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Current Eye Research Volume 14, 1995 - Issue 1
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Original Article

Proteolysis by calpain is an underlying mechanism for formation of sugar cataract in rat lens

Mitsuyoshi Azuma Department of Oral Molecular Biology, Oregon Health Sciences University, Portland, OR, 97201, USA; Research Laboratories, Senju Pharmaceutical Co. Ltd, Kobe, Japan
,
Eri Inoue Research Laboratories, Senju Pharmaceutical Co. Ltd, Kobe, Japan
,
Takayuki Oka Research Laboratories, Senju Pharmaceutical Co. Ltd, Kobe, Japan
&
Thomas R. Shearer Department of Oral Molecular Biology, Oregon Health Sciences University, Portland, OR, 97201, USA
Pages 27-34 | Received 21 Apr 1994, Accepted 29 Sep 1994, Published online: 02 Jul 2009

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Chiho Fukiage, Mitsuyoshi Azuma, Yoshikuni Nakamura, Yoshiyuki Tamada & Thomas R. Shearer. (1998) Nuclear cataract and light scattering in cultured lenses from guinea pig and rabbit. Current Eye Research 17:6, pages 623-635.
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Articles from other publishers (19)

Lei Zhong, Tao Wang, Ting Wang, Huanhuan Cheng, Juan Deng, Hui Ye, Weihua Li & Shiqi Ling. (2021) Characterization of an i.p. D-galactose-induced cataract model in rats. Journal of Pharmacological and Toxicological Methods 107, pages 106891.
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Nobuko Akiyama, Izumi O. Umeda, Shunji Sogo, Hideo Nishigori, Masafumi Tsujimoto & Shunji Natori. (2009) 5-S-GAD, a novel radical scavenging compound, prevents lens opacity development. Free Radical Biology and Medicine 46:4, pages 511-519.
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Hannah Y. Y. Lee, James D. Morton, Julie Sanderson, Roy Bickerstaffe & Lucinda J. G. Robertson. (2008) The involvement of calpains in opacification induced by Ca 2+ -overload in ovine lens culture . Veterinary Ophthalmology 11:6, pages 347-355.
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Michael D. Aleo, Colleen M. Doshna & Kimberly A. Navetta. (2005) Ciglitazone-Induced Lenticular Opacities in Rats: In Vivo and Whole Lens Explant Culture Evaluation. Journal of Pharmacology and Experimental Therapeutics 312:3, pages 1027-1033.
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Yoji Ueda, Chiho Fukiage, Marjorie Shih, Thomas R. Shearer & Larry L. David. (2002) Mass Measurements of C-terminally Truncated α-Crystallins from Two-dimensional Gels Identify Lp82 as a Major Endopeptidase in Rat Lens. Molecular & Cellular Proteomics 1:5, pages 357-365.
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Swapan K. Ray, Denise C. Matzelle, Gloria G. Wilford, Lawrence F. Eng, Edward L. Hogan & Naren L. Banik. 2002. Role of Proteases in the Pathophysiology of Neurodegenerative Diseases. Role of Proteases in the Pathophysiology of Neurodegenerative Diseases 199 226 .
Yoshikuni Nakamura, Chiho Fukiage, Mitsuyoshi Azuma & Thomas R. Shearer. (2001) Calpain-Induced Light Scattering in Young Rat Lenses is Enhanced by UV-B. Journal of Ocular Pharmacology and Therapeutics 17:1, pages 47-58.
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Jun Inoue, Ying-She Cui, Osamu Sakai, Yoshikuni Nakamura, Hiromi Kogiso & Peter F Kador. (2000) Synthesis and aldose reductase inhibitory activities of novel N -nitromethylsulfonanilide derivatives. Bioorganic & Medicinal Chemistry 8:8, pages 2167-2173.
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Donald C. Shields, Kurt E. Schaecher, Takaomi C. Saido & Naren L. Banik. (1999) A putative mechanism of demyelination in multiple sclerosis by a proteolytic enzyme, calpain. Proceedings of the National Academy of Sciences 96:20, pages 11486-11491.
Crossref
Donald C. Shields & Naren L. Banik. (1999) Pathophysiological role of calpain in experimental demyelination. Journal of Neuroscience Research 55:5, pages 533-541.
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Reiner Eckert, Paul Donaldson, JunSheng Lin, Jacqui Bond, Colin Green, Rachelle Merriman-Smith, Mark Tunstall & Joerg Kistler. 1999. Gap Junctions - Molecular Basis of Cell Communication in Health and Disease. Gap Junctions - Molecular Basis of Cell Communication in Health and Disease 343 356 .
DONALD C SHIELDS & NAREN L BANIK. (1998) Putative Role of Calpain in the Pathophysiology of Experimental Optic Neuritis. Experimental Eye Research 67:4, pages 403-410.
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KENNETH R. HIGHTOWER & PAUL MISIAK. (1998) The Relationship between Osmotic Stress and Calcium Elevation: in vitro and in vivo Rat Lens Models. Experimental Eye Research 66:6, pages 775-781.
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Donald C Shields & Naren L Banik. (1998) Upregulation of calpain activity and expression in experimental allergic encephalomyelitis: a putative role for calpain in demyelination. Brain Research 794:1, pages 68-74.
Crossref
Colleen M.Walsh Clang & Michael D. Aleo. (1997) Mechanistic Analysis ofS-(1,2-Dichlorovinyl)-l-cysteine-Induced Cataractogenesisin Vitro. Toxicology and Applied Pharmacology 146:1, pages 144-155.
Crossref
LI-FEI WANG, PRAJAY DHIR, ARUNI BHATNAGAR & SATISH K SRIVASTAVA. (1997) Contribution of Osmotic Changes to Disintegrative Globulization of Single Cortical Fibers Isolated from Rat Lens. Experimental Eye Research 65:2, pages 267-275.
Crossref
DONALD C SHIELDS, CHRISTINE LEBLANC & NAREN L BANIK. (1997) Calcium-Mediated Neurofilament Protein Degradation in Rat Optic Nerve In Vitro: Activity and Autolysis of Calpain Proenzyme. Experimental Eye Research 65:1, pages 15-21.
Crossref
Naoki Ashizawa, Motoyuki Yoshida, Yoshiko Sugiyama, Nobuhide Akaike, Shigeo Ohbayashi, Tomoji Aotsuka, Naoki Abe, Kanako Fukushima & Akihiro Matsuura. (1997) Effects of a Novel Potent Aldose Reductase Inhibitor, GP-1447, on Aldose Reductase Activity In Vitro and on Diabetic Neuropathy and Cataract Formation in Rats. Japanese Journal of Pharmacology 73:2, pages 133-144.
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Kevin K.W. Wang & Po-wai Yuen. 1996. 117 152 .

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