498
Views
40
CrossRef citations to date
0
Altmetric
Original Article

Flow Cytometric DNA Index and S-Phase Fraction in Breast Cancer in Relation to Other Prognostic Variables and to Clinical Outcome

, , , , &
Pages 157-165 | Received 24 Jul 1991, Accepted 20 Sep 1991, Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Mårten Fernö, Christina Andersson, Ghita Fallenius & Ingrid Idvall. (1996) Oestrogen Receptor Analysis of Paraffin Sections and Cytosol Samples of Primary Breast Cancer in Relation to Outcome After Adjuvant Tamoxifen Treatment. Acta Oncologica 35:1, pages 17-22.
Read now
Yrjö U. Collan, Matti J. Eskelinen, Stig A. Nordling, Pertti Lipponen, Erkki Pesonen, Leena M. Kumpusalo, Pfkka Pajarinen & Kauko O. Kettunen. (1994) Prognostic Studies in Breast Cancer: Multivariate combination of nodal status, proliferation index, tumor size, and DNA ploidy. Acta Oncologica 33:8, pages 873-878.
Read now
Olle Stal, John M. Carstensen, Sten Wingren, Lars Erik Rutqvist, Lambert Skoog, Claes Klintenberg & Bo Nordenskjold. (1994) Relationship of DNA Ploidy and S-Phase Fraction to Survival After First Recurrence of Breast Cancer. Acta Oncologica 33:4, pages 423-429.
Read now

Articles from other publishers (37)

Geetanjali Saini, Shriya Joshi, Chakravarthy Garlapati, Hongxiao Li, Jun Kong, Jayashree Krishnamurthy, Michelle D. Reid & Ritu Aneja. (2022) Polyploid giant cancer cell characterization: New frontiers in predicting response to chemotherapy in breast cancer. Seminars in Cancer Biology 81, pages 220-231.
Crossref
J H S Dayal, M J Sales, W E Corver, C A Purdie, L B Jordan, P R Quinlan, L Baker, N T ter Haar, N R Pratt & A M Thompson. (2013) Multiparameter DNA content analysis identifies distinct groups in primary breast cancer. British Journal of Cancer 108:4, pages 873-880.
Crossref
Joško Bezić, Ivana Šamija-Projić, Petar Projić, Jelena Ljubković, Sandra Tomaš-Zekić, Maja Marinović-Guić & Snježana Tomić. (2012) Near-Diploid Hyperploidy in Early Breast Cancer (T1a,b) is Associated with Higher Risk of Lymph Node Involvement. Pathology & Oncology Research 19:1, pages 71-77.
Crossref
A Elzagheid, T Kuopio, S Pyrhönen & Y Collan. (2006) Lymph node status as a guide to selection of available prognostic markers in breast cancer: the clinical practice of the future?. Diagnostic Pathology 1:1.
Crossref
M. Colozza, E. Azambuja, F. Cardoso, C. Sotiriou, D. Larsimont & M.J. Piccart. (2005) Proliferative markers as prognostic and predictive tools in early breast cancer: where are we now?. Annals of Oncology 16:11, pages 1723-1739.
Crossref
Jean-Jacques Michels, Jacques Marnay, Beno�t Plancoulaine & Jacques Chasle. (2004) Flow cytometry in primary breast carcinomas: Prognostic impact of S-phase fraction according to different analysis patterns. Cytometry 59B:1, pages 32-39.
Crossref
Jean‐Jacques Michels, Jacques Marnay, Thierry Delozier, Yves Denoux & Jacques Chasle. (2004) Proliferative activity in primary breast carcinomas is a salient prognostic factor. Cancer 100:3, pages 455-464.
Crossref
Bo Baldetorp, Pär-Ola Bendahl, Mårten Fernö & Olle Stål. (2003) Improved DNA flow cytometric, DNA ploidy, and S-phase reproducibility between 15 laboratories in analysis of breast cancer using generalized guidelines. Cytometry Part A 56A:1, pages 1-7.
Crossref
Jean-Jacques Michels, Fran�oise Duigou, Jacques Marnay, Yves Denoux, Thierry Delozier & Jacques Chasle. (2003) Flow cytometry in primary breast carcinomas: Prognostic impact of multiploidy and hypoploidy. Cytometry 55B:1, pages 37-45.
Crossref
Rubin Wang, Jenny C Titley, Yong-Jie Lu, Brenda M Summersgill, Julia A Bridge, Cyril Fisher & Janet Shipley. (2003) Loss of 13q14-q21 and Gain of 5p14-pter in the Progression of Leiomyosarcoma. Modern Pathology 16:8, pages 778-785.
Crossref
Jean‐Jacques Michels, Françoise Duigou, Jacques Marnay, Michel Henry‐Amar, Thierry Delozier, Yves Denoux & Jacques Chasle. (2003) Flow cytometry and quantitative immunohistochemical study of cell cycle regulation proteins in invasive breast carcinoma. Cancer 97:6, pages 1376-1386.
Crossref
C.B. Bagwell, G.M. Clark, F. Spyratos, A. Chassevent, P.-O. Bendahl, O. Stål, D. Killander, M.L. Jourdan, S. Romain, B. Hunsberger & B. Baldetorp. (2001) Optimizing flow cytometric DNA ploidy and S-phase fraction as independent prognostic markers for node-negative breast cancer specimens. Cytometry 46:3, pages 121-135.
Crossref
Stefania Staibano, Lorenzo Lo Muzio, Giuseppe Pannone, Ernesto Mezza, Giuseppe Argenziano, Antonio Vetrani, Antonio Lucariello, Renato Franco, Maria E. Errico & Gaetano De Rosa. (2001) DNA Ploidy and Cyclin D1 Expression in Basal Cell Carcinoma of the Head and Neck. American Journal of Clinical Pathology 115:6, pages 805-813.
Crossref
Marie Sundquist, Sten Thorstenson, Lars Brudin, Olle Stål & Bo Nordenskjöld. (2000) A comparison between flow cytometric assessment of S-phase fraction and Nottingham histologic grade as prognostic instruments in breast cancer. Breast Cancer Research and Treatment 63:1, pages 11-15.
Crossref
Jean-Jacques Michels, Françoise Duigou & Jacques Marnay. (2000) Flow cytometry in primary breast carcinomas. Prognostic impact of proliferative activity. Breast Cancer Research and Treatment 62:2, pages 117-126.
Crossref
William H. Goodson, Dan H. Moore, Britt-Marie Ljung, Karen Chew, Brian Mayall, Helene S. Smith & Frederic M. Waldman. (2000) The prognostic value of proliferation indices: a study with in vivo bromodeoxyuridine and Ki-67. Breast Cancer Research and Treatment 59:2, pages 113-123.
Crossref
Adel K. El-Naggar, Mai Dinh, Susan L. Tucker, David Swanson, Kim Steck & Philippe Vielh. (1999) Numerical chromosomal changes in DNA hypodiploid solid tumors: Restricted loss and gain of certain chromosomes. Cytometry 37:2, pages 107-112.
Crossref
Karin Persson, Nikos Pandis, Fredrik Mertens, �ke Borg, Bo Baldetorp, Dick Killander & Jorma Isola. (1999) Chromosomal aberrations in breast cancer: A comparison between cytogenetics and comparative genomic hybridization. Genes, Chromosomes and Cancer 25:2, pages 115-122.
Crossref
Minna M. Tanner, Ritva A. Karhu, Nina N. Nupponen, Åke Borg, Bo Baldetorp, Tanja Pejovic, Mårten Fernö, Dick Killander & Jorma J. Isola. (1998) Genetic Aberrations in Hypodiploid Breast Cancer. The American Journal of Pathology 153:1, pages 191-199.
Crossref
Maria T. del Vecchio, Stefano Lazzi, Alessandra Bruni, Paola Mangiavacchi, Gabriele Cevenini & Pietro Luzi. (1998) DNA ploidy pattern in papillary renal cell carcinoma. Correlation with clinicopathological parameters and survival. Pathology - Research and Practice 194:5, pages 325-333.
Crossref
LISE PEDERSEN. (2011) Medullary Carcinoma of the Breast. APMIS 105:S75, pages 5-31.
Crossref
. 1997. The Genetics of Cancer. The Genetics of Cancer 215 326 .
Kelly K. Hunt & Merrick I. Ross. 1997. Surgical Oncology. Surgical Oncology 171 201 .
T. Lynn Eudey. (1996) Statistical considerations in DNA flow cytometry. Statistical Science 11:4.
Crossref
M. Fernö, P.-O. Bendahl, Å. Borg, J. Brundell, L. Hirschberg, H. Olsson & D. Killander. (1996) Urokinase plasminogen activator, a strong independent prognostic factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay. European Journal of Cancer 32:5, pages 793-801.
Crossref
G. COSTA, G. LASCARI, M. ARAGONA, G. FERLAZZO, V. ADAMO, R. GANGEMI, O. GERACI, G. PASTURA, M. MESITI & L. CASTAGNETTA. (1996) Biological Parameters in Breast Cancer. Annals of the New York Academy of Sciences 784:1 Challenges an, pages 521-524.
Crossref
I. D'AGNANO, B. BUCCI, M. MOTTOLESE, M. BENEVOLO, L. CONTI, C. BOTTI, A. VECCHIONE, S. CASILLO & G. ZUPI. (1996) DNA Ploidy, Cell Kinetics, and Epidermal Growth Factor Receptor and HER2/neu Oncoprotein Expression in Primary Operable Breast Cancer. Annals of the New York Academy of Sciences 784:1 Challenges an, pages 472-481.
Crossref
Stanley E. Shackney, Sarita G. Singh, Robert Yakulis, Charles A. Smith, Agnese A. Pollice, Susan Petruolo, Alan Waggoner & Robert J. Hartsock. (2005) Aneuploidy in breast cancer: A fluorescence in situ hybridization study. Cytometry 22:4, pages 282-291.
Crossref
Bo Baldetorp, Pär‐Ola Bendahl, Mårten Fernö, Kalle Alanen, Ulla Delle, Ursula Falkmer, Britt Hansson‐Aggesjö, Thomas Höckenström, Anders Lindgren, Lotta Mossberg, Stig Nordling, Helgi Sigurdsson, Olle Stål & Tapio Visakorpi. (2005) Reproducibility in DNA flow cytometric analysis of breast cancer: Comparison of 12 laboratories' results for 67 sample homogenates. Cytometry 22:2, pages 115-127.
Crossref
M.D Péreze Alenza, G.R Rutteman, N.J Kuipers-Dijkshoorn, L Peña, A Montoya, W Misdorp & C.J Cornelisse. (1995) dna flow cytometry of canine mammary tumours: the relationship of dna ploidy and S-phase fraction to clinical and histological features. Research in Veterinary Science 58:3, pages 238-243.
Crossref
Sigurlaug Skirnisdottir, Gudny Eiriksdottir, Trausti Baldursson, Rosa B. Barkardottir, Valgardur Egilsson & Sigurdur Ingvarsson. (2006) High frequency of allelic imbalance at chromosome region 16q22‐23 in human breast cancer: Correlation with high pgr and low s phase. International Journal of Cancer 64:2, pages 112-116.
Crossref
Yorghos Remvikos, Henri Magdelenat & Bernard Dutrillaux. (1995) Genetic evolution of breast cancers III: Age-dependent variations in the correlations between biological indicators of prognosis. Breast Cancer Research and Treatment 34:1, pages 25-33.
Crossref
M. Gion, R. Mione, A. Becciolini, M. Balzi, M. Correale, A. Piffanelli, G. Giovannini, G. Saccani Jotti & M. Fontanesi. (2018) Relationship between Cytosol Tps, Tpa and Cell Proliferation. The International Journal of Biological Markers 9:2, pages 109-114.
Crossref
Ingegerd Balslev, Ib J. Christensen, Birgitte Bruun Rasmussen, Jørgen K. Larsen, Anne E. Lykkesfeldt, Susan M. Thorpe, Carsten Rose, Per Briand & Henning T. Mouridsen. (2007) Flow cytometric DNA ploidy defines patients with poor prognosis in node‐negative breast cancer. International Journal of Cancer 56:1, pages 16-25.
Crossref
Edward G. Mansour, Peter M. Ravdin & Lynn Dressier. (1994) Prognostic factors in early breast carcinoma. Cancer 74:S1, pages 381-400.
Crossref
David W. Hedley, Gary M. Clark, Cees J. Cornelisse, Dick Killander, Timothy Kute & Douglas Merkel. (1993) Consensus review of the clinical utility of DNA cytometry in carcinoma of the breast. Breast Cancer Research and Treatment 28:1, pages 55-59.
Crossref
David W. Hedley, Gary M. Clark, Cees J. Cornelisse, Dick Killander, Timothy Kute & Douglas Merkel. (1993) Consensus review of the clinical utility of dna cytometry in carcinoma of the breast. Cytometry 14:5, pages 482-485.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.