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Current Eye Research Volume 14, 1995 - Issue 8
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Original Article

A subconjunctival degradable implant for cyclosporine delivery in corneal transplant therapy

Andrew Apel Departments of Ophthalmology, University of Toronto, Toronto, Ontario, Canada
,
Clifford Oh Departments of Ophthalmology, University of Toronto, Toronto, Ontario, Canada; Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada
,
Rosa Chiu Departments of Ophthalmology, University of Toronto, Toronto, Ontario, Canada; Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada
,
Bradley Saville Departments of Ophthalmology, University of Toronto, Toronto, Ontario, Canada; Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada
,
Yu-Ling Cheng Departments of Ophthalmology, University of Toronto, Toronto, Ontario, Canada; Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada
&
David Rootman Departments of Ophthalmology, University of Toronto, Toronto, Ontario, Canada
Pages 659-667 | Received 14 Nov 1994, Accepted 03 Apr 1995, Published online: 02 Jul 2009

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Ye Liu, Haonan Xu, Na Yan, Zhan Tang & Qiao Wang. (2023) Research progress of ophthalmic preparations of immunosuppressants. Drug Delivery 30:1.
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Hongzhuo Liu, Yongjun Wang & Sanming Li. (2007) Advanced delivery of Ciclosporin A: present state and perspective. Expert Opinion on Drug Delivery 4:4, pages 349-358.
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Articles from other publishers (16)

Tong Lin, Wushuang Wang, Ting Chen, Bingkun Bao, Tuan Liu, Han Zhao, Changming Feng, Qiuning Lin, Linyong Zhu & Lan Gong. (2023) A lacrimal duct drug delivery system based on photo-induced hydrogel for dry eye and allergic conjunctivitis therapy. Composites Part B: Engineering 266, pages 111014.
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Garima Rawat, Shital Kolhe, Dhwani Rana, Sagar Salave & Derajram Benival. (2023) Exploring the Therapeutic Potential of Cyclosporine for Ophthalmic Indications by Novel Carrier Systems. Critical Reviews™ in Therapeutic Drug Carrier Systems 40:5, pages 1-45.
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Fojan Rafiei, Hadi Tabesh & Farrokh Farzad. (2020) Sustained subconjunctival drug delivery systems: current trends and future perspectives. International Ophthalmology 40:9, pages 2385-2401.
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Dhrumi Patel & Sarika Wairkar. (2019) Recent advances in cyclosporine drug delivery: challenges and opportunities. Drug Delivery and Translational Research 9:6, pages 1067-1081.
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Mohammed Ziaei, Fatemeh Ziaei & Bita Manzouri. (2015) Systemic cyclosporine and corneal transplantation. International Ophthalmology 36:1, pages 139-146.
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Sibel Bozdağ Pehlivan, Burçin Yavuz, Semih Çalamak, Kezban Ulubayram, Abbas Kaffashi, Imran Vural, Hasan Basri Çakmak, Meltem Ezgi Durgun, Emir Baki Denkbaş & Nurşen Ünlü. (2015) Preparation and In Vitro/In Vivo Evaluation of Cyclosporin A-Loaded Nanodecorated Ocular Implants for Subconjunctival Application. Journal of Pharmaceutical Sciences 104:5, pages 1709-1720.
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A. Berna Başbağ, Menemşe Gümüşderelioğlu, Murat Şimşek & Ali Güner. (2014) Poly(HEMA)/cyclodextrin-based hydrogels for subconjunctival delivery of cyclosporin A. Journal of Applied Polymer Science 131:12, pages n/a-n/a.
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Burçin Yavuz, Sibel Bozdağ Pehlivan & Nurşen Ünlü. (2012) An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery. The Scientific World Journal 2012, pages 1-11.
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Chhavi Gupta & Anuj Chauhan. (2011) Ophthalmic delivery of cyclosporine A by punctal plugs. Journal of Controlled Release 150:1, pages 70-76.
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Susan Lee, Peng Yuan & Michael Robinson. 2008. Encyclopedia of Biomaterials and Biomedical Engineering, Second Edition - Four Volume Set. Encyclopedia of Biomaterials and Biomedical Engineering, Second Edition - Four Volume Set 1981 1995 .
ALAN L. WEINER. 2008. Ocular Therapeutics. Ocular Therapeutics 7 43 .
Alan L. Weiner & David A. Marsh. 2008. Retinal and Choroidal Angiogenesis. Retinal and Choroidal Angiogenesis 419 444 .
F. Birnbaum, A. Reis & T. Reinhard. (2007) Lokale Immunsuppressiva nach perforierender KeratoplastikTopical immunosuppressives after penetrating keratoplasty. Der Ophthalmologe 104:5, pages 381-387.
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Jagdish L. Italia, Vivekanand Bhardwaj & M.N.V. Ravi Kumar. (2006) Disease, destination, dose and delivery aspects of ciclosporin: the state of the art. Drug Discovery Today 11:17-18, pages 846-854.
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F Lallemand, O Felt-Baeyens, K Besseghir, F Behar-Cohen & R Gurny. (2003) Cyclosporine A delivery to the eye: A pharmaceutical challenge. European Journal of Pharmaceutics and Biopharmaceutics 56:3, pages 307-318.
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Lixin Xie, Weiyun Shi, Zhiyu Wang, Jianzhong Bei & Shenguo Wang. (2001) Prolongation of Corneal Allograft Survival Using Cyclosporine in a Polylactide-co-glycolide Polymer. Cornea 20:7, pages 748-752.
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