1,016
Views
42
CrossRef citations to date
0
Altmetric
Review Article

Amyloid in the islets of Langerhans: Thoughts and some historical aspects

Pages 81-89 | Received 16 Mar 2011, Accepted 17 Mar 2011, Published online: 13 Apr 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Gerardo J. Félix-Martínez, Aurelio N. Mata & J. Rafael Godínez-Fernández. (2020) Reconstructing human pancreatic islet architectures using computational optimization. Islets 12:6, pages 121-133.
Read now
Per Westermark, Gunilla T. Westermark, Ole B. Suhr & Svante Berg. (2014) Transthyretin-derived amyloidosis: Probably a common cause of lumbar spinal stenosis. Upsala Journal of Medical Sciences 119:3, pages 223-228.
Read now
Sara Bohman & Gunilla T. Westermark. (2012) Extensive amyloid formation in transplanted microencapsulated mouse and human islets. Amyloid 19:2, pages 87-93.
Read now
Per Westermark. (2012) Localized AL amyloidosis: A suicidal neoplasm?. Upsala Journal of Medical Sciences 117:2, pages 244-250.
Read now

Articles from other publishers (38)

Yongzhen Yang, Qin Wang, Gongjian Li, Wenjing Guo, Zuojun Yang, Hao Liu & Xiaoyuan Deng. (2023) Cysteine-Derived Chiral Carbon Quantum Dots: A Fibrinolytic Activity Regulator for Plasmin to Target the Human Islet Amyloid Polypeptide for Type 2 Diabetes Mellitus. ACS Applied Materials & Interfaces 15:2, pages 2617-2629.
Crossref
Qing-Rong Liu, Min Zhu, Qinghua Chen, Maja Mustapic, Dimitrios Kapogiannis & Josephine M. Egan. (2023) Novel Hominid-Specific IAPP Isoforms: Potential Biomarkers of Early Alzheimer’s Disease and Inhibitors of Amyloid Formation. Biomolecules 13:1, pages 167.
Crossref
Hiroaki Ueno, Weidong Zhang & Masamitsu Nakazato. (2022) Regulation of feeding and therapeutic application of bioactive peptides. Pharmacology & Therapeutics 239, pages 108187.
Crossref
Mathilde Fortier, Mélanie Côté-Cyr, Vy Nguyen, Margaryta Babych, Phuong Trang Nguyen, Roger Gaudreault & Steve Bourgault. (2022) Contribution of the 12–17 hydrophobic region of islet amyloid polypeptide in self-assembly and cytotoxicity. Frontiers in Molecular Biosciences 9.
Crossref
Vladan P. Bajic, Adil Salhi, Katja Lakota, Aleksandar Radovanovic, Rozaimi Razali, Lada Zivkovic, Biljana Spremo-Potparevic, Mahmut Uludag, Faroug Tifratene, Olaa Motwalli, Benoit Marchand, Vladimir B. Bajic, Takashi Gojobori, Esma R. Isenovic & Magbubah Essack. (2022) DES-Amyloidoses “Amyloidoses through the looking-glass”: A knowledgebase developed for exploring and linking information related to human amyloid-related diseases. PLOS ONE 17:7, pages e0271737.
Crossref
Mustafa Al Yaseen, Haider Al Zahid & Sawsan Al-Haroon. (2022) Amyloid Deposits in the Ligamentum Flavum Related to Lumbar Spinal Canal Stenosis and Lumbar Disc Degeneration. Cureus.
Crossref
Qing-Rong Liu, Min Zhu, Pingbo Zhang, Caio H. Mazucanti, Nicholas S. Huang, Doyle L. Lang, Qinghua Chen, Pavan Auluck, Stefano Marenco, Jennifer F. O’Connell, Luigi Ferrucci, Chee W. Chia & Josephine M. Egan. (2021) Novel Human Insulin Isoforms and Cα-Peptide Product in Islets of Langerhans and Choroid Plexus. Diabetes 70:12, pages 2947-2956.
Crossref
Qin Cao, David R. Boyer, Michael R. Sawaya, Romany Abskharon, Lorena Saelices, Binh A. Nguyen, Jiahui Lu, Kevin A. Murray, Fouad Kandeel & David S. Eisenberg. (2021) Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores. Nature Structural & Molecular Biology 28:9, pages 724-730.
Crossref
Masayoshi Tasaki, Francesca Lavatelli, Laura Obici, Konen Obayashi, Takeshi Miyamoto, Giampaolo Merlini, Giovanni Palladini, Yukio Ando & Mitsuharu Ueda. (2021) Age-related amyloidosis outside the brain: A state-of-the-art review. Ageing Research Reviews 70, pages 101388.
Crossref
Charles Eldrid, Aisha Ben-YounisJakub UjmaHannah Britt, Tristan CragnoliniSymeon KalfasDale Cooper-ShepherdNick TomczykKevin Giles, Mike MorrisRehana Akter, Daniel Raleigh & Konstantinos Thalassinos. (2021) Cyclic Ion Mobility–Collision Activation Experiments Elucidate Protein Behavior in the Gas Phase. Journal of the American Society for Mass Spectrometry 32:6, pages 1545-1552.
Crossref
Carmelo Tempra, Carmelo La Rosa & Fabio Lolicato. (2021) The role of alpha-helix on the structure-targeting drug design of amyloidogenic proteins. Chemistry and Physics of Lipids 236, pages 105061.
Crossref
Maho Ogoshi. 2021. Handbook of Hormones. Handbook of Hormones 425 427 .
Kamil Rozniakowski, Andrzej Fraczyk, Krystian Galecki, Joanna Wietrzyk, Beata Filip‐Psurska, Justyna Fraczyk, Zbigniew J. Kaminski & Beata Kolesinska. (2020) New Human Islet Amyloid Polypeptide Fragments Susceptible to Aggregation. Chemistry & Biodiversity 17:9.
Crossref
Pierre De Meyts & Pierre J. Lefèbvre. 2020. Hormonal Signaling in Biology and Medicine. Hormonal Signaling in Biology and Medicine 383 423 .
Larry M. Palato, Shannon Pilcher, Alissa Oakes, Arleen Lamba, Jaris Torres, Litza I. Ledesma Monjaraz, Crystabel Munoz, Edward Njoo, Dillon J. Rinauro, Kate Alexandra Menefee, Angela Tun, Betssy L. Jauregui, Sarah Shapiro, Olivia H. Nossiff, Eileen Olivares, Kevin Chang, Viviane Nguyen, Luiza A. Nogaj & David A. Moffet. (2019) Amyloidogenicity of naturally occurring full‐length animal IAPP variants. Journal of Peptide Science 25:8.
Crossref
George A. Edwards III, Nazaret Gamez, Gabriel Escobedo Jr.Olivia Calderon & Ines Moreno-Gonzalez. (2019) Modifiable Risk Factors for Alzheimer’s Disease. Frontiers in Aging Neuroscience 11.
Crossref
Idira Obasse, Mark Taylor, Nigel J. Fullwood & David Allsop. (2017) Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes. Interface Focus 7:6, pages 20160127.
Crossref
Phuong Trang Nguyen, Ximena Zottig, Mathew Sebastiao & Steve Bourgault. (2017) Role of Site-Specific Asparagine Deamidation in Islet Amyloid Polypeptide Amyloidogenesis: Key Contributions of Residues 14 and 21. Biochemistry 56:29, pages 3808-3817.
Crossref
Lydia M. Young, Ling-Hsien Tu, Daniel P. Raleigh, Alison E. Ashcroft & Sheena E. Radford. (2017) Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers. Chemical Science 8:7, pages 5030-5040.
Crossref
Marcia F. Kalin, Marcus Goncalves, Jennifer John-Kalarickal & Vivian Fonseca. 2017. Principles of Diabetes Mellitus. Principles of Diabetes Mellitus 1 11 .
Marcia F. Kalin, Marcus Goncalves, Jennifer John-Kalarickal & Vivian Fonseca. 2017. Principles of Diabetes Mellitus. Principles of Diabetes Mellitus 267 277 .
Kristin Folmert, Malgorzata Broncel, Hans v. Berlepsch, Christopher Hans Ullrich, Mary-Ann Siegert & Beate Koksch. (2016) Inhibition of peptide aggregation by means of enzymatic phosphorylation. Beilstein Journal of Organic Chemistry 12, pages 2462-2470.
Crossref
Soroku Yagihashi, Wataru Inaba & Hiroki Mizukami. (2015) Dynamic pathology of islet endocrine cells in type 2 diabetes: β‐Cell growth, death, regeneration and their clinical implications. Journal of Diabetes Investigation 7:2, pages 155-165.
Crossref
Phuong T. Nguyen, Rishi Sharma, Rabindra Rej, Carole Anne De Carufel, René Roy & Steve Bourgault. (2016) Low generation anionic dendrimers modulate islet amyloid polypeptide self-assembly and inhibit pancreatic β-cell toxicity. RSC Advances 6:80, pages 76360-76369.
Crossref
Maho Ogoshi. 2016. Handbook of Hormones. Handbook of Hormones 245 e27F-3 .
Marcia F. Kalin, Marcus Goncalves & Vivian Fonseca. 2016. Principles of Diabetes Mellitus. Principles of Diabetes Mellitus 1 11 .
Phuong Trang Nguyen, Nagore Andraka, Carole Anne De Carufel & Steve Bourgault. (2015) Mechanistic Contributions of Biological Cofactors in Islet Amyloid Polypeptide Amyloidogenesis. Journal of Diabetes Research 2015, pages 1-13.
Crossref
Lydia M. Young, Rachel A. Mahood, Janet C. Saunders, Ling-Hsien Tu, Daniel P. Raleigh, Sheena E. Radford & Alison E. Ashcroft. (2015) Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry. The Analyst 140:20, pages 6990-6999.
Crossref
Lydia M. Young, Janet C. Saunders, Rachel A. Mahood, Charlotte H. Revill, Richard J. Foster, Ling-Hsien Tu, Daniel P. Raleigh, Sheena E. Radford & Alison E. Ashcroft. (2014) Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry–mass spectrometry. Nature Chemistry 7:1, pages 73-81.
Crossref
Xiao-Dan Liu, Jin-Xue Ruan, Ji-Han Xia, Shu-Lin Yang, Jun-Hua Fan & Kui Li. (2014) The study of regulatory effects of Pdx-1, MafA and NeuroD1 on the activity of porcine insulin promoter and the expression of human islet amyloid polypeptide. Molecular and Cellular Biochemistry 394:1-2, pages 59-66.
Crossref
Cinthia Beskow Drachenberg & John C. Papadimitriou. 2014. Textbook of Organ Transplantation. Textbook of Organ Transplantation 989 1010 .
Lydia M. YoungPing Cao, Daniel P. Raleigh, Alison E. AshcroftSheena E. Radford. (2013) Ion Mobility Spectrometry–Mass Spectrometry Defines the Oligomeric Intermediates in Amylin Amyloid Formation and the Mode of Action of Inhibitors. Journal of the American Chemical Society 136:2, pages 660-670.
Crossref
Jonathan S. Wall, Angela Williams, Tina Richey, Alan Stuckey, Ying Huang, Craig Wooliver, Sallie Macy, Eric Heidel, Neil Gupta, Angela Lee, Brianna Rader, Emily B. Martin & Stephen J. Kennel. (2013) A Binding-Site Barrier Affects Imaging Efficiency of High Affinity Amyloid-Reactive Peptide Radiotracers In Vivo. PLoS ONE 8:6, pages e66181.
Crossref
Karen Pillay & Patrick Govender. (2013) Amylin Uncovered: A Review on the Polypeptide Responsible for Type II Diabetes. BioMed Research International 2013, pages 1-17.
Crossref
Gunilla T. Westermark, Alberto M. Davalli, Antonio Secchi, Franco Folli, Tatsuya Kin, Christian Toso, A. M. James Shapiro, Olle Korsgren, Gunnar Tufveson, Arne Andersson & Per Westermark. (2012) Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts. Transplantation 93:2, pages 219-223.
Crossref
Raghava Munivenkatappa, John C. Papadimitriou & Cinthia B. Drachenberg. (2012) Accelerated Pancreas Allograft Sclerosis Due to Allograft Rejection. Pathology Case Reviews 17:6, pages 229-235.
Crossref
Janine Seeliger & Roland Winter. 2012. Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease. Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease 185 209 .
Gunilla T. Westermark & Per Westermark. (2011) Localized amyloids important in diseases outside the brain - lessons from the islets of Langerhans and the thoracic aorta. FEBS Journal 278:20, pages 3918-3929.
Crossref