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Original Articles

Metformin use and improved response to therapy in esophageal adenocarcinoma

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Pages 1002-1009 | Received 15 Jun 2012, Accepted 28 Jul 2012, Published online: 05 Sep 2012

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Rodrigo Oliva Perez, Laura M. Fernandez & Cinthia D. Ortega. (2020) Metformin Use in Patients With Rectal Cancer Undergoing Neoadjuvant Chemoradiation: The New Magic Bullet?. Diseases of the Colon & Rectum 63:6, pages 718-719.
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Michael Pawlak & Neil O. Carragher. (2017) Reverse Phase Protein Arrays elucidate mechanisms-of-action and phenotypic response in 2D and 3D models. Drug Discovery Today: Technologies 23, pages 7-16.
Crossref
L. Raffaghello & V. Longo. 2017. 1 42 .
Xiaofeng Qi, Wengguang Xu, Junqi Xie, Yufeng Wang, Shengwei Han, Zheng Wei, Yanhong Ni, Yingchun Dong & Wei Han. (2016) Metformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis. Scientific Reports 6:1.
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Sanjana Chowdhury, Eric Yung, Melania Pintilie, Hala Muaddi, Selim Chaib, ManTek Yeung, Manlio Fusciello, Jenna Sykes, Bethany Pitcher, Anna Hagenkort, Trevor McKee, Ravi Vellanki, Eric Chen, Robert G. Bristow, Bradly G. Wouters & Marianne Koritzinsky. (2016) MATE2 Expression Is Associated with Cancer Cell Response to Metformin. PLOS ONE 11:12, pages e0165214.
Crossref
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Crossref
Zachery R. Reichert, Daniel R. Wahl & Meredith A. Morgan. (2016) Translation of Targeted Radiation Sensitizers into Clinical Trials. Seminars in Radiation Oncology 26:4, pages 261-270.
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Vera Hirsh, Amy Ko, Richard Pilot, Markus F. Renschler & Mark A. Socinski. (2016) Weekly nab-Paclitaxel in Combination With Carboplatin as First-Line Therapy in Patients With Advanced Non?Small-Cell Lung Cancer: Analysis of Safety and Efficacy in Patients With Diabetes. Clinical Lung Cancer 17:5, pages 367-374.
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Crossref
Scott J Warchal, Asier Unciti-Broceta & Neil O Carragher. (2016) Next-generation phenotypic screening. Future Medicinal Chemistry 8:11, pages 1331-1347.
Crossref
Bo Young Oh, Yoon Ah Park, Jung Wook Huh, Yong Beom Cho, Seong Hyeon Yun, Woo Yong Lee, Hee Chul Park, Doo Ho Choi, Young Suk Park & Hee Cheol Kim. (2016) Metformin enhances the response to radiotherapy in diabetic patients with rectal cancer. Journal of Cancer Research and Clinical Oncology 142:6, pages 1377-1385.
Crossref
Zhigui Guo, Manqing Cao, Abin You, Junrong Gao, Hongyuan Zhou, Huikai Li, Yunlong Cui, Feng Fang, Wei Zhang, Tianqiang Song, Qiang Li, Xiaolin Zhu, Huichuan Sun & Ti Zhang. (2016) Metformin inhibits the prometastatic effect of sorafenib in hepatocellular carcinoma by upregulating the expression of TIP30. Cancer Science 107:4, pages 507-513.
Crossref
Krista C.J. Wink, José S.A. Belderbos, Edith M.T. Dieleman, Maddalena Rossi, Coen R.N. Rasch, Ronald A.M. Damhuis, Ruud M.A. Houben & Esther G.C. Troost. (2016) Improved progression free survival for patients with diabetes and locally advanced non-small cell lung cancer (NSCLC) using metformin during concurrent chemoradiotherapy. Radiotherapy and Oncology 118:3, pages 453-459.
Crossref
Tadashi Matsuoka, Hiroharu Shinozaki, Hiroki Ozawa, Ryo Nakanishi, Tetsuichiro Shimizu, Takashi Ishida, Toshiaki Terauchi, Masaru Kimata, Kenji Kobayashi & Yoshiro Ogata. (2016) Juvenile Rectal Cancer in a Family with Li-Fraumeni Syndrome. The Japanese Journal of Gastroenterological Surgery 49:11, pages 1170-1178.
Crossref
L. E. A. M. M. Spierings, S. M. Lagarde, M. G. H. van Oijen, S. S. Gisbertz, J. W. Wilmink, M. C. C. M. Hulshof, S. L. Meijer, M. C. Anderegg, M. I. van Berge Henegouwen & H. W. M. van Laarhoven. (2015) Metformin Use During Treatment of Potentially Curable Esophageal Cancer Patients is not Associated with Better Outcomes. Annals of Surgical Oncology 22:S3, pages 766-771.
Crossref
Li-Ru He, Wei Qiao, Zhong-Xing Liao, Ritsuko Komaki, Linus Ho, Wayne L Hofstetter & Steven H Lin. (2015) Impact of comorbidities and use of common medications on cancer and non-cancer specific survival in esophageal carcinoma. BMC Cancer 15:1.
Crossref
Aaron P. Thrift. (2015) Esophageal Adenocarcinoma: The Influence of Medications Used to Treat Comorbidities on Cancer Prognosis. Clinical Gastroenterology and Hepatology 13:13, pages 2225-2232.
Crossref
Sebastian Adeberg, Denise Bernhardt, Semi Ben Harrabi, Tilman Bostel, Angela Mohr, Christian Koelsche, Christian Diehl, Stefan Rieken & Juergen Debus. (2015) Metformin influences progression in diabetic glioblastoma patientsMetforminbeeinflusst die Progression bei diabetischen Glioblastompatienten. Strahlentherapie und Onkologie 191:12, pages 928-935.
Crossref
Walter Lemmo. (2014) Potential interactions of prescription and over‐the‐counter medications having antioxidant capabilities with radiation and chemotherapy. International Journal of Cancer 137:11, pages 2525-2533.
Crossref
Abbas Shafaee, Davood Zarei Dastyar, Jalil Pirayesh Islamian & Milad Hatamian. (2015) Inhibition of tumor energy pathways for targeted esophagus cancer therapy. Metabolism 64:10, pages 1193-1198.
Crossref
Marianne Koritzinsky. (2015) Metformin: A Novel Biological Modifier of Tumor Response to Radiation Therapy. International Journal of Radiation Oncology*Biology*Physics 93:2, pages 454-464.
Crossref
L. Van De Voorde, L. Janssen, R. Larue, R. Houben, J. Buijsen, M. Sosef, B. Vanneste, M.-C. Schraepen, M. Berbée & P. Lambin. (2015) Can metformin improve ‘the tomorrow’ of patients treated for oesophageal cancer?. European Journal of Surgical Oncology (EJSO) 41:10, pages 1333-1339.
Crossref
Dörthe Schaue & William H. McBride. (2015) Opportunities and challenges of radiotherapy for treating cancer. Nature Reviews Clinical Oncology 12:9, pages 527-540.
Crossref
Quinn Matthews, Martin Isabelle, Samantha J. Harder, Julian Smazynski, Wayne Beckham, Alexandre G. Brolo, Andrew Jirasek & Julian J. Lum. (2015) Radiation-Induced Glycogen Accumulation Detected by Single Cell Raman Spectroscopy Is Associated with Radioresistance that Can Be Reversed by Metformin. PLOS ONE 10:8, pages e0135356.
Crossref
Alexander Lin & Amit Maity. (2015) Molecular Pathways: A Novel Approach to Targeting Hypoxia and Improving Radiotherapy Efficacy via Reduction in Oxygen Demand. Clinical Cancer Research 21:9, pages 1995-2000.
Crossref
Geoff S. Higgins, Sean M. O’Cathail, Ruth J. Muschel & W. Gillies McKenna. (2015) Drug radiotherapy combinations: Review of previous failures and reasons for future optimism. Cancer Treatment Reviews 41:2, pages 105-113.
Crossref
Daniel R. Morales & Andrew D. Morris. (2015) Metformin in Cancer Treatment and Prevention. Annual Review of Medicine 66:1, pages 17-29.
Crossref
Haiwen Li, Xinggui Chen, Ying Yu, Zhennan Wang, Yufang Zuo, Shuhui Li, Donghong Yang, Shengwen Hu, Mei Xiang, Zumin Xu & Zhonghua Yu. (2014) Metformin inhibits the growth of nasopharyngeal carcinoma cells and sensitizes the cells to radiation via inhibition of the DNA damage repair pathway. Oncology Reports.
Crossref
Amato J. Giaccia. (2014) Molecular Radiobiology: The State of the Art. Journal of Clinical Oncology 32:26, pages 2871-2878.
Crossref
Aisha Fasih, Hosam A. Elbaz, Maik Hüttemann, Andre A. Konski & Steven P. Zielske. (2014) Radiosensitization of Pancreatic Cancer Cells by Metformin through the AMPK Pathway. Radiation Research 182:1, pages 50-59.
Crossref
Vlad C. Sandulache, John S. Hamblin, Heath D. Skinner, Mark W. Kubik, Jeffrey N. Myers & Jose P. Zevallos. (2014) Association between metformin use and improved survival in patients with laryngeal squamous cell carcinoma. Head & Neck 36:7, pages 1039-1043.
Crossref
Soichiro Honjo, Jaffer Ajani, Ailing Scott, Qiongrong Chen, Heath Skinner, John Stroehlein, Randy Johnson & Shumei Song. (2014) Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer. International Journal of Oncology.
Crossref
Y Feng, C Ke, Q Tang, H Dong, X Zheng, W Lin, J Ke, J Huang, S-CJ Yeung & H Zhang. (2014) Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling. Cell Death & Disease 5:2, pages e1088-e1088.
Crossref
Vlad C. Sandulache, Liangpeng Yang & Heath D. Skinner. 2014. Cancer Cell Signaling. Cancer Cell Signaling 3 9 .
Vanessa E. Zannella, Alan Dal Pra, Hala Muaddi, Trevor D. McKee, Shawn Stapleton, Jenna Sykes, Rachel Glicksman, Selim Chaib, Paul Zamiara, Michael Milosevic, Bradly G. Wouters, Robert G. Bristow & Marianne Koritzinsky. (2013) Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response. Clinical Cancer Research 19:24, pages 6741-6750.
Crossref
Tiange Wang, Guang Ning & Zachary Bloomgarden. (2013) Diabetes and cancer relationships (糖尿病与肿瘤的关联性). Journal of Diabetes 5:4, pages 378-390.
Crossref
Mariela A. Blum, Takashi Taketa, Kazuki Sudo, Roopma Wadhwa, Heath D. Skinner & Jaffer A. Ajani. (2013) Chemoradiation for Esophageal Cancer. Thoracic Surgery Clinics 23:4, pages 551-558.
Crossref
Claudia Becker, Christoph R. Meier, Susan S. Jick & Michael Bodmer. (2013) Case?control analysis on metformin and cancer of the esophagus. Cancer Causes & Control 24:10, pages 1763-1770.
Crossref
Michael Baumann, Stephan Bodis, Ekkehard Dikomey, Albert van der Kogel, Jens Overgaard, Hans Peter Rodemann & Bradly Wouters. (2013) Molecular radiation biology/oncology at its best: Cutting edge research presented at the 13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology. Radiotherapy and Oncology 108:3, pages 357-361.
Crossref
Hala Muaddi, Sanjana Chowdhury, Ravi Vellanki, Paul Zamiara & Marianne Koritzinsky. (2013) Contributions of AMPK and p53 dependent signaling to radiation response in the presence of metformin. Radiotherapy and Oncology 108:3, pages 446-450.
Crossref
Christos V. Rizos & Moses S. Elisaf. (2013) Metformin and cancer. European Journal of Pharmacology 705:1-3, pages 96-108.
Crossref
April D. Sorrell, Carin R. Espenschied, Julie O. Culver & Jeffrey N. Weitzel. (2013) Tumor Protein p53 (TP53) Testing and Li-Fraumeni Syndrome. Molecular Diagnosis & Therapy 17:1, pages 31-47.
Crossref

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