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Five cases of interstitial lung disease after leflunomide was combined with methotrexate therapy

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Pages 254-256 | Accepted 19 Nov 2013, Published online: 21 Mar 2014

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Yara Dadalti Fragoso & Joseph Bruno Bidin Brooks. (2015) Leflunomide and teriflunomide: altering the metabolism of pyrimidines for the treatment of autoimmune diseases. Expert Review of Clinical Pharmacology 8:3, pages 315-320.
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Ji-Won Kim, Sang Wan Chung, Jung Yoon Pyo, Sung Hae Chang, Min Uk Kim, Chan Ho Park, Ji Sung Lee, Jeong Seok Lee, You-Jung Ha, Eun Ha Kang, Yeon-Ah Lee, Yong-Beom Park, Eun Young Lee & Jung-Yoon Choe. (2023) Methotrexate, leflunomide and tacrolimus use and the progression of rheumatoid arthritis-associated interstitial lung disease. Rheumatology 62:7, pages 2377-2385.
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C. Fiehn, J. Leipe, C. Weseloh, R. Bergner & K. Krüger. (2023) Bewertung von Wechselwirkungen und Dosierungsempfehlungen von synthetischen DMARDs – Evidenz- und konsensbasierte Empfehlungen auf Basis einer systematischen LiteratursucheAssessment of interactions and dosage recommendations of synthetic DMARDs—Evidence-based and consensus-based recommendations based on a systematic literature search. Zeitschrift für Rheumatologie 82:2, pages 151-162.
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G. I. Gridneva, E. S. Aronova, A. V. Kudryavtseva & G. V. Lukina. (2021) Leflunomide: modern look at safety problem (literature review). Medical alphabet:16, pages 16-19.
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Zhang Wang, Jiaqi Wu, Dongyun Li, Xuan Tang, Yue Zhao, Xiao Cai, Xianghong Chen, Xiumin Chen, Qingchun Huang & Runyue Huang. (2020) Traditional Chinese medicine Biqi capsule compared with leflunomide in combination with methotrexate in patients with rheumatoid arthritis: a randomized controlled trial. Chinese Medicine 15:1.
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Wanying Wang, Hua Zhou & Liang Liu. (2020) The role of Chinese herbal medicine in the management of adverse drug reactions of leflunomide in treating rheumatoid arthritis. Phytomedicine 68, pages 153136.
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Luisa Klotz, Joachim Havla, Nicholas Schwab, Reinhard Hohlfeld, Michael Barnett, Stephen Reddel & Heinz Wiendl. (2019) Risks and risk management in modern multiple sclerosis immunotherapeutic treatment. Therapeutic Advances in Neurological Disorders 12, pages 175628641983657.
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Bridget Hodkinson, Kingsley Ross Magomero & Mohammed Tikly. (2016) Combination leflunomide and methotrexate in refractory rheumatoid arthritis: a biologic sparing approach. Therapeutic Advances in Musculoskeletal Disease 8:5, pages 172-179.
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Calvin J. Meaney. 2015. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 471 490 .
. (2014) Leflunomide/methotrexate. Reactions Weekly 1532:1, pages 136-136.
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