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Scandinavian Journal of Rheumatology Volume 25, 1996 - Issue 1
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Review Article

The Role of T-lymphocytes and Cytokines in Rheumatoid Arthritis

J. S. Smolen 2nd Department of Medicine, Lainz Hospital and Dept. of Rheumatology, Univ. of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Rheumatology, Vienna, Austria
,
M. Tohidast-Akrad Ludwig Boltzmann Institute for Rheumatology, Vienna, Austria
,
A. Gal Department of Molecular Biology at the, National Institute for Rheumatology, Budapest, Hungary
,
M. Kunaver 2nd Department of Medicine, Lainz Hospital and Dept. of Rheumatology, Univ. of Vienna, Vienna, Austria
,
G. Eberl 2nd Department of Medicine, Lainz Hospital and Dept. of Rheumatology, Univ. of Vienna, Vienna, Austria
,
P. Zenz Department of Orthopedic Surgery, Hospital Baumgartner Hone, Vienna, Austria
,
A. Falus Department of Molecular Biology at the, National Institute for Rheumatology, Budapest, Hungary
&
G. Steiner Ludwig Boltzmann Institute for Rheumatology, Vienna, Austria
 show all
Pages 1-4 | Received 01 Sep 1995, Published online: 12 Jul 2009

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David S Gibson, Michael J Bustard, Cathy M McGeough, Helena A Murray, Martin A Crockard, Andrew McDowell, Jayne K Blayney, Philip V Gardiner & Anthony J Bjourson. (2015) Current and future trends in biomarker discovery and development of companion diagnostics for arthritis. Expert Review of Molecular Diagnostics 15:2, pages 219-234.
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M Sugiyama, M Funauchi, T Yamagata, Y Nozaki, BS Yoo, S Ikoma, K Kinoshita & A Kanamaru. (2004) Predominant inhibition of Th1 cytokines in New Zealand black/white F1 mice treated with FK506. Scandinavian Journal of Rheumatology 33:2, pages 108-114.
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Andrew Alldred & Paul Emery. (2001) Leflunomide: a novel DMARD for the treatment of rheumatoid arthritis. Expert Opinion on Pharmacotherapy 2:1, pages 125-137.
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J. S. Smolen. (1999) Efficacy and safety of the new DMARD leflunomide: Comparison to placebo and sulfasalazine in active rheumatoid arthritis. Scandinavian Journal of Rheumatology 28:112, pages 15-21.
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Articles from other publishers (31)

Rosanna Dammacco, Silvana Guerriero, Giovanni Alessio & Franco Dammacco. (2021) Natural and iatrogenic ocular manifestations of rheumatoid arthritis: a systematic review. International Ophthalmology 42:2, pages 689-711.
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Zhenqiang Yao & Brendan F. Boyce. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 200 220 .
Amit Sandhu, Shabeer Ahmad, Prabhdeep Kaur, Archana Bhatnagar, Veena Dhawan & Varun Dhir. (2018) Methotrexate preferentially affects Tc1 and Tc17 subset of CD8 T lymphocytes. Clinical Rheumatology 38:1, pages 37-44.
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Fumihiko Miyoshi, Kojiro Sato & Toshihide Mimura. (2016) Changes in the pattern of cytokine production from peripheral blood mononuclear cells in patients with rheumatoid arthritis treated with infliximab and their relation to plasma arginase activity. International Journal of Rheumatic Diseases 21:11, pages 1907-1914.
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Sang Yeob Lee, Sung Won Lee & Won Tae Chung. (2018) Dystrophic calcinosis in a patient with overlap syndrome (scleroderma and rheumatoid arthritis) treated by leflunomide. Medicine 97:47, pages e13319.
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I-Tsu Chyuan, Hwei-Fang Tsai, Hsiu-Jung Liao, Chien-Sheng Wu & Ping-Ning Hsu. (2017) An apoptosis-independent role of TRAIL in suppressing joint inflammation and inhibiting T-cell activation in inflammatory arthritis. Cellular & Molecular Immunology 15:9, pages 846-857.
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Gary F. Bouloux. (2018) The Use of Synovial Fluid Analysis for Diagnosis of Temporomandibular Joint Disorders. Oral and Maxillofacial Surgery Clinics of North America 30:3, pages 251-256.
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Ling Zhao, Zhenyu Jiang, Yanfang Jiang, Ning Ma, Yandong Zhang, Li Feng & Kai Wang. (2013) IL-22 + CD4 + T cells in patients with rheumatoid arthritis . International Journal of Rheumatic Diseases 16:5, pages 518-526.
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Jian Sun, Yuan Jia, Ru Li, Jianping Guo, Xiaolin Sun, Yanying Liu, Yingni Li, Haihong Yao, Xia Liu, Jing Zhao & Zhanguo Li. (2011) Altered influenza virus haemagglutinin (HA)-derived peptide is potent therapy for CIA by inducing Th1 to Th2 shift. Cellular & Molecular Immunology 8:4, pages 348-358.
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Cheng-Hao Jin, Su Young Chae, Tae Hyung Kim, Han-Kwang Yang, Eun Young Lee, Yeong Wook Song, Dong-Gyu Jo & Kang Choon Lee. (2010) Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand on the Reduction of Joint Inflammation in Experimental Rheumatoid Arthritis. Journal of Pharmacology and Experimental Therapeutics 332:3, pages 858-865.
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Kojiro Sato. (2008) Th17 Cells and Rheumatoid Arthritis—From the Standpoint of Osteoclast Differentiation—. Allergology International 57:2, pages 109-114.
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Kojiro SATO. (2008) . KAGAKU TO SEIBUTSU 46:5, pages 310-315.
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Katsuhide Okunishi, Makoto Dohi, Keishi Fujio, Kazuyuki Nakagome, Yasuhiko Tabata, Takahiro Okasora, Makoto Seki, Mihoko Shibuya, Mitsuru Imamura, Hiroaki Harada, Ryoichi Tanaka & Kazuhiko Yamamoto. (2007) Hepatocyte Growth Factor Significantly Suppresses Collagen-Induced Arthritis in Mice. The Journal of Immunology 179:8, pages 5504-5513.
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M. Saha, D. Shipley, S. McBride, C. Kennedy & F. Vega-Lopez. (2006) Atypical cutaneous leishmaniasis in two patients receiving low-dose methotrexate. British Journal of Dermatology 155:4, pages 830-833.
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Kojiro Sato & Hiroshi Takayanagi. (2006) Osteoclasts, rheumatoid arthritis, and osteoimmunology. Current Opinion in Rheumatology 18:4, pages 419-426.
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Josef S. Smolen & Günter Steiner. (2003) Therapeutic strategies for rheumatoid arthritis. Nature Reviews Drug Discovery 2:6, pages 473-488.
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Kathleen J. Smith & Henry Skelton. (2003) Acute onset of neutrophilic dermatosis in patients after therapy with a COX-2-specific inhibitor. International Journal of Dermatology 42:5, pages 389-393.
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Heather M. Burke, Alex J. Zautra, Mary C. Davis, Amy S. Schultz & John W. Reich. 2003. Handbook of Psychology. Handbook of Psychology.
Ruth Fritsch, Daniela Eselböck, Karl Skriner, Beatrice Jahn-Schmid, Clemens Scheinecker, Barbara Bohle, Makiyeh Tohidast-Akrad, Silvia Hayer, Josef Neumüller, Serafin Pinol-Roma, Josef S. Smolen & Günter Steiner. (2002) Characterization of Autoreactive T Cells to the Autoantigens Heterogeneous Nuclear Ribonucleoprotein A2 (RA33) and Filaggrin in Patients with Rheumatoid Arthritis. The Journal of Immunology 169:2, pages 1068-1076.
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Robert I. Fox. (2002) New Developments in Laboratory Tests and Therapy for Rheumatoid Arthritis. Laboratory Medicine 33:7, pages 543-550.
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Ann VanderBorght, Piet Geusens, Jef Raus & Piet Stinissen. (2001) The autoimmune pathogenesis of rheumatoid arthritis: Role of autoreactive T cells and new immunotherapies. Seminars in Arthritis and Rheumatism 31:3, pages 160-175.
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Cristina López-Rodrı́guez, José Aramburu, Lei Jin, Andrew S Rakeman, Mayako Michino & Anjana Rao. (2001) Bridging the NFAT and NF-κB Families. Immunity 15:1, pages 47-58.
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Johannes Grisar, Philipp Hahn, Susanne Brosch, Meinrad Peterlik, Josef S Smolen & Peter Pietschmann. (2001) Phenotypic characteristics of human monocytes undergoing transendothelial migration. Arthritis Research & Therapy 3:2.
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Georg Schett, Makiyeh Tohidast-Akrad, Günter Steiner & Josef Smolen. (2001) The stressed synovium. Arthritis Research & Therapy 3:2.
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Niels C Pedersen. (1999) A review of immunologic diseases of the dog. Veterinary Immunology and Immunopathology 69:2-4, pages 251-342.
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Josef S Smolen, Joachim R Kalden, David L Scott, Blaz Rozman, Tore K Kvien, Arvi Larsen, Iris Loew-Friedrich, Christine Oed & Ronald Rosenburg. (1999) Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial. The Lancet 353:9149, pages 259-266.
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Michael V. Volin, Manisha R. Shah, Michihide Tokuhira, G.Kenneth HainesIIIIII, James M. Woods & Alisa E. Koch. (1998) RANTES Expression and Contribution to Monocyte Chemotaxis in Arthritis. Clinical Immunology and Immunopathology 89:1, pages 44-53.
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Hans P. Kiener, Mehrdad Baghestanian, Martin Dominkus, Sabine Walchshofer, Minoo Ghannadan, Martin Willheim, Christian Sillaber, Winfried B. Graninger, Josef S. Smolen & Peter Valent. (1998) Expression of the C5a receptor (CD88) on synovial mast cells in patients with rheumatoid arthritis. Arthritis & Rheumatism 41:2, pages 233-245.
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Danielle Burger & Jean-Michel Dayer. 1998. T Cells in Arthritis. T Cells in Arthritis 111 128 .
Antonio La Cava & Salvatore Albani. 1998. Encyclopedia of Immunology. Encyclopedia of Immunology 2111 2116 .
Raimund W. Kinne, Ernesta Palombo-Kinne & Frank Emmrich. (1997) T-cells in the pathogenesis of rheumatoid arthritis Villains or accomplices?. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1360:2, pages 109-141.
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