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Research Article

Dexmedetomidine renders a brain protection on hippocampal formation through inhibition of nNOS-NO signalling in endotoxin-induced shock rats

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Pages 1003-1008 | Received 08 Sep 2013, Accepted 26 Jan 2014, Published online: 30 Apr 2014

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Ling Wu, Yalin Xi & Qinglong Kong. (2020) Dexmedetomidine protects PC12 cells from oxidative damage through regulation of miR-199a/HIF-1α. Artificial Cells, Nanomedicine, and Biotechnology 48:1, pages 506-514.
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Liangyuan Suo & Mingyu Wang. (2021) Dexmedetomidine facilitates the expression of nNOS in the hippocampus to alleviate surgery‑induced neuroinflammation and cognitive dysfunction in aged rats. Experimental and Therapeutic Medicine 22:3.
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Man‑He Zhang, Xiu‑Min Zhou, Jian‑Zhong Cui, Kai‑Jie Wang, Yan Feng & Hong‑Ao Zhang. (2018) Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression. Molecular Medicine Reports.
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Jing Dong, Xin Guo, Shuhua Yang & Lin Li. (2017) The effects of dexmedetomidine preconditioning on aged rat heart of ischaemia reperfusion injury. Research in Veterinary Science 114, pages 489-492.
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Ning Zhang, Quan-ping Su, Wei-xia Zhang, Nian-jun Shi, Hao Zhang, Ling-ping Wang, Zhong-kai Liu & Ke-zhong Li. (2017) Neuroprotection of dexmedetomidine against propofol-induced neuroapoptosis partly mediated by PI3K/Akt pathway in hippocampal neurons of fetal ratPI3K/Akt 信号通路部分参与了右美托咪定对异丙酚诱导的胎鼠海马神经元凋亡的保护作用. Journal of Zhejiang University-SCIENCE B 18:9, pages 789-796.
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Azeem Alam, Ka Chun Suen, Zac Hana, Robert D. Sanders, Mervyn Maze & Daqing Ma. (2017) Neuroprotection and neurotoxicity in the developing brain: an update on the effects of dexmedetomidine and xenon. Neurotoxicology and Teratology 60, pages 102-116.
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Shan-Shan Zheng, Xin-Ye Qian, Si-Yuan Li & Xuan Zhao. (2016) Interventional therapy of diabetes mellitus type 2 complicated with acute cerebral hemorrhage by using dexmedetomidine. Journal of Acute Disease 5:5, pages 419-422.
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Marco Sifringer, Clarissa von Haefen, Maria Krain, Nadine Paeschke, Ivo Bendix, Christoph Bührer, Claudia D. Spies & Stefanie Endesfelder. (2015) Neuroprotective Effect of Dexmedetomidine on Hyperoxia-Induced Toxicity in the Neonatal Rat Brain. Oxidative Medicine and Cellular Longevity 2015, pages 1-10.
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