Citations (57)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Tommi Närhi, Ulrika Siitonen, Lauri J. Lehto, Mika M. Hyttinen, Jari P. A. Arokoski, Pieter A. Brama, Jukka S. Jurvelin, Heikki J. Helminen & Petro Julkunen. (2011) Minor Influence of Lifelong Voluntary Exercise on Composition, Structure, and Incidence of Osteoarthritis in Tibial Articular Cartilage of Mice Compared with Major Effects Caused by Growth, Maturation, and Aging. Connective Tissue Research 52:5, pages 380-392.
Read now
Read now
M. Margarida Espanha, Pirkko E. Lammi, Mika M. Hyttinen, Mikko J. Lammi & Heikki J. Helminen. (2001) Extracellular Matrix Composition of Full-Thickness Defect Repair Tissue is Little Influenced by Exercise in Rat Articular Cartilage. Connective Tissue Research 42:2, pages 97-109.
Read now
Read now
C. Anthony Poole, Tomohito Honda, Stephen J. M. Skinner, Jennifer R. Schofield, Karena F. Hyde & Hiroshi Shinkai. (1990) Chondrons From Articular Cartilage (II): Analysis of the Glycosaminoglycans in the Cellular Microenvironment of Isolated Canine Chondrons. Connective Tissue Research 24:3-4, pages 319-330.
Read now
Read now
Markku Tammi, Ilkka Kiviranta, Leena Peltonen, Jukka Jurvelin & Heikki J. Helminen. (1988) Effects of Joint Loading on Articular Cartilage Collagen Metabolism: Assay of Procollagen Prolyl 4-Hydroxylase and Galactosylhydroxylysyl Glucosyltransferase. Connective Tissue Research 17:3, pages 199-206.
Read now
Read now
Articles from other publishers (53)
Harriet G. Talbott, Richard A. Wilkins, Anthony C. Redmond, Claire L. Brockett & Marlène Mengoni. (2022) The relationship between subchondral bone cysts and cartilage health in the Tibiotalar joint: A finite element analysis. Clinical Biomechanics 99, pages 105745.
Crossref
Crossref
Masanori Watanabe, T. Mark Campbell, Katherine Reilly, Hans K. Uhthoff, Odette Laneuville & Guy Trudel. (2021) Bone replaces unloaded articular cartilage during knee immobilization. A longitudinal study in the rat. Bone 142, pages 115694.
Crossref
Crossref
Ahmed Salman, Atef Ibrahim Shabana, Dalia El-sayed El-ghazouly & Elbeltagy Maha. (2019) Protective effect of glucosamine and risedronate (alone or in combination) against osteoarthritic changes in rat experimental model of immobilized knee. Anatomy & Cell Biology 52:4, pages 498.
Crossref
Crossref
T.M. Campbell, K. Reilly, O. Laneuville, H. Uhthoff & G. Trudel. (2018) Bone replaces articular cartilage in the rat knee joint after prolonged immobilization. Bone 106, pages 42-51.
Crossref
Crossref
Momoko Nagai, Tomoki Aoyama, Akira Ito, Junichi Tajino, Hirotaka Iijima, Shoki Yamaguchi, Xiangkai Zhang & Hiroshi Kuroki. (2015) Alteration of cartilage surface collagen fibers differs locally after immobilization of knee joints in rats. Journal of Anatomy 226:5, pages 447-457.
Crossref
Crossref
D. L. Bader, D. M. Salter & T. T. Chowdhury. (2011) Biomechanical Influence of Cartilage Homeostasis in Health and Disease. Arthritis 2011, pages 1-16.
Crossref
Crossref
. 2011. Mechanobiology Handbook. Mechanobiology Handbook
199
226
.
Petro Julkunen, Esa P. Halmesmäki, Jarkko Iivarinen, Lassi Rieppo, Tommi Närhi, Juho Marjanen, Jarno Rieppo, Jari Arokoski, Pieter A. Brama, Jukka S. Jurvelin & Heikki J. Helminen. (2010) Effects of growth and exercise on composition, structural maturation and appearance of osteoarthritis in articular cartilage of hamsters. Journal of Anatomy 217:3, pages 262-274.
Crossref
Crossref
Bojana Obradovic, Milica Radisic & Gordana Vunjak-Novakovic. 2010. Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles. Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles
115
129
.
Yoshihiro Hagiwara, Akira Ando, Eiichi Chimoto, Yoshifumi Saijo, Kaori Ohmori‐Matsuda & Eiji Itoi. (2008) Changes of articular cartilage after immobilization in a rat knee contracture model. Journal of Orthopaedic Research 27:2, pages 236-242.
Crossref
Crossref
Y.-H. Tsuang, Y.-S. Lin, L.-T. Chen, C.-K. Cheng & J.-S. Sun. (2018) Effect of Dynamic Compression on in vitro Chondrocyte Metabolism. The International Journal of Artificial Organs 31:5, pages 439-449.
Crossref
Crossref
H. Moriyama, O. Yoshimura, S. Kawamata, K. Takayanagi, T. Kurose, A. Kubota, M. Hosoda & Y. Tobimatsu. (2008) Alteration in articular cartilage of rat knee joints after spinal cord injury. Osteoarthritis and Cartilage 16:3, pages 392-398.
Crossref
Crossref
Akira Ando, Yoshihiro Hagiwara, Eiichi Chimoto, Kouki Hatori, Yoshito Onoda & Eiji Itoi. (2008) Intra-articular Injection of Hyaluronan Diminishes Loss of Chondrocytes in a Rat Immobilized-Knee Model. The Tohoku Journal of Experimental Medicine 215:4, pages 321-331.
Crossref
Crossref
Petro Julkunen, Wouter Wilson, Jukka S. Jurvelin, Jarno Rieppo, Cheng-Juan Qu, Mikko J. Lammi & Rami K. Korhonen. (2008) Stress–relaxation of human patellar articular cartilage in unconfined compression: Prediction of mechanical response by tissue composition and structure. Journal of Biomechanics 41:9, pages 1978-1986.
Crossref
Crossref
Paul E. Mintken, Kristin J. Carpenter, Donald Eckhoff, Wendy M. Kohrt & Jennifer E. Stevens. (2007) Early Neuromuscular Electrical Stimulation to Optimize Quadriceps Muscle function Following Total Knee Arthroplasty: A Case Report. Journal of Orthopaedic & Sports Physical Therapy 37:7, pages 364-371.
Crossref
Crossref
R.I. Freshney, B. Obradovic, W. Grayson, C. Cannizzaro & Gordana Vunjak-Novakovic. 2007. Principles of Tissue Engineering. Principles of Tissue Engineering
155
183
.
Guy Trudel, Ko Himori & Hans K. Uhthoff. (2005) Contrasting alterations of apposed and unapposed articular cartilage during joint contracture formation. Archives of Physical Medicine and Rehabilitation 86:1, pages 90-97.
Crossref
Crossref
Norimasa Iwasaki, Shin-Tarou Yamane, Tokifumi Majima, Yasuhiko Kasahara, Akio Minami, Kazuo Harada, Sachiko Nonaka, Nobuhiko Maekawa, Hiroshi Tamura, Seiichi Tokura, Masamichi Shiono, Kenji Monde & Shin-Ichiro Nishimura. (2004) Feasibility of Polysaccharide Hybrid Materials for Scaffolds in Cartilage Tissue Engineering: Evaluation of Chondrocyte Adhesion to Polyion Complex Fibers Prepared from Alginate and Chitosan. Biomacromolecules 5:3, pages 828-833.
Crossref
Crossref
O D?marteau, D Wendt, A Braccini, M Jakob, D Sch?fer, M Heberer & I Martin. (2003) Dynamic compression of cartilage constructs engineered from expanded human articular chondrocytes. Biochemical and Biophysical Research Communications 310:2, pages 580-588.
Crossref
Crossref
Mohamed Sharawy, Ayman M. Ali & Won-Seok Choi. (2003) Experimental induction of anterior disk displacement of the rabbit craniomandibular joint: an immuno-electron microscopic study of collagen and proteoglycan occurrence in the condylar cartilage. Journal of Oral Pathology & Medicine 32:3, pages 176-184.
Crossref
Crossref
M. OKUMURA, G. H. KIM, M. TAGAMI, S. HARAMAKI & T. FUJINAGA. (2002) Serum Keratan Sulphate as a Cartilage Metabolic Marker in Horses: the Effect of Exercise. Journal of Veterinary Medicine Series A 49:4, pages 195-197.
Crossref
Crossref
Michael J MuellerKatrina S Maluf. (2002) Tissue Adaptation to Physical Stress: A Proposed “Physical Stress Theory” to Guide Physical Therapist Practice, Education, and Research. Physical Therapy 82:4, pages 383-403.
Crossref
Crossref
J.Z. Wu, W. Herzog & E.M. Hasler. (2002) Inadequate placement of osteochondral plugs may induce abnormal stress-strain distributions in articular cartilage - finite element simulations. Medical Engineering & Physics 24:2, pages 85-97.
Crossref
Crossref
Daria A. Narmoneva, Herman S. Cheung, Jean Y. Wang, David S. Howell & Lori A. Setton. (2002) Altered swelling behavior of femoral cartilage following joint immobilization in a canine model. Journal of Orthopaedic Research 20:1, pages 83-91.
Crossref
Crossref
M.A. Leroux, H.S. Cheung, J.L. Bau, J.Y. Wang, D.S. Howell & L.A. Setton. (2001) Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization. Osteoarthritis and Cartilage 9:7, pages 633-640.
Crossref
Crossref
Jussi Haapala, Jari P.A. Arokoski, Mika M. Hyttinen, Mikko Lammi, Markku Tammi, Vuokko Kovanen, Heikki J. Helminen & Ilkka Kiviranta. (1999) Remobilization Does Not Fully Restore Immobilization Induced Articular Cartilage Atrophy. Clinical Orthopaedics and Related Research 362, pages 218???229.
Crossref
Crossref
Gavin M. Brown, Thomas N. Huckerby, Michael T. Bayliss & Ian A. Nieduszynski. (1998) Human Aggrecan Keratan Sulfate Undergoes Structural Changes during Adolescent Development. Journal of Biological Chemistry 273:41, pages 26408-26414.
Crossref
Crossref
David A. Lee & Dan L. Bader. (1997) Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose. Journal of Orthopaedic Research 15:2, pages 181-188.
Crossref
Crossref
Lori A. Setton, Van C. Mow, Francisco J. Müller, J.C. Pita & David S. Howell. (1997) Mechanical behavior and biochemical composition of canine knee cartilage following periods of joint disuse and disuse with remobilization. Osteoarthritis and Cartilage 5:1, pages 1-16.
Crossref
Crossref
Peter A. Torzilli, Rita Grigiene, Charles Huang, Steven M. Friedman, Stephen B. Doty, Adele L. Boskey & George Lust. (1997) Characterization of cartilage metabolic response to static and dynamic stress using a mechanical explant test system. Journal of Biomechanics 30:1, pages 1-9.
Crossref
Crossref
Keith J. Gooch & Christopher J. Tennant. 1997. Mechanical Forces: Their Effects on Cells and Tissues. Mechanical Forces: Their Effects on Cells and Tissues
79
100
.
Kenji Takahashi, Toshikazu Kubo, Kappei Kobayashi, Jiro Imanishi, Masaharu Tkigawa, Yuji Arai & Yasusuke Hirasawa. (2005) Hydrostatic pressur influences mRNA exprssion of trnsforming growth factor‐β1 and heat shock protein 70 in chondrocyte‐like cell line. Journal of Orthopaedic Research 15:1, pages 150-158.
Crossref
Crossref
Ayman M Ali & Mohamed Sharawy. (1996) Histochemical and immunohistochemical studies of the effects of experimental anterior disc displacement on sulfated glycosaminoglycans, hyaluronic acid, and link protein of the rabbit craniomandibular joint. Journal of Oral and Maxillofacial Surgery 54:8, pages 992-1003.
Crossref
Crossref
M. Mohtai, M. K. Gupta, B. Donlon, B. Ellison, J. Cooke, G. Gibbons, D. J. Schurman & R. Lane Smith. (1996) Expression of interleukin-6 in osteoarthritic chondrocytes and effects of fluid-induced shear on this expression in normal human chondrocytesin vitro. Journal of Orthopaedic Research 14:1, pages 67-73.
Crossref
Crossref
David A. Lee & Daniel L. Bader. (1995) The development and characterization of anin vitro system to study strain-induced cell deformation in isolated chondrocytes. In Vitro Cellular & Developmental Biology - Animal 31:11, pages 828-835.
Crossref
Crossref
R. C. Haut, T. M. Ide & C. E. De Camp. (1995) Mechanical Responses of the Rabbit Patello-Femoral Joint to Blunt Impact. Journal of Biomechanical Engineering 117:4, pages 402-408.
Crossref
Crossref
Roberto S. Carvalho, Edwin H.K. Yen & D.M. Suga. (1995) Glycosaminoglycan synthesis in the rat articular disk in response to mechanical stress. American Journal of Orthodontics and Dentofacial Orthopedics 107:4, pages 401-410.
Crossref
Crossref
W.C. Puelacher, S.W. Kim, J.P. Vacanti, B. Schloo, D. Mooney & C.A. Vacanti. (1994) Tissue-engineered growth of cartilage: the effect of varying the concentration of chondrocytes seeded onto synthetic polymer matrices. International Journal of Oral and Maxillofacial Surgery 23:1, pages 49-53.
Crossref
Crossref
K. Puustj�rvi, T. Takala, W. Wang, M. Tammi, H. J. Helminen & V. Kovanen. (1993) Enhanced prolylhydroxylase activity in the posterior annulus fibrosus of canine intervertebral discs following long-term running exercise. European Spine Journal 2:3, pages 126-131.
Crossref
Crossref
R.S. Carvalho, E.H.K. Yen & D.M. Suga. (1993) The effect of growth on collagen and glycosaminoglycans in the articular disc of the rat temporomandibular joint. Archives of Oral Biology 38:6, pages 457-466.
Crossref
Crossref
M J Lammi, T P Hakkinen, J J Parkkinen, M M Hyttinen, M Jortikka, H J Helminen & M I Tammi. (1993) Adaptation of canine femoral head articular cartilage to long distance running exercise in young beagles.. Annals of the Rheumatic Diseases 52:5, pages 369-377.
Crossref
Crossref
M. J. Lammi, T. P. Häkkinen, J. J. Parkkinen, M. Hyttinen, M. Jortikka, H. J. Helminen & M. Tammi. 1993. Joint Destruction in Arthritis and Osteoarthritis. Joint Destruction in Arthritis and Osteoarthritis
95
99
.
ROBERT G. ROY, LARRY J. WALLACE, GARY R. JOHNSTON & STEVEN L. WICKSTROM. (2008) A Retrospective Evaluation of Stifle Osteoarthritis in Dogs with Bilateral Medial Patellar Luxation and Unilateral Surgical Repair. Veterinary Surgery 21:6, pages 475-479.
Crossref
Crossref
H. J. Helminen, I. Kiviranta, A.-M. Säämämen, J. Jurvelin, K. Paukkonen, J. Parkkinen, M. Lammi, J. Arokoski, T. Lapveteläinen, M. Hyttinen & M. Tammi. 1992. Wolff's Law and Connective Tissue Regulation. Wolff's Law and Connective Tissue Regulation.
R. Lane Smith, K. D. Thomas, D. J. Schurman, D. R. Carter, M. Wong & M. C. van der Meulen. (1992) Rabbit knee immobilization: Bone remodeling precedes cartilage degradation. Journal of Orthopaedic Research 10:1, pages 88-95.
Crossref
Crossref
Anna‐Marja Säämänen, Markku Tammi, Jukka Jurvelin, Ilkka Kiviranta & Heikki J. Helminen. (2005) Proteoglycan alterations following immobilization and remobilization in the articular cartilage of young canine knee (stifle) joint. Journal of Orthopaedic Research 8:6, pages 863-873.
Crossref
Crossref
Anna‐Marja Säämänen, Markku Tammi, Ilkka Kiviranta, Jukka Jurvelin & Heikki J. Helminen. (2005) Levels of chondroitin‐6‐sulfate and nonaggregating proteoglycans at articular cartilage contact sites in the knees of young dogs subjected to moderate running exercise. Arthritis & Rheumatism 32:10, pages 1282-1292.
Crossref
Crossref
Robert L.-Y. Sah, Young-Jo Kim, Joe-Yuan H. Doong, Alan J. Grodzinsky, Anna H. K. Plass & John D. Sandy. (1989) Biosynthetic response of cartilage explants to dynamic compression. Journal of Orthopaedic Research 7:5, pages 619-636.
Crossref
Crossref
Leroy Klein, Kingsbury G. Heiple, Peter A. Torzilli, Victor M. Goldberg & Albert H. Burstein. (2005) Prevention of ligament and meniscus atrophy by active joint motion in a non–weight‐bearing model. Journal of Orthopaedic Research 7:1, pages 80-85.
Crossref
Crossref
J JurvelinA-M SäämänenJ ArokoskiH J HelminenI KivirantaM Tammi. (2016) Biomechanical Properties of the Canine Knee Articular Cartilage as Related to Matrix Proteoglycans and Collagen. Engineering in Medicine 17:4, pages 157-162.
Crossref
Crossref
Mikko Lammi & Markku Tammi. (1988) Densitometric assay of nanogram quantities of proteoglycans precipitated on nitrocellulose membrane with Safranin O. Analytical Biochemistry 168:2, pages 352-357.
Crossref
Crossref
Anna-Marja S��m�nen & Markku Tammi. (1988) A sensitive GLC-method for component sugars andO-glycosidic linkage monosaccharides of cartilage proteoglycans. Glycoconjugate Journal 5:3, pages 235-243.
Crossref
Crossref
Harriet Talbott, Richard Wilkins, Anthony Redmond, Claire Brockett & Marlene Mengoni. (2022) The Relationship between Subchondral Bone Cysts and Cartilage Health in the Tibiotalar Joint: A Finite Element Analysis. SSRN Electronic Journal.
Crossref
Crossref