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Current Eye Research Volume 13, 1994 - Issue 12
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Original Article

The effect of a modified β-cyclodextrin, SBE4-β-CD, on the aqueous stability and ocular absorption of pilocarpine

Kristiina Järvinen Department of Pharmaceutical Chemistry and Center for Drug Delivery Research, The University of Kansas, Lawrence, KS, USA; Department of Pharmaceutical Technology, The University of Kuopio, Kansas City, KS, USA
,
Tomi Järvinen Department of Pharmaceutical Chemistry and Center for Drug Delivery Research, The University of Kansas, Lawrence, KS, USA; Department of Chemistry, The University of Kuopio, Finland
,
Diane O. Thompson Department of Pharmaceutical Chemistry and Center for Drug Delivery Research, The University of Kansas, Lawrence, KS, USA; CyDex, L.C., Kansas City, KS, USA
&
Valentino J. Stella Department of Pharmaceutical Chemistry and Center for Drug Delivery Research, The University of Kansas, Lawrence, KS, USA; CyDex, L.C., Kansas City, KS, USA
Pages 897-905 | Published online: 02 Jul 2009

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A.L. Laza-Knoerr, R. Gref & P. Couvreur. (2010) Cyclodextrins for drug delivery. Journal of Drug Targeting 18:9, pages 645-656.
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Yeşim Aktaş, Nurşen Ünlü, Mehmet Orhan, Murat İrkeç & A. Atilla Hıncal. (2003) Influence of Hydroxypropyl β-Cyclodextrin on the Corneal Permeation of Pilocarpine. Drug Development and Industrial Pharmacy 29:2, pages 223-230.
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T. Loftsson & E. Stefánsson. (1997) Effect of Cyclodextrins on Topical Drug Delivery to the Eye. Drug Development and Industrial Pharmacy 23:5, pages 473-481.
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David W. Pate, Kristiina Järvinen, Arto Urtti, Pekka Jarho & Tomi Järvinen. (1995) Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits. Current Eye Research 14:9, pages 791-797.
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Articles from other publishers (38)

Beeran B. Meghpara, Jimmy K. Lee, Christopher J. Rapuano, Shahzad I. Mian & Allen C. Ho. (2022) Pilocarpine 1.25% and the changing landscape of presbyopia treatment. Current Opinion in Ophthalmology.
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Heybet Kerem PolatNihat Kurt, Eren AytekinYagmur Akdağ ÇaylıSibel Bozdağ PehlivanSema Çalış. (2022) Design of Besifloxacin HCl-Loaded Nanostructured Lipid Carriers: In Vitro and Ex Vivo Evaluation . Journal of Ocular Pharmacology and Therapeutics.
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Abu Zayed Md Badruddoza, Thean Yeoh & Jaymin C. Shah. (2022) API-polymer interactions in Sepineo P600 based topical gel formulation- impact on rheology. International Journal of Pharmaceutics 621, pages 121824.
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Gaurav Kant Saraogi, Siddharth Tholiya, Yachana Mishra, Vijay Mishra, Aqel Albutti, Pallavi Nayak & Murtaza M. Tambuwala. (2022) Formulation Development and Evaluation of Pravastatin-Loaded Nanogel for Hyperlipidemia Management. Gels 8:2, pages 81.
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Ammar Said Suliman, Mouhamad Khoder, Ibrahim Tolaymat, Matt Webster, Raid G. Alany, Weiguang Wang, Abdelbary Elhissi & Mohammad Najlah. (2021) Cyclodextrin Diethyldithiocarbamate Copper II Inclusion Complexes: A Promising Chemotherapeutic Delivery System against Chemoresistant Triple Negative Breast Cancer Cell Lines. Pharmaceutics 13:1, pages 84.
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Priya Dhiman & Meenakshi Bhatia. (2020) Pharmaceutical applications of cyclodextrins and their derivatives. Journal of Inclusion Phenomena and Macrocyclic Chemistry 98:3-4, pages 171-186.
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Thorsteinn Loftsson & Einar Stefánsson. (2017) Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eye. International Journal of Pharmaceutics 531:2, pages 413-423.
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Vasanti Suvarna, Parul Gujar & Manikanta Murahari. (2017) Complexation of phytochemicals with cyclodextrin derivatives – An insight. Biomedicine & Pharmacotherapy 88, pages 1122-1144.
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Sachin S. Thakur, Harendra S. Parekh, Carl H. Schwable, Yong Gan & Defang Ouyang. 2015. Computational Pharmaceutics. Computational Pharmaceutics 31 51 .
Annika Tuomela, Peng Liu, Jooseppi Puranen, Seppo Rönkkö, Timo Laaksonen, Giedrius Kalesnykas, Olli Oksala, Jukka Ilkka, Johanna Laru, Kristiina Järvinen, Jouni Hirvonen & Leena Peltonen. (2014) Brinzolamide nanocrystal formulations for ophthalmic delivery: Reduction of elevated intraocular pressure in vivo. International Journal of Pharmaceutics 467:1-2, pages 34-41.
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Hassan A. Abd El-Rehim, Ahmed E. Swilem, Anke Klingner, El-Sayed A. Hegazy & Ashraf A. Hamed. (2013) Developing the Potential Ophthalmic Applications of Pilocarpine Entrapped Into Polyvinylpyrrolidone–Poly(acrylic acid) Nanogel Dispersions Prepared By γ Radiation. Biomacromolecules 14:3, pages 688-698.
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Ariana Zoppi, Yamila Garro Linck, Gustavo A. Monti, Diego B. Genovese, Álvaro F. Jimenez Kairuz, Rubén H. Manzo & Marcela R. Longhi. (2012) Studies of pilocarpine:carbomer intermolecular interactions. International Journal of Pharmaceutics 427:2, pages 252-259.
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Thorsteinn Loftsson & Marcus E Brewster. (2011) Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes. Journal of Pharmacy and Pharmacology 63:9, pages 1119-1135.
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Shayne Cox GadIlva D. Rupenthal & Raid G. Alany. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Valentino J. Stella & Quanren He. (2008) Cyclodextrins. Toxicologic Pathology 36:1, pages 30-42.
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Basavaraj K. Nanjawade, F.V. Manvi & A.S. Manjappa. (2007) RETRACTED: In situ-forming hydrogels for sustained ophthalmic drug delivery. Journal of Controlled Release 122:2, pages 119-134.
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T. Loftsson & E. Stefánsson. (2007) Cyclodextrins in ocular drug delivery: theoretical basis with dexamethasone as a sample drug. Journal of Drug Delivery Science and Technology 17:1, pages 3-9.
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Tomi Järvinen, David W Pate & Krista Laine. (2002) Cannabinoids in the treatment of glaucoma. Pharmacology & Therapeutics 95:2, pages 203-220.
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Thorsteinn Loftsson & Einar Stefánsson. (2003) Cyclodextrins in eye drop formulations: enhanced topical delivery of corticosteroids to the eye. Acta Ophthalmologica Scandinavica 80:2, pages 144-150.
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Michael J. Akers, Vasu Vasudevan & Mary Stickelmeyer. 2002. Development and Manufacture of Protein Pharmaceuticals. Development and Manufacture of Protein Pharmaceuticals 47 127 .
Thorsteinn Loftsson & Mar Masson. (2001) Cyclodextrins in topical drug formulations: theory and practice. International Journal of Pharmaceutics 225:1-2, pages 15-30.
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BURKHARD SIEFERT, UWE PLEYER, MARTINA MÜLLER, CHRISTIAN HARTMANN & SIGRID KEIPERT. (1999) Influence of Cyclodextrins on the In Vitro Corneal Permeability and In Vivo Ocular Distribution of Thalidomide . Journal of Ocular Pharmacology and Therapeutics 15:5, pages 429-438.
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M. Echezarreta-López, T. Esclusa-Díaz, J. L. Vila-Jato & J. J. Torres-Labandeira. 1999. Proceedings of the Ninth International Symposium on Cyclodextrins. Proceedings of the Ninth International Symposium on Cyclodextrins 437 440 .
Kaneto Uekama, Fumitoshi Hirayama & Tetsumi Irie. (1998) Cyclodextrin Drug Carrier Systems. Chemical Reviews 98:5, pages 2045-2076.
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Gilles Dollo, Diane O Thompson, Pascal Le Corre, François Chevanne & Roger Le Verge. (1998) Inclusion complexation of amide-typed local anesthetics with β-cyclodextrin and its derivatives. III. Biopharmaceutics of bupivacaine-SBE7-βCD complex following percutaneous sciatic nerve administration in rabbits. International Journal of Pharmaceutics 164:1-2, pages 11-19.
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Chrystèle Le Bourlais, Liliane Acar, Hosein Zia, Pierre A. Sado, Thomas Needham & Roger Leverge. (1998) Ophthalmic drug delivery systems—Recent advances. Progress in Retinal and Eye Research 17:1, pages 33-58.
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Nigel M Davies, Guangji Wang & Ian G Tucker. (1997) Evaluation of a hydrocortisone/hydroxypropyl-β-cyclodextrin solution for ocular drug delivery. International Journal of Pharmaceutics 156:2, pages 201-209.
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Burkhard Siefert & Sigrid Keipert. (1997) Influence of Alpha-Cyclodextrin and Hydroxyalkylated β-Cyclodextrin Derivatives on the In Vitro Corneal Uptake and Permeation of Aqueous Pilocarpine-HCl Solutions. Journal of Pharmaceutical Sciences 86:6, pages 716-720.
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Ernestina A. Luna, David G. Vander Velde, Russell J. Tait, Diane O. Thompson, Roger A. Rajewski & Valentino J. Stella. (1997) Isolation and characterization by NMR spectroscopy of three monosubstituted 4-sulfobutyl ether derivatives of cyclomaltoheptaose (β-cyclodextrin). Carbohydrate Research 299:3, pages 111-118.
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Ernestina A. Luna, Esteban R.N. Bornancini, Diane O. Thompson, Roger A. Rajewski & Valentino J. Stella. (1997) Fractionation and characterization of 4-sulfobutyl ether derivatives of cyclomaltoheptaose (β-cyclodextrin). Carbohydrate Research 299:3, pages 103-110.
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Vahid Zia, Roger A. Rajewski, Esteban R. Bornancini, Ernestina A. Luna & Valentino J. Stella. (1997) Effect of Alkyl Chain Length and Degree of Substitution on the Complexation of Sulfoalkyl Ether β-Cyclodextrins with Steroids. Journal of Pharmaceutical Sciences 86:2, pages 220-224.
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Tetsumi Irie & Kaneto Uekama. (1997) Pharmaceutical Applications of Cyclodextrins. III. Toxicological Issues and Safety Evaluation. Journal of Pharmaceutical Sciences 86:2, pages 147-162.
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Roger A. Rajewski & Valentino J. Stella. (1996) Pharmaceutical Applications of Cyclodextrins. 2. In Vivo Drug Delivery. Journal of Pharmaceutical Sciences 85:11, pages 1142-1169.
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Thorsteinn Loftsson & Marcus E. Brewster. (1996) Pharmaceutical Applications of Cyclodextrins. 1. Drug Solubilization and Stabilization. Journal of Pharmaceutical Sciences 85:10, pages 1017-1025.
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E.A. Luna, E.R.N. Bornancini, R.J. Tait, D.O. Thompson, J.F. Stobaugh, R.A. Rajewski & V.J. Stella. (1996) Evaluation of the utility of capillary electrophoresis for the analysis of sulfobutyl ether β-cyclodextrin mixtures. Journal of Pharmaceutical and Biomedical Analysis 15:1, pages 63-71.
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E. A. Luna, E. R. Bornancini, D. O. Thompson, R. A. Rajewski & V. J. Stella. 1997. Proceedings of the Eighth International Symposium on Cyclodextrins. Proceedings of the Eighth International Symposium on Cyclodextrins 133 136 .
Valentino J. Stella. 1997. Proceedings of the Eighth International Symposium on Cyclodextrins. Proceedings of the Eighth International Symposium on Cyclodextrins 471 476 .
Kristiina Järvinen, Tomi Järvinen & Arto Urtti. (1995) Ocular absorption following topical delivery. Advanced Drug Delivery Reviews 16:1, pages 3-19.
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