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Current Eye Research Volume 11, 1992 - Issue sup1
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Review Article

Experimental autoimmune uveoretinitis: a model system for immunointervention: a review

J. V. Forrester Department of Ophthalmology, University of Aberdeen, Medical School, Foresterhill, Aberdeen, AB9 2ZD, UK
,
Janet Liversidge Department of Ophthalmology, University of Aberdeen, Medical School, Foresterhill, Aberdeen, AB9 2ZD, UK
,
H. S. Dua Department of Ophthalmology, University of Aberdeen, Medical School, Foresterhill, Aberdeen, AB9 2ZD, UK
,
A. Dick Department of Ophthalmology, University of Aberdeen, Medical School, Foresterhill, Aberdeen, AB9 2ZD, UK
,
Fiona Harper Department of Ophthalmology, University of Aberdeen, Medical School, Foresterhill, Aberdeen, AB9 2ZD, UK
&
P. G. McMenamin Department of Anatomy and Human Biology, University of Western Australia, Nedlands, Perth, Western Australia, 6009
Pages 33-40 | Received 17 Jan 1992, Accepted 08 May 1992, Published online: 02 Jul 2009

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John V Forrester, Izabela P. Klaska, Tian Yu & Lucia Kuffova. (2013) Uveitis in Mouse and Man. International Reviews of Immunology 32:1, pages 76-96.
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Michael R. Niesman, Ming Ni & Jeffrey N. Bloom. (1998) Liposome-Encapsulated Clodronate Retards the Development of Experimental Autoimmune Uveitis. Journal of Liposome Research 8:3, pages 367-379.
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John V. Forrester, Inge Huitinga, Lynne Lumsden & Christine D. Dijkstra. (1998) Marrow-derived activated macrophages are required during the effector phase of experimental autoimmune uveoretinitis in rats. Current Eye Research 17:4, pages 426-437.
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Harminder Singh Dua, Larry A. Donoso & Peter R. Laibson. (1994) Conjunctival instillation of retinal antigens induces tolerance Does it invoke mucosal tolerance mediated via conjunctiva associated lymphoid tissues (CALT)?. Ocular Immunology and Inflammation 2:1, pages 29-36.
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Janet Liversidge, Andrew Dick, Ying-Feng Cheng, Geoffrey B. Scott & John V. Forrester. (1993) Retinal Antigen Specific Lymphocytes, Tcr-Gamma Delta T Cells and Cd5+ B Cells Cultured from the Vitreous in Acute Sympathetic Ophthalmitis. Autoimmunity 15:4, pages 257-266.
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Articles from other publishers (39)

Avik Shome, Odunayo O. Mugisho, Rachael L. Niederer & Ilva D. Rupenthal. (2021) Blocking the inflammasome: A novel approach to treat uveitis. Drug Discovery Today 26:12, pages 2839-2857.
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Mei Chen, Jiawu Zhao, Imran H.A. Ali, Stephen Marry, Josy Augustine, Mohajeet Bhuckory, Aisling Lynch, Adrien Kissenpfennig & Heping Xu. (2018) Cytokine Signaling Protein 3 Deficiency in Myeloid Cells Promotes Retinal Degeneration and Angiogenesis through Arginase-1 Up-Regulation in Experimental Autoimmune Uveoretinitis. The American Journal of Pathology 188:4, pages 1007-1020.
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Maren Kasper, Doris Gabriel, Michael Möller, Dirk Bauer, Lena Wildschütz, Herve Courthion, Michael R.R. Böhm, Martin Busch, Karin Loser, Solon Thanos, Robert Gurny & Arnd Heiligenhaus. (2018) Novel everolimus-loaded nanocarriers for topical treatment of murine experimental autoimmune uveoretinitis (EAU). Experimental Eye Research 168, pages 49-56.
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Heping Xu & Mei Chen. (2016) Targeting the complement system for the management of retinal inflammatory and degenerative diseases. European Journal of Pharmacology 787, pages 94-104.
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Svati Bansal, VeluchamyA Barathi, Daiju Iwata & Rupesh Agrawal. (2015) Experimental autoimmune uveitis and other animal models of uveitis: An update. Indian Journal of Ophthalmology 63:3, pages 211.
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Kohzou Harimoto, Masataka Ito, Yoko Karasawa, Yutaka Sakurai & Masaru Takeuchi. (2014) Evaluation of mouse experimental autoimmune uveoretinitis by spectral domain optical coherence tomography. British Journal of Ophthalmology 98:6, pages 808-812.
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Jun Chen, Haohua Qian, Reiko Horai, Chi-Chao Chan, Yishay Falick & Rachel R. Caspi. (2013) Comparative Analysis of Induced vs. Spontaneous Models of Autoimmune Uveitis Targeting the Interphotoreceptor Retinoid Binding Protein. PLoS ONE 8:8, pages e72161.
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Chang Luo, Jiawu Zhao, Angelina Madden, Mei Chen & Heping Xu. (2013) Complement expression in retinal pigment epithelial cells is modulated by activated macrophages. Experimental Eye Research 112, pages 93-101.
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Jun Chen, Haohua Qian, Reiko Horai, Chi-Chao Chan & Rachel R. Caspi. (2013) Use of Optical Coherence Tomography and Electroretinography to Evaluate Retinal Pathology in a Mouse Model of Autoimmune Uveitis. PLoS ONE 8:5, pages e63904.
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Cheng-Rong Yu, Yun Sang Lee, Rashid M. Mahdi, Narayanan Surendran & Charles E. Egwuagu. (2012) Therapeutic Targeting of STAT3 (Signal Transducers and Activators of Transcription 3) Pathway Inhibits Experimental Autoimmune Uveitis. PLoS ONE 7:1, pages e29742.
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Mei Chen, David A. Copland, Jiawu Zhao, Jian Liu, John V. Forrester, Andrew D. Dick & Heping Xu. (2012) Persistent Inflammation Subverts Thrombospondin-1–Induced Regulation of Retinal Angiogenesis and Is Driven by CCR2 Ligation. The American Journal of Pathology 180:1, pages 235-245.
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Mei Chen, Elizabeth Muckersie, Chang Luo, John V. Forrester & Heping Xu. (2010) Inhibition of the alternative pathway of complement activation reduces inflammation in experimental autoimmune uveoretinitis. European Journal of Immunology 40:10, pages 2870-2881.
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Ben J. E. Raveney, David A. Copland, Andrew D. Dick & Lindsay B. Nicholson. (2009) TNFR1-Dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis. The Journal of Immunology 183:4, pages 2321-2329.
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C Fujimoto, D M Klinman, G Shi, H Yin, B P Vistica, J D Lovaas, E F Wawrousek, T Igarashi, C-C Chan & I Gery. (2009) A suppressive oligodeoxynucleotide inhibits ocular inflammation. Clinical and Experimental Immunology 156:3, pages 528-534.
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Heping Xu, Philippe Koch, Mei Chen, Annie Lau, Delyth M. Reid & John V. Forrester. (2008) A clinical grading system for retinal inflammation in the chronic model of experimental autoimmune uveoretinitis using digital fundus images. Experimental Eye Research 87:4, pages 319-326.
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A W THOMSON & J V FORRESTER. (1994) Therapeutic advances in immunosuppression. Clinical and Experimental Immunology 98:3, pages 351-357.
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Doran B. Spencer, Ellen J. Lee, Tatsushi Kawaguchi & James T. Rosenbaum. (2008) In vivo imaging of the immune response in the eye. Seminars in Immunopathology 30:2, pages 179-190.
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Isabel J. Crane & Janet Liversidge. (2008) Mechanisms of leukocyte migration across the blood–retina barrier. Seminars in Immunopathology 30:2, pages 165-177.
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Heping Xu, Ching L Cheng, Mei Chen, Ayyakkannu Manivannan, Laurence Cabay, Roger G Pertwee, Angela Coutts & John V Forrester. (2007) Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis. Journal of Leukocyte Biology 82:3, pages 532-541.
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Ralph Feuer. (2007) Tickling the CD200 Receptor. The American Journal of Pathology 171:2, pages 396-398.
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Heping Xu, Ayyakkannu Manivannan, Rosemary Dawson, Isabel J. Crane, Matthias Mack, Peter Sharp & Janet Liversidge. (2005) Differentiation to the CCR2 + Inflammatory Phenotype In Vivo Is a Constitutive, Time-Limited Property of Blood Monocytes and Is Independent of Local Inflammatory Mediators . The Journal of Immunology 175:10, pages 6915-6923.
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Andrew D. Dick, John V. Forrester, Janet Liversidge & Andrew P. Cope. (2004) The role of tumour necrosis factor (TNF-α) in experimental autoimmune uveoretinitis (EAU). Progress in Retinal and Eye Research 23:6, pages 617-637.
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Heping Xu, Ayyakkannu Manivannan, Hui-Rong Jiang, Janet Liversidge, Peter F. Sharp, John V. Forrester & Isabel J. Crane. (2004) Recruitment of IFN-γ-Producing (Th1-Like) Cells into the Inflamed Retina In Vivo Is Preferentially Regulated by P-Selectin Glycoprotein Ligand 1:P/E-Selectin Interactions. The Journal of Immunology 172:5, pages 3215-3224.
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Heping Xu, Ayyakkannu Manivannan, Keith A Goatman, Hui-Rong Jiang, Janet Liversidge, Peter F Sharp, John V Forrester & Isabel J Crane. (2004) Reduction in shear stress, activation of the endothelium, and leukocyte priming are all required for leukocyte passage across the blood—retina barrier. Journal of Leukocyte Biology 75:2, pages 224-232.
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Andrew D Dick, Debra Carter, Morag Robertson, Cathryn Broderick, Edward Hughes, John V Forrester & Janet Liversidge. (2003) Control of myeloid activity during retinal inflammation. Journal of Leukocyte Biology 74:2, pages 161-166.
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F.H. Grus, A.J. Augustin, K. Loeffler, J. Lutz & N. Pfeiffer. (2018) Immunological Effects of Allopurinol in the Treatment of Experimental Autoimmune Uveitis (EAU) after Onset of the Disease. European Journal of Ophthalmology 13:2, pages 185-191.
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Heping Xu, Ayyakkannu Manivannan, Janet Liversidge, Peter F Sharp, John V Forrester & Isabel J Crane. (2002) Involvement of CD44 in leukocyte trafficking at the blood-retinal barrier. Journal of Leukocyte Biology 72:6, pages 1133-1141.
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F.H. Grus, A.J. Augustin, K. Loeffler, B. Dick, J. Lutz & N. Pfeiffer. (2018) Allopurinol has Immunomodulating Activity following Topical and Systemic Application in Experimental Autoimmune Uveitis. European Journal of Ophthalmology 11:3, pages 252-260.
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Monique P Gelderman, Federico Gonzalez-Fernandez, Claxton A Baer, Barbara Wiggert, Chi-Chao Chan, Barbara P Vistica & Igal Gery. (2000) Xenopus IRBP, a Phylogenetically Remote Protein, is Uveitogenic in Lewis Rats. Experimental Eye Research 70:6, pages 731-736.
Crossref
S.A. Vinores, C.-C. Chan, M.A. Vinores, D.M. Matteson, Y.-S. Chen, D.A. Klein, A. Shi, H. Ozaki & P.A. Campochiaro. (1998) Increased vascular endothelial growth factor (VEGF) and transforming growth factorβ (TGF ) in experimental autoimmune uveoretinitis: upregulation of VEGF without neovascularization. Journal of Neuroimmunology 89:1-2, pages 43-50.
Crossref
Bernhard Kreutzer, Barbara Laliotou, Y F Cheng, Janet Liversidge, John V Forrester & Andrew D Dick. (1997) Nasal administration of retinal antigens maintains immunosuppression of uveoretinitis in cyclosporin-a-treated lewis rats: Future treatment of endogenous posterior uveoretinitis?. Eye 11:4, pages 445-452.
Crossref
JOSE A.P GOMES, VINOD K JINDAL, PAULA D GORMLEY & HARMINDER S DUA. (1997) Phenotypic Analysis of Resident Lymphoid Cells in the Conjunctiva and Adnexal Tissues of Rat. Experimental Eye Research 64:6, pages 991-997.
Crossref
P R Richardson, M E Boulton, J Duvall-Young & D McLeod. (1996) Immunocytochemical study of retinal diode laser photocoagulation in the rat.. British Journal of Ophthalmology 80:12, pages 1092-1098.
Crossref
H S Dua, V K Jindal, J A P Gomes, W A Amoaku, L A Donoso, P R Laibson & K Mahlberg. (1996) The effect of topical cyclosporin on conjunctiva-associated lymphoid tissue (CALT). Eye 10:4, pages 433-438.
Crossref
Harminder S Dua, Jose A P Gomes, Larry A Donoso & Peter R Laibson. (1995) The ocular surface as part of the mucosal immune system: Conjunctival mucosa-specific lymphocytes in ocular surface pathology. Eye 9:3, pages 261-267.
Crossref
John V. Forrester, Lynne Lumsden, Janet Liversidge, Maria Kuppner & Mehdi Mesri. (1995) Immunoregulation of uveoretinal inflammation. Progress in Retinal and Eye Research 14:2, pages 393-412.
Crossref
Amitabh Gaur & C. Garrison Fathman. 1994. Advances in Immunology Volume 56. Advances in Immunology Volume 56 219 265 .
P.G. McMenamin, R.M. Broekhuyse & J.V. Forrester. (1993) Ultrastructural pathology of experimental autoimmune uveitis: A review. Micron 24:5, pages 521-546.
Crossref
John V Forrester. (1992) New concepts on the role of autoimmunity in the pathogenesis of uveitis. Eye 6:5, pages 433-446.
Crossref

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