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Current Eye Research Volume 39, 2014 - Issue 1
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Research Article

The Application of Autologous Serum Eye Drops in Severe Dry Eye Patients; Subjective and Objective Parameters Before and After Treatment

Katerina JirsovaLaboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and First Faculty of Medicine Charles University in PragueCzech RepublicCorrespondence[email protected]
,
Kristyna BrejchovaLaboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and First Faculty of Medicine Charles University in PragueCzech Republic
,
Ivana KrabcovaLaboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and First Faculty of Medicine Charles University in PragueCzech Republic
,
Martin FilipecEuropean Eye Clinic Lexum PragueCzech Republic
,
Aref Al FakihLaboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and First Faculty of Medicine Charles University in PragueCzech Republic
,
Michalis PalosDepartment of Ophthalmology, General Teaching Hospital and Charles University in Prague, First Faculty of Medicine PragueCzech Republic
&
Viera VeselaLaboratory of the Biology and Pathology of the Eye, Institute of Inherited Metabolic Disorders, General Teaching Hospital and First Faculty of Medicine Charles University in PragueCzech Republic
 show all
Pages 21-30 | Received 11 Feb 2013, Accepted 08 Jul 2013, Published online: 27 Sep 2013

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Michael J. Doughty. (2017) A Grid-Based Nucleus Counting Method for Estimates of the Density of Superficial Conjunctival Cells from Impression Cytology Samples Taken from Normal Healthy Human Eyes. Current Eye Research 42:9, pages 1228-1234.
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Nariman Nassiri, Yasaira Rodriguez Torres, Zachary Meyer, Michael A. Beyer, Gautham Vellaichamy, Amar S. Dhaliwal, Neil Chungfat & Frank S. Hwang. (2017) Current and emerging therapy of dry eye disease. Part A: pharmacological modalities. Expert Review of Ophthalmology 12:4, pages 269-297.
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Gabriela Mahelkova, Katerina Jirsova, Petra Seidler stangova, Michalis Palos, Viera Vesela, Ivan Fales, Nada Jiraskova & Dagmar Dotrelova. (2017) Using corneal confocal microscopy to track changes in the corneal layers of dry eye patients after autologous serum treatment. Clinical and Experimental Optometry 100:3, pages 243-249.
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Articles from other publishers (27)

Şule Nur ACAR DUYAN, Banu BOZKURT, Ali UNLU, Sema YİLMAZ & Yalçın KARAKÜÇÜK. (2023) Serum Inflammatory Cytokines and Growth Factors in Patients with Sjögren’s Syndrome and Diabetes MellitusSjögren Sendromlu ve Diabetik Hastalarda Serum Büyüme Faktörleri ve İnflamatuar Sitokin Düzeyleri. Genel Tıp Dergisi 33:4, pages 360-366.
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Özgür Eroğul, Aydın Balcı, Hamidu Hamisi Gobeka, Neriman Efe, Müberra Akdoğan, Ayşe Yeşim Oral, Mustafa Doğan, Çiğdem Özdemir, Murat Kaşıkçı & Sinan Saraçlı. (2023) Conjunctival Impression Cytology and Tear Film Changes in Sarcoidosis: A Subjective and Objective Diagnosis Study. Turkish Journal of Ophthalmology 53:4, pages 200-205.
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Dian Zhuang, Stuti L. Misra, Odunayo O. Mugisho, Ilva D. Rupenthal & Jennifer P. Craig. (2023) NLRP3 Inflammasome as a Potential Therapeutic Target in Dry Eye Disease. International Journal of Molecular Sciences 24:13, pages 10866.
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Dominika Wróbel-Dudzińska, Agata Przekora, Paulina Kazimierczak, Agnieszka Ćwiklińska-Haszcz, Ewa Kosior-Jarecka & Tomasz Żarnowski. (2023) The Comparison between the Composition of 100% Autologous Serum and 100% Platelet-Rich Plasma Eye Drops and Their Impact on the Treatment Effectiveness of Dry Eye Disease in Primary Sjogren Syndrome. Journal of Clinical Medicine 12:9, pages 3126.
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Neha Kumari, Rakhi Kusumesh, Rekha Kumari, Bibhuti Prassan Sinha & Vivek Singh. (2023) Comparative evaluation of effectiveness of twenty versus fifty percent autologous serum eye drops in treatment of dry eye. Indian Journal of Ophthalmology 71:4, pages 1603-1607.
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Maria Luisa Pérez, Saúl Barreales, Noelia Sabater-Cruz, Eva Maria Martinez-Conesa, Anna Vilarrodona & Ricardo P. Casaroli-Marano. (2021) Amniotic membrane extract eye drops: a new approach to severe ocular surface pathologies. Cell and Tissue Banking 23:3, pages 473-481.
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Katerina Jirsova, K. Levova, M. Kalousova, I. Fales, V. Frankova, V. Vesela, T. Zima, T. P. Utheim & J. Bednar. (2022) Time and Temperature Stability of TGF-β1, EGF and IGF-1 in 20% and 100% Human Serum. Folia Biologica 68:2, pages 45-49.
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Alice T. Yu, Graham A. Lee, Stephen Vincent & Peter Shah. (2020) Patient perceptions of autologous serum eye drops for severe dry eye disease. Clinical & Experimental Ophthalmology 48:8, pages 1109-1111.
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Katerina Jirsova, Petra Seidler Stangova, Michalis Palos, Gabriela Mahelkova, Sarka Kalasova, Ivana Rybickova, Tor Paaske Utheim & Viera Vesela. (2020) Aberrant HLA-DR expression in the conjunctival epithelium after autologous serum treatment in patients with graft-versus-host disease or Sjögren’s syndrome. PLOS ONE 15:4, pages e0231473.
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Federico Bernabei, Matilde Roda, Marina Buzzi, Marco Pellegrini, Giuseppe Giannaccare & Piera Versura. (2019) Blood-Based Treatments for Severe Dry Eye Disease: The Need of a Consensus. Journal of Clinical Medicine 8:9, pages 1478.
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Michael Marchand, Mona Harissi-Dagher, Marc Germain, Paul Thompson & Marie-Claude Robert. (2018) Serum drops for ocular surface disease: national survey of Canadian cornea specialists. Canadian Journal of Ophthalmology 53:3, pages 266-271.
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Suzanne Hagan. (2017) Biomarkers of ocular surface disease using impression cytology. Biomarkers in Medicine 11:12, pages 1135-1147.
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Gabriela Dieckmann, Sunali Goyal & Pedram Hamrah. (2017) Neuropathic Corneal Pain. Ophthalmology 124:11, pages S34-S47.
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Lyndon Jones, Laura E. Downie, Donald Korb, Jose M. Benitez-del-Castillo, Reza Dana, Sophie X. Deng, Pham N. Dong, Gerd Geerling, Richard Yudi Hida, Yang Liu, Kyoung Yul Seo, Joseph Tauber, Tais H. Wakamatsu, Jianjiang Xu, James S. Wolffsohn & Jennifer P. Craig. (2017) TFOS DEWS II Management and Therapy Report. The Ocular Surface 15:3, pages 575-628.
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Ronald Mauricio Sanchez-AvilaJesus Merayo-LlovesAna Cristina RiestraEduardo AnituaFrancisco MuruzabalGorka OriveLuis Fernández-Vega. (2017) The Effect of Immunologically Safe Plasma Rich in Growth Factor Eye Drops in Patients with Sjögren Syndrome. Journal of Ocular Pharmacology and Therapeutics 33:5, pages 391-399.
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D. C. Marks & P. F. van der Meer. (2017) Serum eye drops: a survey of international production methods. Vox Sanguinis 112:4, pages 310-317.
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Ivana Rybickova, Viera Vesela, Ivan Fales, Pavlina Skalicka & Katerina Jirsova. (2016) Apoptosis of conjunctival epithelial cells before and after the application of autologous serum eye drops in severe dry eye disease. Biomedical Papers 160:2, pages 271-275.
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Pieter F. van der Meer, Jerard Seghatchian & Denese C. Marks. (2016) Quality standards, safety and efficacy of blood-derived serum eye drops: A review. Transfusion and Apheresis Science 54:1, pages 164-167.
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Jesús Merayo-Lloves, Ronald M. Sanchez-Avila, Ana C. Riestra, Eduardo Anitua, Leire Begoña, Gorka Orive & Luis Fernandez-Vega. (2016) Safety and Efficacy of Autologous Plasma Rich in Growth Factors Eye Drops for the Treatment of Evaporative Dry Eye. Ophthalmic Research 56:2, pages 68-73.
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Jesús Merayo-Lloves, Ronald M. Sanchez, Ana C. Riestra, Eduardo Anitua, Leire Begoña, Gorka Orive & Luis Fernandez-Vega. (2016) Autologous Plasma Rich in Growth Factors Eyedrops in Refractory Cases of Ocular Surface Disorders. Ophthalmic Research 55:2, pages 53-61.
Crossref
Phillip Mondy, Tania Brama, Jenny Fisher, Carley N. Gemelli, Karen Chee, Anastazia Keegan & Daniel Waller. (2015) Sustained benefits of autologous serum eye drops on self-reported ocular symptoms and vision-related quality of life in Australian patients with dry eye and corneal epithelial defects. Transfusion and Apheresis Science 53:3, pages 404-411.
Crossref
Ying Liu, Masatoshi Hirayama, Xin Cui, Samuel Connell, Tetsuya Kawakita & Kazuo Tsubota. (2015) Effectiveness of Autologous Serum Eye Drops Combined With Punctal Plugs for the Treatment of Sjögren Syndrome–Related Dry Eye. Cornea 34:10, pages 1214-1220.
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Michael J. Doughty. (2015) Assessment of Consistency in Assignment of Severe (Grade 3) Squamous Metaplasia to Human Bulbar Conjunctiva Impression Cytology Cell Samples. The Ocular Surface 13:4, pages 284-297.
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Denese C. Marks, Jenny Fisher, Phillip Mondy, Jerard Segatchian & Peta M. Dennington. (2015) Serum eye drop preparation in Australia: Current manufacturing practice. Transfusion and Apheresis Science 53:1, pages 92-94.
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Amir A. Azari & Christopher J. Rapuano. (2015) Autologous Serum Eye Drops for the Treatment of Ocular Surface Disease. Eye & Contact Lens: Science & Clinical Practice 41:3, pages 133-140.
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Maria Rosaria De Pascale, Michele Lanza, Linda Sommese & Claudio Napoli. (2015) Human Serum Eye Drops in Eye Alterations: An Insight and a Critical Analysis. Journal of Ophthalmology 2015, pages 1-14.
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Francesco Semeraro, Eliana Forbice, Osvaldo Braga, Alessandro Bova, Attilio Di Salvatore & Claudio Azzolini. (2014) Evaluation of the Efficacy of 50% Autologous Serum Eye Drops in Different Ocular Surface Pathologies. BioMed Research International 2014, pages 1-11.
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