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Current Eye Research Volume 6, 1987 - Issue 11
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Original Article

Ocular Effects of a N,N-Disubstituted 5-OH Aminotetralin (N-0437): Evidence for a Dual Mechanism of Action

Craig E. Crosson Department of Ophthalmology, University of California, Irvine, CA, 92717, USA
,
James A. Burke Department of Pharmacology, Discovery Research, Allergan Inc., Irvine, CA, 92715, USA
,
Ming-Fai Chan Department of Pharmacology, Discovery Research, Allergan Inc., Irvine, CA, 92715, USA
&
David E. Potter Department of Ophthalmology, University of California, Irvine, CA, 92717, USA; Center for Biotechnology, Baylor School of Medicine, 4000 Research Forest Drive, The Woodlands, TX, 77381, USA
Pages 1319-1326 | Received 15 Jul 1987, Accepted 30 Sep 1987, Published online: 02 Jul 2009

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T. K. Gerding, B. F. H. Drenth, H. J. Roosenstein, R. A. De Zeeuw, P. G. Tepper & A. S. Horn. (1990) The metabolic fate of the dopamine agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin in rats after intravenous and oral administration I. Disposition and metabolic profiling. Xenobiotica 20:5, pages 515-524.
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P. P. Elena, P. Denis, M. Kosina-Boix & P. Lapalus. (1989) Dopamine receptors in rabbit and rat eye: characterization and localization of DA1 and DA2 binding sites. Current Eye Research 8:1, pages 75-83.
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Articles from other publishers (9)

Sara M. Thomasy. 2022. Wild and Exotic Animal Ophthalmology. Wild and Exotic Animal Ophthalmology 483 543 .
Chiara Bianca Maria Platania, Gian Marco Leggio, Filippo Drago, Salvatore Salomone & Claudio Bucolo. (2013) Regulation of intraocular pressure in mice: Structural analysis of dopaminergic and serotonergic systems in response to cabergoline. Biochemical Pharmacology 86:9, pages 1347-1356.
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Claudio Bucolo, Gian Marco Leggio, Adriana Maltese, Alessandro Castorina, Velia D’Agata & Filippo Drago. (2012) Dopamine-3 receptor modulates intraocular pressure: Implications for glaucoma. Biochemical Pharmacology 83:5, pages 680-686.
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Najam A. Sharif, Marsha A. McLaughlin, Curtis R. Kelly, Parvaneh Katoli, Colene Drace, Shahid Husain, Craig Crosson, Carol Toris, Gui-Lin Zhan & Carl Camras. (2009) Cabergoline: Pharmacology, ocular hypotensive studies in multiple species, and aqueous humor dynamic modulation in the Cynomolgus monkey eyes. Experimental Eye Research 88:3, pages 386-397.
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Andrey Leonov & Leonard Bielory. (2007) Chirality in ocular agents. Current Opinion in Allergy & Clinical Immunology 7:5, pages 418-423.
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T.K. Gerding, B.F.H. Drenth, R.A. de Zeeuw, A.S. Horn, J.L. van Delft & J.A. Oosterhuis. (1990) Ocular and systemic disposition of the dopamine agonist N-0437 in monkeys after ocular administration. Experimental Eye Research 51:1, pages 11-14.
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D. E. Potter, J. A. Burke & M. J. Ogidigben. (2008) Ocular inhibitory effects of the dopamine DA 2 agonist (Ha‐118) in cats and rabbits . Journal of Autonomic Pharmacology 10:3, pages 153-162.
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Craig E. Crosson, James A. Burke, Ming Fai Chan & David E. Potter. (1990) Prejunctional adrenoceptor activity of N-0437: a relatively selective DA2 dopamine receptor agonist. European Journal of Pharmacology 178:3, pages 351-355.
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Michael F. Sugrue. (1989) The pharmacology of antiglaucoma drugs. Pharmacology & Therapeutics 43:1, pages 91-138.
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