A. Beck, Devika M. Varma, Benjamin G. Vincent, Eric M. Bachelder & Kristy M. Ainslie. 2022. Systemic Drug Delivery Strategies. Systemic Drug Delivery Strategies 359 408 .
Matilde Durán-Lobato, Ana María López-Estévez, Ana Sara Cordeiro, Tamara G. Dacoba, José Crecente-Campo, Dolores Torres & María José Alonso. (2021) Nanotechnologies for the delivery of biologicals: Historical perspective and current landscape. Advanced Drug Delivery Reviews 176, pages 113899.
Crossref
Christopher J. Genito, Cole J. Batty, Eric M. Bachelder & Kristy M. Ainslie. (2021) Considerations for Size, Surface Charge, Polymer Degradation, Co‐Delivery, and Manufacturability in the Development of Polymeric Particle Vaccines for Infectious Diseases. Advanced NanoBiomed Research 1:3, pages 2000041.
Crossref
Eric M. Bachelder, Erica N. Pino & Kristy M. Ainslie. (2016) Acetalated Dextran: A Tunable and Acid-Labile Biopolymer with Facile Synthesis and a Range of Applications. Chemical Reviews 117:3, pages 1915-1926.
Crossref
Min Jung Kim, Seok Chan Park & Seong-O Choi. (2017) Dual-nozzle spray deposition process for improving the stability of proteins in polymer microneedles. RSC Advances 7:87, pages 55350-55359.
Crossref
Stephany Y. Tzeng, Rohiverth Guarecuco, Kevin J. McHugh, Sviatlana Rose, Evan M. Rosenberg, Yingying Zeng, Robert Langer & Ana Jaklenec. (2016) Thermostabilization of inactivated polio vaccine in PLGA-based microspheres for pulsatile release. Journal of Controlled Release 233, pages 101-113.
Crossref
Grace A. Ledet, Richard A. Graves, Levon A. Bostanian & Tarun K. Mandal. 2015. Lyophilized Biologics and Vaccines. Lyophilized Biologics and Vaccines 273 297 .
Jiming Xuan, Yaling Lin, Jingbin Huang, Fei Yuan, Xiaoqing Li, Ying Lu, He Zhang, Junjie Liu, Zhiguo Sun, Hao Zou, Yan Chen, Jing Gao & Yanqiang Zhong. (2013) Exenatide-loaded PLGA microspheres with improved glycemic control: In vitro bioactivity and in vivo pharmacokinetic profiles after subcutaneous administration to SD rats. Peptides 46, pages 172-179.
Crossref
Christian Wischke, Cornelius Schneider, Axel T. Neffe & Andreas Lendlein. (2013) Polyalkylcyanoacrylates as in situ formed diffusion barriers in multimaterial drug carriers. Journal of Controlled Release 169:3, pages 321-328.
Crossref
Kashappa-Goud H. Desai, Samer Kadous & Steven P. Schwendeman. (2013) Gamma Irradiation of Active Self-Healing PLGA Microspheres for Efficient Aqueous Encapsulation of Vaccine Antigens. Pharmaceutical Research 30:7, pages 1768-1778.
Crossref
Kashappa-Goud H. Desai & Steven P. Schwendeman. (2013) Active self-healing encapsulation of vaccine antigens in PLGA microspheres. Journal of Controlled Release 165:1, pages 62-74.
Crossref
My-Kien Tran, Amin Swed & Frank Boury. (2012) Preparation of polymeric particles in CO2 medium using non-toxic solvents: Formulation and comparisons with a phase separation method. European Journal of Pharmaceutics and Biopharmaceutics 82:3, pages 498-507.
Crossref
C. Wischke & S. P. Schwendeman. 2012. Fundamentals and Applications of Controlled Release Drug Delivery. Fundamentals and Applications of Controlled Release Drug Delivery 171 228 .
Vesna Milacic, Brittany Agius Bailey, Derek O’Hagan & Steven P. Schwendeman. 2012. Long Acting Injections and Implants. Long Acting Injections and Implants 429 458 .
Tiantian Ren, Weien Yuan, Hao Zhao & Tuo Jin. (2011) Sustained-release polylactide-co-glycolide microspheres loaded with pre-formulated protein polysaccharide nanoparticles. Micro & Nano Letters 6:2, pages 70-74.
Crossref
Weien Yuan, Yulong Zhang, Fei Wu, Hui Li, Yunpeng Cai, Yuankuei Zhang, Mingjia Han & Tuo Jin. (2010) Preparation of protein-loaded sustained-release microspheres via ‘solid-in-oil-in-hydrophilic oil-in-ethanol (S/O/hO/E)’ emulsification. Colloids and Surfaces B: Biointerfaces 79:2, pages 326-333.
Crossref
Caroline Pérez, Ingrid J Castellanos, Henry R Costantino, Wasfi Al-Azzam & Kai Griebenow. (2002) Recent trends in stabilizing protein structure upon encapsulation and release from bioerodible polymers. Journal of Pharmacy and Pharmacology 54:3, pages 301-313.
Crossref
Ingrid J Castellanos, Karen G Carrasquillo, Jesiebel De Jésus López, Mariali Alvarez & Kai Griebenow. (2001) Encapsulation of bovine serum albumin in poly(lactide-co-glycolide) microspheres by the solid-in-oil-in-water technique. Journal of Pharmacy and Pharmacology 53:2, pages 167-178.
Crossref
Karen G Carrasquillo, Juan Carlos Aponte Carro, Adriana Alejandro, Diana Diaz Toro & Kai Griebenow. (2001) Reduction of structural perturbations in bovine serum albumin by non-aqueous microencapsulation. Journal of Pharmacy and Pharmacology 53:1, pages 115-120.
Crossref
S. Vicente, C. Prego, N. Csaba & M.J. Alonso. (2010) From single-dose vaccine delivery systems to nanovaccines. Journal of Drug Delivery Science and Technology 20:4, pages 267-276.
Crossref
Sheng Qi, Delphine Marchaud & Duncan Q.M. Craig. (2010) An investigation into the mechanism of dissolution rate enhancement of poorly water-soluble drugs from spray chilled gelucire 50/13 microspheres. Journal of Pharmaceutical Sciences 99:1, pages 262-274.
Crossref
Jocimara Namur, Célia Takata, Pedro De Araujo & Maria Bueno-da-Costa. (2009) Hoffmeister Series Ions Protect Diphtheria Toxoid from Structural Damages at Solvent/Water Interface. Materials 2:3, pages 765-775.
Crossref
Fei Wu & Tuo Jin. (2008) Polymer-Based Sustained-Release Dosage Forms for Protein Drugs, Challenges, and Recent Advances. AAPS PharmSciTech 9:4, pages 1218-1229.
Crossref
Martin Körber & Roland Bodmeier. (2008) Development of an in situ forming PLGA drug delivery system. European Journal of Pharmaceutical Sciences 35:4, pages 283-292.
Crossref
Wenlei Jiang & Steven P. Schwendeman. (2008) Stabilization of Tetanus Toxoid Encapsulated in PLGA Microspheres. Molecular Pharmaceutics 5:5, pages 808-817.
Crossref
A. Nordgreen, K. Hamre & C. Langdon. (2007) Development of lipid microbeads for delivery of lipid and water-soluble materials to Artemia. Aquaculture 273:4, pages 614-623.
Crossref
Akihiro Matsumoto, Yasuhisa Matsukawa, Yuji Horikiri & Takehiko Suzuki. (2006) Rupture and drug release characteristics of multi-reservoir type microspheres with poly(dl-lactide-co-glycolide) and poly(dl-lactide). International Journal of Pharmaceutics 327:1-2, pages 110-116.
Crossref
H. L. Jiang & K. J. Zhu. (2006) Comparison of poly(aspartic acid) hydrogel and poly(aspartic acid)/gelatin complex for entrapment and pH-sensitive release of protein drugs. Journal of Applied Polymer Science 99:5, pages 2320-2329.
Crossref
Y. Li, H.L. Jiang, K.J. Zhu, J.H. Liu & Y.L. Hao. (2005) Preparation, characterization and nasal delivery of α-cobrotoxin-loaded poly(lactide-co-glycolide)/polyanhydride microspheres. Journal of Controlled Release 108:1, pages 10-20.
Crossref
Xiaofei Yuan, Yuichi Yamasaki, Atsushi Harada & Kazunori Kataoka. (2005) Characterization of stable lysozyme-entrapped polyion complex (PIC) micelles with crosslinked core by glutaraldehyde. Polymer 46:18, pages 7749-7758.
Crossref
Xian-Zheng Zhang & Chih-Chang Chu. (2005) Temperature-Sensitive Poly(N-Isopropylacrylamide)/Poly(Ethylene Glycol) Diacrylate Hydrogel Microspheres. American Journal of Drug Delivery 3:1, pages 55-65.
Crossref
W.Thomas Leach, Dale T. Simpson, Tibisay N. Val, Efemona C. Anuta, Zhongshui Yu, Robert O. WilliamsIIIIII & Keith P. Johnston. (2005) Uniform Encapsulation of Stable Protein Nanoparticles Produced by Spray Freezing for the Reduction of Burst Release. Journal of Pharmaceutical Sciences 94:1, pages 56-69.
Crossref
Xian-Zheng Zhang & Chih-Chang Chu. (2004) A responsive poly(N-isopropylacrylamide)/poly(ethylene glycol) diacrylate hydrogel microsphere. Colloid and Polymer Science 282:12, pages 1415-1420.
Crossref
Jianjun Wang, Kay Ming Chua & Chi-Hwa Wang. (2004) Stabilization and encapsulation of human immunoglobulin G into biodegradable microspheres. Journal of Colloid and Interface Science 271:1, pages 92-101.
Crossref
Kinam Park & Yoon Yeo. 2003. Tissue Engineering And Novel Delivery Systems. Tissue Engineering And Novel Delivery Systems.
Alejandro Sánchez, Marı́a Tobı́o, Libia González, Angels Fabra & Marı́a J Alonso. (2003) Biodegradable micro- and nanoparticles as long-term delivery vehicles for interferon-alpha. European Journal of Pharmaceutical Sciences 18:3-4, pages 221-229.
Crossref
J. H. LIN, C. N. WENG, C. W. LIAO, K. S. YEH & M. J. PAN. (2003) Protective Effects of Oral Microencapsulated Mycoplasma hyopneumoniae Vaccine Prepared by Co-Spray Drying Method.. Journal of Veterinary Medical Science 65:1, pages 69-74.
Crossref
Rajeev S Raghuvanshi, Yogesh K Katare, Komal Lalwani, Mushir M Ali, Om Singh & Amulya K Panda. (2002) Improved immune response from biodegradable polymer particles entrapping tetanus toxoid by use of different immunization protocol and adjuvants. International Journal of Pharmaceutics 245:1-2, pages 109-121.
Crossref
Marja Savolainen, Cynthia Khoo, Håkan Glad, Carina Dahlqvist & Anne Mari Juppo. (2002) Evaluation of controlled-release polar lipid microparticles. International Journal of Pharmaceutics 244:1-2, pages 151-161.
Crossref
J. H. Lin, M. J. Pan, C. W. Liao & C. N. Weng. (2002) In vivo and in vitro comparisons of spray-drying and solvent-evaporation preparation of microencapsulated Mycoplasma hyopneumoniae for use as an orally administered vaccine for pigs. American Journal of Veterinary Research 63:8, pages 1118-1123.
Crossref
Tobias Jung, Regina Koneberg, Klaus-D. Hungerer & Thomas Kissel. (2002) Tetanus toxoid microspheres consisting of biodegradable poly(lactide-co-glycolide)- and ABA-triblock-copolymers: immune response in mice. International Journal of Pharmaceutics 234:1-2, pages 75-90.
Crossref
Allison Radwick & Diane Burgess. 2002. Protein-Based Films and Coatings. Protein-Based Films and Coatings.
Karen G Carrasquillo, Ann M Stanley, Juan C Aponte-Carro, Patricia De Jésus, Henry R Costantino, Carlos J Bosques & Kai Griebenow. (2001) Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly(lactide-co-glycolide) microspheres results in release of native protein. Journal of Controlled Release 76:3, pages 199-208.
Crossref
Shari Lofthouse, Shunji Nagahara, Bradley Sedgmen, Garry Barcham, Malcolm Brandon & Akihiko Sano. (2001) The application of biodegradable collagen minipellets as vaccine delivery vehicles in mice and sheep. Vaccine 19:30, pages 4318-4327.
Crossref
C Perez, A Sanchez, D Putnam, D Ting, R Langer & M.J Alonso. (2001) Poly(lactic acid)-poly(ethylene glycol) nanoparticles as new carriers for the delivery of plasmid DNA. Journal of Controlled Release 75:1-2, pages 211-224.
Crossref
Anna B. Sasiak, Barbara Bolgiano, Dennis T. Crane, David J. Hockley, Michael J. Corbel & Dorothea Sesardic. (2000) Comparison of in vitro and in vivo methods to study stability of PLGA microencapsulated tetanus toxoid vaccines. Vaccine 19:7-8, pages 694-705.
Crossref
Gaozhong Zhu, Susan R. Mallery & Steven P. Schwendeman. (2000) Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide). Nature Biotechnology 18:1, pages 52-57.
Crossref
M. Tobı́o, S.P. Schwendeman, Y. Guo, J. McIver, R. Langer & M.J. Alonso. (1999) Improved immunogenicity of a core-coated tetanus toxoid delivery system. Vaccine 18:7-8, pages 618-622.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.