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Current Eye Research Volume 40, 2015 - Issue 4

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Original Article

The Changes of 8-OHdG, hOGG1, APE1 and Pol β in Lenses of Patients with Age-Related Cataract

Biwei XuEye Institute, Affiliated Hospital of Nantong University, Nantong, China

Lihua KangEye Institute, Affiliated Hospital of Nantong University, Nantong, China

Guowei ZhangEye Institute, Affiliated Hospital of Nantong University, Nantong, China

Jian WuEye Institute, Affiliated Hospital of Nantong University, Nantong, China

Rongrong ZhuEye Institute, Affiliated Hospital of Nantong University, Nantong, China

Mei YangEye Institute, Affiliated Hospital of Nantong University, Nantong, China

Huaijin GuanEye Institute, Affiliated Hospital of Nantong University, Nantong, ChinaCorrespondence[email protected]

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Pages 378-385 | Received 23 Feb 2014, Accepted 01 May 2014, Published online: 09 Jun 2014

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https://doi.org/10.3109/02713683.2014.924148
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Mengmeng Chen, Chunmei Zhang, Nan Zhou, Xu Wang, Dongmei Su & Yanhua Qi. (2021) Metformin alleviates oxidative stress‐induced senescence of human lens epithelial cells via AMPK activation and autophagic flux restoration. Journal of Cellular and Molecular Medicine 25:17, pages 8376-8389.
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Yang Huang, Zi Ye, Yujing Yin, Tianju Ma, Qi Zhang, Kun Shang, Wenqian Chen & Zhaohui Li. (2021) Cataract formation in transgenic HO-1 G143H mutant mice: Involvement of oxidative stress and endoplasmic reticulum stress. Biochemical and Biophysical Research Communications 537, pages 43-49.
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Emine KILIÇ TOPRAK, İbrahim TOPRAK, Volkan YAYLALI, Yasin ÖZDEMİR, Burak OYMAK, Melek BOR KÜÇÜKATAY & Vural KÜÇÜKATAY. (2019) Systemic Oxidant and Genotoxic Background in Exudative Age-Related Macular DegenerationIncreased Systemic Oxidative Stress and DNA Damage in Patients with Exudative Age-Related Macular Degeneration. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi 10:3, pages 273-277.
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Lihua Kang, Xi Zou, Guowei Zhang, Jing Xiang, Yong Wang, Mei Yang, Xiang Chen, Jian Wu & And Huaijin Guan. (2019) A variant in a microRNA binding site in NEIL2 3′UTR confers susceptibility to age‐related cataracts. The FASEB Journal 33:9, pages 10469-10476.
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Alice Uwineza, Alexia A. Kalligeraki, Nobuyuki Hamada, Miguel Jarrin & Roy A. Quinlan. (2019) Cataractogenic load – A concept to study the contribution of ionizing radiation to accelerated aging in the eye lens. Mutation Research/Reviews in Mutation Research 779, pages 68-81.
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Moonisah Usman & Emanuela V. Volpi. (2018) DNA damage in obesity: Initiator, promoter and predictor of cancer. Mutation Research/Reviews in Mutation Research 778, pages 23-37.
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Ding Zhou, Yi Zhang, Daxi Xue & Ping Liu. (2018) Protective Effects of Quercetin on Selenium-Induced Cataracts via Modulation of Heat Shock Protein 70 Expression. International Journal of Pharmacology 14:7, pages 913-921.
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Xiao-Cui Liu, Xiao-Hui Guo, Bing Chen, Zhao-Hui Li & Xiao-Fei Liu. (2017) Association between the 8-oxoguanine DNA glycosylase gene Ser326Cys polymorphism and age-related cataract: a systematic review and meta-analysis. International Ophthalmology 38:4, pages 1451-1457.
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Xinyue Shen, Manhui Zhu, Lihua Kang, Yuanyuan Tu, Lele Li, Rutan Zhang, Bai Qin, Mei Yang & Huaijin Guan. (2018) Lanosterol Synthase Pathway Alleviates Lens Opacity in Age-Related Cortical Cataract. Journal of Ophthalmology 2018, pages 1-9.
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Caroline S. Cencer, Shravan K. Chintala, Tenira J. Townsend, Daniel P. Feldmann, Mirna A. Awrow, Nahrain A. Putris, Mason E. Geno, Maria G. Donovan & Frank J. Giblin. (2018) PARP-1/PAR Activity in Cultured Human Lens Epithelial Cells Exposed to Two Levels of UVB Light. Photochemistry and Photobiology 94:1, pages 126-138.
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Fenil Shah, Derek Logsdon, Richard A. Messmann, Jill C. Fehrenbacher, Melissa L. Fishel & Mark R. Kelley. (2017) Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic. npj Precision Oncology 1:1.
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Yong Wang, Junfang Zhang, Jian Wu & Huaijin Guan. (2017) Expression of DNA repair genes in lens cortex of age-related cortical cataract. Experimental and Molecular Pathology 102:2, pages 219-223.
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Ning-hua Cui, Chen Qiao, Xiao-ke Chang & Li Wei. (2017) Associations of PARP-1 variant rs1136410 with PARP activities, oxidative DNA damage, and the risk of age-related cataract in a Chinese Han population: A two-stage case-control analysis. Gene 600, pages 70-76.
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Hongxu Zhang, Jianguang Zhong, Zhenyu Bian, Xiang Fang, You Peng & Yongping Hu. (2016) Association between polymorphisms of OGG1, EPHA2 and age-related cataract risk: a meta-analysis. BMC Ophthalmology 16:1.
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Xi Zhu, Guowei Zhang, Lihua Kang & Huaijin Guan. (2015) Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract. Journal of Ophthalmology 2015, pages 1-8.
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The Changes of 8-OHdG, hOGG1, APE1 and Pol β in Lenses of Patients with Age-Related Cataract

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The Changes of 8-OHdG, hOGG1, APE1 and Pol β in Lenses of Patients with Age-Related Cataract

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