741
Views
77
CrossRef citations to date
0
Altmetric
Original Article

On Radiation Damage to Normal Tissues and its Treatment: II. Anti-inflammatory drugs

Pages 139-157 | Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Pavan Gollapalli, Avinash Karkada Ashok & Tamizh Selvan G. (2023) System-level protein interaction network analysis and molecular dynamics study reveal interaction of ferulic acid with PTGS2 as a natural radioprotector. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-17.
Read now
Stephanie Puukila, Stacy Muise, James McEvoy, Tara Bouchier, Antony M. Hooker, Douglas R. Boreham, Neelam Khaper & Dani-Louise Dixon. (2019) Acute pulmonary and splenic response in an in vivo model of whole-body low-dose X-radiation exposure. International Journal of Radiation Biology 95:8, pages 1072-1084.
Read now
María del Mar Roca-Rodríguez, Jose Manuel García-Almeida, Josefina Ruiz-Nava, Juan Alcaide, Yolanda Lupiañez-Pérez, Jose Manuel Rico-Pérez, María Dolores Toledo-Serrano, Fernando Cardona, Jose Antonio Medina-Carmona & Francisco J. Tinahones. (2015) Long-term effects of varying consumption of ω3 fatty acids in ear, nose and throat cancer patients: assessment 1 year after radiotherapy. International Journal of Food Sciences and Nutrition 66:1, pages 108-113.
Read now
Jacqueline P. Williams & William H. McBride. (2011) After the bomb drops: A new look at radiation-induced multiple organ dysfunction syndrome (MODS). International Journal of Radiation Biology 87:8, pages 851-868.
Read now
M. E. C. Robbins & W. Zhao. (2004) Chronic oxidative stress and radiation‐induced late normal tissue injury: a review. International Journal of Radiation Biology 80:4, pages 251-259.
Read now
M. W. Gaber, O. M. Sabek, K. Fukatsu, H. G. Wilcox, M. F. Kiani & T. E. Merchant. (2003) Differences in ICAM‐1 and TNF‐α expression between large single fraction and fractionated irradiation in mouse brain. International Journal of Radiation Biology 79:5, pages 359-366.
Read now
Athanasia Damatopoulou, Basil Agroyannis, Constantinos Dardoufas, Androniki Dalamangas, Dimitris Koutsikos & Labros Vlachos. (1996) Changes Acute Phase Proteins by Radiation Treatment. Acta Oncologica 35:6, pages 766-766.
Read now
Adam S. Michalowski. (1995) Is Coronary Artery Disease Associated with Radiotherapy Preventable by Salicylates?. Acta Oncologica 34:1, pages 126-126.
Read now

Articles from other publishers (68)

Rajwinder Kaur, Damanpreet Kaur Lang, Harwinder Singh, Arpita Arora, Nikhil Garg & Balraj Saini. (2023) Repurposing of Various Current Medicines as Radioprotective Agents. Anti-Cancer Agents in Medicinal Chemistry 23:10, pages 1104-1121.
Crossref
Usman Beg, Brianna Michelle Snyder, Sarosh Irfan Madhani, Nima Hamidi, Varun Padmanaban, Leonard C. Tuanquin, Timothy J. Kruser, James Connor & Alireza Mansouri. (2021) Current Landscape and Future Prospects of Radiation Sensitizers for Malignant Brain Tumors: A Systematic Review. World Neurosurgery 151, pages e839-e856.
Crossref
Keith Unger, Yaoxiang Li, Celine Yeh, Ana Barac, Monvadi B Srichai, Elizabeth A Ballew, Michael Girgis, Meth Jayatilake, Vijayalakshmi Sridharan, Marjan Boerma & Amrita K Cheema. (2020) Plasma metabolite biomarkers predictive of radiation induced cardiotoxicity. Radiotherapy and Oncology 152, pages 133-145.
Crossref
F. Fekrmandi, T. Panzarella, R. E. Dinniwell, J. Helou & W. Levin. (2019) Predictive factors for persistent and late radiation complications in breast cancer survivors. Clinical and Translational Oncology 22:3, pages 360-369.
Crossref
Branislav Kura, Barbora Kalocayova, Yvan Devaux & Monika Bartekova. (2020) Potential Clinical Implications of miR-1 and miR-21 in Heart Disease and Cardioprotection. International Journal of Molecular Sciences 21:3, pages 700.
Crossref
Ibrahim Abdelgawad, Marianne Grant & Beshay Zordoky. (2019) Leveraging the Cardio-Protective and Anticancer Properties of Resveratrol in Cardio-Oncology. Nutrients 11:3, pages 627.
Crossref
Rowaida Refaat, Dalia Sarhan, Metwali Kotb, Eman El-Abd & Emad El-Bassiouni. (2018) Post-irradiation protective effects of ectoine on brain and testicles in male mice. Pharmacological Reports 70:2, pages 304-308.
Crossref
Branislav KuraPavel BabalJan Slezak. (2017) Implication of microRNAs in the development and potential treatment of radiation-induced heart disease. Canadian Journal of Physiology and Pharmacology 95:10, pages 1236-1244.
Crossref
Omaima Mohamed Ashry & Hesham Farouk Hasan. (2017) The Evolving Role of Erythropoietin in Lung of Irradiated Rats. Brazilian Archives of Biology and Technology 60:0.
Crossref
Terence Verla, Jonathan G. Thomas, Vilmos ThomazyGregory N. Fuller, Aziz Shaibani & Ibrahim Omeis. (2016) Fulminant spinal cord compression caused by postradiation inflammatory pseudotumor with rapid response to steroids: case report. Journal of Neurosurgery: Spine 25:5, pages 660-664.
Crossref
Soile Tapio. (2016) Pathology and biology of radiation-induced cardiac disease. Journal of Radiation Research 57:5, pages 439-448.
Crossref
Markus Laube, Torsten Kniess & Jens Pietzsch. (2016) Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy—A Hypothesis-Driven Review. Antioxidants 5:2, pages 14.
Crossref
François-Xavier Boittin, Josiane Denis, Jean-François Mayol, Patrick Martigne, Florent Raffin, David Coulon, Nancy Grenier, Michel Drouet & Francis Hérodin. (2015) The Extent of Irradiation-Induced Long-Term Visceral Organ Damage Depends on Cranial/Brain Exposure. PLOS ONE 10:4, pages e0122900.
Crossref
Michaela Kreuzer, Anssi Auvinen, Elisabeth Cardis, Janet Hall, Jean-Rene Jourdain, Dominique Laurier, Mark P. Little, Annette Peters, Ken Raj, Nicola S. Russell, Soile Tapio, Wei Zhang & Maria Gomolka. (2015) Low-dose ionising radiation and cardiovascular diseases – Strategies for molecular epidemiological studies in Europe. Mutation Research/Reviews in Mutation Research 764, pages 90-100.
Crossref
M.M. Anwar & N.E. Mohamed. (2015) Amelioration of liver and kidney functions disorders induced by sodium nitrate in rats using wheat germ oil. Journal of Radiation Research and Applied Sciences 8:1, pages 77-83.
Crossref
M.M. ROCA-RODRÍGUEZ, J.M. GARCÍA-ALMEIDA, Y. LUPIAÑEZ-PÉREZ, J.M. RICO, M. TOLEDO, J. ALCAIDE-TORRES, F. CARDONA, J.A. MEDINA & F.J. TINAHONES. (2014) Effect of a specific supplement enriched with n-3 polyunsaturated fatty acids on markers of inflammation, oxidative stress and metabolic status of ear, nose and throat cancer patients. Oncology Reports 31:1, pages 405-414.
Crossref
C.B. Westbury & J.R. Yarnold. (2012) Radiation Fibrosis — Current Clinical and Therapeutic Perspectives. Clinical Oncology 24:10, pages 657-672.
Crossref
Michal Hofer, Milan Pospíšil, Zuzana Hoferová, Lenka Weiterová & Denisa Komůrková. (2012) Stimulatory Action of Cyclooxygenase Inhibitors on Hematopoiesis: A Review. Molecules 17:5, pages 5615-5625.
Crossref
Arundhathi Sriharshan, Karsten Boldt, Hakan Sarioglu, Zarko Barjaktarovic, Omid Azimzadeh, Ludwig Hieber, Horst Zitzelsberger, Marius Ueffing, Michael J. Atkinson & Soile Tapio. (2012) Proteomic analysis by SILAC and 2D-DIGE reveals radiation-induced endothelial response: Four key pathways. Journal of Proteomics 75:8, pages 2319-2330.
Crossref
F.A. Stewart, A.V. Akleyev, M. Hauer-Jensen, J.H. Hendry, N.J. Kleiman, T.J. MacVittie, B.M. Aleman, A.B. Edgar, K. Mabuchi, C.R. Muirhead, R.E. Shore & W.H. Wallace. (2012) ICRP PUBLICATION 118: ICRP Statement on Tissue Reactions and Early and Late Effects of Radiation in Normal Tissues and Organs — Threshold Doses for Tissue Reactions in a Radiation Protection Context. Annals of the ICRP 41:1-2, pages 1-322.
Crossref
Archana P.R, B. Nageshwar Rao & B.S. Satish Rao. (2011) In vivo radioprotective potential of thymol, a monoterpene phenol derivative of cymene. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 726:2, pages 136-145.
Crossref
C. Bourgier, V. Monceau, J. Bourhis, É. Deutsch & M.-C. Vozenin. (2011) Modulation pharmacologique des effets tardifs de l’irradiation. Cancer/Radiothérapie 15:5, pages 383-389.
Crossref
A. Wittig & R. Engenhart-Cabillic. (2011) Cardiac side effects of conventional and particle radiotherapy in cancer patientsKardiale Nebenwirkungen der konventionellen und Partikel- Strahlentherapie bei Tumorpatienten. Herz 36:4, pages 311-324.
Crossref
Ritsuko Komaki, Zhongxing Liao, James D. Cox, Kathy A. Mason & Luka Milas. 2011. Advances in Radiation Oncology in Lung Cancer. Advances in Radiation Oncology in Lung Cancer 223 245 .
F. A. Stewart, S. Hoving & N. S. Russell. (2010) Vascular Damage as an Underlying Mechanism of Cardiac and Cerebral Toxicity in Irradiated Cancer Patients. Radiation Research 174:6b, pages 865-869.
Crossref
Ming-Yii Huang, Joh-Jong Huang, Chee-Yin Chai, Shih-Hsien Chen, Ming-Ping Kuo & Ching-Cheng Lin. (2010) The Reduction Effect of Extracts of Soybean Seeds on Acute Radiation Dermatitis. Fooyin Journal of Health Sciences 2:1, pages 21-25.
Crossref
Henri A. Vuilleumier & Abderrahim Zouhair. 2010. Anorectal and Colonic Diseases. Anorectal and Colonic Diseases 769 782 .
M. T. Khayyal, Mona A. El-Ghazaly, R. M. El-Hazek & A. S. Nada. (2009) The effects of celecoxib, a COX-2 selective inhibitor, on acute inflammation induced in irradiated rats. Inflammopharmacology 17:5, pages 255-266.
Crossref
S. K. Mantena, M. K. Unnikrishnan & P. Uma Devi. (2008) Radioprotective effect of sulfasalazine on mouse bone marrow chromosomes. Mutagenesis 23:4, pages 285-292.
Crossref
S.K. Mantena, M.K. Unnikrishnan, Ravi Joshi, V. Radha, P. Uma Devi & T. Mukherjee. (2008) In vivo radioprotection by 5-aminosalicylic acid. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 650:1, pages 63-79.
Crossref
Michael G. Franz, David L. Steed & Martin C. Robson. (2007) Optimizing Healing of the Acute Wound by Minimizing Complications. Current Problems in Surgery 44:11, pages 691-763.
Crossref
Yildiz Guney, Ummuhani Ozel Turkcu, Ayse Hicsonmez, Meltem Nalca Andrieu & Cengiz Kurtman. (2007) Ghrelin may reduce radiation-induced mucositis and anorexia in head-neck cancer. Medical Hypotheses 68:3, pages 538-540.
Crossref
M.E.C. Robbins & W. Zhao. 2007. Oxidative Stress and Neurodegenerative Disorders. Oxidative Stress and Neurodegenerative Disorders 135 164 .
Michal Hofer & Milan Pospíšil. (2006) Stimulated recovery of perturbed haematopoiesis by inhibition of prostaglandin production — promising therapeutic strategy. Open Life Sciences 1:4, pages 584-593.
Crossref
Diclehan Unsal, Bulent Mentes, Muge Akmansu, Aytug Uner, Mehmet Oguz & Yucel Pak. (2006) Evaluation of Nutritional Status in Cancer Patients Receiving Radiotherapy. American Journal of Clinical Oncology 29:2, pages 183-188.
Crossref
Mukut Sharma, Ellen T. McCarthy, Ram Sharma, Brian L. Fish, Virginia J. Savin, Eric P. Cohen & John E. Moulder. (2016) Arachidonic Acid Metabolites Mediate the Radiation-Induced Increase in Glomerular Albumin Permeability. Experimental Biology and Medicine 231:1, pages 99-106.
Crossref
Kristin Bradley & H. Ian Robins. 2006. Oncology. Oncology 1427 1434 .
Wendy Maddocks-Jennings, Jenny M Wilkinson & David Shillington. (2005) Novel approaches to radiotherapy-induced skin reactions: A literature review. Complementary Therapies in Clinical Practice 11:4, pages 224-231.
Crossref
Gijsbert W.P.M. Kramer, Stofferinus L. Wanders, Ed M. Noordijk, Ernest J.A. Vonk, Hans C. van Houwelingen, Wilbert B. van den Hout, Ronald B. Geskus, Mirjam Scholten & Jan-Willem H. Leer. (2005) Results of the Dutch National Study of the Palliative Effect of Irradiation Using Two Different Treatment Schemes for Non–Small-Cell Lung Cancer. Journal of Clinical Oncology 23:13, pages 2962-2970.
Crossref
Leandro C. A. Cerchietti, Marcelo R. Bonomi, Alfredo H. Navigante, Monica A. Castro, Maria E. Cabalar & Berta M. C. Roth. (2005) Phase I/II study of selective cyclooxygenase-2 inhibitor celecoxib as a radiation sensitizer in patients with unresectable brain metastases. Journal of Neuro-Oncology 71:1, pages 73-81.
Crossref
Scott W. Cousins, Karl G. Csaky & Diego G. Espinosa-Heidmann. 2005. Macular Degeneration. Macular Degeneration 167 200 .
Ritsuko Komaki, Joe Chang, Zhongxing Liao, James D. Cox, K. A. Mason & Luka Milas. 2005. Advances in Radiation Oncology in Lung Cancer. Advances in Radiation Oncology in Lung Cancer 123 134 .
Sylvie Delanian & Jean-Louis Lefaix. (2004) The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. Radiotherapy and Oncology 73:2, pages 119-131.
Crossref
John E. Moulder. (2003) Pharmacological intervention to prevent or ameliorate chronic radiation injuries. Seminars in Radiation Oncology 13:1, pages 73-84.
Crossref
Felicia A. Mendelsohn, Celia M. Divino, Ernane D. Reis & Morris D. Kerstein. (2002) Wound Care After Radiation Therapy. Advances in Skin & Wound Care 15:5, pages 216-224.
Crossref
Stephanos Kyrkanides, Amy H Moore, John A Olschowka, JoAnna C Daeschner, Jacqueline P Williams, John T Hansen & M Kerry O’Banion. (2002) Cyclooxygenase-2 modulates brain inflammation-related gene expression in central nervous system radiation injury. Molecular Brain Research 104:2, pages 159-169.
Crossref
Peter E. Lonergan, Darren S.D. Martin, David F. Horrobin & Marina A. Lynch. (2002) Neuroprotective Effect of Eicosapentaenoic Acid in Hippocampus of Rats Exposed to γ-Irradiation. Journal of Biological Chemistry 277:23, pages 20804-20811.
Crossref
E. D. Reis, A. J. Vine & T. Heimann. (2002) Radiation damage to the rectum and anus: pathophysiology, clinical features and surgical implications. Colorectal Disease 4:1, pages 2-12.
Crossref
Diclehan Kilic, Seren Ozenirler, Ibrahim Egehan & Ayse Dursun. (2016) Sulfasalazine Decreases Acute Gastrointestinal Complications Due to Pelvic Radiotherapy. Annals of Pharmacotherapy 35:7-8, pages 806-810.
Crossref
Anne Van der Meeren, Pascale Monti, Laurence Lebaron-Jacobs, Christel Marquette & Patrick Gourmelon. (2001) Characterization of the Acute Inflammatory Response after Irradiation in Mice and its Regulation by Interleukin 4 (Il4). Radiation Research 155:6, pages 858-865.
Crossref
Diclehan Kiliç, İbrahim Egehan, Seren Özenirler & Ayşe Dursun. (2000) Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of sulphasalazine in preventing acute gastrointestinal complications due to radiotherapy. Radiotherapy and Oncology 57:2, pages 125-129.
Crossref
Kirsten K Steinauer, Iris Gibbs, Shoucheng Ning, John N French, Jeff Armstrong & Susan J Knox. (2000) Radiation induces upregulation of cyclooxygenase-2 (COX-2) protein in PC-3 cells. International Journal of Radiation Oncology*Biology*Physics 48:2, pages 325-328.
Crossref
D. Kilic & H. Sayan. (2000) The effect of granulocyte macrophage-colony stimulating factor on the prostaglandin E2-like activity of the small intestine of rat during total body irradiation. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 62:6, pages 349-353.
Crossref
Anne Van Der Meeren, Claire Squiban, Patrick Gourmelon, Hélène Lafont & Marie-Hélène Gaugler. (1999) DIFFERENTIAL REGULATION BY IL-4 AND IL-10 OF RADIATION-INDUCED IL-6 AND IL-8 PRODUCTION AND ICAM-1 EXPRESSION BY HUMAN ENDOTHELIAL CELLS. Cytokine 11:11, pages 831-838.
Crossref
Dietrich E Lorke, Sören Wenzel, Klaus Siebert & Friedrich Zywietz. (1999) Microvascular and tumor cell alterations during continuous hyperfractionated irradiation: an electron microscopic investigation on the rat R1H rhabdomyosarcoma. International Journal of Radiation Oncology*Biology*Physics 44:4, pages 895-904.
Crossref
M. Pospíšil. 1999. Fundamentals for the Assessment of Risks from Environmental Radiation. Fundamentals for the Assessment of Risks from Environmental Radiation 411 420 .
Paivi Simonen, Chris Hamilton, Sandra Ferguson, Patricia Ostwald, Maree O'Brien, Peter O'Brien, Michael Back & Jim Denham. (1998) Do inflammatory processes contribute to radiation induced erythema observed in the skin of humans?. Radiotherapy and Oncology 46:1, pages 73-82.
Crossref
H. A. Vuilleumier & E. D. Reis. 1998. Surgical Management of Anorectal and Colonic Diseases. Surgical Management of Anorectal and Colonic Diseases 423 435 .
John E. Moulder, Michael E. C. Robbins, Eric P. Cohen, John W. Hopewell & William F. Ward. 1998. Advances in Radiation Therapy. Advances in Radiation Therapy 129 151 .
W. Dörr. (1997) Ansätze zur konservativen Behandlung von StrahlenfolgenConservative treatment of radiotherapy sequelae. Strahlentherapie und Onkologie 173:9, pages 480-483.
Crossref
Adam S. Michalowski. (1997) Treatment of radiation-induced enterocolitis. International Journal of Radiation Oncology*Biology*Physics 38:4, pages 908-909.
Crossref
Matthew Q.F. Hatton, Desni L. Nixon, Fergus R. MacBeth & R.Paul Symonds. (1997) Acute changes in peak expiratory flow rate following palliative radiotherapy for bronchial carcinoma. Radiotherapy and Oncology 44:1, pages 31-34.
Crossref
Ryuji Murakami, Yuji Baba, Ryuichi Nishimura, Mitsuhiro Furusawa, Toshimi Yokoyama, Yasuyuki Yamashita, Mutsumasa Takahashi, Naoko Yamashita & Tomomichi Ono. (1997) The effect of azelastine on acute radiation dermatitis in mice models. International Journal of Radiation Oncology*Biology*Physics 37:4, pages 907-911.
Crossref
C. Ts'ao, W.F. Ward, A. Molteni, J.M. Taylor & F.H.C. Tsao. (1997) Annexin I concentration and prostacyclin production in rat lung and alveolar macrophages following irradiation. Prostaglandins, Leukotrienes and Essential Fatty Acids 56:2, pages 99-104.
Crossref
B. Maciejewski. (1997) Is acute mucositis a dose limiting factor in altered fractionated radiotherapy?. Reports of Practical Oncology 2:3, pages 65-69.
Crossref
S. Devereux, M.Q.F. Hatton & F.R. Macbeth. (1997) Immediate side effects of large fraction radiotherapy. Clinical Oncology 9:2, pages 96-99.
Crossref
Adam S. Michalowski. (1996) Regarding Martenson et al, IJROBP 35:299–303; 1996. International Journal of Radiation Oncology*Biology*Physics 36:5, pages 1285-1286.
Crossref
L. Milas & W.R. Hanson. (1995) Eicosanoids and radiation. European Journal of Cancer 31:10, pages 1580-1585.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.