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Original Article

Local Inhibition of the Fibrinolytic System in Patients with Massive upper Gastrointestinal Hemorrhage

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Pages 173-178 | Received 05 Aug 1979, Published online: 18 Jan 2010

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Faisal Kamal, Muhammad Ali Khan, Wade Lee-Smith, Sachit Sharma, Zaid Imam, Dawit Jowhar, Ellen Petryna, Hemnishil K. Marella, Pavel Aksionav, Umair Iqbal, Claudio Tombazzi & Colin W. Howden. (2020) Efficacy and safety of tranexamic acid in acute upper gastrointestinal bleeding: meta-analysis of randomised controlled trials. Scandinavian Journal of Gastroenterology 55:12, pages 1390-1397.
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A. Berstad, K. Almodovar, K. Berstad, W. Anderson & B. I. Hirschowitz. (1988) Effect of Tranexamic Acid on Gastric Bleeding in Rats. Scandinavian Journal of Gastroenterology 23:4, pages 402-406.
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C. C.S. Staël Von Holstein, S. B. S. Eriksson & R. Kallen. (1987) Tranexamic Acid in Gastric and Duodenal Bleeding. Scandinavian Journal of Gastroenterology 22:sup137, pages 71-74.
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S. Isacson. (1987) Tranexamic Acid in Acute Upper Gastrointestinal Bleeding. Scandinavian Journal of Gastroenterology 22:sup137, pages 64-66.
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Articles from other publishers (17)

Joanna C. Dionne, Simon J. W. Oczkowski, Beverley J. Hunt, Massimo Antonelli, Marije Wijnberge, Senta Jorinde Raasveld & Alexander P. J. Vlaar. (2021) Tranexamic Acid in Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis. Critical Care Medicine 50:3, pages e313-e319.
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Alexander P. J. Vlaar, Joanna C. Dionne, Sanne de Bruin, Marije Wijnberge, S. Jorinde Raasveld, Frank E. H. P. van Baarle, Massimo Antonelli, Cecile Aubron, Jacques Duranteau, Nicole P. Juffermans, Jens Meier, Gavin J. Murphy, Riccardo Abbasciano, Marcella C. A. Müller, Marcus Lance, Nathan D. Nielsen, Herbert Schöchl, Beverley J. Hunt, Maurizio Cecconi & Simon Oczkowski. (2021) Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine. Intensive Care Medicine 47:12, pages 1368-1392.
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Po-Lin Lee, Kai-Suan Yang, Hong-Wei Tsai, Sen-Kuang Hou, Yi-No Kang & Chun-Chao Chang. (2021) Tranexamic acid for gastrointestinal bleeding: A systematic review with meta-analysis of randomized clinical trials. The American Journal of Emergency Medicine 45, pages 269-279.
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Eoghan Burke, Patricia Harkins & Ibrahim Ahmed. (2021) Is There a Role for Tranexamic Acid in Upper GI Bleeding? A Systematic Review and Meta-Analysis. Surgery Research and Practice 2021, pages 1-12.
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Erica Twum-Barimah, Ibtihal Abdelgadir, Morris Gordon & Anthony K. Akobeng. (2020) Systematic review with meta-analysis: the efficacy of tranexamic acid in upper gastrointestinal bleeding. Alimentary Pharmacology & Therapeutics 51:11, pages 1004-1013.
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Adnan Karadaş, Nurettin Özgür Doğan, Seda Güney Pinar, Olcay Yeşil, Murat Pekdemir, Serkan Yilmaz & Elif Yaka. (2020) A randomized controlled trial of the effects of local tranexamic acid on mortality, rebleeding, and recurrent endoscopy need in patients with upper gastrointestinal hemorrhage. European Journal of Gastroenterology & Hepatology 32:1, pages 26-31.
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Tim Nutbeam. (2015) In adult patients presenting as emergencies with upper gastrointestinal bleeding, does tranexamic acid decrease mortality?. African Journal of Emergency Medicine 5:2, pages 85-92.
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Cathy Bennett, Sarah Louise Klingenberg, Ebbe Langholz & Lise Lotte Gluud. (2014) Tranexamic acid for upper gastrointestinal bleeding. Cochrane Database of Systematic Reviews.
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Paul L. McCormack. (2012) Tranexamic Acid. Drugs 72:5, pages 585-617.
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Lise Lotte Gluud, Sarah Louise Klingenberg & Ebbe Langholz. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
L. L. GLUUD, S. L. KLINGENBERG & S. E. LANGHOLZ. (2008) Systematic review: tranexamic acid for upper gastrointestinal bleeding. Alimentary Pharmacology & Therapeutics 27:9, pages 752-758.
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Lise Lotte Gluud, Sarah Louise Klingenberg & Ebbe Langholz. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Javier P. Gisbert. (2006) Tratamiento farmacológico de la hemorragia digestiva por úlcera péptica. Medicina Clínica 127:2, pages 66-75.
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Gary R. Zuckerman & Paul E. Buse. (1991) Current Medical and Surgical Management of Nonvariceal Upper Gastrointestinal Bleeding. Gastrointestinal Endoscopy Clinics of North America 1:2, pages 263-289.
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D. A. Henry & D. L. O'Connell. (1989) Effects of fibrinolytic inhibitors on mortality from upper gastrointestinal haemorrhage.. BMJ 298:6681, pages 1142-1146.
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C C von Holstein, S B Eriksson & R Kallen. (1987) Tranexamic acid as an aid to reducing blood transfusion requirements in gastric and duodenal bleeding.. BMJ 294:6563, pages 7-10.
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D. R. Graham & R. J. Walker. (1982) Persistent gastrointestinal bleeding successfully treated with aminocaproic acid. Postgraduate Medical Journal 58:684, pages 658-661.
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