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Anterior Segment

Recreating the Human Limbal Epithelial Stem Cell Niche with Bioengineered Limbal Crypts

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Pages 1153-1160 | Received 02 Feb 2015, Accepted 13 Sep 2015, Published online: 04 Jan 2016

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Mohammad Soleimani, Kasra Cheraqpour, Raghuram Koganti, Seyed Mahbod Baharnoori & Ali R. Djalilian. (2023) Concise Review: Bioengineering of Limbal Stem Cell Niche. Bioengineering 10:1, pages 111.
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Andres Serrano, Kwaku A. Osei, Marcela Huertas-Bello & Alfonso L. Sabater. (2022) The Potential of Stem Cells as Treatment for Ocular Surface Diseases. Current Ophthalmology Reports 10:4, pages 209-217.
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Lavanya Kalaimani, Bharanidharan Devarajan, Venkatesh Prajna Namperumalsamy, Muthukkaruppan Veerappan, Julie T. Daniels & Gowri Priya Chidambaranathan. (2022) Hsa-miR-143-3p inhibits Wnt-β-catenin and MAPK signaling in human corneal epithelial stem cells. Scientific Reports 12:1.
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Clémence Bonnet, Sheyla González, JoAnn S. Roberts, Sarah Y.T. Robertson, Maxime Ruiz, Jie Zheng & Sophie X. Deng. (2021) Human limbal epithelial stem cell regulation, bioengineering and function. Progress in Retinal and Eye Research 85, pages 100956.
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Naresh Polisetti, Andreas Gießl, Matthias Zenkel, Lukas Heger, Diana Dudziak, Elisabeth Naschberger, Lena Stich, Alexander Steinkasserer, Friedrich E. Kruse & Ursula Schlötzer-Schrehardt. (2021) Melanocytes as emerging key players in niche regulation of limbal epithelial stem cells. The Ocular Surface 22, pages 172-189.
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Veronica Hidalgo-Alvarez, Hala S. Dhowre, Olivia A. Kingston, Carl M. Sheridan & Hannah J. Levis. (2021) Biofabrication of Artificial Stem Cell Niches in the Anterior Ocular Segment. Bioengineering 8:10, pages 135.
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Sohil Amin, Elmira Jalilian, Eitan Katz, Charlie Frank, Ghasem Yazdanpanah, Victor H. Guaiquil, Mark I. Rosenblatt & Ali R. Djalilian. (2021) The Limbal Niche and Regenerative Strategies. Vision 5:4, pages 43.
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Vivek Singh, Anil Tiwari, Abhinav Reddy Kethiri & Virender Singh Sangwan. (2021) Current Perspectives of Limbal-Derived Stem Cells and its Application in Ocular Surface Regeneration and Limbal Stem Cell Transplantation. Stem Cells Translational Medicine 10:8, pages 1121-1128.
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Mohamed Abdul-Al, George Kumi Kyeremeh, Morvarid Saeinasab, Saeed Heidari Keshel & Farshid Sefat. (2021) Stem Cell Niche Microenvironment: Review. Bioengineering 8:8, pages 108.
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Ovidiu Samoila & Lacramioara Samoila. (2021) Stem Cells in the Path of Light, from Corneal to Retinal Reconstruction. Biomedicines 9:8, pages 873.
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Yongqiang Dong, Xudong Wu, Xuerong Chen, Ping Zhou, Fangming Xu & Wenqing Liang. (2021) Nanotechnology shaping stem cell therapy: Recent advances, application, challenges, and future outlook. Biomedicine & Pharmacotherapy 137, pages 111236.
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Ali E. Ghareeb, Majlinda Lako & Francisco C. Figueiredo. (2020) Recent Advances in Stem Cell Therapy for Limbal Stem Cell Deficiency: A Narrative Review. Ophthalmology and Therapy 9:4, pages 809-831.
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Anna R. O’Callaghan, Marc A. Dziasko, Radhika Sheth‐Shah, Mark P. Lewis & Julie T. Daniels. (2020) Oral Mucosa Tissue Equivalents for the Treatment of Limbal Stem Cell Deficiency. Advanced Biosystems 4:7, pages 1900265.
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Mohammadmahdi Mobaraki, Reza Abbasi, Sajjad Omidian Vandchali, Maryam Ghaffari, Fathollah Moztarzadeh & Masoud Mozafari. (2019) Corneal Repair and Regeneration: Current Concepts and Future Directions. Frontiers in Bioengineering and Biotechnology 7.
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Michel Haagdorens, Vytautas Cėpla, Eline Melsbach, Laura Koivusalo, Heli Skottman, May Griffith, Ramūnas Valiokas, Nadia Zakaria, Isabel Pintelon & Marie-José Tassignon. (2019) In Vitro Cultivation of Limbal Epithelial Stem Cells on Surface-Modified Crosslinked Collagen Scaffolds. Stem Cells International 2019, pages 1-17.
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Ghasem Yazdanpanah, Zeeshan Haq, Kai Kang, Sayena Jabbehdari, Mark l Rosenblatt & Ali R. Djalilian. (2019) Strategies for reconstructing the limbal stem cell niche. The Ocular Surface 17:2, pages 230-240.
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Ghasem Yazdanpanah, Sayena Jabbehdari & Ali R. Djalilian. (2019) Emerging Approaches for Ocular Surface Regeneration. Current Ophthalmology Reports 7:1, pages 1-10.
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Valentina Barrera, Lee D. Troughton, Valentina Iorio, Siyin Liu, Olutobi Oyewole, Carl M. Sheridan & Kevin J. Hamill. (2018) Differential Distribution of Laminin N-Terminus α31 Across the Ocular Surface: Implications for Corneal Wound Repair. Investigative Opthalmology & Visual Science 59:10, pages 4082.
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Zhi Guo, Wei Zhang, Yang Jia, Qing Liu, Zhao Li & Jun Lin. (2018) An Insight into the Difficulties in the Discovery of Specific Biomarkers of Limbal Stem Cells. International Journal of Molecular Sciences 19:7, pages 1982.
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Golnar Shojaati, Irona Khandaker, Kyle Sylakowski, Martha L. Funderburgh, Yiqin Du & James L. Funderburgh. (2018) Compressed Collagen Enhances Stem Cell Therapy for Corneal Scarring. Stem Cells Translational Medicine 7:6, pages 487-494.
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Rachel Williams, Rebecca Lace, Stephnie Kennedy, Kyle Doherty & Hannah Levis. (2018) Biomaterials for Regenerative Medicine Approaches for the Anterior Segment of the Eye. Advanced Healthcare Materials 7:10, pages 1701328.
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Solja Kalha, Bideep Shrestha, Maria Sanz Navarro, Kyle B. Jones, Ophir D. Klein & Frederic Michon. (2018) Bmi1+ Progenitor Cell Dynamics in Murine Cornea During Homeostasis and Wound Healing . Stem Cells 36:4, pages 562-573.
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Saeed Farzamfar, Niloofar Nazeri, Majid Salehi, Alireza Valizadeh, Sayed Mahdi Marashi, Gholamreza Savari Kouzehkonan & Hossein Ghanbari. (2018) Will Nanotechnology Bring New Hope for Stem Cell Therapy?. Cells Tissues Organs 206:4-5, pages 229-241.
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Kim N. Nguyen, Samantha Bobba, Alexander Richardson, Mijeong Park, Stephanie L. Watson, Denis Wakefield & Nick Di Girolamo. (2018) Native and synthetic scaffolds for limbal epithelial stem cell transplantation. Acta Biomaterialia 65, pages 21-35.
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Djida Ghoubay-Benallaoua, Céline de Sousa, Raphaël Martos, Gaël Latour, Marie-Claire Schanne-Klein, Elisabeth Dupin & Vincent Borderie. (2017) Easy xeno-free and feeder-free method for isolating and growing limbal stromal and epithelial stem cells of the human cornea. PLOS ONE 12:11, pages e0188398.
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Naresh Polisetti, Lydia Sorokin, Naoki Okumura, Noriko Koizumi, Shigeru Kinoshita, Friedrich E. Kruse & Ursula Schlötzer-Schrehardt. (2017) Laminin-511 and -521-based matrices for efficient ex vivo-expansion of human limbal epithelial progenitor cells. Scientific Reports 7:1.
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J. Behaegel, S. Ní Dhubhghaill, C. Koppen & N. Zakaria. (2017) Safety of Cultivated Limbal Epithelial Stem Cell Transplantation for Human Corneal Regeneration. Stem Cells International 2017, pages 1-11.
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