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Current Eye Research Volume 4, 1985 - Issue 12
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Original Article

The effect of H2O2 on lens epithelial cell glutathione

Abraham Spector Biochemistry and Molecular Biology Laboratory, Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA
,
Ruey-Ruey C. Huang Biochemistry and Molecular Biology Laboratory, Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA
&
Guo-Ming Wang Biochemistry and Molecular Biology Laboratory, Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA
Pages 1289-1295 | Received 23 Sep 1985, Accepted 07 Nov 1985, Published online: 02 Jul 2009

Citations (20)

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Norman J. Kleiman, Ren-Rong Wang & Abraham Spector. (1990) Ultraviolet light induced DNA damage and repair in bovine lens epithelial cells. Current Eye Research 9:12, pages 1185-1193.
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Articles from other publishers (19)

Judith West-Mays & Scott Bowman. 2016. Animal Models of Ophthalmic Diseases. Animal Models of Ophthalmic Diseases 11 29 .
Zhuo Wang, Dan Wang, Yan Li & Xiuli Zhang. (2014) Protective Effects of Verapamil against H 2 O 2 -Induced Apoptosis in Human Lens Epithelial Cells . Biomolecules & Therapeutics 22:6, pages 553-557.
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Martin Kronschläger, Stefan Löfgren, Zhaohua Yu, Nooshin Talebizadeh, Shambhu D. Varma & Per Söderberg. (2013) Caffeine eye drops protect against UV-B cataract. Experimental Eye Research 113, pages 26-31.
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Siling Wang, Jing Zhang, Tongying Jiang, Li Zheng, Zhanyou Wang, Jinghai Zhang & Pan Yu. (2011) Protective effect of Coenzyme Q10 against oxidative damage in human lens epithelial cells by novel ocular drug carriers. International Journal of Pharmaceutics 403:1-2, pages 219-229.
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Cornelius F.H. MuellerJulian D. WidderJoseph S. McNallyLouise McCannDean P. JonesDavid G. Harrison. (2005) The Role of the Multidrug Resistance Protein-1 in Modulation of Endothelial Cell Oxidative Stress. Circulation Research 97:7, pages 637-644.
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. (2004) Abraham Spector Bibliography. Experimental Eye Research 79:6, pages 741-745.
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Oddbjørn Sæther, Øystein Risa, Jitka Čejková, Jostein Krane & Anna Midelfart. (2004) High-resolution magic angle spinning 1H NMR spectroscopy of metabolic changes in rabbit lens after treatment with dexamethasone combined with UVB exposure. Graefe's Archive for Clinical and Experimental Ophthalmology 242:12, pages 1000-1007.
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John R. Reddan, Frank J. Giblin, Michael Sevilla, Vanita Padgaonkar, Dorothy C. Dziedzic, Victor R. Leverenz, Indira C. Misra, Justin S. Chang & John T. Pena. (2003) Propyl gallate is a superoxide dismutase mimic and protects cultured lens epithelial cells from H2O2 insult. Experimental Eye Research 76:1, pages 49-59.
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R. M. Jain & P. M. Bulakh. (2003) Effect of ketoacids on H2O2 induced cataract. Indian Journal of Clinical Biochemistry 18:1, pages 91-95.
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Kenneth Hightower & Janet McCready. (2008) The Role of Calcium in UVB‐lnduced Damage in Irradiated Ocular Lenses. Photochemistry and Photobiology 65:1, pages 155-160.
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Margaret H. Garner, Afshin Bahador, Bao-Thu Thi Nguyen, Ren-Rong Wang & Abraham Spector. (1992) Na,K-ATPase of cultured bovine lens epithelial cells: H2O2 effects. Experimental Eye Research 54:3, pages 321-328.
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Nanyong Yuan & Donald G. Pitts. (2009) Residual H 2 O 2 compromises deswelling function of in vivo rabbit cornea . Acta Ophthalmologica 69:2, pages 241-246.
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Norman J. Kleiman, Ren-Rong Wang & Abraham Spector. (1990) Hydrogen peroxide-induced DNA damage in bovine lens epithelial cells. Mutation Research/Genetic Toxicology 240:1, pages 35-45.
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Abraham Spector, Norman J. Kleiman, Ruey-Ruey C. Huang & Ren-Rong Wang. (1989) Repair of H2O2-induced DNA damage in bovine lens epithelial cell cultures. Experimental Eye Research 49:4, pages 685-698.
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John S. Hothersall, C.Emyln Taylaur & Patricia McLean. (1988) Antioxidant status in an in vitro model for hyperglycemic lens cataract formation: Effect of aldose reductase inhibitor statil. Biochemical Medicine and Metabolic Biology 40:2, pages 109-117.
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Christopher J. Bates & Terence D. Cowen. (1988) Effects of age and dietary vitamin C on the contents of ascorbic acid and acid-soluble thiol in lens and aqueous humour of guinea-pigs. Experimental Eye Research 46:6, pages 937-945.
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Simon P. Wolff & Abraham Spector. (1987) Pro-oxidant activation of ocular reductants. 2. Lens epithelial cell cytotoxicity of a dietary quinone is associated with a stable free radical formed with glutathione in vitro. Experimental Eye Research 45:6, pages 791-803.
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Simon P. Wolff, Guo-Ming Wang & Abraham Spector. (1987) Pro-oxidant activation of ocular reductants. 1. Copper and riboflavin stimulate ascorbate oxidation causing lens epithelial cytotoxicity in vitro. Experimental Eye Research 45:6, pages 777-789.
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Abraham Spector, Ruey-Ruey C. Huang, Guo-Ming Wang, Charles Schmidt, Guo-Zai Yan & Silvia Chifflet. (1987) Does elevated glutathione protect tl cell from H2O2 insult?. Experimental Eye Research 45:3, pages 453-465.
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