135
Views
26
CrossRef citations to date
0
Altmetric
Original Article

Evaluation of Possible Spinal Neurotoxicity of Clonidine

, &
Pages 266-273 | Published online: 18 Jan 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Samy Elsayed Hanoura, Rabei Hassanein Saad & Rajvir Singh. (2014) Dexmedetomidine improves intraoperative conditions and quality of postoperative analgesia when added to epidural in elective cesarean section. Egyptian Journal of Anaesthesia 30:4, pages 353-357.
Read now
Torsten Gordh & Per Hartvig. (1986) Cerebrospinal Fluid and Plasma Concentrations of Clonidine in Pigs after Epidural, Intravenous and Intramuscular Administration. Upsala Journal of Medical Sciences 91:3, pages 311-315.
Read now

Articles from other publishers (24)

S. Wiramus, A. Noël & F. Michel. (2017) Anestesia spinale nei bambini. EMC - Anestesia-Rianimazione 22:1, pages 1-9.
Crossref
S. Wiramus, A. Noël & F. Michel. (2017) Anestesias raquídeas en el niño. EMC - Anestesia-Reanimación 43:1, pages 1-10.
Crossref
Peter Marhofer & Chad M. Brummett. (2016) Safety and efficiency of dexmedetomidine as adjuvant to local anesthetics. Current Opinion in Anaesthesiology 29:5, pages 632-637.
Crossref
Rabie Soliman & Gomaa Zohry. (2016) Assessment the effect of fentanyl and dexmedetomidine as adjuvant to epidural bupivacaine in parturients undergoing normal labor. Journal of Anesthesiology and Clinical Science 5:1, pages 2.
Crossref
Suellen M. Walker, Marjorie Grafe & Tony L. Yaksh. (2012) Intrathecal Clonidine in the Neonatal Rat. Anesthesia & Analgesia 115:2, pages 450-460.
Crossref
Alexander Schnabel, Daniel M. Poepping, Esther M. Pogatzki-Zahn & Peter K. Zahn. (2011) Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials. Pediatric Anesthesia 21:12, pages 1219-1230.
Crossref
Uriah Guevara-López, J. Antonio Aldrete, Alfredo Covarrubias-Gómez, Rogelio E. Hernández-Pando & Francisco J. López-Muñoz. (2009) Absence of Histological Changes after the Administration of a Continuous Intrathecal Clonidine in Wistar rats. Pain Practice 9:2, pages 122-129.
Crossref
Chad M. Brummett, Mary A. Norat, John M. Palmisano & Ralph Lydic. (2008) Perineural Administration of Dexmedetomidine in Combination with Bupivacaine Enhances Sensory and Motor Blockade in Sciatic Nerve Block without Inducing Neurotoxicity in Rat. Anesthesiology 109:3, pages 502-511.
Crossref
Renata G S Dória, Carlos A A Valadão, Juan C Duque, Anderson Farias, Ricardo M Almeida & Augusto Castro Netto. (2008) Comparative study of epidural xylazine or clonidine in horses. Veterinary Anaesthesia and Analgesia 35:2, pages 166-172.
Crossref
Fabienne Perren, Eric Buchser, Dominique Chédel, Lorenz Hirt, Philippe Maeder & François Vingerhoets. (2004) Spinal cord lesion after long-term intrathecal clonidine and bupivacaine treatment for the management of intractable pain. Pain 109:1, pages 189-194.
Crossref
Salim Michel Hayek, Pushpa Nambi Joseph & Nagy A Mekhail. (2003) Pharmacology of intrathecally administered agents for treatment of spasticity and pain. Seminars in Pain Medicine 1:4, pages 238-253.
Crossref
Mark Ansermino, Rahul Basu, Christine Vandebeek & Carolyne Montgomery. (2003) Nonopioid additives to local anaesthetics for caudal blockade in children: a systematic review. Pediatric Anesthesia 13:7, pages 561-573.
Crossref
R De Rossi, Gisele V Bucker & Juliana V Varela. (2003) Perineal analgesic actions of epidural clonidine in cattle. Veterinary Anaesthesia and Analgesia 30:2, pages 63-70.
Crossref
Patricia Nance & Jay Meythaler. (1999) Intrathecal Drug Therapy. Physical Medicine and Rehabilitation Clinics of North America 10:2, pages 385-401.
Crossref
ANNETTE M. SYSEL, R. SCOTT PLEASANT, JOHN D. JACOBSON, H. DAVID MOLL, LORIN D. WARNICK, D. PHILLIP SPONENBERG & PETER EYRE. (2008) Systemic and Local Effects Associated With Long‐Term Epidural Catheterization and Morphine‐Detomidine Administration in Horses. Veterinary Surgery 26:2, pages 141-149.
Crossref
Samuel J. Hassenbusch. (1996) Epidural and subarachnoid administration of opioids for nonmalignant pain: Technical issues, current approaches and novel treatments. Journal of Pain and Symptom Management 11:6, pages 357-362.
Crossref
JM Malinovsky & M Pinaud. (1996) Neurotoxicité des agents administrés par voie intrathécale. Annales Françaises d'Anesthésie et de Réanimation 15:5, pages 647-658.
Crossref
D. Zech, R. Sabatowski, L. Badbruch & S. Grond. (1995) Hochdosierte intrathekale Clonidingabe in der Behandlung neuropathischer TumorschmerzenHigh-dose intrathecal clonidine in the treatment of neuropathic tumor pain. Two case reports. Der Schmerz 9:6, pages 305-311.
Crossref
Tony L. Yaksh, Juergen Jage & Yoshito Takano. (1993) Pharmacokinetics and pharmacodynamics of medullar agents. Bailli?re's Clinical Anaesthesiology 7:3, pages 597-614.
Crossref
Christopher W. Loomis, Devhuti Vyas & Stephen E. Sherman. (1992) Intrathecal oxymetazoline does not produce neurotoxicity in the spinal cord of the rat. Brain Research 599:1, pages 73-82.
Crossref
B. A. Svensson, A. Sottile & T. Gordh Jr. (2008) Studies on the development of tolerance and potential spinal neurotoxicity after chronic intrathecal carbachol‐antinociception in the rat. Acta Anaesthesiologica Scandinavica 35:2, pages 141-147.
Crossref
T. Gordh Jr. (2008) Epidural clonidine for treatment of postoperative pain after thoracotomy. A double‐blind placebo‐controlled study. Acta Anaesthesiologica Scandinavica 32:8, pages 702-709.
Crossref
DENNIS W. COOMBS. (1988) Intraspinal Analgesic Infusion by Implanted Pump. Annals of the New York Academy of Sciences 531:1 Neurological, pages 108-122.
Crossref
T.L. Yaksh, P.A.C. Durant, D.M. Gaumann, C.W. Stevens & Erling Mjanger. (1987) The use of receptor-selective agents as analgesics in the spinal cord: Trends and possibilities. Journal of Pain and Symptom Management 2:3, pages 129-138.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.