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Short Communication

Tacrolimus-Loaded PLGA Implants: In Vivo Release and Ocular Toxicity

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Pages 99-102 | Received 20 Nov 2012, Accepted 21 Jun 2013, Published online: 10 Dec 2013

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Qianni Wu, Dong Liu, Xulin Zhang, Dongni Wang, Meimei DongYe, Wan Chen, Duoru Lin, Fangming Zhu, Weirong Chen & Haotian Lin. (2019) Development and effects of tacrolimus-loaded nanoparticles on the inhibition of corneal allograft rejection. Drug Delivery 26:1, pages 290-299.
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Paulina García-Estrada, Miguel A. García-Bon, Edgar J. López-Naranjo, Dulce N. Basaldúa-Pérez, Arturo Santos & Jose Navarro-Partida. (2021) Polymeric Implants for the Treatment of Intraocular Eye Diseases: Trends in Biodegradable and Non-Biodegradable Materials. Pharmaceutics 13:5, pages 701.
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Mayara Rodrigues Brandão Paiva, Gracielle Ferreira Andrade, Lays Fernanda Nunes DouradoBrenda Fernanda Moreira CastroSilvia Ligório Fialho, Edésia Martins Barros Sousa & Armando Silva-Cunha. (2020) Surface functionalized mesoporous silica nanoparticles for intravitreal application of tacrolimus. Journal of Biomaterials Applications 35:8, pages 1019-1033.
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Mayara Rodrigues Brandão De Paiva, Daniel Vítor Vasconcelos-Santos, Lorena Carla Vieira, Sílvia Ligório Fialho & Armando Silva-Cunha. (2021) Sirolimus-Loaded Intravitreal Implant for Effective Treatment of Experimental Uveitis. AAPS PharmSciTech 22:1.
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Dong‐In Kim, Hyoryong Lee, Su‐Hyun Kwon, Young Je Sung, Won Kyung Song & Sukho Park. (2020) Bilayer Hydrogel Sheet‐Type Intraocular Microrobot for Drug Delivery and Magnetic Nanoparticles Retrieval. Advanced Healthcare Materials 9:13, pages 2000118.
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Brenda Fernanda Moreira Castro, Lorena Carla Vieira, Daniel Vitor Vasconcelos-Santos, Sarah Pereira de Freitas Cenachi, Oliver Araújo Lacerda Cotta, Maria Carolina Andrade Guerra, Mayara Rodrigues Brandão Paiva, Luciana Maria Silva, Armando Silva-Cunha & Sílvia Ligório Fialho. (2020) Intravitreal thalidomide ameliorates inflammation in a model of experimental uveitis induced by BCG. International Immunopharmacology 81, pages 106129.
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Mayara Rodrigues Brandão De Paiva, Nayara Almeida Lage, Maria Carolina Andrade Guerra, Marcos Paulo Gomes Mol, Marcela Coelho Silva Ribeiro, Gustavo De Oliveira Fulgêncio, Dawidson A. Gomes, Isabela Da Costa César, Sílvia Ligório Fialho & Armando Silva-Cunha. (2018) Toxicity and in vivo release profile of sirolimus from implants into the vitreous of rabbits’ eyes. Documenta Ophthalmologica 138:1, pages 3-19.
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Julie Schallhorn. 2019. Posterior Uveitis. Posterior Uveitis 209 225 .
Kritika Nayak & Manju Misra. (2018) A review on recent drug delivery systems for posterior segment of eye. Biomedicine & Pharmacotherapy 107, pages 1564-1582.
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Divya Dheer, Jyoti, Prem N. Gupta & Ravi Shankar. (2018) Tacrolimus: An updated review on delivering strategies for multifarious diseases. European Journal of Pharmaceutical Sciences 114, pages 217-227.
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Leandro Gonzaga De Oliveira, Marina Barcelos De Miranda, Sandra Aparecida Lima De Moura & Gisele Rodrigues Da Silva. (2018) Tacrolimus delivered from polymeric implants suppressed inflammation and angiogenesis in vivo without inducing nephrotoxicity, hepatotoxicity, and myelosuppression. Journal of Drug Delivery Science and Technology 43, pages 487-495.
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Gisele R. Silva, Ana Paula R. Almeida, Gabriella M. Fernandes-Cunha, Brenda F.M. Castro, Lorena C. Vieira, Gustavo O. Fulgêncio, Armando Silva-Cunha & Sílvia L. Fialho. (2016) Safety and in vivo release of fluconazole-loaded implants in rabbits' eyes. Journal of Drug Delivery Science and Technology 35, pages 323-326.
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Naba Elsaid, Timothy L. Jackson, Zeeneh Elsaid, Aljawharah Alqathama & Satyanarayana Somavarapu. (2016) PLGA Microparticles Entrapping Chitosan-Based Nanoparticles for the Ocular Delivery of Ranibizumab. Molecular Pharmaceutics 13:9, pages 2923-2940.
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Morgan V. Fedorchak, Ian P. Conner, Carlos A. Medina, Jeremy B. Wingard, Joel S. Schuman & Steven R. Little. (2014) 28-day intraocular pressure reduction with a single dose of brimonidine tartrate-loaded microspheres. Experimental Eye Research 125, pages 210-216.
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