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Current Eye Research Volume 15, 1996 - Issue 12
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Original Article

A primary culture model of rabbit conjunctival epithelial cells exhibiting tight barrier properties

Pratik Saha Departments of Pharmaceutical Sciences and Ophthalmology, University of Southern California, Los Angeles, CA, USA
,
Kwang-Jin Kim Departments of Pharmaceutical Sciences and Ophthalmology, University of Southern California, Los Angeles, CA, USA; Departments of Medicine, University of Southern California, Los Angeles, CA, USA; Departments of Physiology and Biophysics, University of Southern California, Los Angeles, CA, USA; Departments of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA; Departments of Will Rogers, Institute Pulmonary Research Center, University of Southern California, Los Angeles, CA, USA
&
Vincent H. L. Lee Departments of Pharmaceutical Sciences and Ophthalmology, University of Southern California, Los Angeles, CA, USA
Pages 1163-1169 | Received 07 Nov 1995, Accepted 26 Jul 1996, Published online: 02 Jul 2009

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Jaleh Barar, Ali Reza Javadzadeh & Yadollah Omidi. (2008) Ocular novel drug delivery: impacts of membranes and barriers. Expert Opinion on Drug Delivery 5:5, pages 567-581.
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Kouichi Kawazu, Hiromistu Shiono, Hidetoshi Tanioka, Atsutoshi Ota, Toshimi Ikuse, Hideo Takashina & Yoichi Kawashima. (1998) Beta adrenergic antagonist permeation across cultured rabbit corneal epithelial cells grown on permeable supports. Current Eye Research 17:2, pages 125-131.
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Jon Eidet, Darlene Dartt & Tor Utheim. (2015) Concise Review: Comparison of Culture Membranes Used for Tissue Engineered Conjunctival Epithelial Equivalents. Journal of Functional Biomaterials 6:4, pages 1064-1084.
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Deep Kwatra, Ravi Vaishya, Ripal Gaudana, Jwala Jwala & Ashim K. Mitra. 2010. Prodrugs and Targeted Delivery. Prodrugs and Targeted Delivery 181 205 .
Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky & Ashim K. Mitra. (2010) Ocular Drug Delivery. The AAPS Journal 12:3, pages 348-360.
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Nancy L. O'Sullivan, Alfred E. BaylorIIIIII & Paul C. Montgomery. (2007) Development of immortalized rat conjunctival epithelial cell lines: An in vitro model to examine transepithelial antigen delivery. Experimental Eye Research 84:2, pages 323-331.
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Margit Hornof, Elisa Toropainen & Arto Urtti. (2005) Cell culture models of the ocular barriers. European Journal of Pharmaceutics and Biopharmaceutics 60:2, pages 207-225.
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Ken-ichi Hosoya, Vincent H.L. Lee & Kwang-Jin Kim. (2005) Roles of the conjunctiva in ocular drug delivery: a review of conjunctival transport mechanisms and their regulation. European Journal of Pharmaceutics and Biopharmaceutics 60:2, pages 227-240.
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Michiko Yoshizawa, Stephen E Feinberg, Cynthia L Marcelo & Victor M Elner. (2004) Ex vivo produced human conjunctiva and oral mucosa equivalents grown in a serum-free culture system. Journal of Oral and Maxillofacial Surgery 62:8, pages 980-988.
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Ram Kannan, Hovhannes J. Gukasyan, Wenzheng Zhang, Melvin D. Trousdale, Kwang-Jin Kim & Vincent H.L. Lee. (2004) Impairment of conjunctival glutathione secretion and ion transport by oxidative stress in an adenovirus type 5 ocular infection model of pigmented rabbits. Free Radical Biology and Medicine 37:2, pages 229-238.
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M De Saint Jean, C Baudouin, M Di Nolfo, S Roman, P Lozato, J.M Warnet & F Brignole. (2004) Comparison of morphological and functional characteristics of primary-cultured human conjunctival epithelium and of Wong–Kilbourne derivative of Chang conjunctival cell line. Experimental Eye Research 78:2, pages 257-274.
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Darlene A. Dartt. (2004) Control of mucin production by ocular surface epithelial cells. Experimental Eye Research 78:2, pages 173-185.
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Gangadhar Sunkara & Uday Kompella. 2003. Ophthalmic Drug Delivery Systems, Second Edition. Ophthalmic Drug Delivery Systems, Second Edition 13 58 .
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Darlene A Dartt. (2002) Regulation of mucin and fluid secretion by conjunctival epithelial cells. Progress in Retinal and Eye Research 21:6, pages 555-576.
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Martina Scholz, Joan-En Chang Lin, Vincent H. L. Lee & Sigrid Keipert. (2002) Pilocarpine Permeability across Ocular Tissues and Cell Cultures: Influence of Formulation Parameters. Journal of Ocular Pharmacology and Therapeutics 18:5, pages 455-468.
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Vincent Lee, Jennifer Sporty, Arto Urtti & Pekka Suhonen. 2002. Cell Culture Models of Biological Barriers. Cell Culture Models of Biological Barriers 253 270 .
Michael H.I Shiue, Hovhannes J Gukasyan, Kwang-Jin Kim, Donald D.F Loo & Vincent H.L Lee. (2002) Characterization of cyclic AMP-regulated chloride conductance in the pigmented rabbit conjunctival epithelial cells. Canadian Journal of Physiology and Pharmacology 80:6, pages 533-540.
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Hovhannes J. Gukasyan, Benjamin R. Yerxa, William Pendergast & Vincent H. L. Lee. 2002. Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3. Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3 255 259 .
Helen C. Turner, Lawrence J. Alvarez & Oscar A. Candia. (2001) Identification and Localization of Acid-base Transporters in the Conjunctival Epithelium. Experimental Eye Research 72:5, pages 519-531.
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Johnny J Yang, Hideo Ueda, Kwang-Jin Kim & Vincent H.L Lee. (2000) Meeting future challenges in topical ocular drug delivery:. Journal of Controlled Release 65:1-2, pages 1-11.
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