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Review Article

Islet Amyloid Polypeptide (IAPP) A short review

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Pages 451-456 | Accepted 10 Dec 1990, Published online: 08 Jul 2009

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Richa Dubey, Shruti H. Kulkarni, Sarath Chandra Dantu, Rajlaxmi Panigrahi, Devika M. Sardesai, Nikita Malik, Jhankar D. Acharya, Jeetender Chugh, Shilpy Sharma & Ashutosh Kumar. (2021) Myricetin protects pancreatic β-cells from human islet amyloid polypeptide (hIAPP) induced cytotoxicity and restores islet function. Biological Chemistry 402:2, pages 179-194.
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C. Kokotidou, P. Tamamis & A. Mitraki. 2020. Peptide-based Biomaterials. Peptide-based Biomaterials 217 268 .
Ryu Ho Choi & Ho-Tae Kim. (2020) Analysis of oligomeric complexes of the amyloid-forming FYLLYY peptide by collision-induced dissociation with electrospray ionization mass spectrometry. European Journal of Mass Spectrometry 26:5, pages 361-368.
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Yan Sun, Chuang Guo, Lin Yuan, Wen Li, Zhan-You Wang, Feng Yue & Jia-Yi Li. (2020) Cynomolgus Monkeys With Spontaneous Type-2-Diabetes-Mellitus-Like Pathology Develop Alpha-Synuclein Alterations Reminiscent of Prodromal Parkinson’s Disease and Related Diseases. Frontiers in Neuroscience 14.
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Ammu Prasanna Kumar, Sungmun Lee & Suryani Lukman. (2019) Computational and Experimental Approaches to Design Inhibitors of Amylin Aggregation. Current Drug Targets 20:16, pages 1680-1694.
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Richa Dubey, Ketaki Patil, Sarath C. DantuDevika M. Sardesai, Parnika Bhatia, Nikita Malik, Jhankar D. Acharya, Soham Sarkar, Soumadwip Ghosh, Rajarshi Chakrabarti, Shilpy Sharma & Ashutosh Kumar. (2019) Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic β-cells from human islet amyloid polypeptide/amylin-induced cytotoxicity. Biochemical Journal 476:5, pages 889-907.
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Barbara HuisamenBarbara Huisamen. 2019. Medicinal Effects of Agathosma (Buchu) Extracts. Medicinal Effects of Agathosma (Buchu) Extracts 31 54 .
Richa Dubey, Pooja Minj, Nikita Malik, Devika M. Sardesai, Shruti H. Kulkarni, Jhankar D. Acharya, Neel Sarovar Bhavesh, Shilpy Sharma & Ashutosh Kumar. (2017) Recombinant human islet amyloid polypeptide forms shorter fibrils and mediates β-cell apoptosis via generation of oxidative stress. Biochemical Journal 474:23, pages 3915-3934.
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Pirjo L. Juusela, Rutger G. Persson, Anja R. Nieminen, Sari M. Kiuru-Enari & Veli-Jukka Uitto. (2014) Relation of gelsolin amyloidosis and periodontal health. Clinical Oral Investigations 19:2, pages 229-235.
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Lydia Young, Hlengisizwe Ndlovu, Tom W. Knapman, Sarah A. Harris, Sheena E. Radford & Alison E. Ashcroft. (2013) Monitoring oligomer formation from self-aggregating amylin peptides using ESI-IMS-MS. International Journal for Ion Mobility Spectrometry 16:1, pages 29-39.
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Nathalie M. Valette, Sheena E. Radford, Sarah A. Harris & Stuart L. Warriner. (2012) Phosphorylation as a Tool To Modulate Aggregation Propensity and To Predict Fibril Architecture. ChemBioChem 13:2, pages 271-281.
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Theri Leica Degaki, Dahabada H. J. Lopes & Mari Cleide Sogayar. 2012. Non-fibrillar Amyloidogenic Protein Assemblies - Common Cytotoxins Underlying Degenerative Diseases. Non-fibrillar Amyloidogenic Protein Assemblies - Common Cytotoxins Underlying Degenerative Diseases 217 255 .
Katsumichi Iki & Parviz M. Pour. (2006) Distribution of Pancreatic Endocrine Cells Including IAPP-expressing Cells in Non-diabetic and Type 2 Diabetic Cases. Journal of Histochemistry & Cytochemistry 55:2, pages 111-118.
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K.Y. Lam & C.Y. Lo. (1997) Pancreatic endocrine tumour: a 22-year clinico-pathological experience with morphological, immunohistochemical observation and a review of the literature. European Journal of Surgical Oncology (EJSO) 23:1, pages 36-42.
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H. Berger. (1993) Diabetes and its complications may be caused by inadequate circulation. A new concept. Medical Hypotheses 40:5, pages 259-261.
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William T. Chance, A. Balasubramaniam, A. Stallion & J.E. Fischer. (1993) Anorexia following the systemic injection of amylin. Brain Research 607:1-2, pages 185-188.
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B. H. R. WOLFFENBUTTEL & T. W. VAN HAEFTEN. (2008) Non‐insulin dependent diabetes mellitus: defects in insulin secretion. European Journal of Clinical Investigation 23:2, pages 69-79.
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C. Sternini, R. De Giorgio, K. Anderson, P. C. Watt, F. C. Brunicardi, A. L. Widdison, H. Wong, H. A. Reber, J. H. Walsh & V. L. W. Go. (1992) Species differences in the immunoreactive patterns of calcitonin gene-related peptide in the pancreas. Cell and Tissue Research 269:3, pages 447-458.
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