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Original Article

Chondroid Expression by Lapine Articular Chondrocytes in Spinner Culture Following Monolayer Growth

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Pages 127-136 | Received 14 Sep 1973, Published online: 07 Jul 2009

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Read on this site (11)

Margaret B. Aydelotte & Klaus E. Kuettner. (1988) Differences between sub-populations of cultured bovine articular chondrocytes. I. Morphology and cartilage matrix production. Connective Tissue Research 18:3, pages 205-222.
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RichardJ. Webber, StevenC. Dollins, Missy Harris & AubreyJ. Hough$suffix/text()$suffix/text(). (1985) Effect of alkyltins on rabbit articular and growth‐plate chondrocytes in monolayer culture. Journal of Toxicology and Environmental Health 16:2, pages 229-242.
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Charles J. Malemud, Roland W. Moskowitz & Victor M. Goldberg. (1984) Biosynthesis of Sulfated Proteoglycan in vitro by Cells Derived from Human Osteochondrophytic Spurs of the Femoral Head. Connective Tissue Research 12:3-4, pages 319-335.
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Peter C. Amadio, Michael G. Ehrlich & Henry J. Mankin. (1983) Matrix Synthesis in High Density Cultures of Bovine Epiphyseal Plate Chondrocytes. Connective Tissue Research 11:1, pages 11-19.
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Lee L. Getzy & Charles J. Malemud. (1982) Tissue and Organ Culture Studies of Cartilage. Journal of Histotechnology 5:1, pages 29-32.
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N. Fine, A. Harell, I. Binderman & N. Landshman. (1980) A Method for Processing Paraffin Sections of Multilayer Cultured Tissue. Stain Technology 55:3, pages 123-127.
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Douglas R. Miller, Benjamin V. Treadwell & Henry J. Mankin. (1980) De Novo Protein Synthesis by Human Chondrosarcoma in Cell and Organ Culture: Evidence of Unusually High Collagen Production by a Neoplastic Tissue. Connective Tissue Research 8:1, pages 9-20.
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Charles J. Malemud, David P. Norby & Leon Sokoloff. (1978) Explant Culture of Human and Rabbit Articular Chondrocytes. Connective Tissue Research 6:3, pages 171-179.
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Kjell Madsen, Stefan Lohmander, Stanislaw Moskalewski & Aleksander Hinek. (1978) Proteoglycans Synthesized by Fetal Guinea Pig Chondrocytes in Culture. Connective Tissue Research 5:4, pages 205-210.
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Aubrey J. Hough & Leon Sokoloff. (1975) Tissue Sampling as a Potential Source of Error in Experimental Studies of Cartilage. Connective Tissue Research 3:1, pages 27-31.
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Articles from other publishers (61)

Tannaz Tajsoleiman, Mohammad Abdekhodaie, Krist Gernaey & Ulrich Krühne. (2018) Efficient Computational Design of a Scaffold for Cartilage Cell Regeneration. Bioengineering 5:2, pages 33.
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Toshiaki Takahashi, Takamasa Nieda, Eriko Miyazaki & Hideaki Enzan. (2017) Novel Technique for Suspension Culture of Autologous Chondrocytes Improves Cell Proliferation and Tissue Architecture. Cell Transplantation 12:6, pages 667-676.
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Etsuo Chosa, Hiroaki Hamada, Kazuo Kitamura, Kenji Kuwasako, Toshihiko Yanagita, Tanenao Eto & Naoya Tajima. (2003) Expression of adrenomedullin and its receptor by chondrocyte phenotype cells. Biochemical and Biophysical Research Communications 303:1, pages 379-386.
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David G. Stokes, Gang Liu, Ibsen B. Coimbra, Sonsoles Piera‐Velazquez, Robert M. Crowl & Sergio A. Jiménez. (2002) Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis. Arthritis & Rheumatism 46:2, pages 404-419.
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Leon Sokoloff. (2001) Some highlights in the emergence of modern concepts of osteoarthritis. Seminars in Arthritis and Rheumatism 31:2, pages 71-107.
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Massimiliano Zanni, Antonio Tamburro & Domenico Rotilio. (1995) IL-1β and TGF-β1 modulate the sulphation grade of chondro-disaccharides in porcine articular cartilage: a capillary electrophoresis study. Journal of Lipid Mediators and Cell Signalling 12:1, pages 29-44.
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Paul E. DiCESARE, Matthias MORGELIN, Karlheinz MANN & Mats PAULSSON. (1994) Cartilage oligomeric matrix protein and thrombospondin 1. Purification from articular cartilage, electron microscopic structure, and chondrocyte binding. European Journal of Biochemistry 223:3, pages 927-937.
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Anthony M. Reginato, Renato V. Iozzo & Sergio A. Jimenez. (2005) Formation of nodular structures resembling mature articular cartilage in long–term primary cultures of human fetal epiphyseal chondrocytes on a hydrogel substrate. Arthritis & Rheumatism 37:9, pages 1338-1349.
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Charles J. Malemud. (1993) THE ROLE OF GROWTH FACTORS IN CARTILAGE METABOLISM. Rheumatic Disease Clinics of North America 19:3, pages 569-580.
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Van C. Mow & Farshid Guilak. 1993. Tissue Engineering. Tissue Engineering 128 145 .
Charles J. Malemud & Robert S. Papay. (1992) Synthesis of low buoyant density proteoglycans by human chondrocytes in culture. Matrix 12:6, pages 427-438.
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Alison M. Caswell, Weng S. Leong & R.Graham G. Russell. (1992) Interleukin-1β enhances the response of human articular chondrocytes to extracellular ATP. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1137:1, pages 52-58.
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S. B. Trippel, M. C. Whelan, M. Klagsbrun & S. R. Doctrow. (2005) Interaction of basic fibroblast growth factor with bovine growth plate chondrocytes. Journal of Orthopaedic Research 10:5, pages 638-646.
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Cornelia SCHMIDT, Barbara HENKEL, Ernst PÖSCHL, Haralabos ZORBAS, Werner G. PURSCHKE, Torsten R. GLOE & Peter K. MÜLLER. (2005) Complete cDNA sequence of chicken vigilin, a novel protein with amplified and evolutionary conserved domains. European Journal of Biochemistry 206:3, pages 625-634.
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Charles J. Malemud, Wendy Killeen, Thomas M. Hering & Anthony F. Purchio. (2005) Enhanced sulfated‐proteoglycan core protein synthesis by incubation of rabbit chondrocytes with recombinant transforming growth factor‐β 1 . Journal of Cellular Physiology 149:1, pages 152-159.
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Alison M. Caswell, Weng S. Leong & R. Graham G. Russell. (1991) Evidence for the presence of P2-purinoceptors at the surface of human articular chondrocytes in monolayer culture. Biochimica et Biophysica Acta (BBA) - General Subjects 1074:1, pages 151-158.
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Edward T. HarrisonJr.Jr., Frank P. Luyten & A.H. Reddi. (1991) Osteogenin promotes reexpression of cartilage phenotype by dedifferentiated articular chondrocytes in serum-free medium. Experimental Cell Research 192:2, pages 340-345.
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M. Adolphe, S. Thenet, F. Vincent & S. Demignot. (1991) Monolayer, tridimensional and immortalized cell line cultures as models in pharmacology and toxicology. Toxicology in Vitro 5:5-6, pages 367-371.
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Tatyana A. Belousova & Alexey Ye. Redkozubov. 1990. Sensory Systems and Communication in Arthropods. Sensory Systems and Communication in Arthropods 3 9 .
Alison M. Caswell & R.Graham G. Russell. (1988) Evidence that ecto-nucleoside-triphosphate pyrophosphatase serves in the generation of extracellular inorganic pyrophosphate in human bone and articular cartilage. Biochimica et Biophysica Acta (BBA) - General Subjects 966:3, pages 310-317.
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Fiona M. Watt & Jayesh Dudhia. (1988) Prolonged expression of differentiated phenotype by chondrocytes cultured at low density on a composite substrate of collagen and agarose that restricts cell spreading. Differentiation 38:2, pages 140-147.
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Fiona M. Watt. (1988) Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture. Journal of Cell Science 89:3, pages 373-378.
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M. Adolphe. 1987. 19 42 .
G.Richard Olds, Candace Finegan & Thomas F. Kresina. (1986) Dynamics of hepatic glycosaminoglycan accumulation in murine Schistosoma japonicum infection. Gastroenterology 91:6, pages 1335-1342.
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Charles J. Malemud, Teresa M. Mills, Rhonda Shuckett & Robert S. Papay. (2005) Stimulation of sulfated‐proteoglycan synthesis by forskolin in monolayer cultures of rabbit articular chondrocytes. Journal of Cellular Physiology 129:1, pages 51-59.
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Rhonda Shuckett & Charles J. Malemud. (1986) An In vitro model of ageing of human articular cartilage sulphated-proteoglycans. Mechanisms of Ageing and Development 34:1, pages 73-90.
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C. Bassleer, Ph. Gysen, J. M. Foidart, R. Bassleer & P. Franchimont. (1986) Human chondrocytes in tridimensional culture. In Vitro Cellular & Developmental Biology 22:3, pages 113-119.
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Alison M. Caswell & R.Graham G. Russell. (1985) Identification of ecto-nucleoside triphosphate pyrophosphatase in human articular chondrocytes in monolayer culture. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 847:1, pages 40-47.
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Y. Eilam, A. Beit-Or & Z. Nevo. (1985) Decrease in cytosolic free Ca2+ and enhanced proteoglycan synthesis induced by cartilage derived growth factors in cultured chondrocytes. Biochemical and Biophysical Research Communications 132:2, pages 770-779.
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Veronique Jouis, Jean Bocquet, Jean-Pierre Pujol, Martine Brisset & Gerard Loyau. (1985) Effect of asorbic acid on secreted proteoglycans from rabbit articular chondrocytes. FEBS Letters 186:2, pages 233-240.
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Charles J. Malemud & Robert S. Papay. (2005) The in vitro cell culture age and cell density of articular chondrocytes alter sulfated‐proteoglycan biosynthesis. Journal of Cellular Physiology 121:3, pages 558-568.
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Graeme K. Hunter, Cleo C. Rogakou & Kenneth P.H. Pritzker. (1984) Extracellular matrix synthesis by articular chondrocytes and synovial fibroblasts in long-term monolayer culture. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 804:4, pages 459-465.
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Jack M. Lipman, Cahir A. McDevitt & Leon Sokoloff. (1983) Xenografts of articular chondrocytes in the nude mouse. Calcified Tissue International 35:1, pages 767-772.
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C. J. Kirkpatrick & W. Mohr. (1983) A comparison of the effects of two gold-containing therapeutic agents on articular chondrocyte growth in vitro. Rheumatology International 3:2, pages 49-56.
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Barton L. Sachs, Victor M. Goldberg, Roland W. Moskowitz & Charles J. Malemud. (2005) Response of articular chondrocytes to pituitary fibroblst growth factor (FGF). Journal of Cellular Physiology 112:1, pages 51-59.
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Charles J. Malemud, Roland W. Moskowitz & Robert S. Papay. (1982) Correlation of the biosynthesis of prostaglandin and cyclic AMP in monolayer cultures of rabbit articular chondrocytes. Biochimica et Biophysica Acta (BBA) - General Subjects 715:1, pages 70-79.
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Charles J. Malemud & Roland W. Moskowitz. (1981) Physiology of Articular Cartilage. Clinics in Rheumatic Diseases 7:1, pages 29-55.
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Asher I. Sapolsky, Charles J. Malemud, David P. Norby, Roland W. Moskowitz, Kunio Matsuta & David S. Howell. (1981) Neutral proteinases from articular chondrocytes in culture. 2. Metal-dependent latent neutral proteoglycanase, and inhibitory activity. Biochimica et Biophysica Acta (BBA) - Enzymology 658:1, pages 138-147.
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Charles J. Malemud, Roland W. Moskowitz & Aviv Hassid. (1981) Prostaglandin biosynthesis by lapine articular chondrocytes in culture. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 663:2, pages 480-490.
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Charles J. Malemud, David P. Norby, Asher I. Sapolsky, Kunio Matsuta, David S. Howell & Roland W. Moskowitz. (1981) Neutral proteinases from articular chondrocytes in culture. I. A latent collagenase that degrades human cartilage type II collagen. Biochimica et Biophysica Acta (BBA) - Enzymology 657:2, pages 517-529.
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G. Speight, C.J. Handley & D.A. Lowther. (1981) Effect of dibutyryl cyclic AMP on the sulphation of proteoglycans by chondrocytes. Biochimica et Biophysica Acta (BBA) - General Subjects 672:1, pages 89-97.
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Lawrence Kent, Charles J. Malemud & Roland W. Moskowitz. (1980) Differential response of articular chondrocyte populations to thromboxane B2 and analogs of prostaglandin cyclic endoperoxides. Prostaglandins 19:3, pages 391-406.
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LEON SOKOLOFF. 1980. The Joints and Synovial Fluid. The Joints and Synovial Fluid 1 26 .
Kjell Madsen & Stefan Lohmander. (1979) Production of cartilage-typic proteoglycans in cultures of chondrocytes from elastic cartilage. Archives of Biochemistry and Biophysics 196:1, pages 192-198.
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R. P. Miller, M. Husain & S. Lohin. (2005) Long acting cAMP analogues enhance sulfate incorporation into matrix proteoglycans and suppress cell division of fetal rat chondrocytes in monolayer culture. Journal of Cellular Physiology 100:1, pages 63-76.
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J M Marsh, O W Wiebkin, S Gale, H Muir & R N Maini. (1979) Synthesis of sulphated proteoglycans by rheumatoid and normal synovial tissue in culture.. Annals of the Rheumatic Diseases 38:2, pages 166-170.
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. 1978. Developmental and Cellular Skeletal Biology. Developmental and Cellular Skeletal Biology 229 266 .
Richard J. Webber, Charles J. Malemud & Leon Sokoloff. (1977) Species differences in cell culture of mammalian articular chondrocytes. Calcified Tissue Research 23:1, pages 61-66.
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Ole W. Wiebkin & Helen Muir. (1977) Synthesis of proteoglycans by suspension and monolayer cultures of adult chondrocytes and de novo cartilage nodules-the effect of hyaluronic acid . Journal of Cell Science 27:1, pages 199-211.
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Charles J. Malemud & Leon Sokoloff. (1977) The effect of prostaglandins on cultured lapine articular chondrocytes. Prostaglandins 13:5, pages 845-860.
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David P. Norby, Charles J. Malemud & Leon Sokoloff. (2005) Differences in the collagen types synthesized by lapine articular chondrocytes in spinner and monolayer culture. Arthritis & Rheumatism 20:2, pages 709-716.
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CHARLES J. MALEMUD & DAVID P. NORBY. 1977. Cell Culture and its Application. Cell Culture and its Application 481 490 .
Kalindi DESHMUKH & Wayne G. KLINE. (2008) Characterization of Collagen and Its Precursors Synthesized by Rabbit‐Articular‐Cartilage Cells in Various Culture Systems. European Journal of Biochemistry 69:1, pages 117-123.
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S. Lohmander, S. Moskalewski, K. Madsen, J. Thyberg & U. Friberg. (1976) Influence of colchicine on the synthesis and secretion of proteoglycans and collagen by fetal guinea pig chondrocytes. Experimental Cell Research 99:2, pages 333-345.
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G. Lust, G. Nuki & J. E. Seegmiller. (1976) Inorganic pyrophosphate and proteoglycan metabolism in cultured human articular chondrocytes and fibroblasts. Arthritis & Rheumatism 19:S3, pages 479-487.
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Leon Sokoloff. (2006) Articular chondrocytes in culture. Matrix production and hormonal effects. Arthritis & Rheumatism 19:S3, pages 426-429.
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Charles J. Malemud & Aaron Janoff. (1975) HUMAN POLYMORPHONUCLEAR LEUKOCYTE ELASTASE AND CATHEPSIN G MEDIATE THE DEGRADATION OF LAPINE ARTICULAR CARTILAGE PROTEOGLYCAN. Annals of the New York Academy of Sciences 256:1 Mechanisms of, pages 254-262.
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O.W. Wiebkin, T.E. Hardingham & H. Muir. 1975. Extracellular Matrix Influences on Gene Expression. Extracellular Matrix Influences on Gene Expression 209 223 .
Charles J. Malemud & Leon Sokoloff. (2005) Some biological characteristics of a pituitary growth factor (CGF) for cultured lapine articular chondrocytes. Journal of Cellular Physiology 84:2, pages 171-179.
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