308
Views
40
CrossRef citations to date
0
Altmetric
Research Article

Synergistic Effect of Combined Growth Factors in Porcine Intervertebral Disc Degeneration

, , , , &
Pages 181-186 | Received 07 Nov 2012, Accepted 06 Feb 2013, Published online: 15 Apr 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Hao Yang, Fei Gao, Xiang Li, Jianru Wang, Hui Liu & Zhaomin Zheng. (2015) TGF-β1 antagonizes TNF-α induced up-regulation of matrix metalloproteinase 3 in nucleus pulposus cells: role of the ERK1/2 pathway. Connective Tissue Research 56:6, pages 461-468.
Read now

Articles from other publishers (39)

Xiaosong Zou, Xingmin Zhang, Song Han, Lin Wei, Zhi Zheng, Yongjie Wang, Jingguo Xin & Shaokun Zhang. (2023) Pathogenesis and therapeutic implications of matrix metalloproteinases in intervertebral disc degeneration: A comprehensive review. Biochimie 214, pages 27-48.
Crossref
Anran Zhang, Zhangrong Cheng, Yuhang Chen, Pengzhi Shi, Weikang Gan & Yukun Zhang. (2023) Emerging tissue engineering strategies for annulus fibrosus therapy. Acta Biomaterialia 167, pages 1-15.
Crossref
Shirley Tang, Connor Gantt, Ana Salazar Puerta, Lucy Bodine, Safdar Khan, Natalia Higuita‐Castro & Devina Purmessur. (2023) Nonviral overexpression of Scleraxis or Mohawk drives reprogramming of degenerate human annulus fibrosus cells from a diseased to a healthy phenotype. JOR SPINE.
Crossref
Hao Yu, Yun Teng, Jun Ge, Ming Yang, Haifeng Xie, Tianyi Wu, Qi Yan, Mengting Jia, Qing Zhu, Yanping Shen, Lianxue Zhang & Jun Zou. (2023) Isoginkgetin-loaded reactive oxygen species scavenging nanoparticles ameliorate intervertebral disc degeneration via enhancing autophagy in nucleus pulposus cells. Journal of Nanobiotechnology 21:1.
Crossref
Zhichao Li, Yan Wu, Guoqing Tan, Zhanwang Xu & Haipeng Xue. (2022) Exosomes and exosomal miRNAs: A new therapy for intervertebral disc degeneration. Frontiers in Pharmacology 13.
Crossref
Md Entaz Bahar, Jin Seok Hwang, Mahmoud Ahmed, Trang Huyen Lai, Trang Minh Pham, Omar Elashkar, Kazi-Marjahan Akter, Dong-Hee Kim, Jinsung Yang & Deok Ryong Kim. (2022) Targeting Autophagy for Developing New Therapeutic Strategy in Intervertebral Disc Degeneration. Antioxidants 11:8, pages 1571.
Crossref
Basanta Bhujel, Hae-Eun Shin, Dong-Jun Choi & Inbo Han. (2022) Mesenchymal Stem Cell-Derived Exosomes and Intervertebral Disc Regeneration: Review. International Journal of Molecular Sciences 23:13, pages 7306.
Crossref
Lin Lu, Aoshuang Xu, Fei Gao, Chenjun Tian, Honglin Wang, Jiayao Zhang, Yi Xie, Pengran Liu, Songxiang Liu, Cao Yang, Zhewei Ye & Xinghuo Wu. (2022) Mesenchymal Stem Cell-Derived Exosomes as a Novel Strategy for the Treatment of Intervertebral Disc Degeneration. Frontiers in Cell and Developmental Biology 9.
Crossref
Ayumu Kawakubo, Masayuki Miyagi, Yuji Yokozeki, Mitsufumi Nakawaki, Shotaro Takano, Masashi Satoh, Makoto Itakura, Gen Inoue, Masashi Takaso & Kentaro Uchida. (2022) Origin of M2 Mϕ and its macrophage polarization by TGF-β in a mice intervertebral injury model. International Journal of Immunopathology and Pharmacology 36, pages 039463202211037.
Crossref
Sobia Ekram, Shumaila Khalid, Asmat Salim & Irfan Khan. (2021) Regulating the fate of stem cells for regenerating the intervertebral disc degeneration. World Journal of Stem Cells 13:12, pages 1881-1904.
Crossref
Chang Kyu Lee, Dong Hwa Heo, Hungtae Chung, Eun Ji Roh, Anjani Darai, Jae Won Kyung, Hyemin Choi, Su Yeon Kwon, Basanta Bhujel & Inbo Han. (2021) Advances in Tissue Engineering for Disc Repair. Applied Sciences 11:4, pages 1919.
Crossref
Eun Roh, Anjani Darai, Jae Kyung, Hyemin Choi, Su Kwon, Basanta Bhujel, Kyoung Kim & Inbo Han. (2021) Genetic Therapy for Intervertebral Disc Degeneration. International Journal of Molecular Sciences 22:4, pages 1579.
Crossref
Yongjie Wang, Mingxue Che, Jingguo Xin, Zhi Zheng, Jiangbi Li & Shaokun Zhang. (2020) The role of IL-1β and TNF-α in intervertebral disc degeneration. Biomedicine & Pharmacotherapy 131, pages 110660.
Crossref
Matthew D. Harmon, Daisy M. Ramos, D. Nithyadevi, Rosalie Bordett, Swetha Rudraiah, Syam P. Nukavarapu, Isaac L. Moss & Sangamesh G. Kumbar. (2020) Growing a backbone – functional biomaterials and structures for intervertebral disc (IVD) repair and regeneration: challenges, innovations, and future directions. Biomaterials Science 8:5, pages 1216-1239.
Crossref
Leslie Frapin, Johann Clouet, Vianney Delplace, Marion Fusellier, Jérôme Guicheux & Catherine Le Visage. (2019) Lessons learned from intervertebral disc pathophysiology to guide rational design of sequential delivery systems for therapeutic biological factors. Advanced Drug Delivery Reviews 149-150, pages 49-71.
Crossref
S. Chen, S. Liu, K. Ma, L. Zhao, H. Lin & Z. Shao. (2019) TGF-β signaling in intervertebral disc health and disease. Osteoarthritis and Cartilage 27:8, pages 1109-1117.
Crossref
Taryn Saggese, Graciosa Q. Teixeira, Kelly Wade, Lydia Moll, Anita Ignatius, Hans-Joachim Wilke, Raquel M. Goncalves & Cornelia Neidlinger-Wilke. (2019) GEORG SCHMORL PRIZE OF THE GERMAN SPINE SOCIETY (DWG) 2018: combined inflammatory and mechanical stress weakens the annulus fibrosus: evidences from a loaded bovine AF organ culture. European Spine Journal 28:5, pages 922-933.
Crossref
Genglei Chu, Chen Shi, Huan Wang, Weidong Zhang, Huilin Yang & Bin Li. (2018) Strategies for Annulus Fibrosus Regeneration: From Biological Therapies to Tissue Engineering. Frontiers in Bioengineering and Biotechnology 6.
Crossref
Vonne M. van Heeswijk, Ashvin Thambyah, Peter A. Robertson & Neil D. Broom. (2018) Does an Annular Puncture Influence the Herniation Path?. Spine 43:7, pages 467-476.
Crossref
Jianjian Yin, Yongjing Huang, Gongming Gao, Luming Nong, Nanwei Xu & Dong Zhou. (2017) Changes and significance of inflammatory cytokines in a rat model of cervical spondylosis. Experimental and Therapeutic Medicine.
Crossref
Pei Li, Yibo Gan, Haoming Wang, Yuan Xu, Lei Song, Liyuan Wang, Bin Ouyang & Qiang Zhou. (2017) A Substance Exchanger-Based Bioreactor Culture of Pig Discs for Studying the Immature Nucleus Pulposus. Artificial Organs 41:11, pages E308-E319.
Crossref
Lianglong Pang, Pei Li, Ruijie Zhang, Yuan Xu, Lei Song & Qiang Zhou. (2017) Role of p38–MAPK pathway in the effects of high-magnitude compression on nucleus pulposus cell senescence in a disc perfusion culture. Bioscience Reports 37:5.
Crossref
Jian Chen, Jun Xuan, Yun-Tao Gu, Ke-Si Shi, Jun-Jun Xie, Jiao-Xiang Chen, Zeng-Ming Zheng, Yu Chen, Xi-Bang Chen, Yao-Sen Wu, Xiao-Lei Zhang & Xiang-Yang Wang. (2017) Celastrol reduces IL-1? induced matrix catabolism, oxidative stress and inflammation in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration in vivo. Biomedicine & Pharmacotherapy 91, pages 208-219.
Crossref
Pei Li, Ruijie Zhang, Liyuan Wang, Yibo Gan, Yuan Xu, Lei Song, Lei Luo, Chen Zhao, Chengmin Zhang, Bin Ouyang, Bing Tu & Qiang Zhou. (2017) Long-term load duration induces N-cadherin down-regulation and loss of cell phenotype of nucleus pulposus cells in a disc bioreactor culture. Bioscience Reports 37:2.
Crossref
Pei Li, Yibo Gan, Yuan Xu, Lei Song, Haoming Wang, Chengmin Zhang, Liyuan Wang, Chen Zhao, Lei Luo & Qiang Zhou. (2016) Matrix homeostasis within the immature annulus fibrosus depends on the frequency of dynamic compression: a study based on the self-developed mechanically active bioreactor. Biomechanics and Modeling in Mechanobiology 16:2, pages 385-394.
Crossref
Feng CaiLei ZhuFeng WangRui ShiXin-Hui XieXin HongXiao-Hu WangXiao-Tao Wu. (2017) The Paracrine Effect of Degenerated Disc Cells on Healthy Human Nucleus Pulposus Cells Is Mediated by MAPK and NF-κB Pathways and Can Be Reduced by TGF-β1. DNA and Cell Biology 36:2, pages 143-158.
Crossref
Pei Li, Ruijie Zhang & Qiang Zhou. (2017) Efficacy of Platelet-Rich Plasma in Retarding Intervertebral Disc Degeneration: A Meta-Analysis of Animal Studies. BioMed Research International 2017, pages 1-10.
Crossref
Cheng Wang, Xiaohua Yu, Yiguo Yan, Wei Yang, Shujun Zhang, Yongxiao Xiang, Jian Zhang & Wenjun Wang. (2017) Tumor necrosis factor-α: a key contributor to intervertebral disc degeneration. Acta Biochimica et Biophysica Sinica 49:1, pages 1-13.
Crossref
Zhen Li, Gernot Lang, Lindsay S. Karfeld-Sulzer, Kerstin T. Mader, R. Geoff Richards, Franz E. Weber, Chris Sammon, Hagit Sacks, Avner Yayon, Mauro Alini & Sibylle Grad. (2017) Heterodimeric BMP-2/7 for nucleus pulposus regeneration-In vitro and ex vivo studies. Journal of Orthopaedic Research 35:1, pages 51-60.
Crossref
Fenglong Sun, Yaohua Zhang & Qiang Li. (2016) Therapeutic mechanisms of ibuprofen, prednisone and betamethasone in osteoarthritis. Molecular Medicine Reports.
Crossref
Graciosa Q. Teixeira, Catarina Leite Pereira, Flávia Castro, Joana R. Ferreira, Maria Gomez-Lazaro, Paulo Aguiar, Mário A. Barbosa, Cornelia Neidlinger-Wilke & Raquel M. Goncalves. (2016) Anti-inflammatory Chitosan/Poly-γ-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc. Acta Biomaterialia 42, pages 168-179.
Crossref
Hongsik Cho, David C. HoltIIIIII, Richard Smith, Song-Ja Kim, Raymond J. Gardocki & Karen A. Hasty. (2016) The Effects of Platelet-Rich Plasma on Halting the Progression in Porcine Intervertebral Disc Degeneration. Artificial Organs 40:2, pages 190-195.
Crossref
Harold Llano Conrado, Jorge Rafael Hernández Santos, Sergio Tenopala Villegas, Cecilia Patricia Canseco Aguilar & Juan Carlos Torres Huertas. (2016) Efecto del plasma rico en plaquetas y/o factores de crecimiento sobre la regeneración y el dolor crónico asociado a discopatía intervertebral. Revisión sistemática. Revista de la Sociedad Española del Dolor.
Crossref
Inbo Han, Alexander E. Ropper, Deniz Konya, Serdar Kabatas, Zafer Toktas, Zaid Aljuboori, Xiang Zeng, John H. Chi, Ross Zafonte & Yang D. Teng. (2015) Biological Approaches to Treating Intervertebral Disk Degeneration: Devising Stem Cell Therapies. Cell Transplantation 24:11, pages 2197-2208.
Crossref
Wen-Jun Wang, Xiao-Hua Yu, Cheng Wang, Wei Yang, Wen-Si He, Shu-Jun Zhang, Yi-Guo Yan & Jian Zhang. (2015) MMPs and ADAMTSs in intervertebral disc degeneration. Clinica Chimica Acta 448, pages 238-246.
Crossref
Gianluca Fontana, Eugene See & Abhay Pandit. (2015) Current trends in biologics delivery to restore intervertebral disc anabolism. Advanced Drug Delivery Reviews 84, pages 146-158.
Crossref
Hongsik Cho, Andrew Walker, Jeb Williams & Karen A. Hasty. (2015) Study of Osteoarthritis Treatment with Anti-Inflammatory Drugs: Cyclooxygenase-2 Inhibitor and Steroids. BioMed Research International 2015, pages 1-10.
Crossref
Wei Li, Tianyi Liu, Liangliang Wu, Chun Chen, Zhiwei Jia, Xuedong Bai & Dike Ruan. (2014) Blocking the Function of Inflammatory Cytokines and Mediators by Using IL-10 and TGF-β: A Potential Biological Immunotherapy for Intervertebral Disc Degeneration in a Beagle Model. International Journal of Molecular Sciences 15:10, pages 17270-17283.
Crossref
Elias S. Vasiliadis, Spyros G. Pneumaticos, Demitrios S. Evangelopoulos & Athanasios G. Papavassiliou. (2014) Biologic Treatment of Mild and Moderate Intervertebral Disc Degeneration. Molecular Medicine 20:1, pages 400-409.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.