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Original Article

Hyperthermia combined with chemotherapy and irradiation for patients with carcinoma of the oesophagus—A prospective randomized trial

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Pages 289-295 | Received 01 Jul 1991, Accepted 14 Oct 1991, Published online: 09 Jul 2009

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Nikola Cihoric, Alexandros Tsikkinis, Gerard van Rhoon, Hans Crezee, Daniel M. Aebersold, Stephan Bodis, Marcus Beck, Jacek Nadobny, Volker Budach, Peter Wust & Pirus Ghadjar. (2015) Hyperthermia-related clinical trials on cancer treatment within the ClinicalTrials.gov registry. International Journal of Hyperthermia 31:6, pages 609-614.
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Deng-Hai Mi, Zheng Li, Ke-Hu Yang, Nong Cao, Anne Lethaby, Jin-Hui Tian, Nancy Santesso, Bin Ma, Yao-Long Chen & Ya-Li Liu. (2013) Surgery combined with intraoperative hyperthermic intraperitoneal chemotherapy (IHIC) for gastric cancer: A systematic review and meta-analysis of randomised controlled trials. International Journal of Hyperthermia 29:2, pages 156-167.
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Sarah H. Beachy & Elizabeth A. Repasky. (2011) Toward establishment of temperature thresholds for immunological impact of heat exposure in humans. International Journal of Hyperthermia 27:4, pages 344-352.
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Chen-Ting Lee, Thomas Mace & Elizabeth A. Repasky. (2010) Hypoxia-driven immunosuppression: A new reason to use thermal therapy in the treatment of cancer?. International Journal of Hyperthermia 26:3, pages 232-246.
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Olav Dahl. (1999) Status of Clinical Hyperthermia. Acta Oncologica 38:7, pages 863-873.
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C. QI, D.-J. LI. (1999) Thermometric analysis of intra-cavitary hyperthermia for esophageal cancer. International Journal of Hyperthermia 15:5, pages 399-407.
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K. Kitamura, H. Kuwano, K. Araki, A. Egashira, H. Kawaguchi, H. Saeki, M. Morita, S. Ohno & K. Sugimachi. (1998) Clinicopathologic Features of Patients with Oesophageal Cancer Obtaining a Histological Complete Response for Preoperative Hyperthermo-Chemo-Radiotherapy. International Journal of Hyperthermia 14:3, pages 233-243.
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K. Sugimach, H. Kuwano, H. Ide, T. Toge, M. Saku & Y. Oshiumi. (1994) Chemotherapy combined with or without hyperthermia for patients with oesophageal carcinoma: a prospective randomized trial. International Journal of Hyperthermia 10:4, pages 485-493.
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Lucian Mocan, Ofelia Mosteanu, Teodora Pop, Lucia Agoston-Coldea, Cornel Iancu, Teodora Mocan & Furcea Luminita. 2017. Esophageal Abnormalities. Esophageal Abnormalities.
Y. Hu, Z. Li, D.-H. Mi, N. Cao, S.-W. Zu, Z.-Z. Wen, X.-L. Yu & Y. Qu. (2017) Chemoradiation combined with regional hyperthermia for advanced oesophageal cancer: a systematic review and meta-analysis. Journal of Clinical Pharmacy and Therapeutics 42:2, pages 155-164.
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Jen-Tsan Chi, Donald E. Thrall, Chen Jiang, Stacey Snyder, Diane Fels, Chelsea Landon, Linda McCall, Lan Lan, Marlene Hauck, James R. MacFall, Benjamin L. Viglianti & Mark W. Dewhirst. (2011) Comparison of Genomics and Functional Imaging from Canine Sarcomas Treated with Thermoradiotherapy Predicts Therapeutic Response and Identifies Combination Therapeutics. Clinical Cancer Research 17:8, pages 2549-2560.
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Adrienne J. Peer, Melissa J. Grimm, Evan R. Zynda & Elizabeth A. Repasky. (2009) Diverse immune mechanisms may contribute to the survival benefit seen in cancer patients receiving hyperthermia. Immunologic Research 46:1-3, pages 137-154.
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Rebecca KS Wong & Richard Malthaner. (2010) Combined chemotherapy and radiotherapy (without surgery) compared with radiotherapy alone in localized carcinoma of the esophagus. Cochrane Database of Systematic Reviews.
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Riadh Habash. 2007. Bioeffects and Therapeutic Applications of Electromagnetic Energy. Bioeffects and Therapeutic Applications of Electromagnetic Energy 221 263 .
Christopher A. Garces, Priscilla F. McAuliffe, Steven N. Hochwald & William G. Cance. (2006) Neoadjuvant Therapy in the Treatment of Solid Tumors. Current Problems in Surgery 43:7, pages 462-551.
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Rebecca KS Wong & Richard Malthaner. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
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E. Dieter Hager. 2006. Hyperthermia in Cancer Treatment: A Primer. Hyperthermia in Cancer Treatment: A Primer 167 182 .
Xiaoyong Yang, Jianjun Du & Youjun Liu. (2005) Advances in Hyperthermia Technology. Advances in Hyperthermia Technology.
Wolfgang Hiddemann, Heinz Huber & Claus R. BartramM. Schlemmer, L. H. Lindner & R. D. Issels. 2004. Die Onkologie. Die Onkologie 563 577 .
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Ikuo Takahashi, Yasunori Emi, Shota Hasuda, Yoshihiro Kakeji, Yoshihiko Maehara & Keizo Sugimachi. (2002) Clinical application of hyperthermia combined with anticancer drugs for the treatment of solid tumors. Surgery 131:1, pages S78-S84.
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Tadahiro Nozoe, Hiroshi Saeki, Shuhei Ito, Takefumi Ohga & Kaoru Kitamura. (2002) Preoperative hyperthermochemoradiotherapy for esophageal carcinoma. Surgery 131:1, pages S35-S38.
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Hong Jin Kim & Manjit S. Bains. (2002) Randomized Clinical Trials in Esophageal Cancer. Surgical Oncology Clinics of North America 11:1, pages 89-109.
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N Fuwa, Y Nomoto, K Shouji, T Kodaira, M Kamata & Y Ito. (2001) Therapeutic effects of simultaneous intraluminal irradiation and intraluminal hyperthermia on oesophageal carcinoma. The British Journal of Radiology 74:884, pages 709-714.
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Masaru Morita, Hiroyuki Kuwano, Kohshi Araki, Akinori Egashira, Hidetoshi Kawaguchi, Hiroshi Saeki, Kaoru Kitamura, Shinji Ohno & Keizo Sugimachi. (2001) Prognostic significance of lymphocyte infiltration following preoperative chemoradiotherapy and hyperthermia for esophageal cancer. International Journal of Radiation Oncology*Biology*Physics 49:5, pages 1259-1266.
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Hiroshi Saeki, Hidetoshi Kawaguchi, Kaoru Kitamura, Shinji Ohno & Keizo Sugimachi. (1998) Recent advances in preoperative hyperthermochemoradiotherapy for patients with esophageal cancer. Journal of Surgical Oncology 69:4, pages 224-229.
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Beate Rau, Peter Wust, Peter Hohenberger, Juergen Löffel, Michael Hünerbein, Cathlen Below, Johanna Gellermann, Andrea Speidel, Thomas Vogl, Hanno Riess, Roland Felix & Peter M. Schlag. (1998) Preoperative Hyperthermia Combined with Radiochemotherapy in Locally Advanced Rectal Cancer. Annals of Surgery 227:3, pages 380-389.
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Takashi Sakamoto, Hiroshi Katoh, Tetsuro Shimizu, Iwao Yamashita, Shigeru Takemori, Kenji Tazawa & Masao Fujimaki. (1997) Clinical Results of Treatment of Advanced Esophageal Carcinoma With Hyperthermia in Combination With Chemoradiotherapy. Chest 112:6, pages 1487-1493.
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M. Heinrich Seegenschmiedt, Peter Fessenden & Clare C. VernonZ. Petrovich, P. Debicki, M. A. Astrahan & L. Baert. 1996. Thermoradiotherapy and Thermochemotherapy. Thermoradiotherapy and Thermochemotherapy 263 274 .
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Kaoru Kitamura, Hiroyuki Kuwano, Masayuki Watanabe, Tadahiro Nozoe, Mitsuhiro Yasuda, Kohei Sumiyoshi, Motonori Saku & Keizo Sugimachi. (2006) Prospective randomized study of hyperthermia combined with chemoradiotherapy for esophageal carcinoma. Journal of Surgical Oncology 60:1, pages 55-58.
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Tadahiro Nozoe, Hiroyuki Kuwano, Masayuki Watanabe, Mitsuhiro Yasuda, Noriaki Sadanaga, Koushi Mimori & Keizo Sugimachi. (1995) The long-term results of pre-operative hyperthermo-chemoradiotherapy for oesophageal carcinoma—a comparison with preoperative radiation therapy alone. European Journal of Surgical Oncology (EJSO) 21:4, pages 374-378.
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Tetsuro Nishihira, Tatsuya Nakano & Shozo Mori. (1994) Adjuvant therapies for cancer of the thoracic esophagus. World Journal of Surgery 18:3, pages 388-398.
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Keizo Sugimachi, Masaki Mori, Hideo Baba, Masayuki Watanabe, Noriaki Sadanaga, Masahiko Ikebe & Hiroyuki Kuwano. 1993. Recent Advances in Management of Digestive Cancers. Recent Advances in Management of Digestive Cancers 160 165 .

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