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Scandinavian Journal of Rheumatology Volume 25, 1996 - Issue 4
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Original Article

Randomized, Placebo Controlled Trial of Withdrawal of Slow-acting Antirheumatic Drugs and of Observer Bias in Rheumatoid Arthritis

P. C. Gøtzsche Departments of Rheumatology, Hvidovre Hospital, Sweden
,
M. Hansen Departments of Rheumatology, Hvidovre Hospital, Sweden
,
M. Stoltenberg Departments of Rheumatology, Hvidovre Hospital, Sweden
,
A. Svendsen Odense University Hospital, Sweden
,
J. Beier Odense University Hospital, Sweden
,
K. L. Faarvang Rigshospitalet, Sweden
,
M. Wangel Gråsten Arthritis Hospital, Sweden
,
L. Rydgren Lund University Hospital, Sweden
,
P. Halberg Departments of Rheumatology, Hvidovre Hospital, Sweden
,
P. Juncker Odense University Hospital, Sweden
,
V. Andersen Rigshospitalet, Sweden
,
T. Mørk Hansen Herlev Hospital, Denmark
&
L. Endahl the University of Copenhagen, Denmark
 show all
Pages 194-199 | Received 27 Oct 1995, Accepted 12 Mar 1996, Published online: 12 Jul 2009

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Alfonso E Bello, Elizabeth L Perkins, Randy Jay & Petros Efthimiou. (2017) Recommendations for optimizing methotrexate treatment for patients with rheumatoid arthritis. Open Access Rheumatology: Research and Reviews 9, pages 67-79.
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Fabiola Atzeni, Maurizio Benucci, Rossella Talotta, Ignazio Francesco Masala, Piercarlo Sarzi-Puttini & Marcello Govoni. (2016) What are the dangers of biological therapy discontinuation or dose reduction strategies when treating rheumatoid arthritis?. Expert Review of Clinical Pharmacology 9:11, pages 1403-1411.
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Sujith Subesinghe & Ian C Scott. (2015) Key findings from studies of methotrexate tapering and withdrawal in rheumatoid arthritis. Expert Review of Clinical Pharmacology 8:6, pages 751-760.
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Articles from other publishers (13)

Hanna Gul, Kate Harnden & Benazir Saleem. (2021) Defining the Optimal Strategies for Achieving Drug-Free Remission in Rheumatoid Arthritis: A Narrative Review. Healthcare 9:12, pages 1726.
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M. Schneider, G. Baseler, O. Funken, S. Heberger, U. Kiltz, P. Klose, K. Krüger, J. Langhorst, W. Mau, R. Oltman, B. Richter, S. Seitz, P. Sewerin, R. Tholen, C. Weseloh, M. Witthöft & C. Specker. (2020) Management der frühen rheumatoiden ArthritisManagement of early rheumatoid arthritis. Zeitschrift für Rheumatologie 79:S1, pages 1-38.
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Elise van Mulligen, Pascal Hendrik Pieter de Jong, Tjallingius Martijn Kuijper, Myrthe van der Ven, Cathelijne Appels, Casper Bijkerk, Joop B Harbers, Yael de Man, T H Esmeralda Molenaar, Ilja Tchetverikov, Yvonne P M Goekoop-Ruiterman, Jende van Zeben, Johanna M W Hazes, Angelique E A M Weel & Jolanda J Luime. (2019) Gradual tapering TNF inhibitors versus conventional synthetic DMARDs after achieving controlled disease in patients with rheumatoid arthritis: first-year results of the randomised controlled TARA study. Annals of the Rheumatic Diseases 78:6, pages 746-753.
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Bruno Fautrel. (2018) Therapeutic strategy for rheumatoid arthritis patients who have achieved remission. Joint Bone Spine 85:6, pages 679-685.
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Bruno Fautrel. (2018) Que faire une fois la rémission obtenue dans la polyarthrite rhumatoïde. Revue du Rhumatisme Monographies 85:1, pages 25-31.
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Deepti Saxena, Michael Spino, Fernando Tricta, John Connelly, Bernadette M. Cracchiolo, Axel-Rainer Hanauske, Darlene D’Alliessi Gandolfi, Michael B. Mathews, Jonathan Karn, Bart Holland, Myung Hee Park, Tsafi Pe’ery, Paul E. Palumbo & Hartmut M. Hanauske-Abel. (2016) Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial. PLOS ONE 11:5, pages e0154842.
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Bruno Fautrel & Alfons A. den Broeder. (2015) De-intensifying treatment in established rheumatoid arthritis (RA): Why, how, when and in whom can DMARDs be tapered?. Best Practice & Research Clinical Rheumatology 29:4-5, pages 550-565.
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CLIFTON O. BINGHAMIIIIII, CHRISTOPH POHL, THASIA G. WOODWORTH, SARAH E. HEWLETT, JAMES E. MAY, MAHBOOB U. RAHMAN, JAMES P. WITTER, DANIEL E. FURST, C. VIBEKE STRAND, MAARTEN BOERS & RIEKE E. ALTEN. (2009) Developing a Standardized Definition for Disease “Flare” in Rheumatoid Arthritis (OMERACT 9 Special Interest Group): Table 1.. The Journal of Rheumatology 36:10, pages 2335-2341.
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Z. L. McLaren, V. E. Abernethy & J. K. Dawson. (2009) Comment on: British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of rheumatoid arthritis (after the first 2 years). Rheumatology 48:9, pages 1178-1179.
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Mark J. Ratain, Tim Eisen, Walter M. Stadler, Keith T. Flaherty, Stan B. Kaye, Gary L. Rosner, Martin Gore, Apurva A. Desai, Amita Patnaik, Henry Q. Xiong, Eric Rowinsky, James L. Abbruzzese, Chenghua Xia, Ronit Simantov, Brian Schwartz & Peter J. O'Dwyer. (2006) Phase II Placebo-Controlled Randomized Discontinuation Trial of Sorafenib in Patients With Metastatic Renal Cell Carcinoma. Journal of Clinical Oncology 24:16, pages 2505-2512.
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Lynden J RobertsLeslie G ClelandSusanna M ProudmanRanjeny Thomas. (2006) Early combination disease modifying antirheumatic drug treatment for rheumatoid arthritis. Medical Journal of Australia 184:3, pages 122-125.
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V. Strand, S. Cohen, B. Crawford, J. S. Smolen & D. L. Scott. (2004) Patient-reported outcomes better discriminate active treatment from placebo in randomized controlled trials in rheumatoid arthritis. Rheumatology 43:5, pages 640-647.
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. (1997) Treatment of Rheumatoid Arthritis with a Tumor Necrosis Factor Receptor–Fc Fusion Protein. New England Journal of Medicine 337:21, pages 1559-1561.
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