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Original Article

Corneal Sensitivity and Tear Function in Neurodegenerative Diseases

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Pages 423-428 | Received 14 Jun 2013, Accepted 28 May 2014, Published online: 23 Jun 2014

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Zhizhang Dong, Ali Luo, Yifeng Gan & Juan Li. (2018) Amyloid Beta Deposition Could Cause Corneal Epithelial Cell Degeneration Associated with Increasing Apoptosis in APPswePS1 Transgenic Mice. Current Eye Research 43:11, pages 1326-1333.
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Alex Suh, Joshua Ong, Sharif Amit Kamran, Ethan Waisberg, Phani Paladugu, Nasif Zaman, Prithul Sarker, Alireza Tavakkoli & Andrew G. Lee. (2023) Retina Oculomics in Neurodegenerative Disease. Annals of Biomedical Engineering 51:12, pages 2708-2721.
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N. B. Chesnokova, T. A. Pavlenko, O. V. Beznos & M. R. Nodel. (2023) Tear fluid as a source of biomarkers for the neurodegeneration in central nervous system. Russian neurological journal 28:5, pages 5-13.
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Pareena Chaitanuwong, Panisa Singhanetr, Methaphon Chainakul, Niracha Arjkongharn, Paisan Ruamviboonsuk & Andrzej Grzybowski. (2023) Potential Ocular Biomarkers for Early Detection of Alzheimer’s Disease and Their Roles in Artificial Intelligence Studies. Neurology and Therapy 12:5, pages 1517-1532.
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Snježana Kaštelan, Marijana Braš, Neda Pjevač, Ivana Bakija, Zora Tomić, Nada Pjevač Keleminić & Antonela Gverović Antunica. (2023) Tear Biomarkers and Alzheimer’s Disease. International Journal of Molecular Sciences 24:17, pages 13429.
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Larisa Ungureanu, K. Ray Chaudhuri, Stefania Diaconu & Cristian Falup-Pecurariu. (2023) Dry eye in Parkinson's disease: a narrative review. Frontiers in Neurology 14.
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Ahsan Hussain, Zahra Sheikh & Manju Subramanian. (2023) The Eye as a Diagnostic Tool for Alzheimer’s Disease. Life 13:3, pages 726.
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Matilde Buzzi, Giuseppe Giannaccare, Michela Cennamo, Federico Bernabei, Pierre-Raphael Rothschild, Aldo Vagge, Vincenzo Scorcia & Rita Mencucci. (2022) Ocular Surface Features in Patients with Parkinson Disease on and off Treatment: A Narrative Review. Life 12:12, pages 2141.
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Ken Nagino, Jaemyoung Sung, Genko Oyama, Motoshi Hayano, Nobutaka Hattori, Yuichi Okumura, Kenta Fujio, Yasutsugu Akasaki, Tianxiang Huang, Akie Midorikawa-Inomata, Keiichi Fujimoto, Atsuko Eguchi, Shokirova Hurramhon, Maria Miura, Mizu Ohno, Kunihiko Hirosawa, Yuki Morooka, Akira Murakami, Hiroyuki Kobayashi & Takenori Inomata. (2022) Prevalence and characteristics of dry eye disease in Parkinson’s disease: a systematic review and meta-analysis. Scientific Reports 12:1.
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Angelika Król-Grzymała, Edyta Sienkiewicz-Szłapka, Ewa Fiedorowicz, Dominika Rozmus, Anna Cieślińska & Andrzej Grzybowski. (2022) Tear Biomarkers in Alzheimer’s and Parkinson’s Diseases, and Multiple Sclerosis: Implications for Diagnosis (Systematic Review). International Journal of Molecular Sciences 23:17, pages 10123.
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Daniel Romaus-Sanjurjo, Uxía Regueiro, Maite López-López, Laura Vázquez-Vázquez, Alberto Ouro, Isabel Lema & Tomás Sobrino. (2022) Alzheimer’s Disease Seen through the Eye: Ocular Alterations and Neurodegeneration. International Journal of Molecular Sciences 23:5, pages 2486.
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Shengguo Li, Shuizhen Shi, Ban Luo, Fan Xia, Yonju Ha, Kevin H. Merkley, Massoud Motamedi, Wenbo Zhang & Hua Liu. (2022) Tauopathy induces degeneration and impairs regeneration of sensory nerves in the cornea. Experimental Eye Research 215, pages 108900.
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Selman Belviranli, Pembe Oltulu, Ali Ulvi Uca, Ali Osman Gundogan, Enver Mirza, Mustafa Altas, Nazli Turk & Refik Oltulu. (2021) Conjunctival impression cytology and tear film parameters in patients with multiple sclerosis. International Ophthalmology 42:2, pages 593-600.
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Mohamad El Haj & Ahmed A. Moustafa. 2022. Alzheimer's Disease. Alzheimer's Disease 77 85 .
Ioannis-Nikolaos Chalkias, Thomas Tegos, Fotis Topouzis & Magda Tsolaki. (2021) Ocular biomarkers and their role in the early diagnosis of neurocognitive disorders. European Journal of Ophthalmology 31:6, pages 2808-2817.
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Ayesha Majeed, Ben Marwick, Haoqing Yu, Hassan Fadavi & Mitra Tavakoli. (2021) Ophthalmic Biomarkers for Alzheimer’s Disease: A Review. Frontiers in Aging Neuroscience 13.
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Hakan Dağıstan & Mehmet Hamamcı. (2021) Nasolacrimal transition time in patients with multiple sclerosis. European Archives of Oto-Rhino-Laryngology 278:9, pages 3357-3362.
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Georges Sukkarieh, Ralph Ghorayeb, Mohamad Issa, Salam Koussa & Naji Waked. (2021) Evaluation of corneal sensitivity in multiple sclerosis patients. Indian Journal of Ophthalmology 69:9, pages 2421.
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Cirous Dehghani, Shaun Frost, Rajiv Jayasena, Christopher Fowler, Colin L. Masters, Yogesan Kanagasingam, Haihan Jiao, Jeremiah K. H. Lim, Holly R. Chinnery & Laura E. Downie. (2020) Morphometric Changes to Corneal Dendritic Cells in Individuals With Mild Cognitive Impairment. Frontiers in Neuroscience 14.
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Haihan Jiao, Laura E. Downie, Xin Huang, Mengliang Wu, Sara Oberrauch, Ryan J. Keenan, Laura H. Jacobson & Holly R. Chinnery. (2020) Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy. Journal of Neuroinflammation 17:1.
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Ajay Ashok, Neena Singh, Suman Chaudhary, Vindhya Bellamkonda, Alexander E Kritikos, Aaron S Wise, Neil Rana, Dallas McDonald & Rithvik Ayyagari. (2020) Retinal Degeneration and Alzheimer’s Disease: An Evolving Link. International Journal of Molecular Sciences 21:19, pages 7290.
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Eva Ausó, Violeta Gómez-Vicente & Gema Esquiva. (2020) Biomarkers for Alzheimer’s Disease Early Diagnosis. Journal of Personalized Medicine 10:3, pages 114.
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Chiara Villa, Marialuisa Lavitrano, Elena Salvatore & Romina Combi. (2020) Molecular and Imaging Biomarkers in Alzheimer’s Disease: A Focus on Recent Insights. Journal of Personalized Medicine 10:3, pages 61.
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Matilde Roda, Carmen Ciavarella, Giuseppe Giannaccare & Piera Versura. (2020) Biomarkers in Tears and Ocular Surface: A Window for Neurodegenerative Diseases. Eye & Contact Lens: Science & Clinical Practice 46:2, pages S129-S134.
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Maria C Edman, Srikanth R Janga, Shruti Singh Kakan, Curtis T Okamoto, Daniel Freire, Danielle Feigenbaum, Mark Lew & Sarah F Hamm-Alvarez. (2020) Tears – more to them than meets the eye: why tears are a good source of biomarkers in Parkinson's disease. Biomarkers in Medicine 14:2, pages 151-163.
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AjayK Singh & Shilpa Verma. (2020) Use of ocular biomarkers as a potential tool for early diagnosis of Alzheimer's disease. Indian Journal of Ophthalmology 68:4, pages 555.
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S.E. Avetisov, A.V. Karabanov, Z.V. Surnina & A.A. Gamidov. (2020) Changes in corneal nerves fibers in the early stages of Parkinson’s disease according to in vivo confocal microscopy (preliminary report). Vestnik oftal'mologii 136:5, pages 191.
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Ilaria Cicalini, Claudia Rossi, Damiana Pieragostino, Luca Agnifili, Leonardo Mastropasqua, Maria di Ioia, Giovanna De Luca, Marco Onofrj, Luca Federici & Piero Del Boccio. (2019) Integrated Lipidomics and Metabolomics Analysis of Tears in Multiple Sclerosis: An Insight into Diagnostic Potential of Lacrimal Fluid. International Journal of Molecular Sciences 20:6, pages 1265.
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Anjali PrasharAnjali Prashar. 2019. Shed Tears for Diagnostics. Shed Tears for Diagnostics 51 84 .
Edward Lum & Paul J. Murphy. (2018) Effects of ambient humidity on the Cochet–Bonnet aesthesiometer. Eye 32:10, pages 1644-1651.
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Pade Colligris, Maria Jesus Perez de Lara, Basilio Colligris & Jesus Pintor. (2018) Ocular Manifestations of Alzheimer’s and Other Neurodegenerative Diseases: The Prospect of the Eye as a Tool for the Early Diagnosis of Alzheimer’s Disease. Journal of Ophthalmology 2018, pages 1-12.
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Ilona Csoti & Paul Lingor. (2018) Trockenes Auge — unterschätzt und unterdiagnostiziert. NeuroTransmitter 29:3, pages 24-29.
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Seden Demirci, Alime Gunes, Hasan Rifat Koyuncuoglu, Levent Tok & Ozlem Tok. (2016) Evaluation of corneal parameters in patients with Parkinson’s disease. Neurological Sciences 37:8, pages 1247-1252.
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Gergő Kalló, Miklós Emri, Zsófia Varga, Bernadett Ujhelyi, József Tőzsér, Adrienne Csutak & Éva Csősz. (2016) Changes in the Chemical Barrier Composition of Tears in Alzheimer’s Disease Reveal Potential Tear Diagnostic Biomarkers. PLOS ONE 11:6, pages e0158000.
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Stephanie M. Cox & Jason J. Nichols. (2015) Association Between Meibomian Gland Testing and Ocular Surface Sensitivity. Cornea 34:10, pages 1187-1192.
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